International Journal of Rheumatic Diseases This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Implication of intestinal microbiota in the etiopathogenesis of fibromyalgia: A systematic review
AbstractFibromyalgia (FM) is a highly prevalent chronic disease. About 4.7% of the world's population suffers from generalized pain and hypersensitivity, in addition to a wide range of physical and psychological symptoms. The etiopathogenesis of this disease is multifactorial, which makes its diagnosis and treatment challenging. Recently, the increase in the number of studies on microbiota has provided new data that can help to understand the onset and development of FM. An updated systematic review of the causes of FM has been carried out in this work. Particularly in the last decade, research has focused on the gut –br...
Source: International Journal of Rheumatic Diseases - January 27, 2024 Category: Rheumatology Authors: Juan Francisco Palma ‐Ordóñez, Ana María Moreno‐Fernández, Jorge Antolín Ramírez‐Tejero, Elena Durán‐González, Antonio Martínez‐Lara, David Cotán Tags: REVIEW Source Type: research

The double shared epitope: Its impact on clinical features and ultrasound findings in rheumatoid arthritis
ConclusionsPatients with the double SE exhibited distinct characteristics, increased disease activity, and improved response to abatacept treatment. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 26, 2024 Category: Rheumatology Authors: Tohru Michitsuji, Shoichi Fukui, Ayako Nishino, Yushiro Endo, Kaori Furukawa, Toshimasa Shimizu, Masataka Umeda, Remi Sumiyoshi, Tomohiro Koga, Naoki Iwamoto, Tomoki Origuchi, Atsushi Kawakami, Shin ‐ya Kawashiri Tags: ORIGINAL ARTICLE Source Type: research

Melorheostosis: A rare disease of the bone
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 25, 2024 Category: Rheumatology Authors: Ali Karakas, Sadettin Uslu Tags: CLINICAL IMAGE Source Type: research

Molecules in the hippo pathway that regulate Th17 differentiation reveal the severity of ankylosing spondylitis
ConclusionOur findings suggest that the Hippo pathway plays a significant role in the regulation of Th17 differentiation and disease activity in patients with AS. The upregulation of TAZ and downregulation of key Hippo pathway proteins, such as MST1/2 and NDR1/2, may contribute to AS pathogenesis. These proteins may serve as biomarkers and may lead to the development of novel therapeutic strategies for AS. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 25, 2024 Category: Rheumatology Authors: Xiaohan Xu, Wanlin Liu, Yue Liu, Dongmei Wu, Bo Pang, Zhe Zhao, Yanan Zhao, Hongxiao Liu Tags: ORIGINAL ARTICLE Source Type: research

Validation of diagnosis algorithms for ankylosing spondylitis in claim ‐based database
ConclusionsWhile performing database studies, researchers should be aware of the low PPV of specific algorithms when defining AS. Algorithms with higher PPV were recommended to be adopted to avoid misclassification biases. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 25, 2024 Category: Rheumatology Authors: Shuo ‐Yan Gau, Hsiang‐En Tsai, Yu‐Hsun Wang, James Cheng‐Chung Wei Tags: ORIGINAL ARTICLE Source Type: research

Association between serum uric acid levels and lung function in the NHANES cohort (2007 –2012): A cross‐sectional analysis of a diverse American population
ConclusionSerum UA levels are inversely associated with FEV1 and FVC in the American population, with a notable impact on non-Hispanic Black females under 60. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 25, 2024 Category: Rheumatology Authors: Tianlun Kang, Yajing Xi, Siyi Lu, Tangliang Qian, Mengmeng Du, Xiaojun Shi, Xiujuan Hou Tags: ORIGINAL ARTICLE Source Type: research

Calcinosis in systemic sclerosis
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Catarina Borges Fernandes, Paulo Torres Ramalho Tags: CLINICAL IMAGE Source Type: research

Oligoarticular enthesitis ‐related arthritis and tofacitinib suitability: A case‐based literature review
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Vicen ç Torrente‐Segarra Tags: COMMENT Source Type: research

Psoriatic arthritis: Overcoming the obstacles of early diagnosis and optimal management
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Ranran Yao, An ‐Ping Huo, Yuan Jia, Yin Su Tags: EDITORIAL Source Type: research

