International Journal of STD and AIDS This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Developing new models of shared primary and specialist HIV care in the UK: a survey of current practice
We describe contemporary models of shared HIV care in relevant developed world settings to inform future shared HIV care in the UK. An interview survey of key informants was used to explore experiences and models of shared care, and identify promoting and inhibiting factors. We interviewed ten key informants from six shared care models. There were three broad categories of shared care, with varying degrees of GP involvement. Strong clinical leadership in primary care, good professional relationships and communication, and tailored GP training were facilitators. Barriers included stigma, confidentiality concerns, and low pr...
Source: International Journal of STD and AIDS - June 6, 2016 Category: Global & Universal Authors: Hutchinson, J., Sutcliffe, L. J., Williams, A. J., Estcourt, C. S. Tags: Original research articles Source Type: research

Preparing for pre-exposure prophylaxis: perceptions and readiness of Canadian pharmacists for the implementation of HIV pre-exposure prophylaxis
The objective of the study was to determine Canadian HIV pharmacists’ support for PrEP and to identify current barriers to promoting PrEP. Canadian pharmacists with experience in HIV care were invited to complete an online survey about their experiences, opinions, and learning needs regarding PrEP from December 2012 to January 2013. Among the 59 surveys received, 48 met criteria for final analysis. Overall, 33 (69%) respondents would provide education positively supporting the use of PrEP and 26 (54%) believed Health Canada should approve PrEP for use in Canada. Familiarity with the concept of PrEP and practice chara...
Source: International Journal of STD and AIDS - June 6, 2016 Category: Global & Universal Authors: Yoong, D., Naccarato, M., Sharma, M., Wilton, J., Senn, H., Tan, D. H. Tags: Original research articles Source Type: research

2016 European guideline on donovanosis
Donovanosis is a rare sexually transmitted infection now mainly seen in sporadic cases in Papua New Guinea, South Africa, India, Brazil and Australia. The causative organism is Calymmatobacterium granulomatis, though a proposal has been put forward that the organism be reclassified as Klebsiella granulomatis comb nov. The incubation period is approximately 50 days with genital papules developing into ulcers that increase in size. Four types of lesions are described – ulcerogranulomatous, hypertrophic, necrotic and sclerotic. The diagnosis is usually confirmed by microscopic identification of characteristic Donovan bo...
Source: International Journal of STD and AIDS - June 6, 2016 Category: Global & Universal Authors: OFarrell, N., Moi, H. Tags: Guidelines Source Type: research

Uveitis secondary to leishmaniasis immune reconstitution syndrome in a HIV-positive patient
We describe the case of a HIV-positive patient treated for visceral leishmaniasis who developed uveitis as part of a leishmaniasis immune reconstitution syndrome. Visceral leishmaniasis is increasingly found in HIV-positive adults. Its ophthalmic manifestations can range from relatively minor to complicated anterior uveitis, leading to secondary glaucoma and loss of vision. Clinicians caring for people living with HIV should be alert to the complications of leishmaniasis that can occur before and during treatment. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Davies, O., Allen, F., Gruener, A. M., Simons, R., Graham, E. M., Larbalestier, N. Tags: Case reports Source Type: research

Anaphylactic-like reaction from trimethoprim-sulfamethoxazole in a patient with AIDS
We report a patient with AIDS who had an anaphylactic-like reaction from trimethoprim-sulfamethoxazole. Clinical suspicion of anaphylaxis should be considered in patients presenting with fever, hypotension, eosinophilia, rash, flushing or pulmonary infiltrates after initial exposure and re-exposure to the medication. This case highlights the need for healthcare professionals to be reminded of the association between this unusual antibiotic reaction resembling sepsis and HIV disease. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Persichino, J., Sutjita, M. Tags: Case reports Source Type: research

Routine HIV testing in acute medical admissions in a high prevalence area reduces morbidity and mortality of HIV: a full cycle audit
Late HIV diagnosis in the UK remains a major cause of morbidity and mortality. In line with British HIV Association recommendations, we implemented routine HIV Screening in Croydon University Hospital Acute Medical Unit in London after an audit in 2011 revealed very high levels of late diagnosis. Our re-audit assessed the impact of Acute Medical Unit screening and found that patients identified by screening, compared to those tested due to clinical suspicion of HIV, were significantly less likely to be diagnosed late, had fewer AIDS-defining illnesses and shorter hospital admissions. In addition, screening identified patie...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Hill-Tout, R., Cormack, I., Elgalib, A. Tags: Audit report Source Type: research

Which sexually active female students get themselves tested for Chlamydia trachomatis? A cohort study
Using data from the Prevention of Pelvic Infection (POPI) chlamydia screening trial, we compared the characteristics of female students who did or did not get tested for chlamydia outside the trial during 12 months’ follow-up. Of the 2529 women in the trial, we excluded 68 chlamydia positives in the intervention group who were referred for treatment at baseline. Of the remaining 2461 women, 1980 (80%) answered the question about testing during follow-up on their 12 months’ questionnaire and were included in the cohort. Of 1980 respondents, 529 (27%) reported having an independent chlamydia test, including 30 (4...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Kerry, S. R., Nightingale, C. M., Hay, P., Oakeshott, P. Tags: Original research articles Source Type: research

Impaired glucose metabolism in HIV-infected pregnant women: a retrospective analysis
Metabolic complications, including diabetes mellitus, have been increasingly recognised in HIV-infected individuals since the introduction of antiretroviral therapy, particularly protease inhibitors (PIs). Pregnancy is also a risk factor for impaired glucose metabolism, and previous studies have given conflicting results regarding the contribution of PIs to impaired glucose tolerance (IGT) and gestational diabetes mellitus (GDM) in pregnant HIV-infected women. We conducted a retrospective review of all HIV-infected women attending a combined infectious disease and antenatal clinic between 2007 and 2013 who underwent a 100 ...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Moore, R., Adler, H., Jackson, V., Lawless, M., Byrne, M., Eogan, M., Lambert, J. S. Tags: Original research articles Source Type: research

