Ozone therapy for the treatment of chronic wounds: A systematic review
Chronic wounds present a significant burden to the health care system and the patient. Ozone therapy has been proposed as a treatment for chronic wounds, potentially acting by eliciting mild oxidative stress or disinfection. The purpose of this systematic review is to evaluate the potential benefits and harms of ozone therapy as an advanced care intervention for chronic wounds. Studies were extracted from Google Scholar, PubMed, the Cochrane Library, and reference lists. General inclusion criteria included English‐language randomised human trials reporting the use of ozone therapy in the topical treatment of chronic woun...
Source: International Wound Journal - March 13, 2018 Category: Surgery Authors: Erin Fitzpatrick, Olivia J Holland, Jessica J Vanderlelie Tags: ORIGINAL ARTICLE Source Type: research

Predicting the likelihood of venous leg ulcer recurrence: The diagnostic accuracy of a newly developed risk assessment tool
The aim of this study was to validate a newly developed tool for predicting the risk of recurrence within 12 months of a venous leg ulcer healing. Performance of the tool to predict recurrence within a 12‐month period was assessed using Area Under the Receiver Operating Characteristic Curve (AUC) analysis. Multi‐site retrospective and prospective longitudinal studies were undertaken to validate a risk assessment tool for the recurrence of venous leg ulcers within 12 months. In the retrospective study (n = 250), 55% of venous leg ulcers recurred within 12 months, and the risk assessment total score ...
Source: International Wound Journal - March 13, 2018 Category: Surgery Authors: Kathleen J. Finlayson, Christina N. Parker, Charne Miller, Michelle Gibb, Suzanne Kapp, Rajna Ogrin, Jacinta Anderson, Kerrie Coleman, Dianne Smith, Helen E. Edwards Tags: ORIGINAL ARTICLE Source Type: research

Combination of resveratrol ‐containing collagen with adipose stem cells for craniofacial tissue‐engineering applications
This study combined collagen scaffolds and human adipose stem cells (hASCs) for oral mucosal and calvarial bone regeneration by using resveratrol (RSV), which affects the differentiation of mesenchymal stem cells. We have evaluated the effect of collagen scaffold‐containing RSV (collagen/RSV) scaffolds both in vitro and in vivo for their wound healing and bone regeneration potential. Scanning electron microscopy and immunostaining results reveal that hASCs adhere well to and proliferate on both collagen scaffolds and collagen/RSV scaffolds. Oral mucosal lesion experiments demonstrated that the collagen/RSV scaffold is mo...
Source: International Wound Journal - March 13, 2018 Category: Surgery Authors: Chih ‐Chien Wang, Chih‐Hsin Wang, Hsiang‐Cheng Chen, Juin‐Hong Cherng, Shu‐Jen Chang, Yi‐Wen Wang, Adrienne Chang, Jue‐Zong Yeh, Yi‐Huei Huang, Cheng‐Che Liu Tags: ORIGINAL ARTICLE Source Type: research

Closed ‐incision negative pressure therapy to reduce groin wound infections in vascular surgery: a randomised controlled trial
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - March 12, 2018 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - March 12, 2018 Category: Surgery Source Type: research

Prevention of pressure ulcers with a static air support surface: A systematic review
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - March 5, 2018 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - March 5, 2018 Category: Surgery Source Type: research

Functional characterisation of bioactive peptide derived from terrestrial snail Cryptozona bistrialis and its wound ‐healing property in normal and diabetic‐induced Wistar albino rats
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 26, 2018 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - February 26, 2018 Category: Surgery Source Type: research

Growth hormone ‐releasing peptide 6 prevents cutaneous hypertrophic scarring: early mechanistic data from a proteome study
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 21, 2018 Category: Surgery Source Type: research

Prevalence of skin tears in the extremities in inpatients at a hospital in Denmark
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 21, 2018 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - February 21, 2018 Category: Surgery Source Type: research

Prevalence of skin tears in the extremities in inpatients at a hospital in Denmark
Abstract The aims of the study were to determine the prevalence of skin tears in the extremities and to explore factors associated with development of skin tears in inpatients at a Danish hospital. The study was designed as a point prevalence survey and included 202 patients in the age range 19–99 (mean: 70·7, SD: 16·5). The patients were assessed for presence of skin tears, numbers, locations and previous skin tears. Data were collected using a data collection sheet developed for a previous study. The survey team consisted of four specialist nurses. Data were collected over a period of 24 hours spread ...
Source: International Wound Journal - February 21, 2018 Category: Surgery Authors: Susan Bermark, Britt Wahlers, Anne Liv Gerber, Peter Alshede Philipsen, Jette Skiveren Tags: ORIGINAL ARTICLE Source Type: research

What is the effect of exercise on wound healing in patients with venous leg ulcers? A systematic review
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 15, 2018 Category: Surgery Source Type: research

