Using image J to document healing in ulcers of the foot in diabetes
Abstract The aim of the study was to assess the reliability of measuring the cross‐sectional area of diabetic foot ulcers using Image J software. The inter‐ and intra‐rater reliability of ulcer area measures were assessed using digital images of acetate tracings of ulcers of the foot affecting 31 participants in an off‐loading randomised trial. Observations were made independently by five specialist podiatrists, one of whom was experienced in the use of Image J software and educated the other four in a single session. The mean (±SD) of the mean cross‐sectional areas of the 31 ulcers determined independentl...
Source: International Wound Journal - June 13, 2017 Category: Surgery Authors: William J Jeffcoate, Alison J Musgrove, Nadina B Lincoln Tags: ORIGINAL ARTICLE Source Type: research

Refractory venous leg ulcers: observational evaluation of innovative new technology
Abstract This observational case series reports the evaluation of a novel neuromuscular electrical stimulation device (geko™) that stimulates the common peroneal nerve at the fibular head as an adjunctive therapy in patients with non‐healing venous leg ulcers. The aim was to evaluate and determine if the geko™ device was effective in this population and should be added to the medical supply formulary. Patients whose wounds had failed to heal within 24 weeks of standard therapy were identified in two community settings in Ontario. A total of 11 patients consented to the evaluation with a combined 107‐year hi...
Source: International Wound Journal - June 1, 2017 Category: Surgery Authors: Connie Harris, Amanda Loney, Jillian Brooke, Amanda Charlebois, Lucy Coppola, Sowmil Mehta, Norman Flett Tags: ORIGINAL ARTICLE Source Type: research

The posterior thigh flap for defect coverage of ischial pressure sores  – a critical single‐centre analysis
ABSTRACT The development of pressure sores is still not only an enormous economical but also a medical burden. Especially in the ischial region, the local defect coverage remains demanding as it is the main weight‐bearing area in wheelchair‐mobilised patients and is prone to high mobility. The purpose of our study was to report our long‐time experience with the reconstruction of ischial pressure ulcers with the medially based posterior thigh flap. A retrospective analysis of all primary pressure sores grade III–IV in the ischial area, which were covered with a medially based posterior thigh flap between January...
Source: International Wound Journal - June 1, 2017 Category: Surgery Authors: Gabriel Djedovic, Evi M Morandi, Julia Metzler, Anna Wirthmann, Johannes Matiasek, Thomas Bauer, Ulrich M Rieger Tags: ORIGINAL ARTICLE Source Type: research

Re: Epidermal skin grafting in vitiligo: a pilot study
(Source: International Wound Journal)
Source: International Wound Journal - June 1, 2017 Category: Surgery Authors: Kun ‐Lin Cheng, Chang‐Cheng Chang, Yen‐Jen Wang Tags: LETTER TO THE EDITOR Source Type: research

Palpation for pressure ulcers: examining the bony prominence and physical properties of the wound
(Source: International Wound Journal)
Source: International Wound Journal - June 1, 2017 Category: Surgery Authors: Yoshiko Takahashi, Fumihiro Mizokami, Zenzo Isogai Tags: LETTER TO THE EDITOR Source Type: research

Assessing and comparing the quality of wound centres: a literature review and benchmarking pilot
This study aims to assess the evidence concerning quality by describing the state of the art of wound centres and organisational effectiveness by developing indicators of quality and by assessing their suitability in a pilot study. A multi‐method approach was used: a literature review performed resulted in the development of an indicator list that was consequently subjected to expert review, and a benchmark study was completed comparing eight wound centres in the Netherlands. We thus provide a description of the relevant state‐of‐the‐art aspects of wound centre organisation, which were multidisciplinary collaborati...
Source: International Wound Journal - June 1, 2017 Category: Surgery Authors: Lotte Pruim, Anke Wind, Wim H. Harten Tags: ORIGINAL ARTICLE Source Type: research

