The differences and overlaps between 'explanatory' and 'pragmatic' controlled trials: a historical perspective
J R Soc Med. 2023 Nov 22:1410768231207536. doi: 10.1177/01410768231207536. Online ahead of print.NO ABSTRACTPMID:37991449 | DOI:10.1177/01410768231207536 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 22, 2023 Category: General Medicine Authors: Paul Glasziou Robert Matthews Isabelle Boutron Iain Chalmers Peter Armitage Source Type: research
Paul Owren, Christopher Bjerkelund and the dawn of controlled trials in Norway
J R Soc Med. 2023 Nov 22:1410768231207292. doi: 10.1177/01410768231207292. Online ahead of print.NO ABSTRACTPMID:37991459 | DOI:10.1177/01410768231207292 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 22, 2023 Category: General Medicine Authors: Magne Nylenna Source Type: research
Heresy, witchcraft, Jean Gerson, scepticism and the use of placebo controls
J R Soc Med. 2023 Nov 22:1410768231207260. doi: 10.1177/01410768231207260. Online ahead of print.NO ABSTRACTPMID:37991475 | DOI:10.1177/01410768231207260 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 22, 2023 Category: General Medicine Authors: R Kirakosian L M öllenbrink G Zamore T J Kaptchuk K Jensen Source Type: research
A deathly silence: why has the number of people found decomposed in England and Wales been rising?
CONCLUSIONS: The increase in people found dead from unknown causes suggests wider societal breakdowns of both formal and informal social support networks. They are concerning and warrant urgent further investigation. We call on national and international authorities to consider measures that would make it possible to identify these deaths more easily in routine data.PMID:37989250 | DOI:10.1177/01410768231209001 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 21, 2023 Category: General Medicine Authors: Lucinda Hiam Theodore Estrin-Serlui Danny Dorling Martin McKee Jon Minton Source Type: research
A deathly silence: why has the number of people found decomposed in England and Wales been rising?
CONCLUSIONS: The increase in people found dead from unknown causes suggests wider societal breakdowns of both formal and informal social support networks. They are concerning and warrant urgent further investigation. We call on national and international authorities to consider measures that would make it possible to identify these deaths more easily in routine data.PMID:37989250 | DOI:10.1177/01410768231209001 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 21, 2023 Category: General Medicine Authors: Lucinda Hiam Theodore Estrin-Serlui Danny Dorling Martin McKee Jon Minton Source Type: research
Trial analysis by treatment allocated or by treatment received? Origins of 'the intention-to-treat principle' to reduce allocation bias: part 2
J R Soc Med. 2023 Nov 17:1410768231203936. doi: 10.1177/01410768231203936. Online ahead of print.NO ABSTRACTPMID:37975723 | DOI:10.1177/01410768231203936 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 17, 2023 Category: General Medicine Authors: I Chalmers R Matthews P Glasziou I Boutron P Armitage Source Type: research
Trial analysis by treatment allocated or by treatment received? Origins of 'the intention-to-treat principle' to reduce allocation bias: part 2
J R Soc Med. 2023 Nov 17:1410768231203936. doi: 10.1177/01410768231203936. Online ahead of print.NO ABSTRACTPMID:37975723 | DOI:10.1177/01410768231203936 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 17, 2023 Category: General Medicine Authors: I Chalmers R Matthews P Glasziou I Boutron P Armitage Source Type: research
Trial analysis by treatment allocated or by treatment received? Origins of 'the intention-to-treat principle' to reduce allocation bias: part 2
J R Soc Med. 2023 Nov 17:1410768231203936. doi: 10.1177/01410768231203936. Online ahead of print.NO ABSTRACTPMID:37975723 | DOI:10.1177/01410768231203936 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 17, 2023 Category: General Medicine Authors: I Chalmers R Matthews P Glasziou I Boutron P Armitage Source Type: research
The difference in all-cause mortality between COVID-19 patients treated with standard of care plus placebo and those treated with standard of care alone: a network meta-analysis of randomised controlled trials of immunomodulatory kinase inhibitors
CONCLUSIONS: This NMA suggested a higher all-cause mortality in patients treated with placebo plus SoC compared with those treated with SoC alone. However, caution is advised in interpreting these results due to the absence of a direct head-to-head comparison. Future research should critically evaluate the necessity of placebo administration in COVID-19 RCTs and consider alternative study designs to minimise potential biases.Trial registration: The current study was approved by the Institutional Review Board of the Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan (TSGHIRB No. B-109-29) and regi...
Source: J R Soc Med AND (has... - November 16, 2023 Category: General Medicine Authors: Ping-Tao Tseng Bing-Syuan Zeng Chih-Wei Hsu Trevor Thompson Brendon Stubbs Po-Ren Hsueh Kuan-Pin Su Yen-Wen Chen Tien-Yu Chen Yi-Cheng Wu Pao-Yen Lin Andre F Carvalho Dian-Jeng Li Ta-Chuan Yeh Cheuk-Kwan Sun Yu-Shian Cheng Yow-Ling Shiue Chih-Sung Liang Y Source Type: research
Trial analysis by treatment allocated or by treatment received? Origins of 'the intention-to-treat principle' to reduce allocation bias: Part 1
J R Soc Med. 2023 Oct;116(10):343-350. doi: 10.1177/01410768231203922.NO ABSTRACTPMID:37961883 | DOI:10.1177/01410768231203922 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 14, 2023 Category: General Medicine Authors: I Chalmers R Matthews P Glasziou I Boutron P Armitage Source Type: research
Rigour and science in drug regulatory approval
J R Soc Med. 2023 Oct;116(10):323. doi: 10.1177/01410768231211565.NO ABSTRACTPMID:37961884 | DOI:10.1177/01410768231211565 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 14, 2023 Category: General Medicine Authors: Kamran Abbasi Source Type: research
Trial analysis by treatment allocated or by treatment received? Origins of 'the intention-to-treat principle' to reduce allocation bias: Part 1
J R Soc Med. 2023 Oct;116(10):343-350. doi: 10.1177/01410768231203922.NO ABSTRACTPMID:37961883 | DOI:10.1177/01410768231203922 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 14, 2023 Category: General Medicine Authors: I Chalmers R Matthews P Glasziou I Boutron P Armitage Source Type: research
Rigour and science in drug regulatory approval
J R Soc Med. 2023 Oct;116(10):323. doi: 10.1177/01410768231211565.NO ABSTRACTPMID:37961884 | DOI:10.1177/01410768231211565 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 14, 2023 Category: General Medicine Authors: Kamran Abbasi Source Type: research
Death Notices
J R Soc Med. 2023 Oct;116(10):355. doi: 10.1177/01410768231211791.NO ABSTRACTPMID:37961880 | DOI:10.1177/01410768231211791 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 14, 2023 Category: General Medicine Source Type: research
From < em > JRSM Open < /em >
J R Soc Med. 2023 Oct;116(10):355. doi: 10.1177/01410768231212719.NO ABSTRACTPMID:37961881 | DOI:10.1177/01410768231212719 (Source: J R Soc Med AND (has...)
Source: J R Soc Med AND (has... - November 14, 2023 Category: General Medicine Source Type: research