Systematic review of the use of Statistical Process Control methods to measure the success of pressure ulcer prevention
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 15, 2018 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - February 15, 2018 Category: Surgery Source Type: research

What is the effect of exercise on wound healing in patients with venous leg ulcers? A systematic review
Standard best practice for the treatment of venous leg ulcers (VLUs) is compression bandaging of the lower leg to reduce hydrostatic pressure. There is considerable variation in reported healing rates when using this gold‐standard approach; therefore, a systematic and robust evaluation of other interventions is required. Exercise interventions, in addition to standard compression therapy, could improve wound‐healing time and prevent their recurrence. We have conducted a systematic review to examine the effects of exercise on wound characteristics, including time to heal, size and recurrence, pain, quality of life, adve...
Source: International Wound Journal - February 15, 2018 Category: Surgery Authors: Daisy Smith, Rebecca Lane, Rosemary McGinnes, Jane O ’Brien, Renea Johnston, Lyndal Bugeja, Victoria Team, Carolina Weller Tags: ORIGINAL ARTICLE Source Type: research

Slow to heel: a literature review on the management of diabetic calcaneal ulceration
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 12, 2018 Category: Surgery Source Type: research

The ‘Two Bridges Technique’ for sternal wound closure. The use of vacuum‐assisted closure for the treatment of deep sternal wound defects: a centre‐specific technique
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 12, 2018 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - February 12, 2018 Category: Surgery Source Type: research

The ‘Two Bridges Technique’ for sternal wound closure. The use of vacuum‐assisted closure for the treatment of deep sternal wound defects: a centre‐specific technique
The objective is to describe the ‘Two Bridges Technique’ (TBT), which has proven to be successful and has been the standard technique at our centre for vacuum‐assisted closure (VAC) of post‐sternotomy mediastinitis. An extensive literature search was performed in four databases to identify all published articles concerning VAC for post‐sternotomy mediastinitis. Several VAC methods have been used; however, no article has described our specific technique. TBT consists of a two‐bridges construction using two types of foam with different pore sizes, which ensures an equally divided negative pressure over th...
Source: International Wound Journal - February 12, 2018 Category: Surgery Authors: Karl Waked, Philippe Ballaux, Dominique Goossens, Koen Cathenis Tags: ORIGINAL ARTICLE Source Type: research

Hyperbaric oxygen therapy and intermittent ischaemia in the treatment of chronic wounds
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - February 8, 2018 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - February 8, 2018 Category: Surgery Source Type: research

News and views
International Wound Journal,Volume 15, Issue 1, Page 6-7, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

Another Year, Another Reflection
International Wound Journal,Volume 15, Issue 1, Page 5-5, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

Calendar
International Wound Journal,Volume 15, Issue 1, Page 178-178, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

Issue Information
International Wound Journal,Volume 15, Issue 1, Page 1-4, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

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International Wound Journal,Volume 15, Issue 1, Page 6-7, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

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International Wound Journal,Volume 15, Issue 1, Page 5-5, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

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International Wound Journal,Volume 15, Issue 1, Page 178-178, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

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International Wound Journal,Volume 15, Issue 1, Page 1-4, February 2018. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Source Type: research

Time ‐dependent changes in extra‐domain A‐fibronectin concentration and relative amounts of fibronectin‐fibrin complexes in plasma of patients with peripheral arterial disease after endovascular revascularisation
In conclusion, high levels of EDA‐FN and FN‐fibrin complexes could have potential diagnostic value in the management of PAD patients after revascularisation, predicting restenosis risk. (Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Ma łgorzata Pupek, Dorota Krzyżanowska‐Gołąb, Daniel Kotschy, Wojciech Witkiewicz, Wiesława Kwiatkowska, Maria Kotschy, Iwona Kątnik‐Prastowska Tags: ORIGINAL ARTICLE Source Type: research

Closed ‐incision negative pressure therapy to reduce groin wound infections in vascular surgery: a randomised controlled trial
Abstract Groin wound infections pose a major problem in vascular surgery. Closed‐incision negative pressure therapy (ciNPT) was especially designed for the management of incisions at risk of surgical site infections. The aim of this study was to investigate whether ciNPT is able to reduce the incidence of wound infections after vascular surgery. Data on 132 consecutive patients, scheduled for vascular surgery with a longitudinal femoral cutdown, were collected prospectively. All patients were randomised either to the ciNPT group (n = 64) or the control group (n = 68) with conventional dressing...
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Michael Engelhardt, Norah A Rashad, Christian Willy, Christian M üller, Christian Bauer, Sebastian Debus, Tino Beck Tags: ORIGINAL ARTICLE Source Type: research