A quality control circle process to improve implementation effect of prevention measures for high ‐risk patients
Abstract The aim of the study was to analyse the influence of prevention measures on pressure injuries for high‐risk patients and to establish the most appropriate methods of implementation. Nurses assessed patients using a checklist and factors influencing the prevention of a pressure injury determined by brain storming. A specific series of measures was drawn up and an estimate of risk of pressure injury determined using the Braden Scale, analysis of nursing documents, implementation of prevention measures for pressure sores and awareness of the system both before and after carrying out a quality control circle (QCC) p...
Source: International Wound Journal - June 1, 2017 Category: Surgery Authors: Haixia Feng, Guohong Li, Cuirong Xu, Changping Ju, Peiheng Suo Tags: ORIGINAL ARTICLE Source Type: research

Education and process change to improve skin health in  a residential aged care facility
We report on an intervention and evaluation in relation to changes in staff knowledge, time spent on healing and wound prevention and proportion of wounds in the facilities before and after. A rapid review of recent peer‐reviewed literature (2006–2016) found 14 education‐based intervention articles and provided the background and context for this intervention. A cohort of 164 nurses and personal care workers and 261 residents at two aged care‐approved facilities contributed to this intervention on the effect of education, mentoring and practice change on staff knowledge and wound prevalence between 2015 and 201...
Source: International Wound Journal - May 26, 2017 Category: Surgery Authors: Kay Price, Kate J Kennedy, Tabatha L Rando, Anthony R Dyer, Jo Boylan Tags: ORIGINAL ARTICLE Source Type: research

Development and psychometric validation of PUKAT 2 ·0, a knowledge assessment tool for pressure ulcer prevention
Abstract The aim of this study was to develop a tool to measure the knowledge of nurses on pressure ulcer prevention. PUKAT 2·0 is a revised and updated version of the Pressure Ulcer Knowledge Assessment Tool (PUKAT) developed in 2010 at Ghent University, Belgium. The updated version was developed using state‐of‐the‐art techniques to establish evidence concerning validity and reliability. Face and content validity were determined through a Delphi procedure including both experts from the European Pressure Ulcer Advisory Panel (EPUAP) and the National Pressure Ulcer Advisory Panel (NPUAP) (n = 15)...
Source: International Wound Journal - May 26, 2017 Category: Surgery Authors: B énédicte Manderlier, Nele Van Damme, Katrien Vanderwee, Sofie Verhaeghe, Ann Van Hecke, Dimitri Beeckman Tags: ORIGINAL ARTICLE Source Type: research

Education and process change to improve skin health in a residential aged care facility
We report on an intervention and evaluation in relation to changes in staff knowledge, time spent on healing and wound prevention and proportion of wounds in the facilities before and after. A rapid review of recent peer‐reviewed literature (2006–2016) found 14 education‐based intervention articles and provided the background and context for this intervention. A cohort of 164 nurses and personal care workers and 261 residents at two aged care‐approved facilities contributed to this intervention on the effect of education, mentoring and practice change on staff knowledge and wound prevalence between 2015 and 201...
Source: International Wound Journal - May 26, 2017 Category: Surgery Authors: Kay Price, Kate J Kennedy, Tabatha L Rando, Anthony R Dyer, Jo Boylan Tags: ORIGINAL ARTICLE Source Type: research

Successful treatment of smallpox scars by using radiofrequency device with single microneedle
(Source: International Wound Journal)
Source: International Wound Journal - May 26, 2017 Category: Surgery Authors: Kwang Ho Yoo, Ga Ram Ahn, Joon Seok, Yu ‐Jin Jang, Beom Joon Kim Tags: LETTER TO THE EDITOR Source Type: research

Hidradenitis suppurativa complicated by squamous cell carcinoma: isoscartopic response
(Source: International Wound Journal)
Source: International Wound Journal - May 25, 2017 Category: Surgery Authors: Stefano Caccavale, Tobia Caccavale, Maddalena La Montagna Tags: LETTER TO THE EDITOR Source Type: research

A prospective evaluation of methylene blue and gentian violet dressing for management of chronic wounds with local infection
The objective of this prospective, non‐randomised study was to evaluate the performance of an antibacterial foam dressing containing methylene blue and gentian violet (Hydrofera Blue Classic dressing®) for the management of chronic wounds with local infection. Patients in this study were ≥18 years of age (n = 29), and each had at least one chronic wound ≥1 cm2 in size that showed signs of localised infection or critical colonisation but with good potential for healing based on clinical assessment. To all of these wounds, the dressing was applied and changed three times per week over ...
Source: International Wound Journal - May 16, 2017 Category: Surgery Authors: Kevin Y Woo, Jolene Heil Tags: ORIGINAL ARTICLE Source Type: research

