JARO - Journal of the Association for Research in Otolaryngology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.NIDCD ’s 5-Year Strategic Plan Describes Scientific Priorities and Commitment to Basic Science
AbstractThe National Institute on Deafness and Other Communication Disorders (NIDCD) recently issued a new strategic plan that describes the institute ’s scientific priorities over the next five years. Developed in collaboration with informed stakeholders, the2023 –2027 NIDCD Strategic Plan: Advancing the Science of Communication to Improve Lives creates a unified vision to stimulate discoveries in basic research, model systems, innovative technologies, individualized treatment approaches, scientific data sharing, and translation of research findings into clinical practice. To further accelerate scientific discoveries,...
Source: JARO - Journal of the Association for Research in Otolaryngology - June 21, 2023 Category: ENT & OMF Source Type: research
An Inverse Relationship Between Gray Matter Volume and Speech-in-Noise Performance in Tinnitus Patients with Normal Hearing Sensitivity
In this study, pure-tone audiometry and Quick Speech-in-Noise test were conducted on individuals with tinnitus and normal hearing and hearing-matched controls. T1-weighted structural MRI images were obtained from all participants. After preprocessing, GM volumes were compared between tinnitus and control groups using whole-brain and region-of-interest analyses. Further, regression analyses were performed to examine the correlation between regional GM volume and SiN scores in each group. The results showed decreased GM volume in the right inferior frontal gyrus in the tinnitus group relative to the control group. In the tin...
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
Sensitivity to Pulse Rate and Amplitude Modulation in an Animal Model of the Auditory Brainstem Implant (ABI)
AbstractThe auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing by electrically stimulating the cochlear nucleus (CN) of the brainstem. Our previous study (McInturff et al., 2022) showed that single-pulse stimulation of the dorsal (D)CN subdivision with low levels of current evokes responses that have early latencies, different than the late response patterns observed from stimulation of the ventral (V)CN. How these differing responses encode more complex stimuli, such as pulse trains and amplitude modulated (AM) pulses, has not been explored. Here, we compare responses to pulse train stim...
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
Bandpass Shape of Distortion-Product Otoacoustic Emission Ratio Functions Reflects Cochlear Frequency Tuning in Normal-Hearing Mice
AbstractThe frequency selectivity of the mammalian auditory system is critical for discriminating complex sounds like speech. This selectivity derives from the sharp tuning of the cochlea ’s mechanical response to sound, which is largely attributed to the amplification of cochlear vibrations by outer hair cells (OHCs). Due to its nonlinearity, the amplification process also leads to the generation of distortion products (DPs), some of which propagate out to the ear canal as DP otoa coustic emissions (DPOAEs). However, the insight that these signals provide about the tuned micro- and macro-mechanics underlying their gener...
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
In Vivo Optical Characterization of Middle Ear Effusions and Biofilms During Otitis Media
This study provides an atlas of middle ear OCT images exhibiting a range of depth-resolved MEE features, which can only be visualized and assessed n on-invasively through OCT. Quantitative metrics of OCT images acquired prior to the surgery were statistically correlated with surgical evaluations of MEEs. Measurements of MEE characteristics will provide new readily available information that can lead to improved diagnosis and management strategie s for the highly prevalent OM in children. (Source: JARO - Journal of the Association for Research in Otolaryngology)
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
Finite-Element Modelling Based on Optical Coherence Tomography and Corresponding X-ray MicroCT Data for Three Human Middle Ears
ConclusionThis study provides an initial look at the combined use of OCT measurements and FE modelling based on subject-specific anatomy. The geometries and parameters of the existing FE models could be modified for individual patients in the future to help identify abnormalities in the middle ear. (Source: JARO - Journal of the Association for Research in Otolaryngology)
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
Nuclear Translocation Triggered at the Onset of Hearing in Cochlear Inner Hair Cells of Rats and Mice
ConclusionNuclear migration at the onset of hearing is a key step in the morphological maturation of IHCs. Whether this plays a role in functional maturation remains to be explored. (Source: JARO - Journal of the Association for Research in Otolaryngology)
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
Types of Inheritance and Genes Associated with Familial Meniere Disease
AbstractMeniere disease (MD) is a rare disorder of the inner ear defined by sensorineural hearing loss (SNHL) associated with episodes of vertigo and tinnitus. The phenotype is variable, and it may be associated with other comorbidities such as migraine, respiratory allergies, and several autoimmune disorders. The condition has a significant heritability according to epidemiological and familial segregation studies. Familial MD is found in 10% of cases, the most frequently found genes beingOTOG,MYO7A, andTECTA, previously associated with autosomal dominant and recessive non-syndromic SNHL. These findings suggest a new hypo...
