Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research

Traditional Chinese medicine for treating aplastic anemia
This article reviews the potential mechanism of traditional Chinese medicine or its active ingredients in the treatment of AA. These include improving the bone marrow microenvironment, regulating immunity, and affecting the fate of hematopoietic stem cells. This provides useful information for further treatment of AA with integration of traditional Chinese and Western medicine and the development of new treatment strategies.PMID:38022904 | PMC:PMC10679336 | DOI:10.3389/jpps.2023.11863 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Jing Guan YiHui Zhao Ting Wang Rong Fu Source Type: research

Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research

Traditional Chinese medicine for treating aplastic anemia
This article reviews the potential mechanism of traditional Chinese medicine or its active ingredients in the treatment of AA. These include improving the bone marrow microenvironment, regulating immunity, and affecting the fate of hematopoietic stem cells. This provides useful information for further treatment of AA with integration of traditional Chinese and Western medicine and the development of new treatment strategies.PMID:38022904 | PMC:PMC10679336 | DOI:10.3389/jpps.2023.11863 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Jing Guan YiHui Zhao Ting Wang Rong Fu Source Type: research

Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research

Traditional Chinese medicine for treating aplastic anemia
This article reviews the potential mechanism of traditional Chinese medicine or its active ingredients in the treatment of AA. These include improving the bone marrow microenvironment, regulating immunity, and affecting the fate of hematopoietic stem cells. This provides useful information for further treatment of AA with integration of traditional Chinese and Western medicine and the development of new treatment strategies.PMID:38022904 | PMC:PMC10679336 | DOI:10.3389/jpps.2023.11863 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Jing Guan YiHui Zhao Ting Wang Rong Fu Source Type: research

Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research

Traditional Chinese medicine for treating aplastic anemia
This article reviews the potential mechanism of traditional Chinese medicine or its active ingredients in the treatment of AA. These include improving the bone marrow microenvironment, regulating immunity, and affecting the fate of hematopoietic stem cells. This provides useful information for further treatment of AA with integration of traditional Chinese and Western medicine and the development of new treatment strategies.PMID:38022904 | PMC:PMC10679336 | DOI:10.3389/jpps.2023.11863 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Jing Guan YiHui Zhao Ting Wang Rong Fu Source Type: research

Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research

Traditional Chinese medicine for treating aplastic anemia
This article reviews the potential mechanism of traditional Chinese medicine or its active ingredients in the treatment of AA. These include improving the bone marrow microenvironment, regulating immunity, and affecting the fate of hematopoietic stem cells. This provides useful information for further treatment of AA with integration of traditional Chinese and Western medicine and the development of new treatment strategies.PMID:38022904 | PMC:PMC10679336 | DOI:10.3389/jpps.2023.11863 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Jing Guan YiHui Zhao Ting Wang Rong Fu Source Type: research

Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research

Traditional Chinese medicine for treating aplastic anemia
This article reviews the potential mechanism of traditional Chinese medicine or its active ingredients in the treatment of AA. These include improving the bone marrow microenvironment, regulating immunity, and affecting the fate of hematopoietic stem cells. This provides useful information for further treatment of AA with integration of traditional Chinese and Western medicine and the development of new treatment strategies.PMID:38022904 | PMC:PMC10679336 | DOI:10.3389/jpps.2023.11863 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Jing Guan YiHui Zhao Ting Wang Rong Fu Source Type: research

Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research

Traditional Chinese medicine for treating aplastic anemia
This article reviews the potential mechanism of traditional Chinese medicine or its active ingredients in the treatment of AA. These include improving the bone marrow microenvironment, regulating immunity, and affecting the fate of hematopoietic stem cells. This provides useful information for further treatment of AA with integration of traditional Chinese and Western medicine and the development of new treatment strategies.PMID:38022904 | PMC:PMC10679336 | DOI:10.3389/jpps.2023.11863 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Jing Guan YiHui Zhao Ting Wang Rong Fu Source Type: research

Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches
J Pharm Pharm Sci. 2023 Nov 7;26:11808. doi: 10.3389/jpps.2023.11808. eCollection 2023.ABSTRACTLong-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure, portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy available for liver fibrosis. Thus, continuous investigations for anti-fibrotic therapy are ongoing. The main theme of anti-fibrotic investigation during recent years is the rationale-based selection of treatment molecules according to the current understanding of the pathology of the disease. The research efforts are mainly toward repurposin...
Source: J Pharm Pharm Sci - November 29, 2023 Category: Drugs & Pharmacology Authors: Omima S Mohammed Hany G Attia Bassim M S A Mohamed Marawan A Elbaset Hany M Fayed Source Type: research