Patisiran, an RNAi therapeutic for hereditary transthyretin-mediated amyloidosis: Sub-analysis in Taiwanese patients from the APOLLO study
CONCLUSIONS: This analysis suggests that patisiran is well tolerated and may provide a substantial clinical benefit for Taiwanese patients with hATTR amyloidosis with polyneuropathy.TRIAL REGISTRATION INFORMATION: The studies were registered on the ClinicalTrials.gov. The APOLLO study ClinicalTrials.gov identifier is NCT01960348 (https://clinicaltrials.gov/ct2/show/NCT01960348), with the registration date of October 10, 2013, and the first patient was enrolled on December 13, 2013. For the global OLE, the ClinicalTrials.gov identifier is NCT02510261 (https://clinicaltrials.gov/ct2/show/NCT02510261) with the registration da...
Source: J Formos Med Assoc - March 28, 2024 Category: General Medicine Authors: Kon-Ping Lin Chih-Chao Yang Yi-Chung Lee Ming-Jen Lee John Vest Marianne T Sweetser Matthew T White Prajakta Badri Sung-Tsang Hsieh Chi-Chao Chao Source Type: research
Impacts of COVID-19 pandemic on the collection and use of blood and blood components in Taiwan
This study aims to evaluate changes in blood collection and transfusions during the period following the nationwide Level 3 alert (May-July 2021).METHODS: We retrieved usage data for red blood cells (RBC) from the Taiwan National Health Insurance (NHI) database 2019-2021.RESULTS: During the Level 3 alert period, approximately 85% of COVID-19 cases (11,455/13,624) were in Taipei. In Taipei, blood collection declined by 26.34% and RBC transfusions decreased by 17.14% compared to pre-pandemic levels. RBC usage decreased across all service types, with a significant decrease observed in hematology/oncology by 15.62% (-483 patie...
Source: J Formos Med Assoc - March 28, 2024 Category: General Medicine Authors: Ling-I Hsu Jen-Wei Chen Sheng-Tang Wei Sheng-Mou Hou Source Type: research
Patisiran, an RNAi therapeutic for hereditary transthyretin-mediated amyloidosis: Sub-analysis in Taiwanese patients from the APOLLO study
CONCLUSIONS: This analysis suggests that patisiran is well tolerated and may provide a substantial clinical benefit for Taiwanese patients with hATTR amyloidosis with polyneuropathy.TRIAL REGISTRATION INFORMATION: The studies were registered on the ClinicalTrials.gov. The APOLLO study ClinicalTrials.gov identifier is NCT01960348 (https://clinicaltrials.gov/ct2/show/NCT01960348), with the registration date of October 10, 2013, and the first patient was enrolled on December 13, 2013. For the global OLE, the ClinicalTrials.gov identifier is NCT02510261 (https://clinicaltrials.gov/ct2/show/NCT02510261) with the registration da...
Source: J Formos Med Assoc - March 28, 2024 Category: General Medicine Authors: Kon-Ping Lin Chih-Chao Yang Yi-Chung Lee Ming-Jen Lee John Vest Marianne T Sweetser Matthew T White Prajakta Badri Sung-Tsang Hsieh Chi-Chao Chao Source Type: research
Impacts of COVID-19 pandemic on the collection and use of blood and blood components in Taiwan
This study aims to evaluate changes in blood collection and transfusions during the period following the nationwide Level 3 alert (May-July 2021).METHODS: We retrieved usage data for red blood cells (RBC) from the Taiwan National Health Insurance (NHI) database 2019-2021.RESULTS: During the Level 3 alert period, approximately 85% of COVID-19 cases (11,455/13,624) were in Taipei. In Taipei, blood collection declined by 26.34% and RBC transfusions decreased by 17.14% compared to pre-pandemic levels. RBC usage decreased across all service types, with a significant decrease observed in hematology/oncology by 15.62% (-483 patie...
Source: J Formos Med Assoc - March 28, 2024 Category: General Medicine Authors: Ling-I Hsu Jen-Wei Chen Sheng-Tang Wei Sheng-Mou Hou Source Type: research
Modified screening and management strategies for chronic rhinosinusitis in hematologic patients receiving hematopoietic stem cell transplantation
CONCLUSIONS: Sinonasal evaluation should be targeted to the high-risk group. ESS is effective in managing CRS, while control of CRS is not determinant of overall survival in patients receiving HSCT.PMID:38531697 | DOI:10.1016/j.jfma.2024.03.013 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 26, 2024 Category: General Medicine Authors: Yen-Hui Lee Chih-Feng Lin Te-Huei Yeh Huai-Hsuan Huang Yi-Tsen Lin Source Type: research
Responses to comments on "impact of post-implantation time on bioresorbable vascular scaffold outcomes for type C versus non-type C coronary lesions: A longer-term study"
J Formos Med Assoc. 2024 Mar 25:S0929-6646(24)00171-2. doi: 10.1016/j.jfma.2024.03.010. Online ahead of print.NO ABSTRACTPMID:38531698 | DOI:10.1016/j.jfma.2024.03.010 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 26, 2024 Category: General Medicine Authors: Yi-Chih Wang Source Type: research
Modified screening and management strategies for chronic rhinosinusitis in hematologic patients receiving hematopoietic stem cell transplantation
CONCLUSIONS: Sinonasal evaluation should be targeted to the high-risk group. ESS is effective in managing CRS, while control of CRS is not determinant of overall survival in patients receiving HSCT.PMID:38531697 | DOI:10.1016/j.jfma.2024.03.013 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 26, 2024 Category: General Medicine Authors: Yen-Hui Lee Chih-Feng Lin Te-Huei Yeh Huai-Hsuan Huang Yi-Tsen Lin Source Type: research