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
Connexin36 RNA Expression in the Cochlear Nucleus of the Echolocating Bat, Eptesicus fuscus
ConclusionOur data suggest that the anatomical substrate for CX36-mediated electrical neurotransmission is conserved in the mammalian CN across echolocating bats and non-echolocating mice. (Source: JARO - Journal of the Association for Research in Otolaryngology)
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
NIDCD ’s 5-Year Strategic Plan Describes Scientific Priorities and Commitment to Basic Science
AbstractThe National Institute on Deafness and Other Communication Disorders (NIDCD) recently issued a new strategic plan that describes the institute ’s scientific priorities over the next five years. Developed in collaboration with informed stakeholders, the2023 –2027 NIDCD Strategic Plan: Advancing the Science of Communication to Improve Lives creates a unified vision to stimulate discoveries in basic research, model systems, innovative technologies, individualized treatment approaches, scientific data sharing, and translation of research findings into clinical practice. To further accelerate scientific discoveries,...
Source: JARO - Journal of the Association for Research in Otolaryngology - June 1, 2023 Category: ENT & OMF Source Type: research
In Vivo Optical Characterization of Middle Ear Effusions and Biofilms During Otitis Media
This study provides an atlas of middle ear OCT images exhibiting a range of depth-resolved MEE features, which can only be visualized and assessed n on-invasively through OCT. Quantitative metrics of OCT images acquired prior to the surgery were statistically correlated with surgical evaluations of MEEs. Measurements of MEE characteristics will provide new readily available information that can lead to improved diagnosis and management strategie s for the highly prevalent OM in children. (Source: JARO - Journal of the Association for Research in Otolaryngology)
Source: JARO - Journal of the Association for Research in Otolaryngology - May 30, 2023 Category: ENT & OMF Source Type: research
Connexin36 RNA Expression in the Cochlear Nucleus of the Echolocating Bat, Eptesicus fuscus
ConclusionOur data suggest that the anatomical substrate for CX36-mediated electrical neurotransmission is conserved in the mammalian CN across echolocating bats and non-echolocating mice. (Source: JARO - Journal of the Association for Research in Otolaryngology)
Source: JARO - Journal of the Association for Research in Otolaryngology - May 30, 2023 Category: ENT & OMF Source Type: research
Finite-Element Modelling Based on Optical Coherence Tomography and Corresponding X-ray MicroCT Data for Three Human Middle Ears
ConclusionThis study provides an initial look at the combined use of OCT measurements and FE modelling based on subject-specific anatomy. The geometries and parameters of the existing FE models could be modified for individual patients in the future to help identify abnormalities in the middle ear. (Source: JARO - Journal of the Association for Research in Otolaryngology)
Source: JARO - Journal of the Association for Research in Otolaryngology - May 10, 2023 Category: ENT & OMF Source Type: research
Sensitivity to Pulse Rate and Amplitude Modulation in an Animal Model of the Auditory Brainstem Implant (ABI)
AbstractThe auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing by electrically stimulating the cochlear nucleus (CN) of the brainstem. Our previous study (McInturff et al., 2022) showed that single-pulse stimulation of the dorsal (D)CN subdivision with low levels of current evokes responses that have early latencies, different than the late response patterns observed from stimulation of the ventral (V)CN. How these differing responses encode more complex stimuli, such as pulse trains and amplitude modulated (AM) pulses, has not been explored. Here, we compare responses to pulse train stim...
Source: JARO - Journal of the Association for Research in Otolaryngology - May 8, 2023 Category: ENT & OMF Source Type: research
Bandpass Shape of Distortion-Product Otoacoustic Emission Ratio Functions Reflects Cochlear Frequency Tuning in Normal-Hearing Mice
AbstractThe frequency selectivity of the mammalian auditory system is critical for discriminating complex sounds like speech. This selectivity derives from the sharp tuning of the cochlea ’s mechanical response to sound, which is largely attributed to the amplification of cochlear vibrations by outer hair cells (OHCs). Due to its nonlinearity, the amplification process also leads to the generation of distortion products (DPs), some of which propagate out to the ear canal as DP otoa coustic emissions (DPOAEs). However, the insight that these signals provide about the tuned micro- and macro-mechanics underlying their gener...
Source: JARO - Journal of the Association for Research in Otolaryngology - April 18, 2023 Category: ENT & OMF Source Type: research