HIV co-receptor tropism prediction remains stable over time in treatment-naïve patients
In this study, baseline tropism prediction remained valid for a median of 52 months, suggesting current guidelines recommending repeat testing after 90 days may be excessively conservative in their assessment of tropism stability. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Philip, K. E., Macartney, M. J., Conibear, T. C., Smith, C. J., Marshall, N., Johnson, M. A., Haque, T., Webster, D. P. Tags: Original research articles Source Type: research

The risk of non-melanoma skin cancer in HIV-infected patients: new data and meta-analysis
The role of HIV/AIDS in non-melanoma skin cancer (NMSC) is not well defined. We sought to update the evidence of the association between HIV/AIDS and risk of NMSC by gender and antiretroviral therapy (ART). We searched MEDLINE and EMBASE on 29 February 2014. Standardised incidence ratios with corresponding 95% confidence intervals were extracted and combined using generic inverse variance methods assuming a random effects model. Six studies including 78,794 patients with HIV/AIDS fulfilled the inclusion criteria. Analysis of all studies showed that HIV/AIDS was associated with an increased risk of NMSC (standardised incide...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Zhao, H., Shu, G., Wang, S. Tags: Original research articles Source Type: research

Vaginal douching and association with sexually transmitted infections among female sex workers in a prefecture of Yunnan Province, China
Vaginal douching is a common practice and has been hypothesised to increase a woman's risk for human of contracting HIV and sexually transmitted infections (STIs). Our objective was to assess the prevalence of douching and its association with STIs, genital symptoms and HIV/STI knowledge among female sex workers (FSWs). We conducted a cross-sectional study of 837 FSWs with interviews and laboratory tests for HIV/STIs in a prefecture of Yunnan Province in southern China. Vaginal douching was reported by 84% of the women. We found a higher prevalence of vaginal douching practice among FSWs of Han ethnicity, and who were sing...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Luo, L., Xu, J.-J., Wang, G.-X., Ding, G.-W., Wang, N., Wang, H.-B. Tags: Original research articles Source Type: research

Characteristics and genotype profiles of antiretroviral-naïve patients entering a Southern US HIV outpatient clinic 2009-2012
The US city of New Orleans was ranked second in the nation for estimated HIV case rates in 2011. Opt-out testing was established at the Interim Louisiana Hospital in New Orleans in 2013. The majority of new diagnoses were referred to the HIV outpatient program. We conducted a retrospective chart review of newly referred antiretroviral-naïve patients establishing HIV care between January 2009 and June 2013 to characterise demographic and genotype profiles to assist in clinical management and needed services. Of the eligible 226 patients, 68% were men, and 88% were African American. Nearly half of the study patients ...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Seal, P. S., Frontini, M., Jhita, P. K., Deichmann, P. C., Clark, R. A. Tags: Original research articles Source Type: research

Prevalence and concordance of human papillomavirus infection at multiple anatomic sites among HIV-infected women from Chennai, India
Human papillomavirus (HPV) infection at the cervix, anus and oropharynx has been rarely concurrently estimated among HIV-infected women. Using multiplex polymerase chain reaction testing, we prospectively evaluated HPV genotype distribution across three anatomic sites among 50 eligible HIV-infected women from Chennai, India, who provided biological specimens and answered a sexual behaviour questionnaire. We also assessed clinical and behavioural factors related to HPV prevalence. Oncogenic HPV prevalence was comparable between the anus and cervix at 52.2% and 52.0% and lower at the oropharynx at 13.2%; 78% of women with a ...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Menezes, L. J., Poongulali, S., Tommasino, M., Lin, H.-Y., Kumarasamy, N., Fisher, K. J., Saravanan, S., Gheit, T., Ezhilarasi, C., Jeeva, A., Lu, B., Giuliano, A. R. Tags: Original research articles Source Type: research

HIV research trials versus standard clinics for antiretroviral-naïve patients: the outcomes differ but do the patients?
Exclusion criteria for HIV treatment-naïve drug trials can be stringent and selection bias exists, making it difficult to extrapolate results into the ‘real world’ clinical situation. We aim to compare the demographics, virological outcomes and psychosocial complexity in adult HIV-infected treatment-naïve patients from our cohort initiating combination antiretroviral therapy (cART) in research trials versus standard clinics. In our unit from 2006 to 2011, 1202 standard clinic and 69 research trial patients initiated cART; every eighth standard clinics patient was included to create a standard cl...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Williams, A., Wallis, E., Orkin, C. Tags: Original research articles Source Type: research

Acceptability and feasibility of HIV self-testing among men who have sex with men in Peru and Brazil
HIV self-testing has the potential to increase testing frequency and uptake. This pilot study assessed the feasibility and acceptability of HIV self-testing in a sample of sexually active men who have sex with men (MSM) in Peru and Brazil. Participants were trained to use a whole blood rapid HIV self-test and instructed to use the self-test monthly during this three-month study. Test acceptability was measured with self-reported use of the test at the one-month and three-month study visits, and test feasibility was assessed by direct observation of self-test administration at the final three-month visit. A total of 103 par...
Source: International Journal of STD and AIDS - May 15, 2016 Category: Global & Universal Authors: Volk, J. E., Lippman, S. A., Grinsztejn, B., Lama, J. R., Fernandes, N. M., Gonzales, P., Hessol, N. A., Buchbinder, S. Tags: Original research articles Source Type: research