High utilisers of emergency departments: the profile and journey of patients with mental health issues
CONCLUSION: The study revealed a disintegrated service system for ED high utilisers with mental health issues, resulting in suboptimal clinical outcomes and substantial costs. To deliver value-based mental healthcare our lessons were; (1) stabilise the system's interaction with the patient by ensuring service responses are consistent with their enhanced management plan (2) all the system's parts channel the patient into various support services including psychological treatment with one therapist.KEY POINTSThe top 200 high utilisers presented to emergency 1928 times within 12 monthsThe re-presentation rate amongst the stud...
Source: International Journal of Psychiatry in Clinical Practice - May 4, 2021 Category: Psychiatry Authors: Melissa Casey Dinali Perera Joanne Enticott Hung Vo Stana Cubra Ashlee Gravell Moana Waerea George Habib Source Type: research

Association of negative symptoms with cognitive impairment in Chinese Han patients with chronic schizophrenia
Int J Psychiatry Clin Pract. 2021 Apr 20:1-7. doi: 10.1080/13651501.2021.1912357. Online ahead of print.ABSTRACTOBJECTIVE: Cognitive impairment is an essential feature of schizophrenia; however, the relationship between clinical psychiatric symptoms with cognitive impairment is still unclear. Therefore, we aimed to assess cognitive deficits and the relationship between clinical symptoms and cognitive function in patients with chronic schizophrenia, which provide a reference guide for psychiatrists.METHODS: We compared the cognitive function in 312 schizophrenia inpatients and 397 healthy controls by using the Repeatable Ba...
Source: International Journal of Psychiatry in Clinical Practice - April 21, 2021 Category: Psychiatry Authors: Rongrong Zhu Dongmei Wang Gaoxia Wei Jiesi Wang Huixia Zhou Hang Xu Wenjia Wang Shuochi Wei Dachun Chen Meihong Xiu Li Wang Xiang Yang Zhang Source Type: research

Do neurocognitive functions in cannabis induced psychosis groups differ from schizophrenia with cannabis use? A controlled cross-sectional study
CONCLUSIONS: CIP and SZC had different degrees of impairment compared to controls, but on direct comparisons CIP had better general intelligence and attention.KEY POINTSCannabis-induced psychosis (CIP) may have different neurocognitive impairment than Schizophrenia with cannabis use (SZC)CIP performed better in tests for general intelligence and visual attention than SZCSZC had significant impairment in executive function, attention, verbal memory, and psychomotor speed than controlsCompared to controls, CIP performed significantly worse in some domains of executive functionCIP and SZC had different degrees of cognitive im...
Source: International Journal of Psychiatry in Clinical Practice - April 15, 2021 Category: Psychiatry Authors: Raghav Shah Abhishek Ghosh Ajit Avasthi Ritu Nehra Chirag K Ahuja Niranjan Khandelwal Source Type: research

How significant is the assessment of the DSM-5 'anxious distress' specifier in patients with major depressive disorder without comorbid anxiety disorders in the continuation/maintenance phase?
CONCLUSION: The DSM-5 ANXD was also common among MDD patients without comorbid anxiety disorders in the continuation/maintenance phase; it was significantly associated with greater depression severity and might be related to temperament associated with bipolar disorder.Key pointsDSM-5 anxious distress is common among MDD patients without comorbid anxiety disorders in the continuation/maintenance phase and correlated with some of their socio-demographic and clinical characteristics. • The presence of DSM-5 anxious distress was significantly associated with greater severity of depression and might be related to temperam...
Source: International Journal of Psychiatry in Clinical Practice - April 12, 2021 Category: Psychiatry Authors: Tempei Otsubo Choryo Hokama Nana Sano Yoshinori Watanabe Toshiaki Kikuchi Katsutoshi Tanaka Source Type: research

Serum B12, homocysteine, and anti-parietal cell antibody levels in children with autism
CONCLUSIONS: Deficiencies in micronutrients, such as B12, may play a role in the pathogenesis and clinical symptoms of autism. However, it is believed that these parameters should be analysed in a wider population to clarify their effect on the aetiology of ASD.KEY POINTWe hypothesised that low levels of vitamin B12 and homocysteine levels reported in previous studies might be associated with APCA levels.The homocysteine and B12 levels were found to be significantly lower in children with ASD. There was no significant difference in serum APCA levels.No significant relationship was found between B12 levels and APCA.Given al...
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Semih Erden Bet ül Akbaş İleri Çağla Sadıç Çelikkol Kevser Nalbant İbrahim Kılınç Abdullah Yazar Source Type: research

