Overlap of obsessive-compulsive personality disorder and autism spectrum disorder traits among OCD outpatients: an exploratory study.
Authors: Gadelkarim W, Shahper S, Reid J, Wikramanayake M, Kaur S, Kolli S, Osman S, Fineberg NA Abstract Background: Whereas the phenomenology of obsessive-compulsive personality disorder (OCPD) shows similarities to that of obsessive compulsive and related disorders (OCRDs) as well as with autism spectrum disorder (ASD), the relationship between these disorders is poorly understood. Aims: Within a clinical sample, we aimed to investigate the distribution of OCD, OCPD and ASD symptoms and traits and their interrelationship, as well as to evaluate insight and treatment refractoriness. Methods: Consecutive adult OCD...
Source: International Journal of Psychiatry in Clinical Practice - August 5, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Mullerian inhibiting substance, sex hormone binding globulin and sex hormone levels in stimulant-na ïve, first-diagnosed prepubertal boys with attention-deficit/hyperactivity disorder: comparison with matched healthy controls as well as before and after oros-methylpenidate treatment.
Mullerian inhibiting substance, sex hormone binding globulin and sex hormone levels in stimulant-naïve, first-diagnosed prepubertal boys with attention-deficit/hyperactivity disorder: comparison with matched healthy controls as well as before and after oros-methylpenidate treatment. Int J Psychiatry Clin Pract. 2019 Jul 24;:1-7 Authors: Gokcen C, Erbagci AB, Mutluer T, Orkmez M, Correll CU Abstract Objectives: Attention-Deficit/Hyperactivity Disorder (ADHD) is a complex neurodevelopmental disorder with strong male predominance. Since Müllerian Inhibiting Substance (MIS) produces sex-linked bi...
Source: International Journal of Psychiatry in Clinical Practice - July 26, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Unconjugated bilirubin and acute psychosis: a five years retrospective observational and controlled study in patients with schizophrenia, schizoaffective and bipolar disorders.
Authors: Gama Marques J, Pedro I, Ouakinin S Abstract Introduction: Unconjugated bilirubin (UCB) high levels have been correlated with schizophrenia spectrum disorders. Methods: We searched for correlation between UCB mean levels, duration of psychiatric admission, and diagnosis in 255 individuals, including 56 healthy controls and 199 acute patients (namely 44 with schizophrenia, 99 with schizoaffective disorder and 56 with bipolar disorder). Results: We found a statistically significant difference between UCB mean levels of patients with schizophrenia versus patients with schizoaffective (0.41 mg/dL vs. 0....
Source: International Journal of Psychiatry in Clinical Practice - July 24, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Editorial.
Authors: Kasper S PMID: 31284805 [PubMed - in process] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - July 11, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Where does it hurt? Location of pain, psychological distress, and alexithymia among outpatients seeking psychotherapy.
Conclusions: Back, head and neck pains are highly prevalent among psychiatric outpatients. Multiple pain sites may reflect higher levels of psychiatric distress and greater impairment in emotional processing among psychiatric outpatients. PMID: 31271073 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - July 6, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Comorbidity between ADHD and anxiety disorders across the lifespan.
Conclusions: The management of individuals with comorbid ADHD and anxiety disorders could be challenging for clinicians, and assessing the developmental course is crucial in order to shed light on individualised treatment. Keypoints The comorbidity between ADHD and anxiety disorders changes the clinical presentation, the prognosis and treatment of patients with ADHD across lifespan. ADHD and anxiety disorders shared common neurobiological dysfunctions but have also different neurobiological abnormalities suggesting that they are different diagnoses. These patients are less likely to benefit from cognitive behavioural treat...
Source: International Journal of Psychiatry in Clinical Practice - June 26, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Investigating duration of illness and duration of untreated illness in obsessive compulsive disorder reveals patients remain at length pharmacologically untreated.
Conclusions: The current literature clearly converge in delineate a duration of untreated illness of several years (around 7 years in the majority of them), which represented on average, a portion ranging between the 40 and 70% of the overall duration of untreated illness. PMID: 31144538 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - June 1, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Psychopharmacological treatment of patients with borderline personality disorder: comparing data from routine clinical care with recommended guidelines.
Conclusions: The present study shows that in routine clinical care settings psychotropic medications are frequently prescribed to patients with BPD, very often resulting in polypharmacy. A positive association between the number of medications and the effectiveness of the inpatient treatment program, as well as the absence of a relationship between number of medications and comorbidity contradicts the often suggested iatrogenic effect of polypharmacy. Key points Guidelines for pharmacotherapy of borderline personality disorders lack consensus Yet, clinicians frequently prescribe psychotropic medications to BPD patients Typ...
Source: International Journal of Psychiatry in Clinical Practice - May 31, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

