Mullerian Adenosarcoma Arising in a Subserosal Adenomyoma
Müllerian adenosarcomas most commonly arise in the uterine corpus from the eutopic endometrium. Occasionally, they arise in the cervix, vagina, broad and round ligaments, and ovaries and rarely in extragenital sites, usually in association with endometriosis. The authors report a rare case of extraendometrial, intramural adenosarcoma of low grade arising from a subserosal adenomyoma in a 46-year-old woman who presented with vaginal bleeding. No evidence of eutopic endometrial origin was identified; the adenosarcoma showed only limited myometrial invasion and no serosal involvement. Because of its subserosal location, ...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Elshafie, M., Rahimi, S., Ganesan, R., Hirschowitz, L. Tags: Case Reports Source Type: research

Unicystic Mucoepidermoid Carcinoma Presenting as a Salivary Duct Cyst
A cystic swelling in the parotid gland should lead to a differential diagnosis that includes benign cystic lesion of the gland, benign tumors that are frequently associated with cystic degeneration or entirely cystic de novo, or even a malignant neoplasm. The case presented is that of a cystic parotid swelling of 2 years’ duration in a 52-year-old female patient. The clinical differentials in the present case were reviewed and were entirely different from the final histological diagnosis of low-grade mucoepidermoid carcinoma. The uniqueness of this case is the very rare unicystic presentation of the lesion. The autho...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Qannam, A., Bello, I. O., Al-Kindi, M., Al-Hindi, M. Tags: Case Reports Source Type: research

Primary Breast Amyloidosis Presenting Solely as Nonpalpable Microcalcifications: A Case Report With Review of the Literature
Primary breast amyloidosis is a rare disease and usually occurs as unilateral or bilateral palpable masses. Primary breast amyloidosis presenting solely as microcalcifications is extremely rare. The authors report a case of a 73-year-old woman with persistent suspicious microcalcifications without palpable mass. The diagnosis was established by the presence of an amorphous and eosinophilic material that was positive for Congo red and dichroic under polarized light. Paraffin immunohistochemistry revealed the presence of kappa light chains (AL-type amyloidosis). The amyloid deposits were associated with microcalcifications. ...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Ngendahayo, P., Faverly, D., Herin, M. Tags: Case Reports Source Type: research

Epiphyseal Ewing Sarcoma: First Reported Case With Molecular Confirmation
Ewing sarcoma is the second most common pediatric malignant bone neoplasm after osteosarcoma. Ewing sarcoma comprises "small, round, blue-cell" tumors thought to arise from neural crest cells. The authors report the case of a 14-year-old boy that presented with a nonpainful circumscribed lesion. The radiographs showed a lytic lesion at the tibial epiphysis with a large soft tissue mass, best depicted in the magnetic resonance imaging scan that suggested an aggressive lesion. A needle biopsy of the lesion was performed. The diagnosis of Ewing sarcoma was made based on microscopic, immunohistochemical, polymerase c...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Perez-Gonzalez, Y., Garcia-Esparza, E., Conde, E., Azorin, D. Tags: Case Reports Source Type: research

Minute Type I Gastric Carcinoid With Regional Lymph Node Metastasis
This study reports a diminutive (8 mm) gastric carcinoid, limited to the superficial layer of the submucosa (sm1), with no angiovascular invasion, but with a high Ki-67 index (7%) and an involved perigastric lymph node. The aggressive behavior of this lesion ends the previous believe that small and superficial type I gastric carcinoids do not metastasize. This case also indicates that better parameters are necessary to evaluate the malignant potential of these lesions and presents a further support to the value of 2010 World Health Organization classification of gastrointestinal neuroendocrine tumors. (Source: Internationa...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Lupinacci, R. M., Dias, A. R., Mello, E. S., Kondo, A. Tags: Case Reports Source Type: research

Primary Cutaneous Hydroa Vacciniforme-Like Lymphoma With Indolent Clinical Course: Report of Two Cases and Review of Literature
This report presents 2 cases of primary cutaneous HV-like lymphoma with unusual indolent clinical course and favorable prognosis during the follow-up periods of 2 and 3 years, respectively. Both patients presented with erythema, papulovesicles, scars, ulcerations, and edema on the face and extremities. Skin biopsies revealed epidermal vesicle with small- to medium-sized atypical lymphoid cells infiltrating in the dermis and subcutis. The lymphoid cells were strongly immunoreactive to CD8 and CD56. The Epstein–Barr virus genomes were also found in both skin biopsies. By genetic analysis, one of patients showed T-cell ...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Li, Y., Chen, X.-h., Tian, X.-y., Li, B., Li, Z. Tags: Case Reports Source Type: research