Confirmatory evaluation of the bipolar depression rating scale (BDRS) in a large sample of female patients with bipolar depression
CONCLUSIONS: The BDRS demonstrated psychometric validity in assessing depressive and mixed symptoms in Iranian women with BD in a depressive or mixed/manic phase.KEY POINTSThe Bipolar Depression Rating Scale (BDRS) was validated in Iranian women with BD.The BDRS showed a three-factor structure, similar to the original validation.The BDRS had good reliability based on Omega and test-retest coefficients.The findings provided evidence for the convergent and discriminant validity of the BDRS.PMID:33825607 | DOI:10.1080/13651501.2021.1904997 (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Vahid Khosravani Michael Berk Seyed Mehdi Samimi Ardestani Farangis Sharifi Bastan Source Type: research

Serum B12, homocysteine, and anti-parietal cell antibody levels in children with autism
CONCLUSIONS: Deficiencies in micronutrients, such as B12, may play a role in the pathogenesis and clinical symptoms of autism. However, it is believed that these parameters should be analysed in a wider population to clarify their effect on the aetiology of ASD.KEY POINTWe hypothesised that low levels of vitamin B12 and homocysteine levels reported in previous studies might be associated with APCA levels.The homocysteine and B12 levels were found to be significantly lower in children with ASD. There was no significant difference in serum APCA levels.No significant relationship was found between B12 levels and APCA.Given al...
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Semih Erden Bet ül Akbaş İleri Çağla Sadıç Çelikkol Kevser Nalbant İbrahim Kılınç Abdullah Yazar Source Type: research

Confirmatory evaluation of the bipolar depression rating scale (BDRS) in a large sample of female patients with bipolar depression
CONCLUSIONS: The BDRS demonstrated psychometric validity in assessing depressive and mixed symptoms in Iranian women with BD in a depressive or mixed/manic phase.KEY POINTSThe Bipolar Depression Rating Scale (BDRS) was validated in Iranian women with BD.The BDRS showed a three-factor structure, similar to the original validation.The BDRS had good reliability based on Omega and test-retest coefficients.The findings provided evidence for the convergent and discriminant validity of the BDRS.PMID:33825607 | DOI:10.1080/13651501.2021.1904997 (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Vahid Khosravani Michael Berk Seyed Mehdi Samimi Ardestani Farangis Sharifi Bastan Source Type: research

Serum B12, homocysteine, and anti-parietal cell antibody levels in children with autism
CONCLUSIONS: Deficiencies in micronutrients, such as B12, may play a role in the pathogenesis and clinical symptoms of autism. However, it is believed that these parameters should be analysed in a wider population to clarify their effect on the aetiology of ASD.KEY POINTWe hypothesised that low levels of vitamin B12 and homocysteine levels reported in previous studies might be associated with APCA levels.The homocysteine and B12 levels were found to be significantly lower in children with ASD. There was no significant difference in serum APCA levels.No significant relationship was found between B12 levels and APCA.Given al...
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Semih Erden Bet ül Akbaş İleri Çağla Sadıç Çelikkol Kevser Nalbant İbrahim Kılınç Abdullah Yazar Source Type: research

Confirmatory evaluation of the bipolar depression rating scale (BDRS) in a large sample of female patients with bipolar depression
CONCLUSIONS: The BDRS demonstrated psychometric validity in assessing depressive and mixed symptoms in Iranian women with BD in a depressive or mixed/manic phase.KEY POINTSThe Bipolar Depression Rating Scale (BDRS) was validated in Iranian women with BD.The BDRS showed a three-factor structure, similar to the original validation.The BDRS had good reliability based on Omega and test-retest coefficients.The findings provided evidence for the convergent and discriminant validity of the BDRS.PMID:33825607 | DOI:10.1080/13651501.2021.1904997 (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Vahid Khosravani Michael Berk Seyed Mehdi Samimi Ardestani Farangis Sharifi Bastan Source Type: research