Biofilms and delayed healing  – an in vitro evaluation of silver‐ and iodine‐containing dressings and their effect on bacterial and human cells
This study investigated whether there are differences in the ability of wound dressings to modulate certain factors known to affect wound healing. A selection of antimicrobial dressings (AQUACEL® Ag Extra™, AQUACEL® Ag+ Extra™, IODOFLEX™, ACTICOAT™ 7 and PROMOGRAN PRISMA™ matrix) were tested for their effect on both bacterial bioburden and human dermal fibroblasts. Some dressings underwent further evaluation for activity against Pseudomonas aeruginosa biofilms using a colony‐drip flow reactor model. The ability of in vitro biofilms to produce proteases, and the effect of PROMOGRAN PR...
Source: International Wound Journal - May 15, 2017 Category: Surgery Authors: Katie A Bourdillon, Craig P Delury, Breda M Cullen Tags: ORIGINAL ARTICLE Source Type: research

Biofilms and delayed healing – an in vitro evaluation of silver‐ and iodine‐containing dressings and their effect on bacterial and human cells
This study investigated whether there are differences in the ability of wound dressings to modulate certain factors known to affect wound healing. A selection of antimicrobial dressings (AQUACEL® Ag Extra™, AQUACEL® Ag+ Extra™, IODOFLEX™, ACTICOAT™ 7 and PROMOGRAN PRISMA™ matrix) were tested for their effect on both bacterial bioburden and human dermal fibroblasts. Some dressings underwent further evaluation for activity against Pseudomonas aeruginosa biofilms using a colony‐drip flow reactor model. The ability of in vitro biofilms to produce proteases, and the effect of PROMOGRAN PR...
Source: International Wound Journal - May 14, 2017 Category: Surgery Authors: Katie A Bourdillon, Craig P Delury, Breda M Cullen Tags: ORIGINAL ARTICLE Source Type: research

The use of medicinal plants in venous ulcers: a systematic review with meta ‐analysis
ABSTRACT The aim of this study was to systematically review the use of medicinal plants for the treatment of varicose ulcers. The databases used in the search were: Medline/Pubmed, Scopus, Cinhal, Lilacs and Web of Science. The selection process was divided into two phases: the reading of titles and abstracts and the full reading of selected articles. The item description was compared with the checklist of the Consolidated Standards of Reporting Trials. The initial search produced 3505 articles and seven were selected for inclusion in the systematic review. Of the included studies, 7 (100%) evaluated the reduction of the u...
Source: International Wound Journal - May 10, 2017 Category: Surgery Authors: Anderson L Freitas, Carla A Santos, Carlos AS Souza, Marco AP Nunes, Ângelo R Antoniolli, Wellington B da Silva, Francilene A da Silva Tags: ORIGINAL ARTICLE Source Type: research

Calendar
(Source: International Wound Journal)
Source: International Wound Journal - May 5, 2017 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

News and views
(Source: International Wound Journal)
Source: International Wound Journal - May 5, 2017 Category: Surgery Tags: NEWS Source Type: research

Pain – a personal perspective
(Source: International Wound Journal)
Source: International Wound Journal - May 5, 2017 Category: Surgery Authors: Douglas Queen Tags: EDITORIAL Source Type: research

Issue Information
(Source: International Wound Journal)
Source: International Wound Journal - May 5, 2017 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Embedded ring injury – a rare presentation with an atypical aetiology
We present this unusual case of an embedded ring after an insect bite on the patient's ring finger. The patient had worn the ring for the previous 5 years without removing it and did not report any discomfort or traumatic injury. We discuss this case in the context of previously reported cases of an embedded ring, a rare presentation in itself, highlighting the key differences in both this patient's aetiology and the risk factors associated with the presentation. (Source: International Wound Journal)
Source: International Wound Journal - April 27, 2017 Category: Surgery Authors: Benjamin J Langridge, Saif Ramman, Neil J Toft Tags: ORIGINAL ARTICLE Source Type: research