Cellular Metanephric Stromal Tumor in a Postmenopausal Woman: A Case Report With Review of the Literature
Metanephric stromal tumor (MST) of the kidney is a rare pediatric neoplasm which has rarely been reported in adults. The authors present a case of MST, cellular type, an unreported variant, in a 56-year-old postmenopausal woman. The 9.0-cm tumor was solid, unencapsulated, and well circumscribed, with a firm homogeneous cut surface. The tumor was purely stromal with dense spindle-cell proliferations displaying prominent schwannoma-like architecture, intratumoral angiodysplasia, and entrapped native renal tubules with "onion-skin" tumor collarettes. The tumor stroma expressed CD34, estrogen, and progesterone and di...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Chaudhri, A. A., Lee, L., Das, K. Tags: Case Reports Source Type: research

Mucinous Cystadenoma of the Retroperitoneum
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Bosisio, F. M., Estevez, S., Segura, J. Tags: Images in Pathology Source Type: research

The Face of the Devil Finally Revealed
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: AbdullGaffar, B. Tags: Images in Pathology Source Type: research

Finding Apotropaic Images in Dermatopathology
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Aneiros-Fernandez, J., Requena, L., Dulcey, I., Nogales, F. F. Tags: Images in Pathology Source Type: research

Equine Pathology for the Surgical Pathologist
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Coyne, J. D. Tags: Images in Pathology Source Type: research

The Punch and Judy Show Visits Histopathology
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Coyne, J. Tags: Images in Pathology Source Type: research

Caricatures of the Famous in Surgical Pathology
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Coyne, J. D. Tags: Images in Pathology Source Type: research

Dilated High Endothelial Venules in Lymph Nodes Simulating Metastatic Thyroid Carcinoma
We present a case in which such a situation arose. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Estevez, S., Bosisio, F. M. Tags: Pitfalls in Pathology Source Type: research

Podoplanin and E-cadherin Expression in Preoperative Incisional Biopsies of Oral Squamous Cell Carcinoma Is Related to Lymph Node Metastases
Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases and, moreover, in planning the proper therapeutic procedures before surgery. To this end, immunohistochemical expressions of both E-cadherin and podoplanin were evaluated on preoperative incisional biopsies of OSCC from 102 patients. The probability to have or develop metastases was very low when high E-cadher...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Foschini, M. P., Leonardi, E., Eusebi, L. H., Farnedi, A., Poli, T., Tarsitano, A., Cocchi, R., Marchetti, C., Gentile, L., Sesenna, E., Marucci, G., Montebugnoli, L. Tags: Original Articles Source Type: research

Evaluation of Biomarkers in Multifocal/Multicentric Invasive Breast Carcinomas
Conclusion. Regardless of the similarity in tumor morphology or grade, a small number of cases included foci that exhibited different tumor marker expression, which might affect the treatment strategy. Therefore, our results suggest that the evaluation of tumor markers in different foci should be considered in MF/MC tumors for accurate treatment strategies. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Pekmezci, M., Szpaderska, A., Osipo, C., Ersahin, C. Tags: Original Articles Source Type: research

SALL4 and SF-1 Are Sensitive and Specific Markers for Distinguishing Granulosa Cell Tumors From Yolk Sac Tumors
In this study, the authors performed immunohistochemical stains for SALL4 and steroidogenic factor-1 (SF-1) on 27 cases of yolk sac tumors and 24 granulosa cell tumors. Nuclear stains for both antibodies were considered as positive and the intensity of staining was graded as negative, weak, moderate, and strong. All the yolk sac tumors were positive for SALL4 (100%) with moderate to strong grade staining and negative for SF-1 (100%). In contrast, all the granulosa cell tumors were positive for SF-1 (85% moderate to strong grade staining and 15% weak staining) and negative for SALL4 (100%). The difference was significant (P
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Bai, S., Wei, S., Ziober, A., Yao, Y., Bing, Z. Tags: Original Articles Source Type: research

