Progress of computer-aided detection/diagnosis (CAD) in dentistry & lt;Runningtitle & gt;CAD in dentistry & lt;/Runningtitle & gt;
Publication date: August 2014 Source:Japanese Dental Science Review, Volume 50, Issue 3 Author(s): Akitoshi Katsumata, Hiroshi Fujita The development of computer-aided detection/diagnosis (CAD) systems for dental imaging is progressing. One expected use of CAD is to detect radiological signs of medical systemic disease in the panoramic screening radiograph. The target diseases for CAD include osteoporosis, arteriosclerosis, and maxillary sinusitis. CAD is also useful in the detection and evaluation of dental and maxillofacial lesions. Identifying alveolar bone resorption due to periodontitis and radiolucent jaw lesions...
Source: Japanese Dental Science Review - June 18, 2016 Category: Dentistry Source Type: research

Development of technique for in vitro embryotoxicity of dental biomaterials
Publication date: Available online 11 June 2016 Source:Japanese Dental Science Review Author(s): Koichi Imai The Embryonic Stem Cell Test (EST) developed in Germany in 1997 is known as a screening test method capable of predicting the presence of unknown chemicals influencing normal human development. Firstly, we investigated the embryotoxicity of 24 types of monomer including dental monomers and dental alloy-component metal elements using this test. Monomers including Bis-GMA contained in base resin of composite resin exhibited weak embryotoxicity, and the toxicity level varied among dental alloy-component metal elemen...
Source: Japanese Dental Science Review - June 11, 2016 Category: Dentistry Source Type: research

A controversy with respect to occlusion
Publication date: Available online 26 May 2016 Source:Japanese Dental Science Review Author(s): Shunji Fukushima There are very little controversies on occlusion in healthy individuals, where centric relation is regarded as the criterion for assessing the present occlusion and also for establishing a new occlusal relationship between the upper and the lower jaws. On the other hand, the occlusal position in patients with deformed condyles still remains to be clarified. In this review, the effectiveness and limits of centric relation in these patients are discussed. In addition, the muscle induced occlusal positions, such...
Source: Japanese Dental Science Review - May 26, 2016 Category: Dentistry Source Type: research

Molecular characterization and function of tenomodulin, a marker of tendons and ligaments that integrate musculoskeletal components
Publication date: Available online 27 April 2016 Source:Japanese Dental Science Review Author(s): Chisa Shukunami, Yuki Yoshimoto, Aki Takimoto, Hiroshi Yamashita, Yuji Hiraki Tendons and ligaments are dense fibrous bands of connective tissue that integrate musculoskeletal components in vertebrates. Tendons connect skeletal muscles to the bone and function as mechanical force transmitters, whereas ligaments bind adjacent bones together to stabilize joints and restrict unwanted joint movement. Fibroblasts residing in tendons and ligaments are called tenocytes and ligamentocytes, respectively. Tenomodulin (Tnmd) is a ...
Source: Japanese Dental Science Review - May 10, 2016 Category: Dentistry Source Type: research

Histology of human cementum: Its structure, function, and development
Publication date: Available online 27 April 2016 Source:Japanese Dental Science Review Author(s): Tsuneyuki Yamamoto, Tomoka Hasegawa, Tomomaya Yamamoto, Hiromi Hongo, Norio Amizuka Cementum was first demonstrated by microscopy, about 180 years ago. Since then the biology of cementum has been investigated by the most advanced techniques and equipment at that time in various fields of dental sciences. A great deal of data on cementum histology have been accumulated. These data have been obtained from not only human, but also non-human animals, in particular, rodents such as the mouse and rat. Although many dental his...
Source: Japanese Dental Science Review - May 10, 2016 Category: Dentistry Source Type: research

Role of the Wnt signaling molecules in the tooth
Publication date: Available online 5 May 2016 Source:Japanese Dental Science Review Author(s): Masato Tamura, Eiji Nemoto Wnt signaling plays a central role in many processes during embryonic development and adult homeostasis. At least 19 types of Wnt ligands, receptors, transducers, transcription factors, and antagonists have been identified in mammals. Two distinct Wnt signaling pathways, the canonical signaling pathway and the noncanonical signaling pathway, have been described. Some Wnt signaling pathway components are expressed in the dental epithelium and mesenchyme during tooth development in humans and mice. Fu...
Source: Japanese Dental Science Review - May 10, 2016 Category: Dentistry Source Type: research