Biodegradable hydrogel ‐based biomaterials with high absorbent properties for non‐adherent wound dressing
ABSTRACT Dressing materials involve conventional gauzes and modern materials such as hydrogels and foam‐based biomaterials. Although the choice of dressing material depends on the type of wound, a dressing material is expected to be non‐cytotoxic. Additionally, moist dressing is considered appropriate to accelerate epithelialisation, while dry dressing may cause tissue damage during removal. An ideal dressing material is expected to provide a moist environment and degrade and release the drug for faster wound healing. Thus, we have designed a hydrogel‐based biodegradable dressing material to provide the moist environ...
Source: International Wound Journal - April 25, 2017 Category: Surgery Authors: Alok Kumar, Xiang Wang, Krishna Chaitanya Nune, RDK Misra Tags: ORIGINAL ARTICLE Source Type: research

BCG vaccination ‐induced suppurative lymphadenitis: four signs to pay attention to
ABSTRACT Suppurative lymphadenitis is one of the severe complication after BCG vaccination, but its diagnostic criteria and treatment guidelines have not yet been established. In this article, we describe a case of suppurative lymphadenitis caused by BCG vaccination and propose diagnostic criteria and treatment guidelines of the disease. The lymphadenitis was presented as skin involving mass and was completely extirpated. Pathological evaluation revealed a necrotising lymphadenitis, consistent with the diagnosis of BCG lymphadenitis. The patient was administered adjuvant medical treatment with anti‐TB medications (Isonia...
Source: International Wound Journal - April 19, 2017 Category: Surgery Authors: Sang Oon Baek, Hyo Sun Ko, Hyun Ho Han Tags: CASE REPORT Source Type: research

Factors for postoperative complications following pressure ulcer operation: stepwise multiple logistic regression analysis
Abstract Patients with pressure ulcers are generally older, have a long hospital stay and often have a variety of comorbidities. The decision to perform surgery for pressure ulcer management can be difficult because of concerns about the risk of postoperative complications. The aim of this study was to analyse the relationship between comorbid conditions and surgical outcomes in order to guide patient selection for pressure ulcer surgery. In 57 patients, data on age, defect size, operating time, hospital stay, body mass index, surgical site, mobility state, cardiac ischaemic history, diabetes, renal failure, ventilator dep...
Source: International Wound Journal - April 17, 2017 Category: Surgery Authors: Hyun Ho Han, Jun Gul Ko, Jong Won Rhie Tags: ORIGINAL ARTICLE Source Type: research

Histological analysis of hyalinised keloidal collagen formation in earlobe keloids over time: collagen hyalinisation starts in the perivascular area
Abstract Keloids grow and do not regress. They are characterised histologically by hyalinised keloidal collagen (HKC). HKC amounts vary, and the mechanism by which they form is unclear. To clarify how HKCs form and whether their formation associates with specific clinical features, we studied the histological findings of earlobe keloids and compared them with respective clinical features. A total of 50 earlobe keloids from 43 patients were used for histological analysis of keloid size (mm2), HKC area (mm2) and HKC area ratio (%). As a result, keloid durations ranged from 3 months to>13 years. Early‐stage keloid...
Source: International Wound Journal - April 1, 2017 Category: Surgery Authors: Noriko M Matsumoto, Wei ‐Xia Peng, Masayo Aoki, Satoshi Akaishi, Ryuji Ohashi, Rei Ogawa, Zenya Naito Tags: ORIGINAL ARTICLE Source Type: research

Embedded ring injury  – a rare presentation with an atypical aetiology
We present this unusual case of an embedded ring after an insect bite on the patient's ring finger. The patient had worn the ring for the previous 5 years without removing it and did not report any discomfort or traumatic injury. We discuss this case in the context of previously reported cases of an embedded ring, a rare presentation in itself, highlighting the key differences in both this patient's aetiology and the risk factors associated with the presentation. (Source: International Wound Journal)
Source: International Wound Journal - April 1, 2017 Category: Surgery Authors: Benjamin J Langridge, Saif Ramman, Neil J Toft Tags: ORIGINAL ARTICLE Source Type: research

Enzymatic debridement with collagenase in wounds and ulcers: a systematic review and meta ‐analysis
Abstract Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all kinds of wounds, compared to an alternative therapy, on wound healing, wound bed characteristics, cost‐effectiveness and the occurrence of adverse events. We conducted a systematic literature search on available literature in Cochrane databases, MEDLINE, EMBASE and CINAHL. Two investigators independently assessed the titles and abstracts of all randomised controlled trials obtained involving collagenase of all kinds of wounds based on inclusion criteri...
Source: International Wound Journal - April 1, 2017 Category: Surgery Authors: J érôme Patry, Virginie Blanchette Tags: ORIGINAL ARTICLE Source Type: research