A nomogram for predicting depression in patients with hepatocellular carcinoma: an observational cross-sectional study.
Conclusions: We proposed a nomogram for the individualised prediction of depression in hepatocellular carcinoma patients with satisfactory performance and clinical utility. Key points/highlights A visual, comprehensive and convenient nomogram was established for the prediction of depression in patients with hepatocellular carcinoma. The proposed nomogram showed satisfactory validity, discrimination and clinical utility, indicating good performance for predicting depression. The variables found to be sufficiently informative and predictive to warrant inclusion in the nomogram were the patient education level, pain intensity...
Source: International Journal of Psychiatry in Clinical Practice - May 30, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Editorial.
Authors: Kasper S PMID: 31131652 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - May 30, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Serum osmolarity and blood viscosity as a potential explanation for the pathophysiology of neuroleptic malignant syndrome.
Conclusions: Our findings indicate that serum osmolarity of NMS group was statistically significantly higher than the controls. In terms of blood viscosity, there was no statistically significant difference between groups. Higher serum osmolarity in NMS patients than controls may be a reflection of a relative hemoconcentration in NMS. KEY POINTS NMS is usually associated with dehydration resulting in fluid-electrolyte imbalance. We compared the NMS episodes with non-NMS hospitalizations (as control group) of the same patients. Serum osmolarity was statistically significantly higher in NMS group than the controls. There was...
Source: International Journal of Psychiatry in Clinical Practice - May 24, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Costs of inpatient care of depression in 2014 in Polish (Poznan) and German (Kiel) hospital.
CONCLUSIONS: The 3-fold difference in average costs of hospitalisation might result from differences in funding of mental health care which in Poland needs urgent amendment. Besides, mental health care was underfunded in Poznan. In general, treatment was comprehensive in both centres. Non-pharmacological treatment, however, was more comprehensive in Kiel. KEY POINTS The cost of inpatient care of depression was very high both in Kiel and Poznan. Inpatient care of depression is long-lasting, but a reduction in the length of hospital stay seems to be possible. Hospital stay is the main part of costs of inpatient care of depre...
Source: International Journal of Psychiatry in Clinical Practice - May 21, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

The association of functional polymorphism of matrix metalloproteinase-9 gene (rs3918242) with schizophrenia: a meta-analysis.
CONCLUSIONS: MMP-9 rs3918242 polymorphism may not be associated with schizophrenia. Given a crucial role of MMP-9 molecule on the pathogenesis of schizophrenia, this result should be verified by more studies with scientifically rigorous design and large population. PMID: 31094241 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - May 18, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Occupational status and hospitalisation for mental disorders: findings from Friuli Venezia Giulia region, Italy, 2008-2017.
CONCLUSIONS: Employment was protective for urgent and involuntary hospitalisations and severe diagnoses. Hospitalisation for affective disorders was more likely in managers, army, and for substances abuse in blue collars. More research is needed to assess the association between specific occupational groups and involuntary hospitalisation. Keypoints Employment was shown to be a protective factor for both urgent and involuntary hospitalisations and diagnosis of severe mental disorder. Managers, police and military forces were at higher risk of being hospitalised for affective disorders, while blue collars were at higher ris...
Source: International Journal of Psychiatry in Clinical Practice - May 18, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Evaluation of plasma agmatine level and its metabolic pathway in patients with bipolar disorder during manic episode and remission period.
In this study, plasma agmatine, arginine decarboxylase, and agmatinase levels were measured during manic episode and remission period in patients with bipolar disorder. METHODS: Thirty healthy volunteers and 30 patients who meet Bipolar Disorder Manic Episode diagnostic criteria were included in the study. Additionally, the changes in the patient group between manic episode and remission period were examined. We evaluated the relationship between levels of l-arginine and arginine decarboxylase in the agmatine synthesis pathway, and level of agmatinase that degrades agmatine. RESULTS: Levels of agmatine and l-argini...
Source: International Journal of Psychiatry in Clinical Practice - May 15, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Diagnosing solvent-induced chronic toxic encephalopathy: the effect of underperformance in neuropsychological testing.
CONCLUSIONS: Most of the neuropsychological tests evaluated showed significant effects of underperformance. Performance on letter-number sequencing was not affected. In case of underperformance, the results of the neuropsychological assessment should be disregarded when weighing the final multi-disciplinary diagnosis, with the exception of letter-number sequencing. Key points A total of 54.1% of patients with suspected CSE referred for neuropsychological assessment was identified as having underperformed on one or both PVTs. Underperformance has a significant effect on most neuropsychological tests with the exception of le...
Source: International Journal of Psychiatry in Clinical Practice - May 15, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