Tumor-Infiltrating Mast Cells in Colorectal Cancer as a Poor Prognostic Factor
The purpose of this study is to investigate the clinical/prognostic significance of tumor-infiltrating mast cells (TIMs) in patients with colorectal cancer (CRC). TIM infiltration in 325 stage I to III CRC specimens was detected by immunohistochemistry. The optimal cutpoint of TIM density was assessed by the X-tile program. TIM infiltration in CRC was significantly higher than in normal colorectal tissues. According to the X-tile program, the cutpoint for high TIM infiltration in CRC was determined when TIM density was more than 8.0 per high-power field. Correlation analysis between TIM density and clinicopathological vari...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Wu, X., Zou, Y., He, X., Yuan, R., Chen, Y., Lan, N., Lian, L., Wang, F., Fan, X., Zeng, Y., Ke, J., Wu, X., Lan, P. Tags: Original Articles Source Type: research

Clinicopathological Significance of NUT Rearrangements in Poorly Differentiated Malignant Tumors of the Upper Respiratory Tract
This study investigated the clinicopathological significance of NUT rearrangements in poorly differentiated malignant tumors (PDMTs) of the upper-respiratory tract (URT) in China. The clinical and pathological features of 155 PDMTs of the URT were reviewed. Epstein-Barr virus (EBV)-encoded RNA and NUT were investigated by in situ hybridization and immunohistochemistry (IHC), respectively. NUT-positive cases were examined by fluorescence in situ hybridization (FISH) and immunohistochemical staining with a set of cytokeratins (CKs) and neuroendocrine markers. One case was observed by transmission electron microscopy. Four ca...
Source: International Journal of Surgical Pathology - March 20, 2013 Category: Pathology Authors: Fang, W., French, C. A., Cameron, M. J., Han, Y., Liu, H. Tags: Original Articles Source Type: research

Abundant Hepatic Gaucher-Like Cells Following Chemotherapy and Bone Marrow Transplantation for Hematologic Malignancy: Report of Two Cases
Cells with a resemblance to Gaucher cells, sometimes called pseudo-Gaucher cells, are seen in the bone marrow of some patients with hematologic malignancy or anemia. These cells are derived from cells of the monocytic lineage but do not show the characteristic inclusions of true Gaucher cells when examined by electron microscopy. Large numbers of Gaucher-like cells were found in the livers at autopsy of 2 patients with hematologic malignancy treated with chemotherapy and bone marrow transplant. Knowledge of this phenomenon may be useful in the interpretation of liver biopsy done on a patient with bone marrow transplant. (S...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Stenzel, P., Weeks, D. A. Tags: Case Reports Source Type: research

Neuroendocrine Tumors of the Submandibular Gland: Literature Review and Report of a Case
Primary salivary neuroendocrine neoplasms are extremely rare, with only 1 case of carcinoid tumor and 7 cases of primary large-cell neuroendocrine carcinomas having been reported. Salivary small-cell neuroendocrine carcinomas are more frequent, accounting for less than 2% of all salivary malignancies. In addition to a literature review on the subject, the authors describe a rare case of malignant intermediate-grade neuroendocrine tumor of the submandibular gland. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Petrone, G., Santoro, A., Angrisani, B., Novello, M., Scarano, E., Rindi, G., Lauriola, L. Tags: Case Reports Source Type: research

Squamous Metaplasia of the Peritoneum: Report of a Case
This report presents a case of fully developed, mature peritoneal squamous metaplasia in an 85-year-old woman who underwent surgery because of small bowel perforation leading to diffuse peritonitis. This rare incidental finding almost always occurs in the background of chronic peritoneal irritation as a response to mesothelial injury. Squamos peritoneal metaplasia should not be interpreted as metastatic squamous cell carcinoma. The most important distinguishing criteria are the lack of nuclear atypia, mitoses, necrosis, and desmoplastic stromal response. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Mrklic, I., Bendic, A., Pogorelic, Z., Karaman, I., Glavina Durdov, M., Druzijanic, N., Tomic, S. Tags: Case Reports Source Type: research

Unmasked: When a Clinically Malignant Disease Turns Out Infectious. A Rare Case of Tularemia
This article reports on a 62-year-old man, who presented with cervical mass and rather nonspecific symptoms. The medical history and clinical workup initially favored a malignant disease such as a carcinoma of unknown primary as the underlying cause. Eventually, the patient was diagnosed with a granulomatous lymphadenitis caused by Francisella tularensis subsp holarctica. Tularemia is a rare disease in Western Europe and can present in multiple ways encompassing almost asymptomatic infections and fatal disease. A rapid diagnosis is often hampered by nonspecific symptoms and the generally low prevalence and incidence of thi...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Bulut, O. C., Dyckhoff, G., Splettstoesser, W., Nemeth, J., Klauschen, F., Penzel, R., Plinkert, P. K., Simon, C., Weichert, W., Stenzinger, A. Tags: Case Reports Source Type: research

