JAMA Neurology —The Year in Review, 2022
Reflecting on the last 12 months here at JAMA Neurology, I am struck by just how much the journal continues to thrive, thanks in large part to all of you. While we continued to receive a number of high-quality submissions related to COVID-19, it felt more like prepandemic business as usual, as we published a wide-range of articles across a diverse set of neurologic disorders. I want to deeply thank all of the journal ’s editors, editorial board members, authors, and peer reviewers (who are listed elsewhere) for their tremendous contributions in 2022. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

Quantification of Penumbral Volume in Association With Time From Stroke Onset in Acute Ischemic Stroke
This cross-sectional study examines changes in the penumbral and core volumes over time to imaging in patients with acute ischemic stroke. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

Lecanemab and APOE Genotyping in Clinical Practice —Navigating Uncharted Terrain
This Viewpoint discusses the findings of the Clarity AD trial, which studied lecanemab for patients with early-stage Alzheimer disease. (Source: JAMA Neurology)
Source: JAMA Neurology - March 13, 2023 Category: Neurology Source Type: research

A Step Forward in the Fight Against Dementia
This Viewpoint reports on the results of the Clarity AD trial, a phase 3 randomized clinical trial of lecanemab for patients with early Alzheimer disease, in which lecanemab ’s clinical efficacy was demonstrated using well-established outcome measures. (Source: JAMA Neurology)
Source: JAMA Neurology - March 13, 2023 Category: Neurology Source Type: research

Physical Frailty, Genetic Predisposition, and Incident Parkinson Disease
This cohort study attempts to examine the longitudinal association of frailty phenotype with the development of Parkinson disease and to explore the modification role of genetic risk of Parkinson disease in such association. (Source: JAMA Neurology)
Source: JAMA Neurology - March 13, 2023 Category: Neurology Source Type: research