International Journal of Surgical Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Lipid-Rich Carcinoma of the Breast With Unusual Clinical and Histopathological Features
We report an unusual case of lipid-rich carcinoma with morphological and immunophenotypical features different from those of cases reported so far in the literature. The index case underscores the fact that there is no consensus with regard to the exact nature of this tumor. Hence, larger studies are needed to draw meaningful conclusions. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Gaspar, B. L., Kumar, M., Gupta, R., Garg, R., Singh, R., Vasishta, R. K. Tags: Case Reports Source Type: research

Is It a Dog? Is It a Sea Monster? Is it . . . ?
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Pandian, A., Pai, S. A. Tags: Images in Pathology Source Type: research

The Fragile Intraductal Lesions of the Prostate
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Acosta, A. M., Gallegos, M. Tags: Images in Pathology Source Type: research

Thyrosaurus Colloidus
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Marcus, A., Giorgadze, T. Tags: Images in Pathology Source Type: research

Mimics of Mammary Paget Disease: A Rogues Gallery
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Hoda, S., Cheng, E. Tags: Images in Pathology Source Type: research

Pseudofungi: A Diagnostic Pitfall
We report a patient with pseudofungi within a paratracheal lymph node, describe the morphologic findings, and discuss the differential diagnosis. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Lyapichev, K. A., Agarwal, A. N., Rosenberg, A. E., Chapman, J. R. Tags: Pitfalls in Pathology Source Type: research

Synovial Sarcoma With Myoid Differentiation
We describe a case of intraabdominal monophasic synovial sarcoma that immunohistochemically showed strong expression of smooth muscle actin and calponin but only very scanty cytokeratin, and which showed morphologic and immunohistochemical overlap with other spindle cell neoplasms that can arise at this site, such as gastrointestinal stromal tumor and myofibrosarcoma. As correct diagnosis is of clinical and prognostic importance, surgical pathologists should be aware of the potential for synovial sarcoma to occur at a variety of anatomic sites and of its spectrum of immunoreactivity. Synovial sarcoma should be in the diffe...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Qassid, O., Ali, A., Thway, K. Tags: Pitfalls in Pathology Source Type: research

Activating BRAF Mutations Detected in Mixed Hürthle Cell Carcinoma and Multifocal Papillary Carcinoma of the Thyroid Gland: Report of an Unusual Case and Review of the Literature
We present the case of a 69-year-old female who presented to the emergency department with a chief complaint of painful neck swelling. Imaging revealed a large right hemithyroid mass and a left hemithyroid nodule. Fine needle aspiration of the lesions and subsequent total thyroidectomy revealed a Hürthle cell carcinoma in the right lobe and bilateral multicentric papillary carcinoma foci, including 2 foci with a classical pattern and 1 encapsulated follicular variant in the isthmus. BRAF gene mutation analysis revealed V600E gene mutation in the classical variants of papillary carcinoma and in the Hürthle c...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Sinno, S., Choucair, M., Nasrallah, M., Wadi, L., Jabbour, M. N., Nassif, S. Tags: Molecular Surgical Pathology Source Type: research

Malignant Melanoma of the Nail Apparatus: A Fluorescence In Situ Hybridization Analysis of 7 Cases
Conclusions. RREB1 and CCND1 gains are common in nail apparatus melanoma as in most melanomas, and an increased number of genetic aberrations may be associated with a poorer prognosis, though the limited number of cases precludes definitive correlation. FISH appears to be a useful adjunct in the diagnosis of nail apparatus melanomas and improves diagnostic confidence even in the setting of unambiguous histomorphology. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Romano, R. C., Shon, W., Sukov, W. R. Tags: Original Articles Source Type: research

The Relationship Between Intracholecystic Papillary-Tubular Neoplasms and Invasive Carcinoma of the Gallbladder
Discussion. Some authors have reported that small intracholecystic exophytic lesions without high-grade dysplasia are considered to be inconsequential. However, there are not enough data concerning the features of large lesions with high-grade dysplasia and their prognoses. Our data suggest that cases with diffuse high-grade dysplasia and tubulopapillary/papillary growth pattern, large tumor size, and high Ki67 proliferation index should be studied for the presence of invasion. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Argon, A., Barbet, F. Y., Nart, D. Tags: Original Articles Source Type: research

