JAHA:Journal of the American Heart Association This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Prediction of Cardiovascular Disease by the Framingham-REGICOR Equation in the High-Risk PREDIMED Cohort: Impact of the Mediterranean Diet Across Different Risk Strata [Epidemiology]
ConclusionsIncident CVD increased in parallel with estimated risk in the PREDIMED cohort, but most events occurred in non–high‐risk categories, particularly in women. Until predictive tools are improved, promotion of the Mediterranean diet might be useful to reduce CVD independent of baseline risk.Clinical Trial Registration URL: http://www.Controlled-trials.com. Unique identifier: ISRCTN35739639. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Amor, A. J., Serra-Mir, M., Martinez-Gonzalez, M. A., Corella, D., Salas-Salvado, J., Fito, M., Estruch, R., Serra-Maȷem, L., Aros, F., Babio, N., Ros, E., Ortega, E., the PREDIMED Investigators Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Lifestyle, Primary Prevention Original Research Source Type: research

Risk of Inhospital Stroke or Death Is Associated With Age But Not Sex in Patients Treated With Carotid Endarterectomy for Asymptomatic or Symptomatic Stenosis in Routine Practice: Secondary Data Analysis of the Nationwide German Statutory Quality Assurance Database From 2009 to 2014 [Cardiovascular Surgery]
ConclusionsThis study shows that increasing age, but not sex, is associated with a higher risk of in‐hospital stroke or death following carotid endarterectomy under everyday conditions in Germany. Whereas the risk of death (alone) is significantly associated with age, the association between age and the risk of stroke (alone) can be considered of minor importance. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Schmid, S., Tsantilas, P., Knappich, C., Kallmayer, M., Konig, T., Breitkreuz, T., Zimmermann, A., Kuehnl, A., Eckstein, H.–H. Tags: Aging, Women, Cardiovascular Surgery, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Research Source Type: research

Activation of CD137 Signaling Promotes Angiogenesis in Atherosclerosis via Modulating Endothelial Smad1/5-NFATc1 Pathway [Vascular Medicine]
ConclusionsThese findings suggest that CD137 signaling is a new regulator of angiogenesis by modulating the Smad1/5‐NFATc1 pathway. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Weng, J., Wang, C., Zhong, W., Li, B., Wang, Z., Shao, C., Chen, Y., Yan, J. Tags: Angiogenesis, Animal Models of Human Disease, Inflammation, Atherosclerosis, Vascular Disease Original Research Source Type: research

Lay Bystanders' Perspectives on What Facilitates Cardiopulmonary Resuscitation and Use of Automated External Defibrillators in Real Cardiac Arrests [Resuscitation Science]
ConclusionsSeveral factors other than previous hands‐on CPR training facilitate lay bystander instigation of CPR and AED use. The recognition and modification of these factors may increase lay bystander CPR rates and patient survival following an out‐of‐hospital cardiac arrest. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Malta Hansen, C., Rosenkranz, S. M., Folke, F., Zinckernagel, L., Tȷornhoȷ-Thomsen, T., Torp-Pedersen, C., Sondergaard, K. B., Nichol, G., Hulveȷ Rod, M. Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Cardiopulmonary Arrest Original Research Source Type: research

China Stroke Primary Prevention Trial: Visit-to-Visit Systolic Blood Pressure Variability Is an Independent Predictor of Primary Stroke in Hypertensive Patients [Stroke]
ConclusionsVisit‐to‐visit SBP variability is an independent predictor of primary stroke in Chinese hypertensive patients. This predictive value depends on the number of blood pressure measurements used to calculate variability but is independent of mean SBP.Clinical Trial RegistrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT00794885. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Men, X., Sun, W., Fan, F., Zhao, M., Huang, X., Wang, Y., Liu, L., Liu, R., , Peng, Q., Qin, X., Tang, G., Li, J., Zhang, Y., Cai, Y., Hou, F. F., Wang, B., Xu, X., Cheng, X., Sun, N., Huang, Y., Huo, Y. Tags: Epidemiology, Hypertension, Cerebrovascular Disease/Stroke Original Research Source Type: research