Signet-Ring-Cell Carcinoma of Stomach Metastatic to the Bladder: A Case Report With Cytological and Histological Correlation and Literature Review
Conclusion. Bladder involvement by a secondary tumor is very rare, and a SRC carcinoma metastatic to the bladder, albeit extremely rare, should be considered in the differential diagnosis. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Vigliar, E., Marino, G., Matano, E., Imbimbo, C., Rossella, D. C., Insabato, L. Tags: Case Reports Source Type: research

Non-Small Cell Bronchial Carcinoma Metastasizing into a Prolactin-Producing Pituitary Adenoma
This study presents the case of a 66-year-old man with a non–small cell bronchial carcinoma that metastasized into a prolactin (PRL)-producing pituitary adenoma. The pituitary adenoma cells were immunoreactive for PRL and vascular endothelial growth factor (VEGF). It is hypothesized that VEGF and PRL played a role in the development of metastasis within the adenoma. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Rotondo, F., Kovacs, K., Macdonald, R. L., Prud'homme, G. J., Latta, E., Munoz, D. Tags: Case Reports Source Type: research

Primary Ewing's Sarcoma/Primitive Neuroectodermal Tumor (ES/PNET) of the Penis: A Report of an Extraordinarily Unusual Site and a Literature Review of Extraskeletal Ewing's Sarcoma
This study reports a case of a 28-year-old man with primary EES/PNET of the penis. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Ma, Z., Brimo, F., Zeizafoun, N. Tags: Case Reports Source Type: research

Human Papillomavirus Type 16 DNA Detected in Pulmonary Metastases From a Penile Squamous Cell Carcinoma: A Case Study
This report describe the case of a patient presenting with pulmonary metastases from a penile cancer, where the presence of the human papillomavirus (HPV) type 16 DNA both in the primary tumor and in the distant metastases confirmed the spreading of the disease, ruling out a possible primary lung squamous cell carcinoma. Indeed, according to the findings, the HPV genotyping test might help in the identification of metastatic disease from anogenital malignancies or other HPV-related cancers. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Lorenzon, L., Benevolo, M., Visca, P., Venturo, I., Filippetti, M., Piro, F. R., Rollo, F., Vocaturo, A. Tags: Case Reports Source Type: research

Multinodular Reticular Schwannoma in the Head and Neck Region: A Potential Diagnostic Pitfall
This report describes a case occurring in the masticator space, accompanied by focal erosion of the orbital floor, clinically and radiologically worrisome for malignancy. The 26-year-old man presented with facial swelling for 3 month. The tumor shows a multinodular appearance, with dense lymphoplasmacytic infiltrates in the fibrous septa. The tumor nodules are composed of plump spindle cells disposed in a reticular pattern. The diagnosis is confirmed by strong positive staining for S100 protein. The differential diagnoses of reticular schwannoma in the soft tissues of head and neck region are different from those in the ga...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Lau, P. P. L., Yau, D. T. W., Lau, W. H., Mak, L. S., Chan, J. K. C. Tags: Case Reports Source Type: research

Benign Looking Giant Cell Component in Dedifferentiated Chondrosarcoma: Benign or Malignant? A Case Report
Dedifferentiated chondrosarcomas (DDCS) account for approximately 10% of all chondrosarcoma cases and its 5-year survival is only 10%. The dedifferentiated components of DDCS could be osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma. In this article, the authors report a rare case of DDCS in a 19-year-old female, in which the dedifferentiated component showed a close histological resemblance to a giant cell tumor of bone. Radiological diagnosis revealed an expansive osteolytic lesion in the epiphysis of right proximal humerus, which also extended to the diaphysis with irregular calcification and focal cortica...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Huang, J., Jiang, Z., Yang, Q., Zhang, H. Tags: Case Reports Source Type: research

"Tire-Bouchon" for Vintage Colloid
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Bosisio, F. M., Estevez, S. Tags: Images in Pathology Source Type: research

The Vigilant Eye
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Giorgadze, T. A. Tags: Images in Pathology Source Type: research

Perianal Pulse Granuloma
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Pilatti, A., Patriarca, C. Tags: Images in Pathology Source Type: research

Hyaline Globules in a Nasopharyngeal Carcinoma
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Lee, L.-y., Kuo, T.-t. Tags: Images in Pathology Source Type: research