Serum B12, homocysteine, and anti-parietal cell antibody levels in children with autism
CONCLUSIONS: Deficiencies in micronutrients, such as B12, may play a role in the pathogenesis and clinical symptoms of autism. However, it is believed that these parameters should be analysed in a wider population to clarify their effect on the aetiology of ASD.KEY POINTWe hypothesised that low levels of vitamin B12 and homocysteine levels reported in previous studies might be associated with APCA levels.The homocysteine and B12 levels were found to be significantly lower in children with ASD. There was no significant difference in serum APCA levels.No significant relationship was found between B12 levels and APCA.Given al...
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Semih Erden Bet ül Akbaş İleri Çağla Sadıç Çelikkol Kevser Nalbant İbrahim Kılınç Abdullah Yazar Source Type: research

Confirmatory evaluation of the bipolar depression rating scale (BDRS) in a large sample of female patients with bipolar depression
CONCLUSIONS: The BDRS demonstrated psychometric validity in assessing depressive and mixed symptoms in Iranian women with BD in a depressive or mixed/manic phase.KEY POINTSThe Bipolar Depression Rating Scale (BDRS) was validated in Iranian women with BD.The BDRS showed a three-factor structure, similar to the original validation.The BDRS had good reliability based on Omega and test-retest coefficients.The findings provided evidence for the convergent and discriminant validity of the BDRS.PMID:33825607 | DOI:10.1080/13651501.2021.1904997 (Source: International Journal of Psychiatry in Clinical Practice)
Source: International Journal of Psychiatry in Clinical Practice - April 7, 2021 Category: Psychiatry Authors: Vahid Khosravani Michael Berk Seyed Mehdi Samimi Ardestani Farangis Sharifi Bastan Source Type: research

Psychological distress experienced by self-quarantined undergraduate university students in Lebanon during the COVID-19 outbreak
CONCLUSION: Despite being a necessary preventive measure during infectious disease outbreaks, quarantine can be associated with negative psychological effects, particularly in undergraduate students. Providing preventive and effective interventions is of utmost necessity.KEY POINTSDuring COVID-19, three-quarter of students had high risk for acute stress.Females had higher odds of high-risk acute stress compared to males.Having a chronic medical condition was associated with high risk acute stress.Long quarantine and lack of supplies were associated with high risk acute stress.Providing interventions to protect the mental h...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Ghida Kassir Samer El Hayek Hussein Zalzale Laura Orsolini Maya Bizri Source Type: research

Challenges in assessing change in autistic adults: scale limitations and discrepancies in reporting in clinical trials
Int J Psychiatry Clin Pract. 2021 Mar 28:1-5. doi: 10.1080/13651501.2021.1900871. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is a developmental disorder marked by deficits in social communication and social interaction, together with restricted and/or repetitive patterns of behaviours, activities or interests. As more adults are being diagnosed with ASD, and more diagnosed children are aging into adulthood, the need for effective treatments and support services for autistic adults is quickly growing. As such, clinical research targeting autistic adults has emerged in recent years. Currently, caregiver rat...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Emma Racine Bonnie P Taylor Casara J Ferretti Ellen Doernberg Rachel Noone Vera Nezgovorova Tarini Vats Eric Hollander Source Type: research

Psychological distress experienced by self-quarantined undergraduate university students in Lebanon during the COVID-19 outbreak
CONCLUSION: Despite being a necessary preventive measure during infectious disease outbreaks, quarantine can be associated with negative psychological effects, particularly in undergraduate students. Providing preventive and effective interventions is of utmost necessity.KEY POINTSDuring COVID-19, three-quarter of students had high risk for acute stress.Females had higher odds of high-risk acute stress compared to males.Having a chronic medical condition was associated with high risk acute stress.Long quarantine and lack of supplies were associated with high risk acute stress.Providing interventions to protect the mental h...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Ghida Kassir Samer El Hayek Hussein Zalzale Laura Orsolini Maya Bizri Source Type: research

Challenges in assessing change in autistic adults: scale limitations and discrepancies in reporting in clinical trials
Int J Psychiatry Clin Pract. 2021 Mar 28:1-5. doi: 10.1080/13651501.2021.1900871. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is a developmental disorder marked by deficits in social communication and social interaction, together with restricted and/or repetitive patterns of behaviours, activities or interests. As more adults are being diagnosed with ASD, and more diagnosed children are aging into adulthood, the need for effective treatments and support services for autistic adults is quickly growing. As such, clinical research targeting autistic adults has emerged in recent years. Currently, caregiver rat...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Emma Racine Bonnie P Taylor Casara J Ferretti Ellen Doernberg Rachel Noone Vera Nezgovorova Tarini Vats Eric Hollander Source Type: research

