International Journal of Surgical Pathology International Journal of Surgical Pathology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

"Russell Body Gastroenterocolitis" in a Posttransplant Patient: A Case Report and Review of Literature
We report a case of a 44-year-old female with a history of diabetes mellitus, status post kidney and pancreas transplant who presented with multiple episodes of watery diarrhea associated with abdominal pain, nausea, and vomiting. Upper gastroendoscopic examination showed diffuse mild erythema in the gastric body and a clean-based duodenal ulcer. Lower gastroendoscopic examination was normal. Examination of multiple biopsies from duodenal, gastric, terminal ileum, and colonic mucosae revealed numerous plasma cells with abundant eosinophilic granular cytoplasm (Russell bodies) and eccentric nuclei, highlighted by PAS stain ...
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Muthukumarana, V., Segura, S., O'Brien, M., Siddiqui, R., El-Fanek, H. Tags: Case Reports Source Type: research

Low-Grade, Nonintestinal Nonsalivary Sinonasal Adenocarcinoma Associated With an Exophytic Schneiderian Papilloma: A Case Report
Sinonasal adenocarcinoma is a rare tumor of the head and neck accounting for 10% to 20% of all primary malignancies of the nose and paranasal sinuses. There tumors are classified as salivary, intestinal and nonintestinal, nonsalivary. Low-grade nonintestinal nonsalivary are rare tumors whose diagnosis is essentially that of exclusion. Here we present the first case of one such tumor associated with an exophyic Schneiderian papilloma. A 71-year-old retired aerospace engineer presented with a 1-year history of severe nasal obstruction. Endoscopy and compted tomography imaging demonstrated a polypoid lesion occupying his enti...
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Blumberg, J. M., Escobar-Stein, J., Vining, E. M., Prasad, M. L. Tags: Case Reports Source Type: research

Mucosal CD30-Positive T-Cell Lymphoproliferative Disorder Arising in the Oral Cavity Following Dental Implants: Report of the First Case
Mucosal CD30-positive T-cell lymphoproliferative disorder (CD30+ T-cell LPD) is a novel entity with unique clinicopathological features and an indolent behavior. Here we report the first case of mucosal CD30+ T-cell LPD arising in the oral cavity following dental implant. A 70-year-old woman presented with swelling and redness of the oral mucosa of right maxilla and left mandible surrounding dental implants that had been placed 8 years previously. Radiological examination revealed enhancing oral lesions and multiple cervical lymph nodes. Microscopic examination showed diffuse infiltration of large anaplastic cells with cha...
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Yoon, H.-J., Choe, J.-Y., Jeon, Y. K. Tags: Case Reports Source Type: research

"Giants in a Microcosm": Multinucleated Giant Cells Populating an Invasive Micropapillary Carcinoma of the Breast
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Marchio, C., Pietribiasi, F., Castiglione, R., Fusco, N., Sapino, A. Tags: Images in Pathology Source Type: research

Why Is Tinea an Annular Lesion With Centrifugal Growth?
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Chiriac, A., Brzezinski, P., Chiriac, A. E., Pinteala, T., Mares, M., Moldovan, C., Podoleanu, C., Cioloca, D., Arenas, R., Chang, P., Stolnicu, S. Tags: Images in Pathology Source Type: research

Intraneural Extension of Synovial Sarcoma: Exceptional, or Simply Underrecognized?
We describe a case arising extraneurally within the deep soft tissues of the forearm, which recurred and resulted in above-elbow amputation, revealing an unexpected finding of diffuse intraneural extension of tumor within a macroscopically normal major nerve. Despite macroscopic and microscopically clear soft tissue margins, the neoplasm had "traveled" a significant distance intraneurally to involve the neural resection margin. This feature does not appear to have been described before; it highlights the issue of whether intraneural spread of synovial sarcoma might have been previously underrecognized, and we discuss brief...
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Ng, W., Thway, K. Tags: Images in Pathology Source Type: research

Pericyte Antigens in Perivascular Soft Tissue Tumors
Discussion. In summary, pericyte marker expression is a ubiquitous finding in glomus tumor, myopericytoma, and angioleiomyoma. Malignant glomus tumor shows a comparative reduction in pericyte marker expression, which may represent partial loss of pericytic differentiation. Pericyte markers are essentially not seen in solitary fibrous tumor. The combination of αSMA, CD146, and PDGFRβ immunohistochemical stainings may be of utility for the evaluation of pericytic differentiation in soft tissue tumors. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Shen, J., Shrestha, S., Yen, Y.-H., Asatrian, G., Mravic, M., Soo, C., Ting, K., Dry, S. M., Peault, B., James, A. W. Tags: Original Articles Source Type: research

Significance of Vascular Endothelial Growth Factor (VEGF)-C and VEGF-D in the Progression of Cutaneous Melanoma
Conclusions. Our findings show the significance of VEGF-C in tumor cells in the induction of intratumoral and peritumoral lymphangiogenesis. This study suggests that both VEGF-C and VEGF-D in tumor cells promote lymph node metastasis, and that the immunohistochemical analysis of expression can be a useful tool for predicting clinical behavior of cutaneous melanoma. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Spiric, Z., Eri, Z., Eric, M. Tags: Original Articles Source Type: research