Rho GTPases in ameloblast differentiation
Publication date: Available online 11 December 2015 Source:Japanese Dental Science Review Author(s): Keishi Otsu, Hidemitsu Harada During tooth development, ameloblasts differentiate from inner enamel epithelial cells to enamel-forming cells by modulating the signal pathways mediating epithelial–mesenchymal interaction and a cell-autonomous gene network. The differentiation process of epithelial cells is characterized by marked changes in their morphology and polarity, accompanied by dynamic cytoskeletal reorganization and changes in cell–cell and cell–matrix adhesion over time. Functional ameloblasts...
Source: Japanese Dental Science Review - December 12, 2015 Category: Dentistry Source Type: research

Masticatory muscle tendon-aponeurosis hyperplasia: A new clinical entity of limited mouth opening
Publication date: Available online 9 December 2015 Source:Japanese Dental Science Review Author(s): Tsuyoshi Sato, Tetsuya Yoda Limited mouth opening is a common health problem that interferes with eating, makes examination of the oral cavity difficult, and may increase the mortality rate during emergency intubation. Here we introduce a disease designated as masticatory muscle tendon-aponeurosis hyperplasia, which is a new clinical condition of limited mouth opening. Most oral surgeons and dentists are still unaware of this disease condition, thus increasing the risk of incorrect diagnosis as some other disease, such a...
Source: Japanese Dental Science Review - December 11, 2015 Category: Dentistry Source Type: research

Exopeptidases and gingipains in Porphyromonas gingivalis as prerequisites for its amino acid metabolism
Publication date: Available online 26 September 2015 Source:Japanese Dental Science Review Author(s): Takayuki K. Nemoto, Yuko Ohara-Nemoto Porphyromonas gingivalis, an asaccharolytic bacterium, utilizes amino acids as energy and carbon sources. Since amino acids are incorporated into the bacterial cells mainly as di- and tri-peptides, exopeptidases including dipeptidyl-peptidase (DPP) and tripeptidyl-peptidase are considered to be prerequisite components for their metabolism. We recently discovered DPP11, DPP5, and acylpeptidyl oligopeptidase in addition to previously reported DPP4, DPP7, and prolyl tripeptidyl peptid...
Source: Japanese Dental Science Review - September 26, 2015 Category: Dentistry Source Type: research

Production and physiological role of NO in the oral cavity
Publication date: Available online 11 September 2015 Source:Japanese Dental Science Review Author(s): Kimiharu Ambe, Hiroki Watanabe, Shinya Takahashi, Toshihiro Nakagawa, Junzo Sasaki Nitric oxide (NO) is a free radical which is produced from a wide variety of cells and tissues in the human body. NO is involved in the regulation of many physiological processes, such as vascular relaxation, neurotransmission, immune regulation, and cell death. NO is generated by nitric oxide synthase (NOS), which has three identified isoforms: neuronal type NOS (nNOS), endothelial type NOS (eNOS), and inducible type NOS (iNOS). Diff...
Source: Japanese Dental Science Review - September 11, 2015 Category: Dentistry Source Type: research

Dental prostheses mimic the natural enamel behavior under functional loading: A review article
Publication date: Available online 1 September 2015 Source:Japanese Dental Science Review Author(s): Ahmed A. Madfa, Xiao-Guang Yue Alumina- and zirconia-based ceramic dental restorations are designed to repair functionality as well as esthetics of the failed teeth. However, these materials exhibited several performance deficiencies such as fracture, poor esthetic properties of ceramic cores (particularly zirconia cores), and difficulty in accomplishing a strong ceramic–resin-based cement bond. Therefore, improving the mechanical properties of these ceramic materials is of great interest in a wide range of discip...
Source: Japanese Dental Science Review - September 2, 2015 Category: Dentistry Source Type: research

