Wildfire Smoke and Its Neurological Impact
This Viewpoint calls for a more concerted research effort aimed at establishing a robust link between wildfire smoke exposure and neurological effects. (Source: JAMA Neurology)
Source: JAMA Neurology - March 4, 2024 Category: Neurology Source Type: research

Current and Emerging Approaches to Coma Prognostication After Acute Brain Injury
This narrative review evaluates the current and emerging landscapes of prognostic markers of neurologic recovery from disorders of consciousness caused by severe, acute brain injury. (Source: JAMA Neurology)
Source: JAMA Neurology - March 4, 2024 Category: Neurology Source Type: research

Burden of Stroke Across the US From 1990 to 2019
This cross-sectional study investigates the stroke burden trends in the US in 2019 and how they evolved from 1990 to 2019 with a focus on age, sex, and region in the US. (Source: JAMA Neurology)
Source: JAMA Neurology - March 4, 2024 Category: Neurology Source Type: research

LDL-C Levels and Bleeding Risk in Patients Taking DAPT After Minor Ischemic Stroke or TIA
This cohort study investigates the association of low-density lipoprotein cholesterol (LDL-C) levels with bleeding risk in patients taking dual antiplatelet therapy (DAPT) after minor ischemic stroke or transient ischemic attack (TIA). (Source: JAMA Neurology)
Source: JAMA Neurology - March 4, 2024 Category: Neurology Source Type: research

Batoclimab vs Placebo for Generalized Myasthenia Gravis
This randomized clinical trial investigates the effectiveness and safety of the neonatal fragment crystallizable receptor monoclonal antibody, batoclimab, in adults with generalized myasthenia gravis. (Source: JAMA Neurology)
Source: JAMA Neurology - March 4, 2024 Category: Neurology Source Type: research

Male Carrier of X-Linked Adrenal Leukodystrophy Due to 47, XXY Karyotype
This case report studies a 12-year-old boy with a family history of X-linked adrenal leukodystrophy and his 8-year-old younger brother. (Source: JAMA Neurology)
Source: JAMA Neurology - March 4, 2024 Category: Neurology Source Type: research

JAMA Neurology
Mission Statement: The mission of JAMA Neurology is to publish and disseminate scientific information primarily important for physicians caring for people with neurologic disorders and for those interested in the structure and function of the normal and diseased human nervous system. The specific aims are to (1) publish timely original research, including clinical trials that will directly improve clinical neurologic care and that will inform efforts to improve neurological health and promote health care equity; (2) report translational research that is pertinent to the understanding of neurologic disease; (3) address topi...
Source: JAMA Neurology - March 1, 2024 Category: Neurology Source Type: research

Paused —a Residency Interrupted
This essay describes the author ’s experience with a biking accident. (Source: JAMA Neurology)
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research

Posttraumatic Epilepsy and Dementia Risk
This cohort study investigates associations of posttraumatic epilepsy with dementia risk. (Source: JAMA Neurology)
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research

Functional Outcomes in Conservatively vs Surgically Treated Cerebellar Infarcts
This cohort study evaluates functional outcomes in surgically compared with conservatively managed patients with cerebellar infarcts. (Source: JAMA Neurology)
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research

Patient Sex in Prescribing CGRP Receptor Antagonists for Migraine —Reply
In Reply We thank Lanteri-Minet et al for commenting on our recently published Viewpoint in JAMA Neurology addressing sex differences in outcomes of calcitonin gene-related peptide (CGRP) receptor antagonists in migraine treatment. As noted in their letter, our perspective was based on pooled pivotal trial data analysis obtained from published US Food and Drug Administration (FDA) reviews submitted by pharmaceutical sponsors that showed that there was no therapeutic gain in the male population for acute migraine treatment with either ubrogepant or rimegepant. We were pleased that the authors noted that our conclusions were...
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research

Patient Sex in Prescribing CGRP Receptor Antagonists for Migraine
To the Editor In a recent JAMA Neurology Viewpoint, Porreca and Dodick raised an important issue by discussing gender differences in outcomes of calcitonin gene-related peptide (CGRP) receptor antagonists in migraine treatment. Their point of view is supported by a pooled pivotal trial data analysis, which showed that there was no therapeutic gain seen in the male population for migraine short-term treatment with either ubrogepant or rimegepant. Their point of view is also supported by a body of experimental animal and human data showing that the involvement of CGRP is probably sexually dysmorphic. Such a sexual dysmorphis...
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research

Origin of Transthyretin in Cerebral Amyloid Angiopathy
This case series evaluates the correlation between transthyretin and cerebral amyloid angiopathy progression in individuals with hereditary transthyretin amyloidosis. (Source: JAMA Neurology)
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research

Errors in Figure 2 and the Short Title
This article has been corrected. (Source: JAMA Neurology)
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research

Error in Author Surname
This article was corrected online. (Source: JAMA Neurology)
Source: JAMA Neurology - February 26, 2024 Category: Neurology Source Type: research