Activity Recognition for Anomalous Situations Detection
ConclusionOur method allows, on one hand, recognizing user activities and, on the other hand, detecting eventual occurrence of anomalies in the user's situation. It proves to be efficient using the tested datasets for each module. However, in order to obtain a more general conclusion we plan to evaluate the method using more different datasets.Graphical abstract (Source: IRBM)
Source: IRBM - November 11, 2018 Category: Biomedical Engineering Source Type: research

Editorial Board
Publication date: November 2018Source: IRBM, Volume 39, Issue 5Author(s): (Source: IRBM)
Source: IRBM - November 3, 2018 Category: Biomedical Engineering Source Type: research

Preliminary Investigation of a 64-element Capacitive Micromachined Ultrasound Transducer (CMUT) Annular Array Designed for High Intensity Focused Ultrasound (HIFU)
ConclusionThis work demonstrates the feasibility of utilizing a planar CMUT probe for generating dynamic HIFU focusing and lesioning compatible with the ablation of prostate tissues under endocavitary treatment approach. Future investigations will consist of validating the lesioning capability experimentally both in vitro and in vivo.Graphical abstract (Source: IRBM)
Source: IRBM - October 27, 2018 Category: Biomedical Engineering Source Type: research

Plas'O'Soins: An Interactive ICT Platform to Support Care Planning and Coordination within Home-Based Care
ConclusionThe software platform has been deployed and used in an experimental setting by homecare partner organizations, providing valuable insights on the organizational changes required by the introduction of such an ICT solution in the actual practice of homecare.Graphical abstract (Source: IRBM)
Source: IRBM - October 26, 2018 Category: Biomedical Engineering Source Type: research

ReSynPlex: Respiratory Syndrome Linked Pathogens Multiplex Detection and Characterization
ConclusionThe HIFI Resp product based on a sample-to-result syndromic approach, with a minimum user intervention during the procedure on a cost efficient automated platform and a short time of analysis is a promising device.Graphical abstract (Source: IRBM)
Source: IRBM - October 24, 2018 Category: Biomedical Engineering Source Type: research

Ultrasound Molecular Imaging with Targeted Microbubbles for Cancer Diagnostics: From Bench to Bedside
Publication date: Available online 23 October 2018Source: IRBMAuthor(s): J. Wischhusen, F. PadillaAbstractBackgroundUltrasound plays an important role in cancer diagnosis. B-mode imaging and contrast-enhanced ultrasound are routinely used to detect cancerous lesions in breast and liver. The use of ultrasound contrast agents (UCAs) such as microbubbles (MBs), which can be functionalized with targeting ligands, has further enabled ultrasound molecular imaging (USMI) of specific molecular markers in pre-clinical and the first clinical studies. As targeted MBs have a diameter of 1–4 μm, they are limited to the blood v...
Source: IRBM - October 24, 2018 Category: Biomedical Engineering Source Type: research

Two-Stage Feature Selection of Voice Parameters for Early Alzheimer's Disease Prediction
ConclusionThe proposed method improved the classification accuracy for ES-AD, MCI and HC groups and promises the effectiveness of speech analysis and machine learning techniques to help detect pathological diseases.Graphical abstract (Source: IRBM)
Source: IRBM - October 24, 2018 Category: Biomedical Engineering Source Type: research

Microwave Resonant Sensor for Non-invasive Characterization of Biological Tissues
ConclusionsThis paper presents an improved microwave sensor, either for reduced dimensions as for sensitivity, able to perform dielectric characterization of material having high complex permittivity such as biological tissues. Experiments and electromagnetic simulations have been achieved on several animal tissues (chicken, beef, pork …), and results are in good agreement with literature. Works are in progress to optimize this sensor as an applicator for medical applications.Graphical abstract (Source: IRBM)
Source: IRBM - October 24, 2018 Category: Biomedical Engineering Source Type: research

Detection of Movement Artefacts and Contraction Bursts Using Accelerometer and Electrohysterograms for Home Monitoring of Pregnancy
In this study, we investigated the detectability of a begin/end of contraction by analyzing EHG signals with the Bayes Information Criterion, and we analyzed the three axis accelerometer signals to characterize the mother activity when she is carrying the device (such movements being possible sources of artifacts in the EHG signals).ResultsFor the contraction detections, we obtained 68.38% (599/876) of good detection but a too high number of false alarms (1073). To reduce this false alarm number, we analyzed the three accelerometer signals and detected 98.7% of static phases of the mother and 95% of dynamic ones.Discussion...
Source: IRBM - October 23, 2018 Category: Biomedical Engineering Source Type: research

