Focal Cortex Stimulation With a Novel Implantable Device and Antiseizure Outcomes
This pooled analysis of 2 nonrandomized uncontrolled trials investigates the association between epicranial electrical focal cortex simulation and seizure frequency in drug-refractory focal epilepsy. (Source: JAMA Neurology)
Source: JAMA Neurology - April 3, 2023 Category: Neurology Source Type: research

Association Between Use of Angiotensin Receptor Blockers and Incidence of Epilepsy in Patients With Hypertension —Reply
In Reply We are grateful to Ryu and Kuo for their interesting and important comments on our publication, “Association Between Angiotensin Receptor Blocker Therapy and Incidence of Epilepsy in Patients with Hypertension.” The authors addressed several points in their letter. (Source: JAMA Neurology)
Source: JAMA Neurology - April 3, 2023 Category: Neurology Source Type: research

Association Between Use of Angiotensin Receptor Blockers and Incidence of Epilepsy in Patients With Hypertension
To the Editor It is with great pleasure that we read the retrospective study by Doege et al, which found a reduced incidence of epilepsy in patients with hypertension receiving angiotensin receptor blockers (ARBs) compared with other antihypertensives. The risk was highest among patients receiving β-blockers and calcium channel blockers (CCBs). (Source: JAMA Neurology)
Source: JAMA Neurology - April 3, 2023 Category: Neurology Source Type: research

JAMA Neurology
Mission Statement: The mission of JAMA Neurology is to publish and disseminate scientific information primarily important for physicians caring for people with neurologic disorders and for those interested in the structure and function of the normal and diseased human nervous system. The specific aims are to (1) publish timely original research, including clinical trials that will directly improve clinical neurologic care and that will inform efforts to improve neurological health and promote health care equity; (2) report translational research that is pertinent to the understanding of neurologic disease; (3) address topi...
Source: JAMA Neurology - April 1, 2023 Category: Neurology Source Type: research

Kidney Dysfunction, Blood Biomarkers of Alzheimer Disease, and Phosphorylated Tau to Total Tau Ratios
This cross-sectional study investigates associations of chronic kidney disease with plasma ratios of phosphorylated tau 217 and 181 to the corresponding unphosphorylated peptides in Alzheimer disease. (Source: JAMA Neurology)
Source: JAMA Neurology - March 29, 2023 Category: Neurology Source Type: research

Hello, My Name is Doctor
This essay describes a physician ’s opinion of why using only a first name can be confusing rather than aiding in resolving inequalities between physicians and other hospital staff or patients. (Source: JAMA Neurology)
Source: JAMA Neurology - March 27, 2023 Category: Neurology Source Type: research

Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors
This cross-sectional study examines data from the UK Biobank to explore the association between focal epilepsy compared with stroke or migraine and the risk of developing dementia and how that risk is affected by modifiable cardiovascular risk factors. (Source: JAMA Neurology)
Source: JAMA Neurology - March 27, 2023 Category: Neurology Source Type: research

Error in Figure 3
This article was corrected online. (Source: JAMA Neurology)
Source: JAMA Neurology - March 27, 2023 Category: Neurology Source Type: research

JAMA Neurology Peer Reviewers in 2022
We sincerely thank the 749 peer reviewers who completed manuscript reviews for JAMA Neurology in 2022. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

Stroke, Death, and MI After Transcarotid Artery Revascularization vs Carotid Endarterectomy
This cohort study compares risk of 30-day stroke, death, or myocardial infarction or 1-year ipsilateral stroke among patients with standard surgical risk undergoing transcarotid artery revascularization vs carotid endarterectomy. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

Association Between Magnitude of Differential Blood Pressure Reduction and Secondary Stroke Prevention
This meta-analysis and meta-regression of randomized clinical trials evaluates the association of magnitude of differential blood pressure reduction and recurrent stroke in patients with stroke or transient ischemic attack. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

Transcarotid Artery Revascularization for Stroke Prevention —Multiple Elephants in the Room
In the saga of carotid revascularization procedures, carotid endarterectomy (CEA) has a track record of longer than 65 years. CEA has been shown in clinical trials to be useful for stroke prevention in select patients with symptomatic internal carotid artery stenosis and to a lesser extent, asymptomatic stenosis. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

JAMA Neurology —The Year in Review, 2022
Reflecting on the last 12 months here at JAMA Neurology, I am struck by just how much the journal continues to thrive, thanks in large part to all of you. While we continued to receive a number of high-quality submissions related to COVID-19, it felt more like prepandemic business as usual, as we published a wide-range of articles across a diverse set of neurologic disorders. I want to deeply thank all of the journal ’s editors, editorial board members, authors, and peer reviewers (who are listed elsewhere) for their tremendous contributions in 2022. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

Quantification of Penumbral Volume in Association With Time From Stroke Onset in Acute Ischemic Stroke
This cross-sectional study examines changes in the penumbral and core volumes over time to imaging in patients with acute ischemic stroke. (Source: JAMA Neurology)
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research

Lecanemab and APOE Genotyping in Clinical Practice —Navigating Uncharted Terrain
This Viewpoint discusses the findings of the Clarity AD trial, which studied lecanemab for patients with early-stage Alzheimer disease. (Source: JAMA Neurology)
Source: JAMA Neurology - March 13, 2023 Category: Neurology Source Type: research