Sinonasal Teratocarcinosarcoma: A Clinical and Pathological Analysis
The goal of this study was to assess the pathological and differential diagnoses of sinonasal teratocarcinosarcoma (SNTCS) in order to ultimately improve the diagnosis and treatment of this rare disease. Data from 2 cases of sinonasal teratocarcinosarcoma from the Wuxi People’s Hospital (China) were analyzed. The clinical presentation for these patients consisted of nasal obstruction, epistaxis, and headache. On further physical examination, the presence of a polypoid mass was identified and, despite surgery and radiotherapy, both cases experienced recurrence. Histologically, the tumors showed a heterogeneous mixture...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Yang, S., Sun, R., Liang, J., Zhou, Z., Zhou, J., Rui, J. Tags: Original Articles Source Type: research

Ultrastructurally Confirmed Myofibrosarcoma: A Series of 10 New Cases, With a Discussion on Diagnostic Criteria
Some view ultrastructure as key to myofibrosarcoma diagnosis, whereas others argue that electron microscopy is too little used in contemporary practice to be considered an important diagnostic tool. These views are discussed in the context of 10 ultrastructurally confirmed cases of myofibrosarcoma, some occurring at rare sites such as skin and penis. Patient age ranged from 21 to 83 years, with a 6:4 male to female ratio. Size ranged from 2 to 7.5 cm and all had infiltrative margins. Histologically, all consisted of variably cellular fascicles of spindle cells with mild to moderately pleomorphic nuclei, small punctate nucl...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Shenjere, P., Eyden, B., Banerjee, S. S., Chakrabarty, B., Shanks, J. H., Sikand, K. A., Menasce, L. P. Tags: Original Articles Source Type: research

Hybrid Schwannoma/Perineurioma: Report of 10 Chinese Cases Supporting a Distinctive Entity
This article describes 10 cases of hybrid schwannoma/perineurioma arising in diverse anatomic locations. They all occurred in adult patients (age range 27-81 years, median 35 years) with a marked female predominance (2 males and 8 females). Of the 10 tumors, 7 were situated in the subcutis of trunk (n = 3), extremities (n = 2), neck (n = 1), and labium majus (n = 1) and 3 in the submucosa of nasal cavity, sigmoid colon, and rectum, respectively. Histologically, they were composed of intimately admixed plump spindle cells and elongated slender spindle cells forming storiform, lamellar or fascicular architecture. By immunohi...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Yang, X., Zeng, Y., Wang, J. Tags: Original Articles Source Type: research

Dedifferentiated Liposarcoma With Lipoma-Like Well-Differentiated Liposarcoma: Clinicopathological Study of 30 Cases, With Particular Attention to the Comingling Pattern of Well- and Dedifferentiated Components: A Proposal for Regrouping of the Present Subclassification of Well-Differentiated Liposarcoma and Dedifferentiated Liposarcoma
Dedifferentiated liposarcoma (DDL) is defined as nonlipogenic sarcoma, with an abrupt transition from coexisting well-differentiated liposarcoma (WDL). However, intermingled transition in a mosaic pattern between WDL and DDL is not infrequently encountered. Here, the authors review clinicopathological features of 30 cases of DDL associated with lipoma-like WDL. Histological examination revealed 20 tumors that showed an abrupt transition between WDL and DDL. Among these, 13 tumors showed high-grade spindle-cell sarcoma having histological features of unclassified malignant fibrous histiocytoma (MFH)-like sarcoma (high-grade...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Iwasa, Y., Nakashima, Y. Tags: Original Articles Source Type: research

Mixed Gastric Carcinoma With Intestinal and Cribriform Patterns: A Distinctive Pathologic Appearance Associated With Poor Prognosis in Advanced Stages and a Potential Mimicker of Metastatic Breast Carcinoma
This article describes a peculiar pattern of gastric adenocarcinoma, previously unreported, that combines intestinal type adenocarcinoma with areas of cribriform pattern that resembles both architectural and cytological in situ ductal carcinoma of the breast and to the best of the authors’ knowledge, there are no earlier reports of this pattern in the stomach, which has been named "gastric carcinoma with cribriform component (CGA). The authors analyzed 12 cases of intestinal type adenocarcinoma with areas at least 20% of cribriform pattern (range from 20% to 90%) that was present in 9% of intestinal type gastric...
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Lino-Silva, L. S., Salcedo Hernandez, R. A., Molina-Frias, E. Tags: Original Articles Source Type: research