Serious Games for Home Based Rehabilitation: Inertial Sensor Energy Consumption
ConclusionFinally, these results allowed us to establish an optimal set up configuration for home based rehabilitation using serious games.Graphical abstract (Source: IRBM)
Source: IRBM - October 23, 2018 Category: Biomedical Engineering Source Type: research

Ergonomic Risk Assessment of Developing Musculoskeletal Disorders in Workers with the Microsoft Kinect: TRACK TMS
ConclusionLow-cost three-dimensional cameras can be a useful aid in ergonomic risk assessment of developing musculoskeletal disorders and give the example of the repetition of movements and postural items included in the OCRA checklist, whose scoring can be facilitated by such a device.Graphical abstract (Source: IRBM)
Source: IRBM - October 20, 2018 Category: Biomedical Engineering Source Type: research

A Framework for Service Robots in Smart Home: An Efficient Solution for Domestic Healthcare
ConclusionOur framework provides software tools that make robots and smart environments more relevant in real housings. By supporting the uncertainty of context data and the dynamism of the environment, robots and smart environments can achieve more effectively their purposes in domestic healthcare applications.Graphical abstract (Source: IRBM)
Source: IRBM - October 20, 2018 Category: Biomedical Engineering Source Type: research

Home-Based Adapted Physical Activity by Means of a Motivational Aide Solution
The objective of the Motiv@Dom project is to create motivational and enjoyable solutions to help seniors to practice an adapted OR appropriate physical activity at home. Faithful to the Living Lab approach, this project has adopted a user-centered and participative strategy. The users are involved throughout the design process of the Motiv@Dom solution, from the first ideas to the evaluation of the final product. In fact, we do our designing not only by placing the user at the center of our work, but above all “with the seniors” and “for the seniors”, giving them a role just as important as the othe...
Source: IRBM - October 20, 2018 Category: Biomedical Engineering Source Type: research

Laser-Generated Au Nanoparticles for Bio-Medical Applications
ConclusionsThe aim of this research is to transport the nanoparticles in places where tissue disease exists and reduce their concentration in healthy tissues. This permit a better observation of the diseased tissues and their preparation as targeting for radio- and thermal-therapy to be applied to damage tumor cells saving healthy tissues.Graphical abstract (Source: IRBM)
Source: IRBM - October 20, 2018 Category: Biomedical Engineering Source Type: research

Feasibility Study of the Elaboration of a Biodegradable and Bioactive Ligament Made of Poly(ε-caprolactone)-pNaSS Grafted Fibers for the Reconstruction of Anterior Cruciate Ligament: In Vivo Experiment
ConclusionThis work demonstrates the feasibility to implant a bioactive and biodegradable synthetic ligament in the rat model without any inflammation and with a good tissue anchoring at a short-term time. This will lead to an extensive in vivo assay.Graphical abstract (Source: IRBM)
Source: IRBM - October 20, 2018 Category: Biomedical Engineering Source Type: research

Automated Classification of Fatty and Normal Liver Ultrasound Images Based on Mutual Information Feature Selection
ConclusionThe experimental results show that the proposed system can be used for the classification of fatty and normal liver ultrasound images with higher accuracy.Graphical abstract (Source: IRBM)
Source: IRBM - October 20, 2018 Category: Biomedical Engineering Source Type: research

Semi-global Parameterization of Online Handwriting Features for Characterizing Early-Stage Alzheimer and Mild Cognitive Impairment
ConclusionA semi-global parametrization of handwriting spatiotemporal parameters allows for a better discrimination between the HC, MCI and ES-AD profiles, than a global one does. Unlike the latter, the former encodes the distribution of the dynamics of each parameter, which offers a larger parameter space in which discrimination is easier.Graphical abstract (Source: IRBM)
Source: IRBM - October 18, 2018 Category: Biomedical Engineering Source Type: research

Swallowing Sound Recognition at Home Using GMM
ConclusionThe proposal method has great potential to assist in the clinical evaluation using only swallowing sounds, which is a non-invasive technic for swallowing studies.Graphical abstract (Source: IRBM)
Source: IRBM - October 18, 2018 Category: Biomedical Engineering Source Type: research