Psychological distress experienced by self-quarantined undergraduate university students in Lebanon during the COVID-19 outbreak
CONCLUSION: Despite being a necessary preventive measure during infectious disease outbreaks, quarantine can be associated with negative psychological effects, particularly in undergraduate students. Providing preventive and effective interventions is of utmost necessity.KEY POINTSDuring COVID-19, three-quarter of students had high risk for acute stress.Females had higher odds of high-risk acute stress compared to males.Having a chronic medical condition was associated with high risk acute stress.Long quarantine and lack of supplies were associated with high risk acute stress.Providing interventions to protect the mental h...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Ghida Kassir Samer El Hayek Hussein Zalzale Laura Orsolini Maya Bizri Source Type: research

Challenges in assessing change in autistic adults: scale limitations and discrepancies in reporting in clinical trials
Int J Psychiatry Clin Pract. 2021 Mar 28:1-5. doi: 10.1080/13651501.2021.1900871. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is a developmental disorder marked by deficits in social communication and social interaction, together with restricted and/or repetitive patterns of behaviours, activities or interests. As more adults are being diagnosed with ASD, and more diagnosed children are aging into adulthood, the need for effective treatments and support services for autistic adults is quickly growing. As such, clinical research targeting autistic adults has emerged in recent years. Currently, caregiver rat...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Emma Racine Bonnie P Taylor Casara J Ferretti Ellen Doernberg Rachel Noone Vera Nezgovorova Tarini Vats Eric Hollander Source Type: research

Psychological distress experienced by self-quarantined undergraduate university students in Lebanon during the COVID-19 outbreak
CONCLUSION: Despite being a necessary preventive measure during infectious disease outbreaks, quarantine can be associated with negative psychological effects, particularly in undergraduate students. Providing preventive and effective interventions is of utmost necessity.KEY POINTSDuring COVID-19, three-quarter of students had high risk for acute stress.Females had higher odds of high-risk acute stress compared to males.Having a chronic medical condition was associated with high risk acute stress.Long quarantine and lack of supplies were associated with high risk acute stress.Providing interventions to protect the mental h...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Ghida Kassir Samer El Hayek Hussein Zalzale Laura Orsolini Maya Bizri Source Type: research

Challenges in assessing change in autistic adults: scale limitations and discrepancies in reporting in clinical trials
Int J Psychiatry Clin Pract. 2021 Mar 28:1-5. doi: 10.1080/13651501.2021.1900871. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is a developmental disorder marked by deficits in social communication and social interaction, together with restricted and/or repetitive patterns of behaviours, activities or interests. As more adults are being diagnosed with ASD, and more diagnosed children are aging into adulthood, the need for effective treatments and support services for autistic adults is quickly growing. As such, clinical research targeting autistic adults has emerged in recent years. Currently, caregiver rat...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Emma Racine Bonnie P Taylor Casara J Ferretti Ellen Doernberg Rachel Noone Vera Nezgovorova Tarini Vats Eric Hollander Source Type: research

Psychological distress experienced by self-quarantined undergraduate university students in Lebanon during the COVID-19 outbreak
CONCLUSION: Despite being a necessary preventive measure during infectious disease outbreaks, quarantine can be associated with negative psychological effects, particularly in undergraduate students. Providing preventive and effective interventions is of utmost necessity.KEY POINTSDuring COVID-19, three-quarter of students had high risk for acute stress.Females had higher odds of high-risk acute stress compared to males.Having a chronic medical condition was associated with high risk acute stress.Long quarantine and lack of supplies were associated with high risk acute stress.Providing interventions to protect the mental h...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Ghida Kassir Samer El Hayek Hussein Zalzale Laura Orsolini Maya Bizri Source Type: research

Challenges in assessing change in autistic adults: scale limitations and discrepancies in reporting in clinical trials
Int J Psychiatry Clin Pract. 2021 Mar 28:1-5. doi: 10.1080/13651501.2021.1900871. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is a developmental disorder marked by deficits in social communication and social interaction, together with restricted and/or repetitive patterns of behaviours, activities or interests. As more adults are being diagnosed with ASD, and more diagnosed children are aging into adulthood, the need for effective treatments and support services for autistic adults is quickly growing. As such, clinical research targeting autistic adults has emerged in recent years. Currently, caregiver rat...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Emma Racine Bonnie P Taylor Casara J Ferretti Ellen Doernberg Rachel Noone Vera Nezgovorova Tarini Vats Eric Hollander Source Type: research

