Is acute reperfusion therapy safe in acute ischemic stroke patients who harbor unruptured intracranial aneurysm?
ConclusionOur findings suggest that neither intravenous thrombolysis nor combination of intravenous and intra‐arterial thrombolysis increases the risk of aneurysmal hemorrhage in acute ischemic stroke patients who harbor unruptured intracranial aneurysms less than 10 mm in diameter. Their listing in exclusion criteria for intravenous thrombolysis should be reconsidered to assure appropriate use of acute reperfusion therapy in this group of patients. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 17, 2015 Category: Neurology Authors: Ashkan Mowla, Karanbir Singh, Sandhya Mehla, Mohammad K. Ahmed, Peyman Shirani, Haris Kamal, Chandan Krishna, Robert N. Sawyer, Marilou Ching, Adnan H. Siddiqui, Elad I. Levy, Kenneth V. Snyder, Annemarie Crumlish, L. N. Hopkins Tags: Research Source Type: research

Adverse outcome after incident stroke hospitalization for Indigenous and non‐Indigenous Australians in the Northern Territory
ConclusionIndigenous stroke patients have higher prevalence of comorbidities than non‐Indigenous stroke patients, which explained part of the disparity in both case fatality and long‐term survival but did not explain the disparity in stroke recurrence at all. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 9, 2015 Category: Neurology Authors: Vincent YF. He, John R. Condon, Jiqiong You, Yuejen Zhao, James N. Burrow Tags: Research Source Type: research

Discharge educational strategies for reduction of vascular events (DESERVE): design and methods
DiscussionDESERVE will evaluate whether a novel discharge education strategy leads to improved risk factor control in a racially diverse population. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 9, 2015 Category: Neurology Authors: Aaron S. Lord, Heather M. Carman, Eric T. Roberts, Veronica Torrico, Emily Goldmann, Koto Ishida, Stanley Tuhrim, Joshua Stillman, Leigh W. Quarles, Bernadette Boden‐Albala Tags: Protocol Source Type: research

A collaborative sequential meta‐analysis of individual patient data from randomized trials of endovascular therapy and tPA vs. tPA alone for acute ischemic stroke: ThRombEctomy And tPA (TREAT) analysis: statistical analysis plan for a sequential meta‐analysis performed within the VISTA‐Endovascular collaboration
DiscussionThis collaborative meta‐analysis of individual participant data from randomized trials of endovascular therapy vs. control in conjunction with intravenous thrombolysis will demonstrate the efficacy and generalizability of endovascular therapy with intravenous thrombolysis as a concomitant medication. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 9, 2015 Category: Neurology Authors: Rachael L. MacIsaac, Pooja Khatri, Martin Bendszus, Serge Bracard, Joseph Broderick, Bruce Campbell, Alfonso Ciccone, Antoni Dávalos, Stephen M. Davis, Andrew Demchuk, Hans‐Christoph Diener, Diederik Dippel, Geoffrey A. Donnan, Jens Fiehler, David Fior Tags: Protocol Source Type: research

The efficacy of Wii ‐based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial
International Journal of Stroke,Volume 10, Issue 8, Page 1253-1260, December 2015. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Authors: Penelope A. McNulty , Angelica G. Thompson ‐Butel , Steven G. Faux , Gaven Lin , Pesi H. Katrak , Laura R. Harris , Christine T. Shiner Source Type: research

Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology
International Journal of Stroke,Volume 10, Issue 8, Page 1247-1252, December 2015. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Authors: Chuanhui Dong , David Della ‐Morte , Digna Cabral , Liyong Wang , Susan H. Blanton , Chaturvedi Seemant , Ralph L. Sacco , Tatjana Rundek Source Type: research

The efficacy of Wii ‐based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial
International Journal of Stroke,Volume 10, Issue 8, Page 1253-1260, December 2015. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Source Type: research

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International Journal of Stroke,Volume 10, Issue 8, Page 1247-1252, December 2015. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Source Type: research

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International Journal of Stroke,Volume 10, Issue 8, Page 1253-1260, December 2015. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Source Type: research

Effect of helicopter transport on neurological outcomes in a mouse model of embolic stroke with reperfusion: AIR‐MICE pilot study
ConclusionsThis study shows that helicopter emergency medical services do not have an inherent adverse effect on outcome in a mouse model of ischemic stroke with reperfusion. These results endorse the safety of the practice of using helicopter emergency medical services in stroke patients. The observed potential synergistic effect of helicopter‐induced factors, such as vibration and changes in altitude, with reperfusion merits further exploration in animal experimental models and in stroke patients. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Authors: Enrique C. Leira, Asgar Zaheer, Thomas Schnell, James C. Torner, Heena M. Olalde, Andrew A. Pieper, Santiago Ortega‐Gutierrez, Nandakumar Nagaraja, Nancy L. Marks, Harold P. Adams Tags: Research Source Type: research

Stroke preparedness in children: translating knowledge into behavioral intent: a systematic review and meta‐analysis
ConclusionChildren are a potentially attractive target population for improvement in stroke knowledge and behavioral intent, both in the short and long term. Our findings may support the implementation of large‐scale stroke educational initiatives targeting children. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Authors: Cassandra Ottawa, Luciano A. Sposato, Fadl Nabbouh, Gustavo Saposnik, Tags: Systematic Review Source Type: research

Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology
ConclusionOur findings suggest that polymorphisms in SIRT6/UCP1 genes may be important for increased carotid plaque burden and echodensity, but translation of these findings to an individual risk of cerebrovascular events needs further investigation. Significant associations of rs1430583 in women, rs12363280 in men, and rs1685354 in those with dyslipidemia also deserve further investigations. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Authors: Chuanhui Dong, David Della‐Morte, Digna Cabral, Liyong Wang, Susan H. Blanton, Chaturvedi Seemant, Ralph L. Sacco, Tatjana Rundek Tags: Research Source Type: research

The correlation between admission blood glucose and intravenous rt‐PA‐induced arterial recanalization in acute ischemic stroke: a multi‐centre TCD study
ConclusionHyperglycemia is associated with low rate of complete recanalization and poor clinical outcome in intravenous recombinant tissue‐plasminogen activator‐treated patients. Further studies are needed to evaluate whether lowering hyperglycemia is beneficial in the management of acute stroke patients. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Authors: Maher Saqqur, Ashfaq Shuaib, Andrei V. Alexandrov, Joseph Sebastian, Khurshid Khan, Ken Uchino Tags: Research Source Type: research

The efficacy of Wii‐based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial
ConclusionsThis study demonstrates that Wii‐based Movement Therapy is an effective upper limb rehabilitation poststroke with high patient compliance. It is as effective as modified Constraint‐induced Movement Therapy for improving more affected upper limb movement and increased independence in activities of daily living. (Source: International Journal of Stroke)
Source: International Journal of Stroke - September 1, 2015 Category: Neurology Authors: Penelope A. McNulty, Angelica G. Thompson‐Butel, Steven G. Faux, Gaven Lin, Pesi H. Katrak, Laura R. Harris, Christine T. Shiner Tags: Research Source Type: research