Structural factors affecting prosthodontic decision making in Japan
Publication date: Available online 19 May 2015 Source:Japanese Dental Science Review Author(s): Noriyuki Wakabayashi , Junichiro Wada Prosthodontic treatment strategies, prosthetic designs and materials, and treatment procedures are not determined solely by the diagnosis. We discuss the major effect of structural factors surrounding prosthodontic care on treatment decisions in Japan. These structural factors are related to the dentist, such as the dentist's education, postgraduate courses, and access to the latest research, and to the health care support system, including the social insurance system. Education content fr...
Source: Japanese Dental Science Review - June 14, 2015 Category: Dentistry Source Type: research

Epigenetic regulation of chondrocyte differentiation
Publication date: Available online 11 June 2015 Source:Japanese Dental Science Review Author(s): Kenji Hata Chondrocytes play an essential role in endochondral bone development, which is requisite for mammalian skeletal development. During endochondral bone development, chondrocytes undergo well-organized stages of sequential differentiation, including proliferation and hypertrophy, a process harmoniously modulated by various transcription factors. Epigenetics, including DNA methylation and histone modification, has recently emerged as an essential regulatory system for gene expression, not only in physiological conditio...
Source: Japanese Dental Science Review - June 14, 2015 Category: Dentistry Source Type: research

Synthesis and modification of apatite nanoparticles for use in dental and medical applications
Publication date: Available online 4 May 2015 Source:Japanese Dental Science Review Author(s): Masahiro Okada , Takuya Matsumoto Synthesised hydroxyapatite (HAp) exhibits excellent biocompatibility, making it an ideal candidate for use as a hard tissue substitute material. Nanoscale-size effects and surface phenomena impart HAp nanoparticles with unique properties compared to the conventional-sized HAp ceramics. Modification of HAp is also important for regulating its physiochemical properties. In this review, methods of HAp synthesis and modification, and various applications of HAp nanoparticles for dental and medical ...
Source: Japanese Dental Science Review - May 5, 2015 Category: Dentistry Source Type: research

Education on tobacco use interventions for undergraduate dental students
Publication date: Available online 11 April 2015 Source:Japanese Dental Science Review Author(s): Takashi Hanioka , Miki Ojima , Yoko Kawaguchi , Yukio Hirata , Hiroshi Ogawa , Daisuke Hinode , Nobuhiro Hanada , Eiji Inoshita Inadequate training for dental professionals hampers the implementation of tobacco use interventions for the improvement of dental practice and oral and overall health. To improve dental education regarding tobacco use prevention and cessation (DENTUPAC), we examined literature addressing previous efforts and experiences with this goal. The majority of studies, published in the US and Europe, report...
Source: Japanese Dental Science Review - May 4, 2015 Category: Dentistry Source Type: research

Ability of stem and progenitor cells in the dental pulp to form hard tissue
Publication date: Available online 18 April 2015 Source:Japanese Dental Science Review Author(s): Akihiro Hosoya , Hiroaki Nakamura Dental pulp has an important ability to form mineralized hard tissue in response to a variety of external stimuli. The formation of mineralized tissue within the pulp cavity has been widely examined in both clinical and animal studies. Despite these studies focusing on the phenomena of reparative dentin and dentin bridge formation, the mechanisms of their induction remain unknown. Recently, several morphological studies revealed that the source of cells for hard tissue formation is the denta...
Source: Japanese Dental Science Review - May 4, 2015 Category: Dentistry Source Type: research

Innate immunity to Candida albicans
Publication date: Available online 17 January 2015 Source:Japanese Dental Science Review Author(s): Yusuke Kiyoura , Riyoko Tamai Candida albicans is not a pathogen in healthy individuals, but can cause severe systemic candidiasis in immunocompromised patients. C. albicans has various virulence factors and activates the innate immune system. Specifically, C. albicans induces proinflammatory cytokine production in various cell types via many receptors, such as Toll-like receptors (TLRs) and C-type lectin receptors (CLRs). This microorganism also promotes phagocytosis via CLRs on macrophages. In a previous study, we found ...
Source: Japanese Dental Science Review - January 27, 2015 Category: Dentistry Source Type: research

