Ominous Electrocardiogram Changes in a Man With Distal Extremity Weakness
This case report describes a man in his 30s who presented to the emergency department with a sudden onset of distal extremity weakness after waking up 10 hours prior. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 16, 2023 Category: Internal Medicine Source Type: research

Health Care Staff Turnover and Quality of Care at Nursing Homes
This cross-sectional study examines whether greater periods of nursing staff turnover are associated with quality of care in US nursing homes. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 9, 2023 Category: Internal Medicine Source Type: research

Causes of Vagally Mediated Paroxysmal Atrioventricular Block —Reply
In Reply It is an honor to be given the opportunity to respond to a letter from Dr Littmann. His insightful comments on our article made it more educational. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 9, 2023 Category: Internal Medicine Source Type: research

Causes of Vagally Mediated Paroxysmal Atrioventricular Block
To the Editor In a recent issue of JAMA Internal Medicine, Dr Zhou and colleagues presented an interesting and well-documented case of a patient whose Holter monitor revealed a 23.8-second ventricular asystole caused by paroxysmal atrioventricular block (PAVB). The authors convincingly demonstrated that the PAVB was the result of transient increase in parasympathetic tone rather than an intrinsic conduction system disease. However, the clinical cause of the vagally mediated PAVB and asystole was not explored or discussed. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 9, 2023 Category: Internal Medicine Source Type: research

Analysis of Devices Authorized by the FDA as Clinical Decision Support in Critical Care
This case series study examines the clinical evidence cited for US Food and Drug Administration –approved clinical decision support devices for use in the critical care setting. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 9, 2023 Category: Internal Medicine Source Type: research

FDA Regulations of AI-Driven Clinical Decision Support Devices Fall Short
We are entering a new era of computerized clinical decision support (CDS) tools. Companies are increasingly using artificial intelligence and/or machine learning (AI/ML) to develop new CDS devices, which are defined by the US Food and Drug Administration (FDA) as software used in disease prevention, diagnosis, or treatment. Recognizing the potential implications for clinical practice, the 21st Century Cures Act enjoined the FDA to regulate these new devices. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 9, 2023 Category: Internal Medicine Source Type: research

Errors in Supplement 1
This article has been corrected. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 9, 2023 Category: Internal Medicine Source Type: research

Diagnostic Challenges in Atrioventricular Block Preceding Cardiomyopathy
This case report describes a patient in their 30s with ventricular tachycardia and coexisting atrioventricular block and atrial fibrillation with normal cardiac structure and function. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 9, 2023 Category: Internal Medicine Source Type: research

Disparities in Kidney Transplant Waitlisting Among Young Patients
This cohort study examines disparities in kidney transplant waitlisting among younger patients without medical comorbidities in the US. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 2, 2023 Category: Internal Medicine Source Type: research

Feasibility of Emulating Trials Supporting Approvals of Drugs and Biologics
This cross-sectional study evaluates the supporting clinical trials for supplemental new drug applications and supplemental biologics license applications from 2017 to 2019. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 2, 2023 Category: Internal Medicine Source Type: research

Point-of-Care Ultrasonography in Suspected Acute Coronary Syndrome
This case report presents the ECG findings of a patient in their 40s with post-tubercular bronchiectasis who presented with acute exacerbation of dyspnea and no chest pain. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 2, 2023 Category: Internal Medicine Source Type: research

JAMA Internal Medicine
Mission Statement: To promote the art and science of medicine and the betterment of public health by publishing manuscripts of interest and relevance to internists practicing as generalists or as medical subspecialists. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - October 1, 2023 Category: Internal Medicine Source Type: research

Racial Disparities in Emergency Department Physical Restraint Use
This systematic review with meta-analysis examines the use of physical restraint use in adult emergency departments among patients of different racial and ethnic backgrounds. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - September 25, 2023 Category: Internal Medicine Source Type: research

Incidental CAC on Chest CT in Persons Without Known ASCVD
This cross-sectional study examines the expected prevalence of coronary artery calcium (CAC) on chest computed tomography (CT) in people without clinical atherosclerotic cardiovascular disease (ASCVD) by age, sex, and race and ethnicity. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - September 25, 2023 Category: Internal Medicine Source Type: research

Coronary Artery Calcium Screening —Data First
Screening tests are examinations performed on asymptomatic individuals to diagnose life-threatening medical conditions early enough to intervene to reduce disease-specific and overall mortality. Although the benefits of finding an unrecognized disease early in its course seem intuitive, screening tests and the clinical decisions based on them require testing with randomized clinical trials (RCTs) to understand the magnitude of benefit (if any) and the potential for harms including radiation, psychological stress, and unnecessary downstream testing and treatment with additional costs and potential complications. Coronary ar...
Source: JAMA Internal Medicine - September 25, 2023 Category: Internal Medicine Source Type: research