Prevention of pressure ulcers with a static air support surface: A systematic review
This study was a systematic review. Six electronic databases were consulted: Cochrane Library, EMBASE, PubMed (Medline), CINAHL (EBSCOhost interface), Science direct, and Web of Science. In addition, a hand search through reviews, conference proceedings, and the reference lists of the included studies was performed to identify additional studies. Potential studies were reviewed and assessed by 2 independent authors based on the title and abstract. Decisions regarding inclusion or exclusion of the studies were based on a consensus between the authors. Studies were included if the following criteria were met: reporting an or...
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Brecht Serraes, Martin van Leen, Jos Schols, Ann Van Hecke, Sofie Verhaeghe, Dimitri Beeckman Tags: ORIGINAL ARTICLE Source Type: research

Functional characterisation of bioactive peptide derived from terrestrial snail Cryptozona bistrialis and its wound ‐healing property in normal and diabetic‐induced Wistar albino rats
In this report, it was isolated from the terrestrial snail Cryptozona bistrialis by enzymatic digestion and was evaluated for its in vitro wound‐healing activity in NIH/3T3 mouse fibroblasts cell line and in vivo wound‐healing activity in normal and diabetic‐induced Wistar albino rats. The C. bistrialis protein was digested by the papain enzyme, and 21.79 kDa peptide (Cb‐peptide) was purified by reversed‐phase high‐performance liquid chromatography and identified by MALDI (matrix‐assisted laser desorption/ionization)‐TOF analysis. The isolated Cb‐peptide was characterised by various analytical meth...
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Selvakumari Ulagesan, Kamatchi Sankaranarayanan, Amutha Kuppusamy Tags: ORIGINAL ARTICLE Source Type: research

Growth hormone ‐releasing peptide 6 prevents cutaneous hypertrophic scarring: early mechanistic data from a proteome study
Hypertrophic scars (HTS) and keloids are forms of aberrant cutaneous healing with excessive extracellular matrix (ECM) deposition. Current therapies still fall short and cause undesired effects. We aimed to thoroughly evaluate the ability of growth hormone releasing peptide 6 (GHRP6) to both prevent and reverse cutaneous fibrosis and to acquire the earliest proteome data supporting GHRP6’s acute impact on aesthetic wound healing. Two independent sets of experiments addressing prevention and reversion effects were conducted on the classic HTS model in rabbits. In the prevention approach, the wounds were assigned to to...
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Maday Fern ández‐Mayola, Lázaro Betancourt, Alicia Molina‐Kautzman, Sucel Palomares, Yssel Mendoza‐Marí, Dayana Ugarte‐Moreno, Ana Aguilera‐Barreto, Yilian Bermúdez‐Álvarez, Vladimir Besada, Luis J. González, Ariana García‐Ojalvo, Ana Tags: ORIGINAL ARTICLE Source Type: research

Systematic review of the use of Statistical Process Control methods to measure the success of pressure ulcer prevention
Successful prevention of pressure ulcers is the end product of a complex series of care processes including, but not limited to, the assessment of vulnerability to pressure damage; skin assessment and care; nutritional support; repositioning; and the use of beds, mattresses, and cushions to manage mechanical loads on the skin and soft tissues. The purpose of this review was to examine where and how Statistical Process Control (SPC) measures have been used to assess the success of quality improvement initiatives intended to improve pressure ulcer prevention. A search of 7 electronic bibliographic databases was performed on ...
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Michael Clark, Trudie Young, Maureen Fallon Tags: ORIGINAL ARTICLE Source Type: research

Slow to heel: a literature review on the management of diabetic calcaneal ulceration
Abstract The diabetic heel ulcer (DHU) represents a reconstructive challenge to clinicians and the multidisciplinary team alike. It is traditionally viewed as a condition that is inherently difficult to treat due to the intrinsic anatomical vulnerabilities of the heel. In addition to this, several factors are associated with poorer end outcomes – namely, that of major amputation. These include peripheral vascular disease, infection/osteomyelitis and the size of the ulcer itself. In light of the significant morbidity, economic burden and mortality seen in this cohort of patients, this review aims to explore ...
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Rachel Khoo, Shirley Jansen Tags: ORIGINAL ARTICLE Source Type: research

Hyperbaric oxygen therapy and intermittent ischaemia in the treatment of chronic wounds
(Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Sarvnaz Sepehripour, Kiran Dhaliwal, Baljit Dheansa Tags: LETTER TO THE EDITOR Source Type: research

Calendar
(Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

News and views
(Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Tags: NEWS AND VIEWS Source Type: research

Another Year, Another Reflection
(Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Authors: Douglas Queen Tags: EDITORIAL Source Type: research

Issue Information
(Source: International Wound Journal)
Source: International Wound Journal - February 1, 2018 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Metataxonomic approach to decipher the polymicrobial burden in diabetic foot ulcer and its biofilm mode of infection
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - January 22, 2018 Category: Surgery Source Type: research