Elevated HSP70 and HSP90 as Predictive Markers of Immune Activation and Lung Injury in SARS-COV-2 Disease
CONCLUSION: HSP90 and HSP70 contribute to excessive immune responses and cytokine storms. They may serve as prognostic serum markers for COVID-19 lung injury. Additionally, they are candidates for anti-inflammatory therapy.PMID:37606151 | DOI:10.22034/iji.2023.97202.2488 (Source: Iranian Journal of Immunology)
Source: Iranian Journal of Immunology - August 22, 2023 Category: Allergy & Immunology Authors: Zivar Zangeneh Gholamreza Khamisipour Source Type: research
Effects of Blocking NLRP3 Inflammasome on Type II Innate Lymphoid Cell Response in Allergic Rhinitis
CONCLUSION: MCC950 inhibited ILC2 responses in AR and mice models, suggesting that blocking NLRP3 inflammasome may be a promising target for AR clinical treatment.PMID:37583131 | DOI:10.22034/iji.2023.96966.2473 (Source: Iranian Journal of Immunology)
Source: Iranian Journal of Immunology - August 16, 2023 Category: Allergy & Immunology Authors: Guoqing Gong Peng Huang Changliang Yang Chengcheng Huang Zhao Zhang Ruiyao Chen Tingfeng Sun Guang Yang Source Type: research
Neutrophil Extracellular Traps Formation and Citrullinated Histones 3 Levels in Patients with Kawasaki Disease
CONCLUSION: Acute KD is characterized by an increased formation of NETs and high levels of H3Cit. IVIG significantly inhibited NETs formation and also reduced the level of plasma H3Cit in children with KD.PMID:37551669 | DOI:10.22034/iji.2023.97562.2523 (Source: Iranian Journal of Immunology)
Source: Iranian Journal of Immunology - August 8, 2023 Category: Allergy & Immunology Authors: Jing Hu Wei Qian Tianhe Wang Jingjing Ling Yingzuo Shi Source Type: research