A study on attentional bias and response inhibition of facial expressions in manic patients: evidence from eye movement.
CONCLUSION: These results demonstrate that compared to healthy controls, manic patients show a deficiency in processing speed. The patients showed no attentional vigilance to happy or sad expressions but did showed avoidance of the sad expression and focused more on the happy expression in later emotion processing. There were no impairments of response inhibition detected in manic patients. Key points Abnormal processing of emotional information and having aberrant inner-experiences of emotion is a feature of bipolar disorders. Processing speed is slow in manic patients versus healthy controls. Manic patients focused lesse...
Source: International Journal of Psychiatry in Clinical Practice - May 1, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Factors associated with the use and longer duration of seclusion and restraint in psychiatric inpatient settings: a retrospective chart review.
CONCLUSIONS: A variety of factors are associated with the use and longer duration of SR. Given the potentially harmful effects of these practices, further studies with larger samples and a wider range of quantitative outcome measures are warranted. Key points An F00 diagnosis, a history of epilepsy and antipsychotics usage may increase the use of SR. Antidepressants may decrease the use of SR. An F00 and F32 diagnosis may extend the duration of SR. PMID: 31035799 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - May 1, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Differential impairment patterns of the corticospinal tract segments in alcohol dependence.
CONCLUSIONS: These findings suggest that CST impairments may vary with the fibre arrangement patterns of its segments in alcohol dependence. Keypoints We reconstructed the CST using tractography based on DTI data and divided the CST into different segments in order to explore more detailed micro-structural integrity changes in alcoholisms. Alcohol-dependent patients showed decreased RD and MD for the bilateral inferior segments of the CSTs. The left-superior segment exhibited decreased FA and increased RD while the right one exhibited increased AD and MD. These findings suggest that CST impairments may vary with the fiber ...
Source: International Journal of Psychiatry in Clinical Practice - April 18, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Prevalence, comorbidity, quality of life and use of services of obsessive-compulsive disorder and subthreshold obsessive-compulsive symptoms in the general adult population of Greece.
CONCLUSIONS: OCD is an under-treated public health problem that needs more attention in Greece and elsewhere. Provision of specialised mental health services should be a priority for publicly funded national health systems. Keypoints OCD is common in the general population of Greece with few sociodemographic associations apart from subjective financial difficulties. The comorbidity pattern of the full-blown syndrome versus the subthreshold obsessive-compulsive symptoms is similar and differs in magnitude in the expected way. Quality of life in OCD is greatly reduced especially when there is chronicity and/or comorbidity wi...
Source: International Journal of Psychiatry in Clinical Practice - April 18, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Repetitive transcranial magnetic stimulation (rTMS) for depression: outcomes in a United Kingdom (UK) clinical practice.
CONCLUSIONS: The results show that a UK-based clinical service achieves similar results to those published internationally and that clinical rTMS can have significant impact on symptoms of depression in many patients with TRD. Health services are under pressure to make financial savings, investment in rTMS could reduce the long-term treatment costs associated with TRD. PMID: 30931656 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - April 3, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