Bone Mineral Density and Risk of Heart Failure in Older Adults: The Cardiovascular Health Study [Heart Failure]
ConclusionsAmong older adults, lower total hip BMD was associated with higher HF risk in nonblack men but lower risk in black men, with no evidence of an association in women. Further research is needed to replicate these findings and to study potential underlying pathways. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Fohtung, R. B., Brown, D. L., Koh, W. J. H., Bartz, T. M., Carbone, L. D., Civitelli, R., Stein, P. K., Chaves, P. H. M., Kestenbaum, B. R., Kizer, J. R. Tags: Heart Failure Original Research Source Type: research

Atrial Arrhythmias and Electroanatomical Remodeling in Patients With Left Ventricular Assist Devices [Arrhythmia and Electrophysiology]
BackgroundThe incidence, predictors, and impact of atrial arrhythmias along with left atrial structural changes in patients with left ventricular assist devices (LVADs) remain undetermined.Methods and ResultsAll patients who underwent LVAD implantation from 2008 to 2015 at the University of Chicago Medical Center were included. Electronic medical records, electrocardiograms, echocardiograms, and cardiac electrical device interrogations were reviewed. The association of arrhythmias and clinical covariates with survival was evaluated by Kaplan–Meier and Cox proportional hazards analyses. A total of 331 patients were follow...
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Deshmukh, A., Kim, G., Burke, M., Anyanwu, E., Jeevanandam, V., Uriel, N., Tung, R., Ozcan, C. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Heart Failure, Remodeling Original Research Source Type: research

CCR7-CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia [Health Services and Outcomes Research]
ConclusionsThese data show that CCR7‐CCL19/CCL21 axis facilitates retention CD4+ T lymphocytes at the site of collateral artery remodeling, which is essential for effective arteriogenesis. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Nossent, A. Y., Bastiaansen, A. J. N. M., Peters, E. A. B., de Vries, M. R., Aref, Z., Welten, S. M. J., de Jager, S. C. A., van der Pouw Kraan, T. C. T. M., Quax, P. H. A. Tags: Angiogenesis, Peripheral Vascular Disease Original Research Source Type: research

Impact of Achieved Blood Pressure on First Stroke in Uncomplicated Grade 1 Hypertension [Cardiovascular Surgery]
BackgroundWe aimed to test the impact of achieved blood pressure (BP) on first stroke among patients with grade 1 hypertension and without cardiovascular diseases in the China Stroke Primary Prevention Trial.Methods and ResultsA total of 3187 patients with uncomplicated grade 1 hypertension were included. The risk of outcomes was assessed according to: (1) the proportion of visits in which BP was reduced to (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Qin, X., Li, Y., Sun, N., He, M., Tang, G., Yin, D., Wang, J., Liang, M., Wang, B., Huo, Y., Xu, X., , Hou, F. F. Tags: Primary Prevention, High Blood Pressure, Cerebrovascular Disease/Stroke Original Research Source Type: research

Cardioversion Efficacy Using Pulsed Biphasic or Biphasic Truncated Exponential Waveforms: A Randomized Clinical Trial [Arrhythmia and Electrophysiology]
ConclusionsCardioversion using a BTE waveform was more effective when compared with a PB waveform. There was no difference in safety between the 2 waveforms, as judged by changes in troponin I levels.Clinical Trial RegistrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT02317029. (Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Schmidt, A. S., Lauridsen, K. G., Adelborg, K., Torp, P., Bach, L. F., Jepsen, S. M., Hornung, N., Deakin, C. D., Rickers, H., Lofgren, B. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Original Research Source Type: research

Deferred Versus Immediate Stenting in Patients With ST–Segment Elevation Myocardial Infarction: A Systematic Review and Meta–Analysis [Systematic Review and Meta-Analysis]
BackgroundA number of studies have evaluated the efficacy of deferred stenting vs immediate stenting in patients with ST‐segment elevation myocardial infarction, but the findings were not consistent across these studies. This meta‐analysis aims to assess optimal treatment strategies in patient with ST‐segment elevation myocardial infarction.Methods and ResultsWe searched the PubMed, EMBASE, and the Cochrane Library for studies that assessed deferred vs immediate stenting in patients with ST‐segment elevation myocardial infarction. Nine studies including 1456 patients in randomized controlled trials and 719 patients...
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Qiao, J., Pan, L., Zhang, B., Wang, J., Zhao, Y., Yang, R., Du, H., Jiang, J., Jin, C., Xiong, E. Tags: Percutaneous Coronary Intervention Systematic Review and Meta ‐ Analysis Source Type: research

