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What Clinicians Need to Know About TikTok
This Medical News article discusses research on health information being shared on the social media platform. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

How AI Is Helping to Restore Speech In Aphasia
In this Medical News article, Edward Chang, MD, chair of the department of neurological surgery at the University of California, San Francisco Weill Institute for Neurosciences joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the potential for AI to revolutionize communication for those unable to speak due to aphasia. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

Nerve Cell Growth Might Underlie Discomfort Tied to Recurrent UTIs
Recurrent urinary tract infections (UTIs) are defined as 2 positive urine cultures in the past 6 months, or 3 positive cultures within the past year. But even after taking antibiotics to treat recurrent UTIs, some patients continue experiencing pelvic pain and increased urgency to urinate, despite having urine cultures that test negative for bacteria. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

Antidepressant Prescriptions for Female Teens Surged After Pandemic
The rate of antidepressant prescriptions for teens and young adults increased by about two-thirds between 2016 and 2022, an analysis of information from a national database involving participants aged 12 to 25 years found. But the rate of increase wasn ’t constant, with prescriptions surging by about 64% per month after the start of the COVID-19 pandemic compared with a 17% increase per month before March 2020. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

COVID-19 Associated With Higher Risk of Autoimmune Diseases
People who were infected with SARS-CoV-2 had a 25% higher risk of later being diagnosed with an autoimmune inflammatory rheumatic disease (AIRD) after infection than those who weren ’t infected, according to a large cohort study that included more than 22 million participants in Japan and South Korea. They also had a 30% greater risk of developing AIRD, such as systemic lupus erythematosus or rheumatoid arthritis, compared with people who had influenza, the researchers report ed in the Annals of Internal Medicine. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

Meta-Analysis: Cardiovascular Risks Rose After Stopping Aspirin
Past recommendations suggested that patients with a high risk of cardiovascular problems might benefit from a daily low-dose aspirin when the advantages of preventing an initial cardiovascular event outweighed the harms associated with the chance of bleeding. The most up-to-date guidelines caution against starting aspirin treatment for primary prevention for most people, though. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

Therapy Delivered by Nonspecialists Improved Postpartum Mental Health
Women with anxiety who began receiving a cognitive behavioral therapy –based intervention from nonclinicians when they were less than 22 weeks pregnant experienced a major reduction in depression and anxiety 6 weeks after giving birth. Prenatal anxiety is associated with mental health disorders in postpartum parents. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

Study: Nearly 1 in 4 Families With Older Adults Has Food Insecurity
The proportion of US families that had at least 1 adult aged 60 years or older in the household and had food insecurity almost doubled over the past 2 decades, from roughly 12% to 23%, according to a recent cohort study involving about 3600 families. The researchers determined participants ’ level of food insecurity by asking them questions such as whether they were worried their food would run out before they had money to buy more, or if they had skipped any meals because they could not afford food. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

Ultraprocessed Foods Linked With 32 Types of Health Problems
Ultraprocessed foods include ready-to-eat meals, snacks, and sugary drinks that contain a long list of ingredients and additives designed to make the food sellable or palatable. Now these foods have been associated with more than 30 health conditions, a review of 45 meta-analyses involving about 9.9 million participants found. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

COVID-19 Infection Tied to Slight Cognitive Deficits
People who were infected with SARS-CoV-2 tended to score slightly worse on cognitive assessments —particularly in memory, reasoning, and tasks that require executive function—than those who were not infected, according to data from about 113 000 participants in England. The score was the equivalent of a 3-point loss on an IQ scale, the researchers reported in the New England Journal of Me dicine. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 22, 2024 Category: General Medicine Source Type: research

Quieting the Quiver
In this narrative medicine essay, a pediatric hospitalist identifies her sense of foreboding as a quiver that has and can rob her of moment-to-moment joy and in identifying it learns to use it as a guide to peace. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 21, 2024 Category: General Medicine Source Type: research

What Is Priapism?
This JAMA Patient Page describes the diagnosis, prevention, and treatment of priapism. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 21, 2024 Category: General Medicine Source Type: research

Vibration-Controlled Transient Elastography Scores and Liver-Related Events in Steatotic Liver Disease
This cohort study evaluates the prognostic implications of baseline and repeated vibration-controlled transient elastography scores and liver stiffness measurements in a large cohort of patients with Metabolic dysfunction-associated steatotic liver disease. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 21, 2024 Category: General Medicine Source Type: research

Sintilimab and Cardiovascular Toxicity —Reply
In Reply We thank Dr Peng and colleagues for their interest in the ORIENT-16 study and acknowledge their concerns about immune-related cardiotoxicities. All adverse events and their associations with treatment were carefully evaluated and reported per protocol. In Table 2 of the ORIENT-16 article, only common treatment-related adverse events (incidence of 15% or more, related to any drug) and immune-related adverse events (incidence of 2% or more) were listed in Table 2 of our article. Herein, we provide information about cardiotoxicity. Complete statistical tables are available upon request. (Source: JAMA - Journal of the...
Source: JAMA - Journal of the American Medical Association - March 21, 2024 Category: General Medicine Source Type: research

Sintilimab and Cardiovascular Toxicity
To the Editor A recent randomized clinical trial reported improved overall survival among patients receiving the combination of sintilimab with first-line chemotherapy compared with chemotherapy alone in unresectable gastric or gastroesophageal junction cancer. We are concerned that the ORIENT-16 trial did not report on the cardiovascular toxicity associated with immune checkpoint inhibitors, which can cause severe immune-related adverse events, including cardiovascular toxicity, which although rare can be fatal. However, a systematic review of 48 studies (11  207 patients) reported on 146 patients with cardiovascular to...
Source: JAMA - Journal of the American Medical Association - March 21, 2024 Category: General Medicine Source Type: research