A case-control study of paternal and maternal age as risk factors in mood disorders.
Authors: Fountoulakis KN, Gonda X, Siamouli M, Panagiotidis P, Moutou K, Nimatoudis I, Kasper S Abstract OBJECTIVE: Advanced parental age might constitute a risk factor for various disorders. We tested whether this concerns also mood disorder patients. METHODS: The study included 314 subjects (42 bipolar-BD patients; 21 manics and 21 depressives, 68 unipolar-UD, and 204 normal controls-NC). Analysis of Covariance (ANCOVA) and the calculation of the Relative Risk (RR) and the Odds Ratio (OR) were used for the analysis. RESULTS: Paternal age differed between NC and UD patients (29.42 ± 6....
Source: International Journal of Psychiatry in Clinical Practice - March 19, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Editorial.
Authors: Kasper S PMID: 30843456 [PubMed - in process] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - March 9, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

What are the critical incidents that affect how people cope with being detained under Section 136 of the Mental Health Act (1983, 2007)?
Authors: Goodall T, Newton E, Larkin M Abstract PURPOSE: Section 136 (S136) of the Mental Health Act (1983, 2007) provides legislative powers for police officers to detain those suspected of being 'mentally disordered' for a mental health assessment. Despite its increasing use, there is currently little qualitative research exploring detainee's experiences. METHODOLOGY: Participants recruited from NHS places of safety participated in a semi-structured interview. The novel application of Critical Incident Technique (CIT) within this study enabled the specific identification of critical incidents which mental hea...
Source: International Journal of Psychiatry in Clinical Practice - March 9, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Hyperprolactinemia in psychotic patients treated in monotherapy with long-acting injectable antipsychotics.
The objectives of this study were to determine the prevalence of HPRL among schizophrenic patients treated with long-acting injectable (LAI) antipsychotic drugs at our hospital, and to estimate gender effects in PRL levels in these patients. METHODS: This cross-sectional, retrospective, study analyzed 165 psychotic patients treatment with LAI antipsychotics in monotherapy from February to May of 2017 at the Psychiatry Specialized Care Units of the Elche General Hospital (Spain). RESULTS: The prevalence of antipsychotic-derived HPRL in our hospital was 52.41%. Patients treated with LAI formulations of paliperidone a...
Source: International Journal of Psychiatry in Clinical Practice - March 9, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

'I am dead': Cotard syndrome and dementia.
CONCLUSION: In this narrative review we emphasise the fact that cases of Cotard syndrome involving patients with dementia are reported quite infrequently. Published studies are limited to very short series or isolated cases. Clinicians are obliged to treat the disorder. They should be alert to the potential high risk inherent in this condition. Keypoints Cotard syndrome is a rare condition characterised by nihilistic delusions that may range from negation of existence of parts of the body to delusion of being dead. The prevalence and incidence of this rare syndrome are not known. Since Cotard's syndrome is conceptualised a...
Source: International Journal of Psychiatry in Clinical Practice - March 9, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

High rates of depression anxiety and suicidal ideation among inpatients in general hospital in China.
CONCLUSION: Depression, anxiety, and suicidal ideation were determined to be common psychological problems in Chinese inpatients. Chinese medical personnel must pay attention to the mental health conditions of inpatients, particularly inpatients with lower income, educational levels, and poor marital status. Key Points This is one of the first studies focusing on the prevalence of depression and anxiety in Chinese hospitalized inpatients in non-psychiatric departments of a general hospital. The PHQ-9 and GAD-7 were determined to be potential screening tools to aid Chinese medical workers in recognizing depression and anxie...
Source: International Journal of Psychiatry in Clinical Practice - February 16, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Cardiovascular events in hospitalised patients with schizophrenia: a survival analysis.
CONCLUSION: The ASCVD items should be included in the medical assessment in any patient with severe mental illness. Key points The major composite outcome of cardiovascular events rate was equal to 9.0 per 100 patient-years. The secondary composite outcome of cardiovascular events rate was equal to 7.2 per 100 patient-years (0.072 events per patient). The association between survival curve of patients with high and low CVR according to FRS score tended to significance. Patients classified as high cardiovascular risk according to ASCVD presented a reduced cardiovascular survival. The ASCVD items should be included in the me...
Source: International Journal of Psychiatry in Clinical Practice - February 13, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Switching medication products during the treatment of psychiatric illness.
CONCLUSION: When product switches are considered, they should only proceed with the full knowledge of both patient and provider. PMID: 30732488 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - February 9, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Choosing among second-generation antidepressant treatments for depressed patients with cardiac diseases.
CONCLUSIONS: Data reported in the present review should help physicians about their decision-making processes that govern SGAs use in CVD patients. PMID: 30707042 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - February 3, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Long-term cardiovascular safety of psychostimulants in children with attention deficit hyperactivity disorder.
CONCLUSIONS: In general psychostimulants were safe. To further elucidate negative effects of psychostimulants, long-term controlled and randomized studies in naturalistic settings are of interest. PMID: 30663922 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - January 23, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