Responses to comments on "impact of post-implantation time on bioresorbable vascular scaffold outcomes for type C versus non-type C coronary lesions: A longer-term study"
J Formos Med Assoc. 2024 Mar 25:S0929-6646(24)00171-2. doi: 10.1016/j.jfma.2024.03.010. Online ahead of print.NO ABSTRACTPMID:38531698 | DOI:10.1016/j.jfma.2024.03.010 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 26, 2024 Category: General Medicine Authors: Yi-Chih Wang Source Type: research
End-stage renal disease should not Be considered a contraindication for veno-arterial extracorporeal membrane oxygenation
CONCLUSIONS: ESRD was not an independent predictor of in-hospital mortality after VA-ECMO. The survival of ESRD patients was not inferior to those without ESRD when receiving ECPR. Therefore, ESRD should not be considered a contraindication to VA-ECMO in adults.PMID:38527921 | DOI:10.1016/j.jfma.2024.03.012 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 25, 2024 Category: General Medicine Authors: Chen-Hsu Pai Chi-Ling Chen Chih-Hsien Wang Nai-Hsin Chi Shu-Chien Huang Li-Jung Tseng Chien-Heng Lai Hsi-Yu Yu Nai-Kuan Chou Ron-Bin Hsu Yih-Sharng Chen Source Type: research
End-stage renal disease should not Be considered a contraindication for veno-arterial extracorporeal membrane oxygenation
CONCLUSIONS: ESRD was not an independent predictor of in-hospital mortality after VA-ECMO. The survival of ESRD patients was not inferior to those without ESRD when receiving ECPR. Therefore, ESRD should not be considered a contraindication to VA-ECMO in adults.PMID:38527921 | DOI:10.1016/j.jfma.2024.03.012 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 25, 2024 Category: General Medicine Authors: Chen-Hsu Pai Chi-Ling Chen Chih-Hsien Wang Nai-Hsin Chi Shu-Chien Huang Li-Jung Tseng Chien-Heng Lai Hsi-Yu Yu Nai-Kuan Chou Ron-Bin Hsu Yih-Sharng Chen Source Type: research
Sequential multimodal treatments with chemotherapy and surgery for advanced soft tissue sarcoma may be associated with better survival than chemotherapy
CONCLUSION: Surgery may be more beneficial for the patients who receive chemotherapy. Our results support evaluation of sequential multimodal treatments strategy including surgery and chemotherapy in patients with advanced STS.PMID:38521760 | DOI:10.1016/j.jfma.2024.03.007 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 23, 2024 Category: General Medicine Authors: Ching-Tso Chen Hsing-Wu Chen Wei-Hsin Lin Pei-Ming Huang Mong-Wei Lin Ching-Yao Yang Che-Yu Hsu Chia-Chun Wang Jen-Chieh Lee Koping Chang Kuo-Hao Huang Ho-Min Chen Tom Wei-Wu Chen Rong-Sen Yang Ruey-Long Hong Source Type: research
Sequential multimodal treatments with chemotherapy and surgery for advanced soft tissue sarcoma may be associated with better survival than chemotherapy
CONCLUSION: Surgery may be more beneficial for the patients who receive chemotherapy. Our results support evaluation of sequential multimodal treatments strategy including surgery and chemotherapy in patients with advanced STS.PMID:38521760 | DOI:10.1016/j.jfma.2024.03.007 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 23, 2024 Category: General Medicine Authors: Ching-Tso Chen Hsing-Wu Chen Wei-Hsin Lin Pei-Ming Huang Mong-Wei Lin Ching-Yao Yang Che-Yu Hsu Chia-Chun Wang Jen-Chieh Lee Koping Chang Kuo-Hao Huang Ho-Min Chen Tom Wei-Wu Chen Rong-Sen Yang Ruey-Long Hong Source Type: research
Understanding the mental health impacts of biological disasters: Lessons from Taiwan's experience with COVID-19
This article reviews mental health studies conducted in Taiwan during the pandemic, emphasizing the need to integrate this research for future preparedness and interventions regarding the mental health impacts of biological disasters, including COVID-19. Further research is essential to explore long-term effects, interventions, and generalizability.PMID:38519322 | DOI:10.1016/j.jfma.2024.03.015 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 22, 2024 Category: General Medicine Authors: Chih-Chieh Chang Kuan-Ying Hsieh Su-Ting Hsu Yu-Yuan Wang Frank Huang-Chih Chou Joh-Jong Huang Source Type: research
Understanding the mental health impacts of biological disasters: Lessons from Taiwan's experience with COVID-19
This article reviews mental health studies conducted in Taiwan during the pandemic, emphasizing the need to integrate this research for future preparedness and interventions regarding the mental health impacts of biological disasters, including COVID-19. Further research is essential to explore long-term effects, interventions, and generalizability.PMID:38519322 | DOI:10.1016/j.jfma.2024.03.015 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 22, 2024 Category: General Medicine Authors: Chih-Chieh Chang Kuan-Ying Hsieh Su-Ting Hsu Yu-Yuan Wang Frank Huang-Chih Chou Joh-Jong Huang Source Type: research
Comment on "Impact of post-implantation time on bioresorbable vascular scaffold outcomes for type C versus non-type C coronary lesions: A longer-term study"
J Formos Med Assoc. 2024 Mar 21:S0929-6646(24)00143-8. doi: 10.1016/j.jfma.2024.02.017. Online ahead of print.NO ABSTRACTPMID:38514371 | DOI:10.1016/j.jfma.2024.02.017 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 21, 2024 Category: General Medicine Authors: Yang Xie Parhati Turson Jianping Wang Dongqing An Source Type: research
