Revisiting informed consent in forensic genomics in light of current technologies and the times
AbstractInformed consent is based on basic ethical principles that should be considered when conducting biomedical and behavioral research involving human subjects. These principles —respect, beneficence, and justice—form the foundations of informed consent which in itself is grounded on three fundamental elements: information, comprehension, and voluntary participation. While informed consent has focused on human subjects and research, the practice has been adopted willing ly in the forensic science arena primarily to acquire reference samples from family members to assist in identifying missing persons. With advances...
Source: International Journal of Legal Medicine - January 16, 2023 Category: Medical Law Source Type: research

Solving the two-decades-old murder case through joint application of ZooMS and ancient DNA approaches
AbstractBones are one of the most common biological types of evidence in forensic cases. Discriminating human bones from irrelevant species is important for the identification of victims; however, the highly degraded bones could be undiagnostic morphologically and difficult to analyze with standard DNA profiling approaches. The same challenge also exists in archaeological studies. Here, we present an initial study of an analytical strategy that involves zooarchaeology by mass spectrometry (ZooMS) and ancient DNA methods. Through the combined strategy, we managed to identify the only biological evidence of a two-decades-old...
Source: International Journal of Legal Medicine - January 10, 2023 Category: Medical Law Source Type: research

Adventure Legal Medicine: a free online serious game for supplementary use in undergraduate medical education
AbstractSerious games (computer-based learning games) are increasingly used in medical education at various levels, as user access is independent of location and time and promotes non-linear learning. In legal medicine, interactive digital media are still scarce. The freely accessible online serious game “Adventure Legal Medicine” was developed as part of the “Hamburg Open Online University”. The goal was to teach the basics of forensic casework in a point-and-click adventure setting consisting of five cases. During development, 40 medical students were asked to evaluate the game anonymously . The System Usability ...
Source: International Journal of Legal Medicine - January 10, 2023 Category: Medical Law Source Type: research

Blunt force trauma and blast injuries to head and chest caused by a potent pyrotechnic device: a case report
We present a case of devastating blunt force and blast injuries to the head and chest of a young man. After ignition of a display shell (syn. a real shell or mortar shell) without the use of a launching pipe, the device hit the man ’s face, nearly simultaneously followed by the explosion of the burst charge. The autopsy revealed injuries to the face and forehead as well as extensive tissue structure damage and a massive contusion with a bloody edema of the lungs. Autopsy results are supplemented with CT imaging and 3D recons truction of the fractured mid face, as well as histological and toxicological examinations. This ...
Source: International Journal of Legal Medicine - January 7, 2023 Category: Medical Law Source Type: research

Evaluation of face masks as a valuable forensic DNA evidence in the post-COVID era
AbstractAfter the onset of COVID-19 pandemic, a sharp surge in the usage of the face-masks throughout the globe has been observed. Pre-experiment survey of 252 individuals indicated a higher use of cotton-make masks (41%), followed by N-95 make (31%), and surgical disposable masks (26%). It was also further revealed that a higher fraction of individuals wear a face-mask more than 3 times (37%) before its disposal. In order to assess the potential usability of different mask types as forensic DNA evidence, a study was conducted on 50 healthy individuals. DNA content of different fractions such as the portion of mask coverin...
Source: International Journal of Legal Medicine - January 7, 2023 Category: Medical Law Source Type: research