The alteration of retinal nerve fibre layer thickness with repetitive transcranial magnetic stimulation in patients with treatment resistant major depression.
CONCLUSIONS: RNFL thickness is increased in treatment resistant major depression and rTMS over the left DLPFC further increases RNFL thickness in treatment resistant major depressive patients. PMID: 30596524 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - January 2, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Orexin/hypocretin receptor, Orx1, gene variants are associated with major depressive disorder.
CONCLUSION: This study suggests that, Orx1 rs10914456 and rs2271933 can be associated with MDD development. Hence, Orx1 rs10914456 variants may affect depressive symptom severity. PMID: 30596528 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - January 2, 2019 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Problematic internet use and feelings of loneliness.
CONCLUSIONS: Evolution created neurophysiological mechanisms to recognize satisfying social relationships based on sensory information and bodily feedback present in face-to-face interactions. These are greatly absent in online communication. Hence, online communication likely engenders feelings of loneliness. Keypoints Problematic internet use (PIU) has been related to loneliness and social networking. Online communication was shown to increase loneliness. Lack of romantic relationships did not explain the association of PIU with loneliness. Poorer family environment did not explain the association of PIU with loneliness....
Source: International Journal of Psychiatry in Clinical Practice - December 21, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial.
CONCLUSIONS: Based on our findings, cyproheptadine does not have any considerable preventive effect on sleeping and appetite disorders induced by methylphenidate in ADHD children. PMID: 30261781 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - September 30, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Editorial.
Authors: Kasper S PMID: 30067153 [PubMed - in process] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - August 2, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

They have got the blues: patient's mood- and disease activity-related psychological burden of rheumatoid arthritis on caregivers.
CONCLUSIONS: The psychological impact of RA on caregivers appears to be associated with patients' mood, disease activity and upper extremity functionality. PMID: 30039721 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - July 26, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Impact of a culturally adapted behavioural family psychoeducational programme in patients with schizophrenia in Egypt.
Authors: Khalil AH, ELNahas G, Ramy H, Abdel Aziz K, Elkholy H, El-Ghamry R Abstract OBJECTIVE: To study the effect of a culturally adapted, structured family intervention on symptom severity, medication attitudes and knowledge, social functioning and quality of life in patients with schizophrenia. METHODS: Thirty subjects with schizophrenia were selected to receive 14 sessions of a culturally adapted behavioural family psychoeducational programme (BFPEP). Another 30 subjects received standard treatment as usual (STU) for 6 months. Pre- and post-intervention outcomes were assessed using the Positive and Negativ...
Source: International Journal of Psychiatry in Clinical Practice - July 19, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Personalised and precision psychiatry: what do the CINP bipolar guidelines suggest?
Authors: Fountoulakis KN, Moeller HJ, Kasper S PMID: 29764259 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - May 17, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Association between T-182C, G1287A polymorphism in NET gene and suicidality in major depressive disorder in Chinese patients.
CONCLUSIONS: Our results suggest that the investigated polymorphisms are not major susceptibility factors in the etiology of MDD with suicidality. However, the results must be verified in larger samples and different ethnicities. PMID: 29703117 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - May 1, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