Angiotensin II and taste sensitivity
Publication date: Available online 25 November 2014 Source:Japanese Dental Science Review Author(s): Noriatsu Shigemura The sense of taste plays a major role in evaluating the quality of food components in the oral cavity. Sweet, salty, umami, sour and bitter taste are generally accepted as five basic taste qualities. Among them, salty taste is attractive to animals and influences sodium intake. Angiotensin II (ANG II) and aldosterone (ALDO, which is stimulated by ANG II) are key hormones that regulate sodium homeostasis and water balance. At the peripheral gustatory organs, it has been reported that ALDO increases the a...
Source: Japanese Dental Science Review - November 25, 2014 Category: Dentistry Source Type: research

How masticatory function and periodontal disease relate to senile dementia
This study reviews the research of dementia, a pathology for which numerous studies have found associations with masticatory function in the elderly. These issues are presently major problems in geriatric medical and welfare settings, and we discuss the prospects for future research into mastication. Dementia and masticatory function have been examined in a range of epidemiological and neuroscientific studies, and associations between the two have been reported. However, a causal relationship has not been satisfactorily established. Biochemical studies have also clarified the basis of the association between dementia and p...
Source: Japanese Dental Science Review - November 15, 2014 Category: Dentistry Source Type: research

Developing role of dental hygienists in Japan
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Takuo Ishii , Yoshinobu Maki , Soichiro Hirata In Japan, the profession of the dental hygienist was created at the behest of GHQ in 1948, and as such forms part of the occupation's contribution to public health against a backdrop of postwar politics. The law was revised seven years later, allowing dental hygienists to assist in dental practice, particularly at dental clinics/hospitals. The number of dental hygienists currently exceeds 100,000, which is greater than the number of both dentists and dental technicians. This ma...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Exploring the possible applications of catechin (gel) for oral care of the elderly and disabled individuals
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Muneaki Tamura , Kuniyasu Ochiai The oral cavity contains more than hundreds of microbial species. An increase in the number of these microorganisms like high pathogenic potential species, such as cariogenic and periodontopathic bacteria, and the change of microbial biota may result in, not only oral infection, but also systemic diseases, such as infective endocarditis and aspiration pneumonia. It is very important to control the growth of these microorganisms and its biota just after oral cleaning in order to suppress dise...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Antibacterial resin monomers based on quaternary ammonium and their benefits in restorative dentistry
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Satoshi Imazato , Ji-hua Chen , Sai Ma , Naomi Izutani , Fang Li Antibacterial resin monomers are unique molecules that provide dental resins with “bio-active function”, i.e. the ability to control bacterial infection. They have strong antibacterial activity when unpolymerized and also demonstrate contact inhibitory effects after being polymerized without releasing antibacterial components. Intensive research has been conducted on antibacterial monomers based on quaternary ammonium, such as methacryloyloxydodecy...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

CCN2: A novel conductor in orchestration of orofacial tissue development and remodeling
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Akira Yamaguchi (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

CCN2 in orofacial tissue development and remodeling
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Satoshi Kubota CCN2 is one of the representative members of the CCN family, a group of proteins that orchestrate the extracellular signaling network. As anticipated by the original name, connective tissue growth factor, this molecule promotes the growth and development of mesenchymal tissues, including bone and cartilage. Indeed, CCN2 is required for the proper development of the orofacial region, which requirement is typically suggested by the frequent emergence of cleft palate in CCN2-null mice. The significant contributi...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Periostin: A multifunctional matricellular protein refocused in dental science
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Keiji Moriyama (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Periostin in dental science
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Issei Takayama , Akira Kudo In this mini-review, we focus on periostin, a matricellular protein that is preferentially expressed in cells such as fibroblastic cells in the periodontal ligament (PDL) and osteoblastic cells on the alveolar bone surfaces. Since the abnormal phenotypes of periostin-deficient mice in periodontal tissues have been reported over the last 5 years, we would like to summarize the action of this protein in the PDL, including our unpublished results. Following these results, we hypothesize the function...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