Relations of Metabolically Healthy and Unhealthy Obesity to Digital Vascular Function in Three Community–Based Cohorts: A Meta–Analysis [Systematic Review and Meta-Analysis]
BackgroundMicrovascular dysfunction is a marker of early vascular disease that predicts cardiovascular events. Whether metabolically healthy obese individuals have impaired microvascular function remains unclear. The aim of this study was to evaluate the relation of obesity phenotypes stratified by metabolic status to microvascular function.Methods and ResultsWe meta‐analyzed aggregate data from 3 large cohorts (Brazilian Longitudinal Study of Adult Health, the Framingham Heart Study, and the Gutenberg Heart Study; n=16 830 participants, age range 19–90, 51.3% men). Regression slopes between cardiovascular risk factor...
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Brant, L. C. C., Wang, N., Oȷeda, F. M., LaValley, M., Barreto, S. M., Benȷamin, E. J., Mitchell, G. F., Vasan, R. S., Palmisano, J. N., Munzel, T., Blankenberg, S., Wild, P. S., Zeller, T., Ribeiro, A. L. P., Schnabel, R. B., Hamburg, N. M. Tags: Endothelium/Vascular Type/Nitric Oxide, Epidemiology, Obesity, Risk Factors, Vascular Disease Systematic Review and Meta ‐ Analysis Source Type: research

Left Ventricular Hypertrophy Regression During Antihypertensive Treatment in an Outpatient Clinic (the Campania Salute Network) [Hypertension]
This study tests the external validity of results of clinical trials on LVH regression using a large registry from a tertiary care center, to identify phenotypes less likely to achieve regression of LVH.Methods and ResultsPatients from the Campania Salute Network, free of prevalent cardiovascular disease, but with echocardiographic LVH (defined as LV mass index [LVMi]>47 g/m2.7 in women and>50 g/m2.7 in men) were included. During a median follow‐up of 67 months, clear‐cut regression of LVH was documented in 14% of patients (13±8% reduction of initial LVMi) or 23% when also considering those with a reduction of LVMi...
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Lonnebakken, M. T., Izzo, R., Mancusi, C., Gerdts, E., Losi, M. A., Canciello, G., Giugliano, G., De Luca, N., Trimarco, B., de Simone, G. Tags: Hypertension Original Research Source Type: research

Obesity Increases Risk-Adȷusted Morbidity, Mortality, and Cost Following Cardiac Surgery [Cardiovascular Surgery]
BackgroundDespite the epidemic rise in obesity, few studies have evaluated the effect of obesity on cost following cardiac surgery. We hypothesized that increasing body mass index (BMI) is associated with worse risk‐adjusted outcomes and higher cost.Methods and ResultsMedical records for 13 637 consecutive patients who underwent coronary artery bypass grafting (9702), aortic (1535) or mitral (837) valve surgery, and combined valve–coronary artery bypass grafting (1663) procedures were extracted from a regional Society of Thoracic Surgeons certified database. Patients were stratified by BMI: normal to overweight (BMI 1...
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Ghanta, R. K., LaPar, D. J., Zhang, Q., Devarkonda, V., Isbell, J. M., Yarboro, L. T., Kern, J. A., Kron, I. L., Speir, A. M., Fonner, C. E., Ailawadi, G. Tags: Obesity, Cardiovascular Surgery, Cost-Effectiveness, Quality and Outcomes Original Research Source Type: research

Gastrointestinal-Renal Axis: Role in the Regulation of Blood Pressure [Contemporary Review]
(Source: JAHA:Journal of the American Heart Association)
Source: JAHA:Journal of the American Heart Association - March 6, 2017 Category: Cardiology Authors: Yang, J., Jose, P. A., Zeng, C. Tags: High Blood Pressure, Hypertension Contemporary Review Source Type: research