AidAdom: Supporting Inter-Organizational Coordination for Home Help and Healthcare Services Through a Web Platform
ConclusionThe AidAdom platform provides a lightweight system which enables organizations to share a minimal set of coordination information. Our future work is oriented toward opening the system to new help and healthcare service professionals and organizations.Graphical abstract (Source: IRBM)
Source: IRBM - October 18, 2018 Category: Biomedical Engineering Source Type: research

Precise Cobb Angle Measurement System Based on Spinal Images Merging Function
ConclusionThe developed measurement system demonstrated its measurement performance accurately and practically.Graphical abstract (Source: IRBM)
Source: IRBM - October 14, 2018 Category: Biomedical Engineering Source Type: research

Computerised Decision Support System for Remote Health Monitoring: A Systematic Review
ConclusionThe proposed system includes the model that provides the correlations of several biosignals like electrocardiogram (ECG), peripheral capillary oxygen saturation (SPO2), body temperature and heartbeat, thereby identifying the critical situations and making the decisions using CDSS that helps in taking the necessary clinical interventions.Graphical abstract (Source: IRBM)
Source: IRBM - October 12, 2018 Category: Biomedical Engineering Source Type: research

Early Stage Chronic Kidney Disease Diagnosis by Applying Data Mining Methods to Urinalysis, Blood Analysis and Disease History
ConclusionA new automatic early stage CKD diagnosis method was proposed to help the medical doctors. Attributes that would provide the highest diagnosis success rate were the use of specific gravity, albumin, sugar and red blood cells together. Also, the relation between the success rate of automatic diagnosis method and age was identified.Graphical abstract (Source: IRBM)
Source: IRBM - October 11, 2018 Category: Biomedical Engineering Source Type: research

Eight Weeks of Local Vibration Training Do Not Increase Tibialis Anterior Muscle Stiffness Evaluated by Supersonic Shear Imaging
ConclusionOur results suggest that adaptations in elastic muscle properties do not explain the increased muscle strength reported after LV training.Graphical abstract (Source: IRBM)
Source: IRBM - October 5, 2018 Category: Biomedical Engineering Source Type: research

An Optimized Cascaded Stochastic Resonance for the Enhancement of Brain MRI
ConclusionThe cascaded DSR based on MOPSO has shown promising results and may be highly beneficial to the diagnosis of different brain pathology.Graphical abstract (Source: IRBM)
Source: IRBM - September 19, 2018 Category: Biomedical Engineering Source Type: research

Analysis of User Control Attainment in SMR-based Brain Computer Interfaces
ConclusionsThe study concludes that the slow control attainment in SMR-based BCIs is due to its reliance on user training (neural adaptation) which is adaptive but too slow in the context of SMR modulations and due to the weak decoding of the neuronal phenomenon utilised by the user. As a recommendation, the optimality of the feature selection algorithm could be looked at to guarantee the use of the most relevant features. However and most importantly the predictive power of the translation model should be significantly improved in order to quicken control attainment as thereafter the control attainment effort could be shi...
Source: IRBM - September 18, 2018 Category: Biomedical Engineering Source Type: research

Editorial Board
Publication date: August 2018Source: IRBM, Volume 39, Issue 4Author(s): (Source: IRBM)
Source: IRBM - August 1, 2018 Category: Biomedical Engineering Source Type: research

Notch Pathway: Bioinformatic Analysis of Related Transcription Factors within Bladder Cancer Types and Subtypes
ConclusionNotch signaling pathway regulators do not have the same activity within the different subtypes of bladder cancer and they can be divided into two groups that behave inversely. We showed for the first time that NOTCH3 does not have the same activity within bladder cancer categories and subtypes.Graphical abstract (Source: IRBM)
Source: IRBM - July 21, 2018 Category: Biomedical Engineering Source Type: research

A Simple Method to Functionalize PCL Surface by Grafting Bioactive Polymers Using UV Irradiation
ConclusionWe developed a new approach of radical grafting which allows us to successfully graft bioactive polymer polyNaSS covalently to PCL surfaces using UV irradiation.Graphical abstract (Source: IRBM)
Source: IRBM - July 21, 2018 Category: Biomedical Engineering Source Type: research