MR imaging diagnostic protocol for unilocular lesions of the jaw
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Hironobu Konouchi , Yoshinobu Yanagi , Miki Hisatomi , Hidenobu Matsuzaki , Toshihiko Takenobu , Teruhisa Unetsubo , Jun-ichi Asaumi Ameloblastomas and keratocystic odontogenic tumors (KCOT) are typical jawbone tumors. In addition, dentigerous cysts (DC) and radicular cysts are the most common cystic jawbone lesions, and simple bone cysts (SBC) are the most common jawbone pseudocysts. When these lesions are unilocular, it can be difficult to diagnose them by radiography. In recent years, adding magnetic resonance (MR) imagi...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Tongue and upper airway function in subjects with and without obstructive sleep apnea
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Takashi Ono Obstructive sleep apnea (OSA) is characterized by repeated occlusion of the oropharyngeal airway during sleep and can have a significant impact on quality of life. In this article, I review the current knowledge of the physiological and pathological functions of the tongue and the genioglossus muscle, one of the upper airway dilatory muscles, in subjects with OSA when they are awake and asleep. Research findings clearly reveal that the genioglossus muscle has important functions in maintenance of upper airway pa...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

The neuro-osteogenic network: The sympathetic regulation of bone resorption
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Akifumi Togari , Michitsugu Arai , Hisataka Kondo , Daisuke Kodama , Yuka Niwa Bone is innervated by sympathetic and sensory neurons, which play important roles in bone remodeling. Direct neuro-osteogenic cross-talk has been demonstrated using an in vitro co-culture model comprising osteoblastic or osteoclastic cells, and neurite-spouting mouse superior cervical ganglia, suggesting that these cells are directly regulated by sympathetic neurons. The increase in sympathetic nervous activity causes bone loss through increased ...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Tobacco interventions by dentists and dental hygienists
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Takashi Hanioka , Miki Ojima , Yoko Kawaguchi , Yukio Hirata , Hiroshi Ogawa , Yumiko Mochizuki Tobacco use is a modifiable risk factor for oral disease. Dental professionals are able to reduce the burden of oral and overall health by influencing tobacco use. Results of electronic searches for literature indicated progress in tobacco interventions in dentistry. Patients believed that dentists should routinely offer smoking cessation services, and those interested in quitting felt comfortable receiving advice about quittin...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Research on the mesenchymal stem cells in the maxillo-facial region and bone tissue regeneration
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Makoto Tsuchimochi (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Bone regeneration from mesenchymal stem cells (MSCs) and compact bone-derived MSCs as an animal model
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Eiki Yamachika , Seiji Iida Mesenchymal stem cells (MSCs) have emerged as a promising alternative to traditional surgical techniques. The purpose of this review is to document the current state of research and identify future research directions. At present, no specific markers have been shown to specifically identify MSCs. The most commonly reported positive markers are CD105, CD90, CD44, CD73, CD29, CD13, CD34, CD146, CD106, CD54 and CD166. The most frequently reported negative markers are CD34, CD14, CD45, CD11b, CD49d...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

New tachykinin peptides and nociception
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Toshikazu Nishimori , Rumi Naono-Nakayama , Tetsuya Ikeda Hemokinin-1 (HK-1) and endokinins are peptides predicted from a new mammalian tachykinin gene, TAC4. The amino acid sequences derived from rat/mouse HK-1 and human HK-1 are not identical; however, the effects induced by intracerebroventricular or intrathecal administration of HK-1 are attenuated by treatment with antagonists of neurokinin 1 (NK1) receptor, substance P (SP) receptor, indicating that HK-1 is an agonist of the NK1 receptor. On the other hand, a growin...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Review scaffold design and stem cells for tooth regeneration
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Li Zhang , Yosry Morsi , Yanying Wang , Yubao Li , Seeram Ramakrishna Current dental treatments for the missing teeth depend largely on dentures and implants crowned with prosthetic caps to restore some functionality of the teeth. However, these devices cannot mimic the biological teeth, do not remodel and they have poor integration with the host. The concept of tissue engineering is based on that fact that by cultivating postnatal dental stem cells (DSCs) on a well-designed bioengineered three dimensional scaffold, it is...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