A small ‘lick’ will sink a great ship: fulminant septicaemia after dog saliva wound treatment in an asplenic patient
ABSTRACT Capnocytophaga canimorsus is a bacterium transmitted through the saliva of dogs. An infection can cause severe sepsis with acral necrosis and is potentially fatal. Here, we report the case of a 41‐year‐old man who was infected through a wound that was licked by his dog. He went into septic shock with disseminated intravascular coagulation and subsequently lost both lower legs, his nose and all the fingers on both hands. (Source: International Wound Journal)
Source: International Wound Journal - April 1, 2017 Category: Surgery Authors: Evi M Morandi, Reinhard Pauzenberger, Christoph Tasch, Ulrich M Rieger, Gerhard Pierer, Gabriel Djedovic Tags: ORIGINAL ARTICLE Source Type: research

Management of necrotising fasciitis secondary to abdominal liposuction using a combination of surgery, hyperbaric oxygen and negative pressure wound therapy in a patient with burn scars
ABSTRACT Liposuction is the one of the most frequently performed cosmetic operations and usually has an easy recovery, with a reportedly low overall complication rate. Here, we report the case of a 60‐year‐old woman with type II diabetes mellitus and a previous burn injury of the abdomen who underwent abdominal liposuction and subsequently developed necrotising fasciitis. Following radical debridement, systemic antibiotic administration, negative pressure wound therapy and hyperbaric oxygen therapy, the wound healed completely. This case demonstrates the success of the combination treatment and highlights the need for ...
Source: International Wound Journal - April 1, 2017 Category: Surgery Authors: I ‐Han Chiang, Shun‐Cheng Chang, Chih‐Hsin Wang Tags: ORIGINAL ARTICLE Source Type: research

In vitro assessment of a novel, hypothermically stored amniotic membrane for use in a chronic wound environment
Abstract Chronic wounds require extensive healing time and place patients at risk of infection and amputation. Recently, a fresh hypothermically stored amniotic membrane (HSAM) was developed and has subsequently shown promise in its ability to effectively heal chronic wounds. The purpose of this study is to investigate the mechanisms of action that contribute to wound‐healing responses observed with HSAM. A proteomic analysis was conducted on HSAM, measuring 25 growth factors specific to wound healing within the grafts. The rate of release of these cytokines from HSAMs was also measured. To model the effect of these cyto...
Source: International Wound Journal - March 30, 2017 Category: Surgery Authors: John P McQuilling, Jeremy B Vines, Katie C Mowry Tags: ORIGINAL ARTICLE Source Type: research

Transforming growth factor β1 regulates the expression of CCN2 in human keratinocytes via Smad‐ERK signalling
Abstract Connective tissue growth factor (CCN2/CTGF) and transforming growth factor β1 (TGF‐β1) are important regulators of skin wound healing, but controversy remains regarding their expression in epithelial cell lineages. Here, we investigate the expression of CCN2 in keratinocytes during reepithelialisation and its regulation by TGF‐β1. CCN2 was detected in the epidermis of healing full‐thickness porcine wounds. Human keratinocytes were incubated with or without 10 ng/ml TGF‐β1, and signalling pathways were blocked with 10‐μM SIS3 or 20‐μM PD98059. Semi‐quantitative real‐...
Source: International Wound Journal - March 29, 2017 Category: Surgery Authors: Elizabeth Kiwanuka, Johan PE Junker, Elof Eriksson Tags: ORIGINAL ARTICLE Source Type: research

The potential benefits and harms of early feeding post ‐surgery: a literature review
Abstract The effect of nutrition on wound healing is widely recognized, with many studies highlighting the detrimental effect poor nutrition can have on wound healing. In addition, fasting pre‐, peri‐ and postoperatively can contribute to further protein catabolism, leading to morbidity and mortality. By reviewing the current literature, this work evaluates the potential benefits and harms from early feeding (EF) during the early stages postsurgery. Current randomised control trials suggest that the early introduction of nutrients post‐surgery may be beneficial for wound healing and recovery from surgery. Additionall...
Source: International Wound Journal - March 29, 2017 Category: Surgery Authors: Genevieve Abela Tags: ORIGINAL ARTICLE Source Type: research

