Error in Abstract
This article was corrected online. (Source: JAMA Neurology)
Source: JAMA Neurology - September 1, 2023 Category: Neurology Source Type: research

Neuropathologic and Clinical Findings in Athletes With Repetitive Head Impacts
This cases series describes the neuropathologic and clinical features of young contact sport athletes who were younger than 30 years at the time of death. (Source: JAMA Neurology)
Source: JAMA Neurology - August 28, 2023 Category: Neurology Source Type: research

Suicide Rates Among Post-9/11 US Military Veterans With and Without Traumatic Brain Injury
This cohort study examines trends in suicide rates for veterans with and without traumatic brain injury compared with the US adult population. (Source: JAMA Neurology)
Source: JAMA Neurology - August 28, 2023 Category: Neurology Source Type: research

Teriflunomide and Time to Clinical Multiple Sclerosis in Radiologically Isolated Syndrome
This randomized clinical trial investigates the efficacy of the disease-modifying treatment, teriflunomide, in extending the time to a first clinical event in patients with preclinical multiple sclerosis. (Source: JAMA Neurology)
Source: JAMA Neurology - August 21, 2023 Category: Neurology Source Type: research

Effect of Bypassing the Closest Stroke Center in Patients with Intracerebral Hemorrhage
This prespecified secondary analysis of a randomized clinical trial conducted in Catalonia, Spain, assesses whether direct transport to an endovascular treatment –capable stroke center vs to the nearest local stroke center benefits patients experiencing intracerebral hemorrhage. (Source: JAMA Neurology)
Source: JAMA Neurology - August 21, 2023 Category: Neurology Source Type: research

Bypassing Closest Stroke Center for Intracerebral Hemorrhage
Prehospital stroke triage protocols focus on enabling rapid access to 2 proven time-sensitive short-term treatments: intravenous thrombolysis for all eligible patients with disabling acute ischemic stroke and endovascular therapy (EVT) for select patients with acute ischemic stroke from large vessel occlusion (LVO). As EVT is a particularly powerful treatment with an estimated number needed to treat of 2 to 3, prehospital screening tools and protocols have been developed that prioritize identifying potential patients with LVO in the field and preferentially transporting them to EVT-capable centers, even if this means bypas...
Source: JAMA Neurology - August 21, 2023 Category: Neurology Source Type: research

Error in Figures
This article was corrected online. (Source: JAMA Neurology)
Source: JAMA Neurology - August 21, 2023 Category: Neurology Source Type: research

JAMA Network Call for Papers on Health and the 2024 US Election
Nationally and globally, health will continue to be one of the most important policy issues for the 2024 US election. Information about these health issues is critical for decision-making and to answer pressing public and global health questions affecting the US and the world. US elections are not only domestic; they affect world politics, economies, security, welfare, and health. (Source: JAMA Neurology)
Source: JAMA Neurology - August 18, 2023 Category: Neurology Source Type: research

IPX203 vs Immediate-Release Carbidopa-Levodopa for the Treatment of Motor Fluctuations in Parkinson Disease
This randomized clinical trial evaluates the safety and efficacy of extended-release carbidopa-levodopa (IPX203) compared with immediate-release carbidopa-levodopa in patients with Parkinson disease. (Source: JAMA Neurology)
Source: JAMA Neurology - August 14, 2023 Category: Neurology Source Type: research

Increased Medial Temporal Tau Uptake Without Amyloid- β Positivity
This cohort study examines the pathologic and cognitive changes in older individuals with tau deposition in the medial temporal lobe noted on positron emission tomography without evidence of amyloid- β pathology. (Source: JAMA Neurology)
Source: JAMA Neurology - August 14, 2023 Category: Neurology Source Type: research

Alternate Hemibody Hyperkinetic and Hypokinetic Movement Disorders Due to Strategic Lesions in Cerebral Toxoplasmosis
This case report describes a women with a background of HIV presenting with complex involuntary movements with markedly different phenomenology on the right and left side of her body. (Source: JAMA Neurology)
Source: JAMA Neurology - August 14, 2023 Category: Neurology Source Type: research

Tau Pathology Without A β
Alzheimer disease (AD) is characterized by accumulation of amyloid- β (Aβ) plaques and tau neurofibrillary tangles that can be identified at autopsy or during life with fluid or imaging biomarkers. The presence of Aβ accumulation is an early event that precedes cognitive impairment by at least a decade and, based on the National Institute on Aging–Alzheimer’s Association Research Framework, defines whether an individual is on the AD pathway. The pathologic spread of tau aggregations throughout the brain appears to be triggered by Aβ, a sequence supported by the observation that abnormal tau, especially when present...
Source: JAMA Neurology - August 14, 2023 Category: Neurology Source Type: research

Full Court Press
This essay describes a care team and family rallying around a young girl facing what seem to be insurmountable odds. (Source: JAMA Neurology)
Source: JAMA Neurology - August 7, 2023 Category: Neurology Source Type: research

Hypothermia vs Normothermia on Societal Participation and Cognitive Function at 6 Months After OHCA
This study investigates the effects of targeted hypothermia vs targeted normothermia on functional outcome with focus on societal participation and cognitive function in survivors 6 months after out-of-hospital cardiac arrest. (Source: JAMA Neurology)
Source: JAMA Neurology - August 7, 2023 Category: Neurology Source Type: research

Myelin Oligodendrocyte Glycoprotein –IgA in a Subgroup of Patients With Central Nervous System Demyelination
This cross-sectional study examines laboratory and imaging data for patients with demyelinating central nervous system disease to investigate the frequency of MOG-IgA and associated clinical features. (Source: JAMA Neurology)
Source: JAMA Neurology - August 7, 2023 Category: Neurology Source Type: research