Which Lymph Nodes Contain Metastases in Colon Cancer Patients? A Retrospective Histopathological Evaluation of 156 Patients
Conclusion. In our study, the N-stage was determined by the 5 largest nodes in almost all specimens. The chance of finding a small tumor-positive node when the larger ones were clean was very small. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: da Costa, D. W., Vrouenraets, B. C., Witte, B. I., van Dekken, H. Tags: Original Articles Source Type: research

Average Weight of Seminal Vesicles: An Adjustment Factor for Radical Prostatectomy Specimens Weighed With Seminal Vesicles
The International Society of Urological Pathology in 2010 recommended weighing prostates without seminal vesicles (SV) to include only prostate weight in prostate-specific antigen (PSA) density (PSAD) calculation, because SV do not produce PSA. Large retrospective cohorts exist with combined weight recorded that needs to be modified for retrospective analysis. Weights of prostates and SV were separately recorded in 172 consecutive prostatectomies. The average weight of SV and proportion of prostate weight from combined weight were calculated. The adjustment factors were then validated on databases of 2 other institutions. ...
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Tjionas, G. A., Epstein, J. I., Williamson, S. R., Diaz, M., Menon, M., Peabody, J. O., Gupta, N. S., Parekh, D. J., Cote, R. J., Jorda, M., Kryvenko, O. N. Tags: Original Articles Source Type: research

Clinicopathologic and Immunophenotypic Features of Primary Intestinal Extranodal NK/T-Cell Lymphoma, Nasal Type
Primary intestinal extranodal NK/T-cell lymphoma, nasal type, is an extremely rare type of lymphoma with poor prognosis, and early diagnosis is challenging. Here we have investigated the clinicopathologic features and immunophenotypes of primary intestinal extranodal NK/T cell lymphomas, nasal type, in 10 Chinese patients. Complete staging data showed that 1 patient had stage I disease, 7 had stage II disease, and 2 had stage III disease. Eight of 10 (80%) patients had lymphadenopathy and none had bone marrow involvement. All the patients had a low International Prognostic Index (IPI) score (<3) at presentation. The med...
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Fang, J.-C., Xia, Z.-X., Wang, C.-N., Li, Z. Tags: Original Articles Source Type: research

Evaluation of Molecular and Immunohistochemical Adjunct Modalities in the Diagnosis of Soft Tissue Neoplasms
The accurate diagnosis of soft tissue neoplasms has crucial therapeutic and prognostic importance. There is frequent morphologic overlap between entities, and ancillary modalities are used in the vast majority of diagnoses. Immunohistochemistry is rapid and inexpensive, and in addition to the older markers that mainly detected cytoplasmic proteins, antibodies can indirectly detect tumor-specific genetic and molecular abnormalities. The use of molecular diagnostic techniques is now widespread, with molecular services often integrated into routine histopathology laboratories; as their cost and turnaround times begin to paral...
Source: International Journal of Surgical Pathology - November 9, 2015 Category: Pathology Authors: Mourtzoukou, D., Fisher, C., Thway, K. Tags: Original Articles Source Type: research

Novel Pathologic Finding of Digital Soft Tissue Chondroma in a Child: A Case Report and Review of Literature
We report the case of a 9-year-old female that presented with a tender digital mass 6 months following a minor hand injury. After an extensive workup, the mass was surgically excised and diagnosed as an STC. Our case is the first to identify a digital STC in a pediatric patient and expands on the pathologic differential diagnosis. While the true incidence in the pediatric population is unknown, STC should be included in the differential diagnosis when any patient, adult or child, presents with a digital mass. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 31, 2015 Category: Pathology Authors: Rubin, T., Schwartz, A., Fornari, E., Schulz, J. Tags: Case Reports Source Type: research

Ectopic Pancreas Presenting as a Solid Mediastinal Mass
In this report, we present a case of ectopic pancreas appearing as a large solid mass in the anterior mediastinum of a 17-year-old male patient. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 31, 2015 Category: Pathology Authors: Koh, H. M., Chang, J. W., Jeong, S. Y., Hyun, C. L., Kim, Y. S., Jang, B. G., Maeng, Y. H. Tags: Case Reports Source Type: research

Desmoid Tumor of the Pancreas: Case Report and Review of a Rare Entity
We present a case of a 63-year-old woman who complained of abdominal pain, and a contrast-enhanced computed tomography scan revealed a well-circumscribed tumor in the pancreatic tail, measuring 5.1 cm. A left-sided, spleen-preserving pancreatic resection was performed, and pathological analysis showed a mesenchymal tumor. The diagnosis of a pancreatic desmoid tumor was made based on the characteristic morphology and the immune phenotype of the tumor. The English-language literature on pancreatic desmoid tumors was reviewed. In total, 16 previous cases were identified. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 31, 2015 Category: Pathology Authors: Gerleman, R., Mortensen, M. B., Detlefsen, S. Tags: Case Reports Source Type: research