Peri ‐vulvar reconstruction using internal pudendal artery perforator flap in female Fournier's gangrene
Abstract Fournier's gangrene in female patients has low incidence rate but high mortality rate compared with that in males, with many cases resulting in death at acute phase. This is due to the differences in male and female genital anatomy, which should be fully understood by physicians to increase the patient's survival rate. After crossing the acute phase of the disease by an appropriate treatment, it is important to reconstruct vaginal or vulvar defects according to the patient's three‐dimensional anatomical structures. Perforator flap based on internal pudendal artery is one of the ideal reconstructive techniques to...
Source: International Wound Journal - March 29, 2017 Category: Surgery Authors: Sang O Baek, Seong H Park, Jong W Rhie, Hyun H Han Tags: CASE REPORT Source Type: research

Dramatic resolution of disseminated pyoderma gangrenosum associated with monoclonal gammopathy after therapy with bortezomib and dexamethasone
Abstract Pyoderma gangrenosum (PG) is an uncommon inflammatory and ulcerative skin disorder, which is commonly associated with systemic conditions such as inflammatory bowel disease, arthritis and haematological malignancies. It is widely stated that control of the underlying diseases may lead to resolution of PG. However, standard of care dictates that patients suffering with monoclonal gammopathy of undetermined significance or smouldering multiple myeloma (MM) should not receive therapy unless they progress to symptomatic MM. Here, we report a woman in her 40s with a disseminated corticodependent PG, resistant to any tr...
Source: International Wound Journal - March 29, 2017 Category: Surgery Authors: Virginia Velasco ‐Tamariz, Gonzalo Carreño‐Tarragona, Fátima Tous‐Romero, Elena Gil‐de la Cruz, Estela Martín‐Clavero, Raquel Rivera‐Díaz Tags: CASE REPORT Source Type: research

Comment on ‘Effectiveness of a multi‐layer foam dressing in preventing sacral pressure ulcers for the early acute care of patients with a traumatic spinal cord injury: comparison with the use of a gel mattress’
(Source: International Wound Journal)
Source: International Wound Journal - March 28, 2017 Category: Surgery Authors: Amit Gefen, Nick Santamaria Tags: LETTER TO THE EDITOR Source Type: research

Benefits of intralesional injections of sodium thiosulfate in the treatment of calciphylaxis
ABSTRACT Calciphylaxis (CPX) is a rare calcifying thrombotic vasculopathy responsible for painful necrotic ulcers, with a high mortality rate, and its management is often difficult. Recently, intravenous infusions of sodium thiosulfate (STS) have shown efficacy. The aim of this study was to assess the efficacy of intralesional STS (IL STS) in four patients. Our aim was to assess the efficacy of IL STS in a prospective mono‐centric open study that included four patients with a biopsy‐proven cutaneous CPX. Four women (55–84 years old, mean age: 71·2 years) with a uremic (n = 1) or non‐uremic ...
Source: International Wound Journal - March 23, 2017 Category: Surgery Authors: Kirsi Isoherranen, Laura Bouchard, Nicolas Kluger Tags: ORIGINAL ARTICLE Source Type: research

Non ‐healing ischaemic digital ulcer in a systemic sclerosis patient: a challenging clinical case
Abstract Ischaemic digital ulcers (DUs) are an indicator of the severity of the microangiopathy in patients with systemic sclerosis (SSc). DUs are a frequent complication, affecting about 50% of patients with SSc, and are often recurrent. In cross‐sectional studies involving patients with SSc, the frequency of ischaemic DUs was 12–16% with a major impact on hand function and quality of life. Effective therapy for DUs remains elusive. Intravenous iloprost has been demonstrated to have a positive effect on healing of active DUs. Bosentan, an oral endothelin receptor antagonist, only showed a benefit in preventing the...
Source: International Wound Journal - March 17, 2017 Category: Surgery Authors: Sophie Blaise, Matthieu Roustit, Alexandra Forli, Bernard Imbert, Jean ‐Luc Cracowski Tags: ORIGINAL ARTICLE Source Type: research