Therapeutic Ultrasound for the Heart: State of the Art
Publication date: Available online 2 December 2017Source: IRBMAuthor(s): P. Greillier, C. Bawiec, F. Bessière, C. LafonAbstractThis work describes the use of therapeutic ultrasound as a treatment of cardiovascular disease including recent, state of the art approaches. Therapeutic ultrasound researchers have made recent advances in the highly dynamic and changing world of interventional cardiology where they are confronted with several challenges, such as of the complexity of ultrasound propagation in the highly heterogeneous environment of the thorax or the complexity of the heart (in term of motion and physiology)....
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Shear-Wave Sources for Soft Tissues in Ultrasound Elastography
Publication date: Available online 1 February 2018Source: IRBMAuthor(s): B. Giammarinaro, A. Zorgani, S. CathelineAbstractElastography is an imaging tool for soft-tissue characterization in the human body, and it is based on the propagation of shear waves. Since its first use in the ultrasound landscape, the generation of shear waves has had practical and theoretical issues. In this review, the use of four methods of shear-wave generation are considered: an external vibrating source; a radiation pressure source; a natural source; and an electromagnetic source. The pros and cons of these methods are detailed and discussed. (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

EEG Based Brain Computer Interface for Controlling a Robot Arm Movement Through Thought
ConclusionThe results obtained would encourage, with further developments, the use of the proposed BCI to perform more complex tasks such as execution of successive movements or stopping the execution once a searched object is detected. This would provide a useful assistance means for people with motor impairment.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

A Simple Method for Measuring the Changeable Mechanical Action of Unloader Knee Braces for Osteoarthritis
Publication date: April 2018Source: IRBM, Volume 39, Issue 2Author(s): E. Cusin, J.L. Honeine, M. Schieppati, P.R. RougierAbstractPurposeToday's orthotics should be designed to apply the external orthosis moment to the knee joint solely during the stance phase instead of the entire gait cycle. The aim of this study was to validate the reliability of a simple device for measuring forces at the leg–orthosis interface and describe the behavior of an innovating dynamic unloader knee brace built to interrupt its mechanical action during large knee flexion (swing phase of gait).MethodsA compression testing machine was used...
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

A Comparative Study of Two Ambulatory Core Temperature Assessment Methods
Conclusion. The non-invasive ZHF sensor gave an accurate estimation of TCOpill in steady state but not during exercise. However, complementary results let suppose that ZHF performance is not affected by ambient conditions and could be a relevant alternative for deep body temperature measurement during whole-body heat stress.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Editorial Board
Publication date: April 2018Source: IRBM, Volume 39, Issue 2Author(s): (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

ClinMine: Optimizing the Management of Patients in Hospital
ConclusionThe project ClinMine aimed at dealing with hospital data in order to provide a better understanding of “patient pathway”. The two methods proposed here show their ability to simultaneously deal with heterogeneous data, including temporal aspects, and manages to give information for the understanding of “patient pathway” (identification of interesting clusters of patients).Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

INFLAM – INFLAMmation in Brain and Vessels with Iron Nanoparticles and Cell Trafficking: A Multiscale Approach of Tissue Microenvironment, Iron Nanostructure and Iron Biotransformation
ConclusionThis review presents the contribution of the collaborative research project under the “TecSan” grant from the French Research Agency (ANR) as well as pre-clinical and clinical perspectives of USPIO's inflammation MRI in atherosclerosis and stroke.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

FibriDerm: Interpenetrated Fibrin Scaffolds for the Construction of Human Skin Equivalents for Full Thickness Burns
ConclusionThe FibriDerm project has the ambition to lead to the development of new materials for tissue regeneration, from the initial research developments and optimizations up to pre-clinical stages, via an interdisciplinary approach.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Feasibility Test of Three Dimensional Intermittent Oro-Esophageal Tube Guide for Dysphagia; Biocompatibility and Pilot Case Study
Conclusion: This tendency increases feasibility of the customized IOE tube. We are still recruiting subjects for statistical significance of our trial.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Semi-automatic Method for Low-Grade Gliomas Segmentation in Magnetic Resonance Imaging
Conclusion: The comparison of the proposed method, shows more accurate results than the four existing methods.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