The screen for cognitive impairment in psychiatry (SCIP) is associated with disease severity and cognitive complaints in major depression.
Authors: Tourjman SV, Juster RP, Purdon S, Stip E, Kouassi E, Potvin S Abstract OBJECTIVE: To assess the relationship between the Screen for Cognitive Impairment in Psychiatry (SCIP) score and illness severity, subjective cognition and functioning in a cohort of major depressive disorder (MDD) patients. METHODS: Patients (n = 40) diagnosed with MDD (DSM-IV-TR) completed the SCIP, a brief neuropsychological test, and a battery of self-administered questionnaires evaluating functioning (GAF, SDS, WHODAS 2.0, EDEC, PDQ-D5). Disease severity was evaluated with the Hamilton Depression Rating Scale (HDR...
Source: International Journal of Psychiatry in Clinical Practice - March 24, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Topiramate mitigates weight gain in antipsychotic-treated patients with schizophrenia: meta-analysis of randomised controlled trials.
CONCLUSIONS: Topiramate was significantly superior to control group in mitigating weight gain and psychopathology in antipsychotic-treated patients with schizophrenia. The effects of topiramate augmentation need further investigations in larger definitive studies using methodological rigor and thorough assessments. PMID: 29557263 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - March 24, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Editorial.
Authors: Kasper S PMID: 29473466 [PubMed - in process] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - February 25, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Quality of life among patients during subacute phase following stroke during hospitalisation period in Shanghai.
CONCLUSIONS: The level of patient satisfaction, duration of hospitalisation and the severity of stroke were found to be the three important factors associated with SS-QOL at hospital discharge, indicating doctors might assist patients adjust to the consequences of stroke and improve the QOL of subacute stroke. PMID: 29457918 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - February 20, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Mental health care providers talk about their experiences preventing suicide in people with substance use disorders in South Africa: implications for clinical practice.
CONCLUSIONS: The ways in which mental health care providers think about suicide and make sense of their experiences affects their perceived abilities to prevent suicide. Educating mental health care providers to transcend the limitations of risk factor approaches to suicide prevention and utilise evidence-based strategies for treating substance use disorders and associated problems, may be important to empower them and make them feel competent in suicide prevention. Empowering people with substance use disorders may help prevent suicide and may require collaboration between mental health care providers and allied professio...
Source: International Journal of Psychiatry in Clinical Practice - February 18, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Gambling and its clinical correlates in university students.
CONCLUSIONS: Some level of gambling symptomatology is common in young adults and is associated with alcohol and drug use, as well as impulsive and compulsive behaviors. Clinicians should be aware of the presentation of problematic gambling and screen for it in primary care and mental health settings. PMID: 29426260 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - February 12, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Autonomous motivation and quality of life as predictors of physical activity in patients with schizophrenia.
CONCLUSION: Our findings help to understand the importance of autonomous motivation and quality of life for PA in patients with schizophrenia. Knowledge about these predictors may provide guidance to improve PA behaviour in this population. PMID: 29421942 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - February 10, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Mindfulness in severe and persistent mental illness: a systematic review.
CONCLUSIONS: Findings suggest that mindfulness is feasible for individuals with SPMI, and displays potential benefits in outcomes aside from psychotic symptoms. The effects of mindfulness in psychotic symptoms needs further investigation in larger definitive studies using methodological rigor and thorough assessments of other psychiatric populations who are also representative of SPMI. PMID: 29411670 [PubMed - as supplied by publisher] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - February 9, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Challenging predictions between affective temperaments, depression and anxiety in a Kosovo student community sample.
Authors: Shahini M, Shala M, Xhylani P, Gashi S, Borinca I, Erfurth A Abstract OBJECTIVE: The relationship between temperament and mental health problems is seen very important as we hope to explain the trajectory of this interaction. The aim of this study was to test the validity of affective temperaments for predicting psychiatric morbidity, by explaining the relationships between temperament, anxiety and depression in a community sample. METHODS: This was a cross-sectional study. The present sample consisted of 960 participants (347 male, 622 female) with a mean age of M = 28.4 (SD =&thi...
Source: International Journal of Psychiatry in Clinical Practice - January 29, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research

Editorial.
Authors: Kasper S PMID: 29355083 [PubMed - in process] (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - January 24, 2018 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research