Association between laughter, frailty, and depression in rheumatoid arthritis patients
ConclusionFrailty and depression were associated with laughter in RA patients with controlled disease activity. Interventions aimed at not only disease activity control but also frailty prevention may lead to a life filled with laughter. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Mochihito Suzuki, Toshihisa Kojima, Kenya Terabe, Yoshifumi Ohashi, Ryo Sato, Hironobu Kosugiyama, Junya Hasegawa, Yusuke Ohno, Kaoru Nagai, Chinami Ohnishi, Hideshi Sugiura, Hitomi Fujita, Mako Nagayoshi, Masayo Kojima, Shuji Asai, Shiro I Tags: ORIGINAL ARTICLE Source Type: research

STA ‐21 regulates Th‐17/Treg balance and synovial fibroblasts functions in rheumatoid arthritis
In this study, we tested whether a STAT3 inhibitor, STA-21, can alter Th-17/Treg balance and SF functions in RA. Peripheral blood mononuclear cells (PBMC) and SFs were isolated from 34 RA patients undergoing orthopedic surgery and 15 healthy controls to investigate in  vitro effects of STA-21. The main assays were MTT assay, PI staining, reverse transcription-PCR (RT-PCR), flow cytometric analysis, and ELISA. Results showed that STA-21 reduced the proportion of Th-17 cells and the expression of STAT3 target genes, RORγt, IL-21, and IL-23R involved in Th-17 cell s differentiation while it conversely increased the proporti...
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Talar Ahmad Merza Mohammad, Badraldin Kareem Hamad, Avin Mohammad Arif Maroof, Shokhan Osman Mahmud Tags: ORIGINAL ARTICLE Source Type: research

Comment on: Genome ‐wide DNA methylation sequencing reveals epigenetic features and potential biomarkers of Sjögren syndrome
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Ranjeet Singh Mahla Tags: COMMENT Source Type: research

Efficacy of adalimumab combined with Tripterygium wilfordii Hook F in the treatment of patient with rheumatoid arthritis: A multicenter, open ‐label, randomized‐controlled trial
ConclusionsThere were no significant differences in efficacy and safety between ADA combined with TwHF versus ADA combined with MTX in the treatment of RA. TwHF might be an alternative treatment for RA patients who are intolerant to MTX. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Feng Luo, Shuo ‐Yan Gau, Yu‐xia Wu, Hou‐li Liao, Fang Tang, Qin Zhong, Ying Huang, Lei Hou, Zheng‐qi Liu, Jin‐long Cai, Yue‐peng Cao, Dao‐min Lu, Yang An, Wei‐ya Lan, Can Liu, Chang‐ming Chen, Er‐tao Jia, Xue‐ming Ya Tags: ORIGINAL ARTICLE Source Type: research

Assessment of oral methotrexate intolerance in Japanese adult patients with rheumatoid arthritis
ConclusionsJapanese adult patients with RA showed a high prevalence of MTX intolerance even in low-dose oral MTX. The MISA questionnaire was practical for finding patients with MTX intolerance. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Masatoshi Kanda, Mayumi Sato, Ken Nagahata, Yasuyoshi Naishiro, Rieko Murakami, Saho Honda, Chisako Suzuki Tags: ORIGINAL ARTICLE Source Type: research

Anti ‐MDA5 antibody‐associated clinically amyopathic dermatomyositis diagnosed after the onset of pulmonary hypertension
AbstractIdiopathic inflammatory myopathies (IIM) are a group of highly heterogeneous systemic autoimmune diseases, of which clinically amyopathic dermatomyositis (CADM) is a distinct sub-type. Pulmonary hypertension (PH) is a life-threatening medical condition that can occur as a complication of connective tissue diseases. Herein, our report first suggests that PH can develop in CADM. A 48-year-old woman came to our hospital due to a 3  months history of facial edema and shortness of breath. Relevant examinations revealed Gottron's sign, normal creatinine kinase levels, elevated levels of mean pulmonary artery pressure, ...
Source: International Journal of Rheumatic Diseases - January 24, 2024 Category: Rheumatology Authors: Y. Yang, X. Huang, J. Lin Tags: CASE REPORT Source Type: research