Incidence and risks for surgical site infection after adult tibial plateau fractures treated by ORIF: a prospective multicentre study
This study was designed as a prospective and multicentre one to address this issue. From July to 15 November in 2014, 235 patients with tibial plateau fractures were treated by open reduction and internal fixation (ORIF) and followed up with complete data. Twelve patients (5·1%, 12/235) developed SSI, with 2·1% for deep SSI and 3·0% for superficial SSI. Most of them (10/12) occurred during the hospital stays. The median occurrence time was 6 days after operation (range, 2–26 days). We use univariate and multivariate logistic regression models to investigate the potential risk factors. In the univ...
Source: International Wound Journal - March 15, 2017 Category: Surgery Authors: Yanbin Zhu, Song Liu, Xiaolin Zhang, Wei Chen, Yingze Zhang Tags: ORIGINAL ARTICLE Source Type: research

Treatment of anticoagulated patients with negative pressure wound therapy
Abstract There is a paucity of evidence surrounding the use of negative pressure wound therapy (NPWT) in patients receiving anticoagulant medication. Guidelines generally recommend caution regarding the use of NPWT in anticoagulated patients in general, but areas of particular risk are frequently not highlighted. The US Food and Drug Authority (FDA) reported six mortalities between 2009 and 2011 in patients receiving NPWT. These mortalities were associated with the use of NPWT over vascular graft sites. The coagulation status of these patients was not reported. It is the authors' recommendation that guidelines regarding th...
Source: International Wound Journal - March 15, 2017 Category: Surgery Authors: Sharon L Boxall, Keryln Carville, Gavin D Leslie, Shirley J Jansen Tags: ORIGINAL ARTICLE Source Type: research

A high ‐resolution tape sensor improves the accuracy of applied pressure profiles during lower‐leg bandaging – results from a study using a fibre‐optic sensing tape
Abstract Compression bandaging is a mainstay practice in the treatment of conditions such as chronic wounds and lymphoedema. However, the ability of practitioners to measure bandage application to a desired pressure profile is difficult because of sensor limitations. We have used a novel fibre‐optic‐based, high‐resolution sub‐bandage pressure monitor to measure adherence to a target pressure gradient during compression bandaging. Participants of various experience (n = 46) were asked to bandage a lower‐leg manikin to a gradient of 40 (ankle) to 20 mmHg (proximal calf) in both a blinded trial and sub...
Source: International Wound Journal - March 10, 2017 Category: Surgery Authors: Luke A Parkinson, Malou van Zanten, Neil Piller, John W Arkwright Tags: ORIGINAL ARTICLE Source Type: research

Effectiveness of a polyhexanide irrigation solution on methicillin ‐resistant Staphylococcus aureus biofilms in a porcine wound model
Abstract Irrigation and removal of necrotic debris can be beneficial for proper healing. It is becoming increasingly evident that wounds colonized with biofilm forming bacteria, such as Staphylococcus aureus (SA), can be more difficult to eradicate. Here we report our findings of the effects of an irrigation solution containing propyl‐betaine and polyhexanide (PHMB) on methicillin‐resistant Staphylococcus aureus (MRSA) biofilms in a porcine wound model. Thirty‐nine deep partial thickness wounds were created with six wounds assigned to one of six treatment groups: (i) PHMB, (ii) Ringer's solution, (iii) hypochlorous a...
Source: International Wound Journal - March 7, 2017 Category: Surgery Authors: Stephen C Davis, Andrew Harding, Joel Gil, Fernando Parajon, Jose Valdes, Michael Solis, Alex Higa Tags: ORIGINAL ARTICLE Source Type: research

Comparison of fasciocutaneous V ‐Y and rotational flaps for defect coverage of sacral pressure sores: a critical single‐centre appraisal
ABSTRACT Pressure sore rates remain high in both nursing homes as well as in hospitals. Numerous surgical options are available for defect coverage in the sacral region. However, objective data is scarce as to whether a specific flap design is superior to another. Here, we aim to compare two fasciocutaneous flap designs for sacral defect coverage: the gluteal rotation flap and the gluteal V‐Y flap. All primary sacral pressure sores of grades III–IV that were being covered with gluteal fasciocutaneous rotational or V‐Y flaps between January 2008 and December 2014 at our institution were analysed. A total of 41 pat...
Source: International Wound Journal - March 6, 2017 Category: Surgery Authors: Gabriel Djedovic, Julia Metzler, Evi M Morandi, Tanja Wachter, Shafreena K ühn, Gerhard Pierer, Ulrich M Rieger Tags: ORIGINAL ARTICLE Source Type: research