Endometriosis of Extra-Abdominal Soft Tissues: A Tertiary Center Experience
While endometriosis, defined as the presence of endometrial tissue in extrauterine sites, is most frequently encountered within the peritoneal cavity, a small but significant proportion of cases occur at extra-abdominal soft tissue sites, particularly in relation to previous abdominal surgery. We reviewed the cases of endometriosis of soft tissue sites seen at a tertiary soft tissue center. All cases of extra-abdominal soft tissue endometriosis diagnosed at this institution over a 13-year period were reviewed, and clinical and pathologic findings were recorded. Forty-five patients had diagnoses of soft tissue endometriosis...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Wang, J., Strauss, D. C., Messiou, C., Thway, K. Tags: Original Articles Source Type: research

Neuroendocrine Carcinoma of the Cervix: Review of a Series of Cases and Correlation With Outcome
Conclusions. Histological review of a series of NECs has shown significantly reduced survival in those patients with confirmed NEC in comparison with those patients where a diagnosis of NEC was not confirmed. We propose morphological and immunohistochemical criteria for the diagnosis of cervical NEC; and discourage unqualified use of the term "small cell carcinoma" as this does not accurately convey the diagnosis of SCNEC. We urge pathologists to use the 2014 World Health Organization classification when reporting these tumors. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Ganesan, R., Hirschowitz, L., Dawson, P., Askew, S., Pearmain, P., Jones, P. W., Singh, K., Chan, K. K., Moss, E. L. Tags: Original Articles Source Type: research

Impact of Squamous Differentiation in Breast Carcinoma
This study attempted to review the impact of extent of squamous differentiation in 56 infiltrating duct carcinomas (IDC) with squamous differentiation (metaplastic squamous carcinomas [MSC]). Tumors showing 100% squamous elements were labeled as primary squamous carcinomas (PSC; n = 28) and compared with 28 MSC showing lesser squamous components. A clinicopathological comparison revealed that lymphovascular emboli were never seen in any PSC but were noted in 7/28 of other MSC, while perineural invasion was seen only in PSC and not in MSC. Nodal metastasis was significantly more in other MSC as opposed to PSC. Most MSC pres...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Pai, T., Shet, T., Desai, S., Patil, A., Nair, N., Parmar, V., Gupta, S., Budrukkar, A., Sarin, R., Badwe, R. Tags: Original Articles Source Type: research

Pseudohyperplastic Adenocarcinoma With Foamy Changes in Needle Prostate Biopsy and Prostatectomy
We report on the clinicopathological characteristics of 5 cases consisting predominantly of pseudohyperplastic and foamy adenocarcinomas. In several histological fields, this neoplasm mimicked hyperplastic nodules or prostatic adenosis because they showed the nodular pattern of the PHA and the inconspicuous cytological atypia of foamy gland carcinoma. Four cases had a Gleason score of 6. In the prostatectomies, the neoplasm was limited to the prostatic gland. The evolution has been favorable in all patients after 3 years of follow-up, on average. The cases reported herein demonstrate that PHA and foamy adenocarcinoma may b...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Arista-Nasr, J., Barranon-Martinez, I., Aguilar-Ayala, E., Bornstein, L., Trolle-Silva, A., Aleman-Sanchez, C. N., Martinez-Benitez, B. Tags: Original Articles Source Type: research

Papillary Renal Cell Carcinoma Arising in a Lymph Node Metastasis of a Testicular Teratoma: A Very Rare Occurrence
In conclusion, carcinomas of renal cell differentiation should be kept in mind as a rare form of TSM, especially in metastatic germ cell tumors. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - June 27, 2016 Category: Pathology Authors: Ozturk Sari, S., Ozluk, Y., Taskin, O. C., Polat, B., Ozturk, I., Ekenel, M., Kilicaslan, I., Bilgic, B. Tags: Case Reports Source Type: research