Japanese Journal of Clinical Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Feasibility of next-generation sequencing (Oncomine ™ DX Target Test) for the screening of oncogenic mutations in advanced non-small-cell lung cancer patients
ConclusionsTissue size and tumour cell content were significantly associated with the success rate of Oncomine ™ Dx Target Test companion diagnostics. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 21, 2021 Category: Cancer & Oncology Source Type: research

Erratum to: Response to Dr Shikata ’s letter: ‘Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies’
In the originally published version of this manuscript, there was an error in the title. The incorrect title wasResponse to the Dr Shikata's letter: `Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies'. The correct title isResponse to Dr Shikata's letter: `Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies'. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 21, 2021 Category: Cancer & Oncology Source Type: research

Age-specific skin cancer incidence rate in the world
(Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 21, 2021 Category: Cancer & Oncology Source Type: research

Novel hybrid endoscopy-assisted larynx-preserving esophagectomy for cervical esophageal cancer (with video)
AbstractHybrid endoscopy-assisted larynx-preserving esophagectomy is developed for cervical esophageal squamous cell carcinoma encroaching or extending above the upper esophageal sphincter. First, a cervical incision was surgically performed followed by cervical lymph node dissection. Second, the margin of cervical esophageal squamous cell carcinoma was endoscopically identified with iodine staining and marked endoscopically followed by semi-circumferential or circumferential endoscopic full-thickness excision around the lumen of the esophagus. The distal margin was surgically resected and reconstruction was performed. Amo...
Source: Japanese Journal of Clinical Oncology - April 14, 2021 Category: Cancer & Oncology Source Type: research

Coverage of the hospital-based cancer registries and the designated cancer care hospitals in Japan
ConclusionsThe hospital-based cancer registry coverage is ~70% of all cancers. Because the coverage differed across cancers and age groups, the respective target groups ’ analysis should consider this factor. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 14, 2021 Category: Cancer & Oncology Source Type: research

Transarterial management of advance lung cancer
AbstractPrevious reports on transarterial treatment for lung cancer were reviewed. The bronchial arterial infusion therapy has a long history since 1964. Better local control with less doses of anti-neoplastic agents was warranted by trying transarterial administration to lung and mediastinal tumors. It is reported that both primary and metastatic tumors are fed by bronchial or other systemic arteries. The bronchial arterial embolization for hemoptysis has been introduced for clinical practice since 1973. Hemoptysis by not only benign but also malignant diseases has been well controlled by embolization. In recent decades, ...
Source: Japanese Journal of Clinical Oncology - April 14, 2021 Category: Cancer & Oncology Source Type: research

Histopathological atlas of desmoplastic reaction characterization in colorectal cancer
AbstractEmergent scientific evidence indicates the central role of cancer-associated fibroblasts in determining whether the microenvironment of cancer works as friend or foe of the host; however, there is no unified histological evaluation framework of fibrotic stroma in colorectal cancers. Myxoid stroma and keloid-like collagen are site-specific histopathological features generated by cancer-associated fibroblasts, which appear exclusively in the tumor front during desmoplastic reaction. On the basis of these two stromal components, desmoplastic reaction is categorized into three patterns —immature, intermediate and mat...
Source: Japanese Journal of Clinical Oncology - April 14, 2021 Category: Cancer & Oncology Source Type: research

A novel osimertinib-resistant human lung adenocarcinoma cell line harbouring mutant EGFR and activated IGF1R
ConclusionsTaken together, we have successfully established a new osimertinib-resistant lung adenocarcinoma cell line with activated IGF1R. These ABC-31 cells will help develop novel therapeutic strategies for patients with lung adenocarcinoma resistant to specific treatment via IGF1R activation. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 7, 2021 Category: Cancer & Oncology Source Type: research

Benefit of surgical resection of distant metastasis in soft tissue sarcoma: a systematic review
ConclusionsAlthough the level of evidence is very low, many retrospective studies support a clinical advantage for metastasectomy, and surgical indications should be carefully considered for patients with metastasis from soft tissue sarcoma. Metastasectomy is an option for patients with metastasis and should be done only if it can be performed safely and if potential advantages outweigh disadvantages. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 6, 2021 Category: Cancer & Oncology Source Type: research

Sarcopenia and obesity in long-term survivors of childhood leukemia/lymphoma: a report from a single institution
ConclusionsYoung adult survivors of childhood leukemia/lymphoma could be at risk of developing sarcopenia after hematopoietic stem cell transplantation and obesity after cranial radiotherapy. Further studies are required to assess the body composition of long-term survivors to find detailed risk factors of sarcopenia and metabolic syndrome. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 6, 2021 Category: Cancer & Oncology Source Type: research

Is perioperative chemotherapy recommended in childhood and adolescent patients with synovial sarcoma? A systematic review
ConclusionsWe weakly do not recommend perioperative chemotherapy in patients with non-metastatic synovial sarcoma  ≤ 5 cm when R0 resection is acquired. There was no consensus concerning the role of perioperative chemotherapy in patients with synovial sarcoma >  5 cm or those with ≤5 cm who undergo R1 or R2 resection. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 6, 2021 Category: Cancer & Oncology Source Type: research

Septic phlebitis of the liver presenting as fever of unknown origin detected by FDG PET/CT
Guangdong Medical Science and Technology Research FoundationA2021116 (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 5, 2021 Category: Cancer & Oncology Source Type: research

Post-operative small pelvic intensity-modulated radiation therapy for early-stage cervical cancer with intermediate-risk factors: efficacy and toxicity
ConclusionsFor early-stage cervical cancer patients with intermediate-risk factors, post-operative small pelvic intensity-modulated radiotherapy was safe and well tolerated. The rates of acute and late toxicities were quite satisfactory. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 5, 2021 Category: Cancer & Oncology Source Type: research

Fibroblast growth factor receptor 2 (FGFR2) fusions in Japanese patients with intrahepatic cholangiocarcinoma
ConclusionsFurther detailed elucidation of fibroblast growth factor receptor 2 fusion status is expected to contribute to the development of promising therapeutic options for patients suffering from recurrent or unresectable intrahepatic cholangiocarcinoma. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 3, 2021 Category: Cancer & Oncology Source Type: research

Soft tissue sarcoma in adolescent and young adult patients: a retrospective study using a nationwide bone and soft tissue tumor registry in Japan
ConclusionsOur study is the first to investigate soft tissue sarcoma in adolescent and young adult patients using the nationwide Bone and Soft Tissue Tumor registry. Adolescent and young adult age is not a prognostic factor for poor cancer survival among those with soft tissue sarcoma in Japan. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - April 1, 2021 Category: Cancer & Oncology Source Type: research