DoRGaN: Development of Quality Assurance and Quality Control Systems for High Dose Rate Brachytherapy Based on GaN Dosimetry Probes
ConclusionFor developing systems for HDR-BT, the GaN probe has been shown to meet requirements for high sensitivity, high measurement rate, small response anisotropy and large dose measurement range. The proposed QA instrumented phantom has comparable or better characteristics when compared with diode-based and Al2O3:C-based systems. The other QC gynecological applicator has higher time and spatial resolutions than the state-of-the-art IVD systems, which proves that it is suitable for real-time monitoring of HDR-BT physical parameters.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

3D Sequential Kinematics of the Femoro-Tibial Joint of Normal Knee from Multiple Bi-planar X-rays: Accuracy and Repeatability
ConclusionCompared to simple fluoroscopy, the accuracy of our method based on sequential images was of the same order of magnitude, with better results for the translation in the frontal plane. The low dose of radiation of the EOS system offers promising prospects for a clinical use of this method to assess the femoro-tibial sequential kinematics.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Improvements of Liver MR Imaging Clinical Protocols to Simultaneously Quantify Steatosis and Iron Overload
ConclusionManufacturer's tools were improved to simultaneously quantify liver markers saving time for the patient and the clinical setting. These parameters are of great value for clinical diagnostics and novel therapeutics to treat liver diseases.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Sleep Apnea Detection from Single-Lead ECG Using Features Based on ECG-Derived Respiration (EDR) Signals
ConclusionsOur OSA detection system using EDRs features yields better independent test results compared with other state-of-the-art automatic apnea detection methods. The results indicate that ECG-based OSA detection system can classify OSA events with high accuracy and suggest a promising, non-invasive and efficient method for apnea detection.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Editorial Board
Publication date: June 2018Source: IRBM, Volume 39, Issue 3Author(s): (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Preview Distance Index for the Analysis of Powered Wheelchair Driving
Conclusion  This work showed that Dp allows to differentiate accustomed users from the novice ones using a test on healthy subjects. A second test on subjects with disabilities showed that this indicator can be used for analysing their abilities to drive the PW.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Generalized Framework for Control of Redundant Manipulators in Robot-Assisted Minimally Invasive Surgery
ConclusionsThe results showed the capacity of the proposed framework to simultaneously comply the three tasks: the tool-tip trajectory, the RCM constraint and joint compliance in case of collisions in the robot's body, always respecting the priority order between the tasks.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Building Automation, an Acceptable Solution to Dependence? Responses Through an Acceptability Survey About a Sensors Platform
ConclusionOur results suggest that an automated system is acceptable by the target organisations under various practical, ethical, social and financial criteria. Our research thus also demonstrate the importance to adopt a social-technique approach that means to consider simultaneously social and technical dimensions in any system developmentGraphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Intelligent Touchscreen Joystick for Controlling Electric Wheelchair
ConclusionIn this article, we explored an intelligent touchscreen solution that will address the problems faced by our target users. We conducted a thorough research on the types of existing control interfaces. We found that most of these interfaces use a discrete control of speed and direction. After testing it with a group of disabled users, we noticed the importance of analogic control. As part of our iterative design approach, we designed a prototype that provides this analogic control and in which we have implemented a calibration algorithm based on the neural networks algorithm.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Interoperable Infrastructure and Implementation of a Health Data Model for Remote Monitoring of Chronic Diseases with Comorbidities
ConclusionFor the remote monitoring of patients with multiple chronic conditions, we developed a generic architecture that allows different telemedicine applications associated with specific diseases to share a common technical platform. This work was to propose at first, a health data model for the patient's vital signs, and, on the other hand second, a study of communication standards to achieve an interoperable system.Graphical abstract (Source: IRBM)
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research

Review on Biomedical Techniques for Imaging Electrical Impedance
Publication date: Available online 3 July 2018Source: IRBMAuthor(s): P. Grasland-Mongrain, C. LafonAbstractElectrical impedance of a medium helps to predict the behavior of electrical currents in a medium. Electrical impedance refers indeed to the “difficulty”, for an electrical current, to spread through the medium. While the first impedance measurements were focused on cardiovascular parameters, techniques are now being applied to the whole body, as electrical impedance present important variations through the human body and could then offer a new source of contrast.Combining electrical current, magnetic fiel...
Source: IRBM - July 10, 2018 Category: Biomedical Engineering Source Type: research