The dawn of modern dentistry in Japan: The transfer of knowledge and skills from foreign dentists to Japanese counterparts in the Yokohama Foreign Settlement
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Toshihide Ohno , Yuji Hasaka Modern Western dentistry was introduced to Japan by foreign dentists who arrived in Yokohama, after the opening of the country. The arrival in Japan of foreign dentists triggered the introduction of modern dentistry into Japan. We searched through advertisements in the English and Japanese language newspapers published in the Yokohama Settlement to trace the footsteps of these foreign dentists. This paper traces the early history of modern dentistry in Japan from 1865 to 1912 by dividing the p...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Cell cycle control factors and skeletal development
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Toru Ogasawara In the oral and maxillofacial region, conditions such as delayed bone healing after tooth extraction, bone fracture, trauma-induced bone or cartilage defects, and tumors or birth defects are common, and it is necessary to identify the molecular mechanisms that control skeletogenesis or the differentiation of cells, in order to establish new treatment strategies for these conditions. Multiple studies have been conducted to investigate the involvement of factors that may be crucial for skeletogenesis or the differ...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Medical microbiological approach to Archaea in oral infectious diseases
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Hiroshi Maeda , Kimito Hirai , Junji Mineshiba , Tadashi Yamamoto , Susumu Kokeguchi , Shogo Takashiba Recent advances in molecular biological techniques have yielded large amounts of information regarding the oral microflora. The microbiological communities were shown to be more diverse than previously thought and to include a number of previously uncharacterized microorganisms. The range of research targets of microorganisms associated with oral diseases has been expanded to include these unknown or uncharacterized organisms...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Octacalcium phosphate (OCP)-based bone substitute materials
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Osamu Suzuki The present article summarizes the characteristics of a synthetic octacalcium phosphate (OCP) and OCP-based materials. We previously established a method for a relatively large scale synthesis of OCP and showed that OCP enhances bone regeneration more than hydroxyapatite (HA) materials, including HA obtained through hydrolysis of OCP, coupled with material biodegradation if implanted in various bone defects. One of the OCP-based materials consisting of OCP and natural polymers, such as gelatin, induced a bone rege...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

