Molecular detection of parvovirus in Manchurian chipmunks (Tamias sibiricus asiaticus) captured in Korea
Cross-species transmission of viral diseases alarms our global community for its potential of novel pandemic events. Of various viral pathogens noted recently, parvoviruses have posed public health threats not only to humans but to wild animals. To investigate the prevalence of parvoviruses in wild Manchurian chipmunks, here we detected genetic fragments of the nonstructural protein of parvovirus by polymerase chain reaction in wild Manchurian chipmunk specimens captured in the central and southern regions of South Korea and compared their sequence homology with references. Of a total of 348 specimens examined, chipmunk pa...
Source: Intervirology - October 25, 2021 Category: Virology Source Type: research

Hepatitis E virus capsid as a carrier of exogenous antigens for the development of chimeric virus-like particles
(Source: Intervirology)
Source: Intervirology - October 25, 2021 Category: Virology Source Type: research

Acknowledgement to Reviewers
Intervirology 2021;64:215 –216 (Source: Intervirology)
Source: Intervirology - October 20, 2021 Category: Virology Source Type: research

The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)
Background: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is currently the most important etiological agent of acute respiratory distress syndrome (ARDS) with millions of infections and deaths in the last two years worldwide. Several reasons and parameters are responsible for the difficult management of coronavirus disease-2019 (COVID-19) patients; the first is virus behavioral factors such as high transmission rate, and the different molecular and cellular mechanisms of pathogenesis remain a matter of controversy, is another factor. Summary: In the present review, we attempted to explain about features ...
Source: Intervirology - October 19, 2021 Category: Virology Source Type: research

Seroprevalence, Genotyping, and Monitoring of Hepatitis C Viral Loads in Patients on Antivirals in Burkina Faso
Conclusion: The responses to antivirals by the circulating genotypes indicate that the results are very satisfactory. Therefore, the prevalence of HCV in the population can be reduced through identification of cases and treatment. (Source: Intervirology)
Source: Intervirology - September 28, 2021 Category: Virology Source Type: research

Seroprevalence, genotyping and monitoring of hepatitis C viral loads in patients on antivirals in Burkina Faso
(Source: Intervirology)
Source: Intervirology - September 28, 2021 Category: Virology Source Type: research

Adverse Events following AstraZeneca COVID-19 Vaccine in Saudi Arabia: A Cross-Sectional Study among Healthcare and Nonhealthcare Workers
Conclusion: The reported side effects were common but not pressing in both groups. HCW respondents appeared to have more COVID-19 vaccine-associated symptoms. (Source: Intervirology)
Source: Intervirology - September 20, 2021 Category: Virology Source Type: research

Adverse Events Following AstraZeneca COVID-19 Vaccine in Saudi Arabia: A Cross-Sectional Study among Healthcare and Non-healthcare Workers
(Source: Intervirology)
Source: Intervirology - September 20, 2021 Category: Virology Source Type: research

Low-intensity ultrasound as a novel strategy to improve the cytotoxic effect of oncolytic reovirus on colorectal cancer model cells
(Source: Intervirology)
Source: Intervirology - September 10, 2021 Category: Virology Source Type: research

Prevalence of Hepatitis B Virus Infection Markers among Patients of the Ibn Sina University Hospital Center (Rabat, Morocco)
Conclusion: This study highlights a higher prevalence of HBsAg in the hospital-based population than the general population reported previously in Morocco and a very low HBV immunization coverage. Of particular interest, detectable HBV DNA levels in isolated HBcAb patients show that exclusive HBsAg screening cannot eliminate the risk of HBV transmission in certain cases. Many efforts are then mandatory to promote serological testing and increase the vaccination rate to limit viral dissemination for better management of this disease in Morocco. (Source: Intervirology)
Source: Intervirology - September 10, 2021 Category: Virology Source Type: research

Prevalence of Hepatitis B virus infection markers among patients of Ibn Sina University Hospital Center (Rabat, Morocco)
(Source: Intervirology)
Source: Intervirology - September 10, 2021 Category: Virology Source Type: research

Updating on roles of HIV intrinsic factors: a review of their antiviral mechanisms and emerging functions
(Source: Intervirology)
Source: Intervirology - August 31, 2021 Category: Virology Source Type: research

The Regulation of Prototype Foamy Virus 5 ′Long Terminal Repeats and Internal Promoter by Endogenous Transcription Factors
Conclusion: NF- κB had a negative effect on PFV 5′LTR and IP promoter activities, the PKC pathway might upregulate 5′LTR and IP promoter activities, and the JNK and NF-AT signal pathway could increase the Tas-regulated promoter activity of PFV 5′LTR. This study sheds light on the interaction between PFV and the host cell and may help utilize the viral promoters in retroviral vectors designed for gene transfer experiments.Intervirology (Source: Intervirology)
Source: Intervirology - August 26, 2021 Category: Virology Source Type: research

Emergence of a Novel Reassortant H5N3 Avian Influenza Virus in Korean Mallard Ducks in 2018
Conclusions: The HA antigenic relationship of A/mallard duck/South Korea/KNU18-91/2018 (H5N3) showed differences toward one of the old low-pathogenic H5N3 viruses in Korea. These results indicated that a novel reassortment low-pathogenic avian influenza H5N3 subtype virus emerged in South Korea in 2018 via novel multiple reassortments with Eurasian viruses, rather than one of old Korean H5N3 strains.Intervirology (Source: Intervirology)
Source: Intervirology - August 26, 2021 Category: Virology Source Type: research

HIV-HCV Coinfection: Prevalence and Treatment Outcomes in Malaysia
Conclusion: The current study shows that HCV infection has an impact on the recovery of CD4 cells of the patients on HAART. Screening of HCV among HIV patients who were smokers and intravenous drug users should be monitored before starting HAART.Intervirology (Source: Intervirology)
Source: Intervirology - August 26, 2021 Category: Virology Source Type: research