Psychological distress experienced by self-quarantined undergraduate university students in Lebanon during the COVID-19 outbreak
CONCLUSION: Despite being a necessary preventive measure during infectious disease outbreaks, quarantine can be associated with negative psychological effects, particularly in undergraduate students. Providing preventive and effective interventions is of utmost necessity.KEY POINTSDuring COVID-19, three-quarter of students had high risk for acute stress.Females had higher odds of high-risk acute stress compared to males.Having a chronic medical condition was associated with high risk acute stress.Long quarantine and lack of supplies were associated with high risk acute stress.Providing interventions to protect the mental h...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Ghida Kassir Samer El Hayek Hussein Zalzale Laura Orsolini Maya Bizri Source Type: research

Challenges in assessing change in autistic adults: scale limitations and discrepancies in reporting in clinical trials
Int J Psychiatry Clin Pract. 2021 Mar 28:1-5. doi: 10.1080/13651501.2021.1900871. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is a developmental disorder marked by deficits in social communication and social interaction, together with restricted and/or repetitive patterns of behaviours, activities or interests. As more adults are being diagnosed with ASD, and more diagnosed children are aging into adulthood, the need for effective treatments and support services for autistic adults is quickly growing. As such, clinical research targeting autistic adults has emerged in recent years. Currently, caregiver rat...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Emma Racine Bonnie P Taylor Casara J Ferretti Ellen Doernberg Rachel Noone Vera Nezgovorova Tarini Vats Eric Hollander Source Type: research

Psychological distress experienced by self-quarantined undergraduate university students in Lebanon during the COVID-19 outbreak
CONCLUSION: Despite being a necessary preventive measure during infectious disease outbreaks, quarantine can be associated with negative psychological effects, particularly in undergraduate students. Providing preventive and effective interventions is of utmost necessity.KEY POINTSDuring COVID-19, three-quarter of students had high risk for acute stress.Females had higher odds of high-risk acute stress compared to males.Having a chronic medical condition was associated with high risk acute stress.Long quarantine and lack of supplies were associated with high risk acute stress.Providing interventions to protect the mental h...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Ghida Kassir Samer El Hayek Hussein Zalzale Laura Orsolini Maya Bizri Source Type: research

Challenges in assessing change in autistic adults: scale limitations and discrepancies in reporting in clinical trials
Int J Psychiatry Clin Pract. 2021 Mar 28:1-5. doi: 10.1080/13651501.2021.1900871. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is a developmental disorder marked by deficits in social communication and social interaction, together with restricted and/or repetitive patterns of behaviours, activities or interests. As more adults are being diagnosed with ASD, and more diagnosed children are aging into adulthood, the need for effective treatments and support services for autistic adults is quickly growing. As such, clinical research targeting autistic adults has emerged in recent years. Currently, caregiver rat...
Source: International Journal of Psychiatry in Clinical Practice - March 29, 2021 Category: Psychiatry Authors: Emma Racine Bonnie P Taylor Casara J Ferretti Ellen Doernberg Rachel Noone Vera Nezgovorova Tarini Vats Eric Hollander Source Type: research

Bright light therapy accelerates the antidepressant effect of repetitive transcranial magnetic stimulation in treatment resistant depression: a pilot study
Int J Psychiatry Clin Pract. 2021 Mar 18:1-3. doi: 10.1080/13651501.2021.1894579. Online ahead of print.ABSTRACTObjectives: We performed a randomized single-blinded study to assess the superiority of the combination strategy of repetitive Transcranial Magnetic Stimulation (rTMS) and Bright Light Therapy (BLT) over rTMS treatment alone in reducing depressive symptoms in treatment-resistant depression (TRD).Methods: We enrolled 80 inpatients with a diagnosis of TRD. All patients were randomly assigned into two groups: group A was treated with rTMS, compared to group B treated with a combination of rTMS and BLT. Depressive sy...
Source: International Journal of Psychiatry in Clinical Practice - March 18, 2021 Category: Psychiatry Authors: Barbara Barbini Francesco Attanasio Elena Manfredi Maria Cristina Cavallini Raffaella Zanardi Cristina Colombo Source Type: research