The dawn of modern dentistry in Japan
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Masashi Sugisaki (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Detection of field alterations using useful tools for oral squamous cell carcinoma
Publication date: August 2013 Source:Japanese Dental Science Review, Volume 49, Issue 3 Author(s): Takeshi Nomura , Takahiko Shibahara It is known that a region of epithelial dysplasia cannot easily be distinguished macroscopically from normal looking area surrounding early oral squamous cell carcinoma (OSCC). In 1953, Slaughter emphasized field cancerization and the importance of examining the fields surrounding OSCC. Since 1997, we have used vital staining with iodine for detecting surgical margin and investigated the usefulness of this method. From a pathological point of view, various types of dysplasia in iodine uns...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Income and expenditure in private dental clinics in Japan
Publication date: August 2013 Source:Japanese Dental Science Review, Volume 49, Issue 3 Author(s): Midori Tsuneishi , Tatsuo Yamamoto , Takuo Ishii Although national dental care expenditure has not changed, the number of dental clinics has increased. Mass media has been reporting on the financial difficulties of dental clinics. To address this issue, we reviewed articles that showed the distribution and changes in net income, that is, total expenses subtracted from total income, of private dental clinics in Japan using data from a survey conducted by the Japan Dental Association. We also reviewed articles analyzing the f...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Guideline of primary treatment of temporomandibular disorders using GRADE approach
Publication date: August 2013 Source:Japanese Dental Science Review, Volume 49, Issue 3 Author(s): Masashi Sugisaki (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Primary treatment of temporomandibular disorders: The Japanese Society for the temporomandibular joint evidence-based clinical practice guidelines, 2nd edition
Publication date: August 2013 Source:Japanese Dental Science Review, Volume 49, Issue 3 Author(s): Hidemichi Yuasa , Koji Kino , Eiro Kubota , Kenji Kakudo , Masashi Sugisaki , Akira Nishiyama , Yoshizo Matsuka , Nobumi Ogi In 2010 and 2012, the clinical practice guidelines committee of the Japanese Society for the temporomandibular joint published clinical guidelines for the primary treatment of temporomandibular disorders (TMDs) using the principles of evidence-based medicine (EBM) and the grading of recommendations assessment, development and evaluation (GRADE) approach. In the present review, we provide the results o...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Growth of the mandible and biological characteristics of the mandibular condylar cartilage
Publication date: November 2013 Source:Japanese Dental Science Review, Volume 49, Issue 4 Author(s): Itaru Mizoguchi , Naoko Toriya , Yuya Nakao Mandibular condylar cartilage is the center of greatest growth in the craniofacial complex, and is associated with maxillofacial skeleton morphogenesis and temporomandibular joint function. The condylar process grows in a wide range of directions from anterosuperior to posterior, resulting in highly diverse mandibular growth and morphology. Condylar growth direction is closely related to mandibular displacement direction and vertical jaw deviations (i.e., high or low angle). Con...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Effectiveness of preemptive analgesia on postoperative pain following third molar surgery: Review of literatures
Publication date: November 2013 Source:Japanese Dental Science Review, Volume 49, Issue 4 Author(s): Akira Yamaguchi , Kimito Sano We investigated the efficacy of preemptive analgesia for mandibular third molar surgery by, reviewing of randomized controlled trials. In many of the studies, the preemptive use of NSAIDs before, tooth extraction demonstrated that the postoperative pain was better controlled beyond the expected, effect time, compared without such preemptive use. On the other hand, some studies reported that, compared to the administration before removal of the tooth, postoperative administration was, associat...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Possible functional scaffolds for periodontal regeneration
Publication date: November 2013 Source:Japanese Dental Science Review, Volume 49, Issue 4 Author(s): Hidetoshi Shimauchi , Eiji Nemoto , Hiroshi Ishihata , Masatsugu Shimomura Periodontal diseases are the most prevalent infectious diseases with the irreversible loss of tooth supporting apparatus. To reestablish the stable health of periodontal tissues after healing, the concept of regenerative surgical procedures has been developed over the past three decades, including various grafting materials, guided tissue regeneration (GTR), and the use of enamel matrix derivatives (EMD) in a clinical setting. More recently, tissue...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Mandibular condylar cartilage is a pivotal organ for articulation as well as growth and development
Publication date: November 2013 Source:Japanese Dental Science Review, Volume 49, Issue 4 Author(s): Keiji Moriyama (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Oral health and general health at the early stage of ageing: A review of contemporary studies
Publication date: February 2014 Source:Japanese Dental Science Review, Volume 50, Issue 1 Author(s): Shingo Moriya , Hiroko Miura In 2012, persons over age 65 reached 24.1% of Japan's population, and this population will continue to grow. The relationship between oral health and general health has been examined in many studies, geriatric dentistry in particular. An increasing need for long-term care for older adults is expected with the ageing of Japan's population. This will result in escalating costs for these services; thus, we are now prompted to identify predictors for eligibility for long-term care funding. Recent ...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

Nutrition and oral status in elderly people
This study reviewed the relationship between oral status and nutritional disorders such as obesity and sarcopenia. A literature search was performed using PubMed to find articles published in and after 2000 by using the following search terms: elderly, nutrition, tooth, tooth loss, mastication, and oral function. Although the literature search revealed that further well-designed studies are difficult controlling all confounding factors thought to influence nutritional status, it may be concluded that tooth loss leads to decreased vegetable and fruit intake and results in nutritional disturbance. This was especially promine...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research

The pathophysiology of heterotopic ossification: Current treatment considerations in dentistry
Publication date: February 2014 Source:Japanese Dental Science Review, Volume 50, Issue 1 Author(s): Kengo Shimono , Kenta Uchibe , Takuo Kuboki , Masahiro Iwamoto Heterotopic ossification (HO) consists of the formation of ectopic cartilage followed by endochondral bone, and is triggered by major surgeries, large wounds, and other conditions. Daily functions of HO patients can be hampered by the loss of normal posture, pain, inflammation, reduced mobility, formation of pressure ulcers, deep venous thrombosis, and other complications. Research so far revealed the molecular and cellular pathways leading HO formation, and p...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research