An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing
This article provides an overview of the pathophysiology of wound healing and reviews the latest evidence on the application of the principal components of regenerative medicine (growth factors, stem cell transplantation, biomaterials and tissue engineering) as therapeutic targets. Improved knowledge and understanding of the pathophysiology of wound healing has pointed to new therapeutic targets. Regenerative medicine has the potential to underpin the design of specific target therapies in acute and chronic wound healing. This personalised approach could eventually reduce the burden of disease associated with wound healing...
Source: International Wound Journal - March 5, 2017 Category: Surgery Authors: Calver Pang, Amel Ibrahim, Neil W Bulstrode, Patrizia Ferretti Tags: INVITED REVIEW Source Type: research

Length of surgery and pressure ulcers risk in cardiovascular surgical patients: a dose –response meta‐analysis
ABSTRACT The aim of this study was to assess the relationship between length of surgery (LOS) and pressure ulcer (PU) risk in cardiovascular surgery patients. PubMed and Web of Science were systematically searched. We compared LOS difference between PU (+) group and PU (‐) group. We also examined the dose–response effect of this relationship. The mean LOS in the PU(+) groups ranged from 252·5 to 335·7 minutes, compared with 233·0 to 298·3 minutes in PU(−) groups. The LOS was higher in PU(+) groups compared with PU(−) groups [weighted mean difference (WMD) = 36·081 minu...
Source: International Wound Journal - March 2, 2017 Category: Surgery Authors: Hong ‐Lin Chen, Wang‐Qin Shen, Peng Liu, Kun Liu Tags: ORIGINAL ARTICLE Source Type: research

Wound management of ulcerated haemangioma of infancy – an audit
Abstract Haemangioma of infancy, a benign tumour of blood vessels, is the most common tumour of infancy. Ulceration, the most common complication, presents a unique wound care challenge. A retrospective audit of medical records of children with haemangioma of infancy who presented to the Royal Children's Hospital, Melbourne, Australia, between January 2000 and December 2014 was undertaken with an aim to examine wound management of ulcerated haemangioma of infancy. In total, 535 hospital medical records were identified as suitable, of which 352 were randomly selected and audited, of which 84 patients had ulcerated haemangio...
Source: International Wound Journal - March 1, 2017 Category: Surgery Authors: Zerina Lokmic, Taya Grainger, Nadeeja V Atapattu, Roderic J Phillips, Anthony J Penington Tags: ORIGINAL ARTICLE Source Type: research

Calendar
(Source: International Wound Journal)
Source: International Wound Journal - February 28, 2017 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

News and views
(Source: International Wound Journal)
Source: International Wound Journal - February 28, 2017 Category: Surgery Tags: NEWS Source Type: research

Education and improved clinical outcomes
(Source: International Wound Journal)
Source: International Wound Journal - February 28, 2017 Category: Surgery Authors: Keith Harding, Douglas Queen Tags: EDITORIAL Source Type: research

Issue Information
(Source: International Wound Journal)
Source: International Wound Journal - February 28, 2017 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Is hyperbaric oxygen therapy indispensable for saving mutilated hand injuries?
This study was performed to evaluate the efficacy of HBOT as an adjunctive therapy in patients with a mutilated hand injury. Between January 2006 and December 2014, 45 patients with a mutilated hand injury were enrolled. After reconstruction or revascularisation, patients underwent 120 minutes of HBOT with oxygen at 2·5 atmospheres absolute while breathing 100% oxygen. Outcomes such as amputee survival and surgery‐related complications were recorded. The patients were 38 men and 7 women with average age of 37·2 years (range 18–62). The mean defect area was 131·5 cm2 (range 40&ndas...
Source: International Wound Journal - February 28, 2017 Category: Surgery Authors: I ‐Han Chiang, Yuan‐Sheng Tzeng, Shun‐Cheng Chang Tags: ORIGINAL ARTICLE Source Type: research