Considerations in Early Autism Diagnosis
To the Editor Early diagnosis is regarded as a cornerstone of modern medicine as it allows early treatment and hence better outcomes. Autism spectrum disorder (ASD) diagnosis is no exception, and this belief has in turn prompted the implementation of screening tests in toddlers in an attempt to diagnose autism at a very early age. However, there are 2 important caveats to this approach. First, it relies on the accuracy of the diagnostic, screening, or risk prediction tests. Second, to justify this approach, there should be a treatment for the condition, and the efficacy of treatment should improve when the condition is dia...
Source: JAMA Pediatrics - February 5, 2024 Category: Pediatrics Source Type: research
Considerations in Early Autism Diagnosis
To the Editor We read with interest the study by Harstad et al, which concluded that 37% of the sample with higher baseline adaptive functioning scores and female sex did not maintain the diagnosis of autism spectrum disorder (ASD). We extend this scientific discourse with 3 additional points that necessitate further inquiry. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - February 5, 2024 Category: Pediatrics Source Type: research
Survey of Neonatal Management After Amnioinfusion
This survey study reports on use of renal replacement therapy, hemodynamic support, sedation, neuroimaging, and extracorporeal membrane oxygenation at Renal Anhydramnios Fetal Therapy trial sites for neonates with either bilateral renal agenesis or fetal kidney failure. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - February 5, 2024 Category: Pediatrics Source Type: research
JAMA Pediatrics
Vision: JAMA Pediatrics will be the most respected source of information for investigators, providers, and policy makers seeking the highest quality evidence to guide decision-making. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - February 1, 2024 Category: Pediatrics Source Type: research
A Strategy for Artificial Intelligence With Clinical Impact
This Viewpoint describes a strategy for addressing major challenges in artificial intelligence in pediatrics to maximize clinical impact. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 29, 2024 Category: Pediatrics Source Type: research
Physical Activity and Mental Health in Children and Adolescents With Neurodevelopmental Disorders
This systematic review and meta-analysis assesses the association of physical activity interventions and mental health in children and adolescents with neurodevelopmental disorders. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 29, 2024 Category: Pediatrics Source Type: research
Definitional and Methodological Study of Pediatric Post –COVID-19 Condition—Reply
In Reply We thank Murdoch et al for their interest in our pediatric post –COVID-19 condition (PCC) research. Contrary to their suggestion, we believe our work is consistent with the referenced 2022 and 2023 World Health Organization (WHO) definitions of PCC. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 29, 2024 Category: Pediatrics Source Type: research
Definitional and Methodological Study of Pediatric Post –COVID-19 Condition
To the Editor The Research Letter by Hahn et al draws an invalid conclusion that the incidence of post –COVID-19 condition (PCC), as defined by the World Health Organization (WHO), is strikingly low in children. The authors cite an informal summary definition of PCC in their Introduction, then in the Methods section change the definition’s symptom time frame from after 3 months postinfection to w ithin 3 months. The formal WHO definition is concerned with symptoms after 3 months, meaning the research did not study PCC as cited and cannot draw conclusions about PCC. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 29, 2024 Category: Pediatrics Source Type: research
Substance Use, Suicidal Thoughts, and Psychiatric Comorbidities
This cross-sectional study evaluates the dose-dependent association between alcohol, cannabis, and nicotine use and psychiatric symptoms among participants in the Substance Use and Risk Factor Survey and the Youth Risk Behavior Survey. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 29, 2024 Category: Pediatrics Source Type: research
What Parents Need to Know About Penicillin Allergy Labels
This JAMA Pediatrics Patient Page describes why it is important for children to see their pediatrician for any concern about a reaction to penicillin before a child is considered to have a penicillin allergy. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 29, 2024 Category: Pediatrics Source Type: research
Nonsugar Sweeteners —Time for Transparency and Caution
This Viewpoint discusses the growing presence of nonsugar sweeteners (NSSs) in the food supply and mounting concerns about their use, which suggest that disclosure of the amounts of NSS in food and beverages and restrictions on their use in products marketed to children are warranted. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research
In Utero Exposure to Maternal COVID-19 Vaccination and Offspring Neurodevelopment at 12 and 18 Months
This cohort study investigates the association between previous exposure to maternal COVID-19 vaccination in utero and risk for neurodevelopmental impairment in infants aged 12 and 18 months. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research
Role of Genetic Risk in the Association Between Screen Time and Child Development —Reply
In Reply We appreciate the thoughtful comments on our study. We agree with Takahashi et al that the association between screen time and child development may be determined more accurately if genetic information is considered. Developmental delays may include neurodevelopmental disorders (autism spectrum disorder or attention-deficit/hyperactivity disorder) and other genetic characteristics. Recent studies have shown that diverse psychiatric disorders and behavioral traits, including neurodevelopmental disorders, share common genetic factors. Adjustments for genetic factors will be particularly important in identifying high...
Source: JAMA Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research
Role of Genetic Risk in the Association Between Screen Time and Child Development
To the Editor We recently published a study on data from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study that showed screen time for children aged 1 year was associated with developmental delays in communication and problem-solving skills domains at ages 2 and 4 years. We focused on the association and could not address whether long screen time is associated with developmental delay directionally or is a characteristic of children with developmental delay. Thus, we were curious about the direction of the association between screen time and child development. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research
Evaluation of a Large Language Model to Identify Confidential Content
This cross-sectional study assesses the ability of a language learning model to classify whether a progress note contains confidential information and to identify the specific confidential content in the note. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research
