Metrological traceability in flow cytometry? Evaluation of a new volumetric method for lymphocyte subsets
CONCLUSION: A high degree of correlation was found for results from both methodologies and observed bias was within the limits of clinical acceptability for all populations. This shows that the metrologically traceable lymphocyte subset absolute counts produced by the Sysmex XF-1600 are robust within clinically required limits.PMID:38114449 | DOI:10.1111/ijlh.14219 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 19, 2023 Category: Hematology Authors: Rosalie Y Ward Matthew Stevens Sheriaz Bashir Source Type: research

Autoimmune-acquired coagulation factor V deficiency with hyperfibrinolytic disseminated intravascular coagulation
Int J Lab Hematol. 2023 Dec 19. doi: 10.1111/ijlh.14218. Online ahead of print.NO ABSTRACTPMID:38112128 | DOI:10.1111/ijlh.14218 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 19, 2023 Category: Hematology Authors: Yuto Kaneda Kenji Fukuno Hiroki Minami Yuri Nonaka Akiko Horinoue Yasunori Kuroki Tsukasa Osaki Masayoshi Souri Hidesaku Asakura Akitada Ichinose Source Type: research

Metrological traceability in flow cytometry? Evaluation of a new volumetric method for lymphocyte subsets
CONCLUSION: A high degree of correlation was found for results from both methodologies and observed bias was within the limits of clinical acceptability for all populations. This shows that the metrologically traceable lymphocyte subset absolute counts produced by the Sysmex XF-1600 are robust within clinically required limits.PMID:38114449 | DOI:10.1111/ijlh.14219 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 19, 2023 Category: Hematology Authors: Rosalie Y Ward Matthew Stevens Sheriaz Bashir Source Type: research

Autoimmune-acquired coagulation factor V deficiency with hyperfibrinolytic disseminated intravascular coagulation
Int J Lab Hematol. 2023 Dec 19. doi: 10.1111/ijlh.14218. Online ahead of print.NO ABSTRACTPMID:38112128 | DOI:10.1111/ijlh.14218 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 19, 2023 Category: Hematology Authors: Yuto Kaneda Kenji Fukuno Hiroki Minami Yuri Nonaka Akiko Horinoue Yasunori Kuroki Tsukasa Osaki Masayoshi Souri Hidesaku Asakura Akitada Ichinose Source Type: research

Metrological traceability in flow cytometry? Evaluation of a new volumetric method for lymphocyte subsets
CONCLUSION: A high degree of correlation was found for results from both methodologies and observed bias was within the limits of clinical acceptability for all populations. This shows that the metrologically traceable lymphocyte subset absolute counts produced by the Sysmex XF-1600 are robust within clinically required limits.PMID:38114449 | DOI:10.1111/ijlh.14219 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 19, 2023 Category: Hematology Authors: Rosalie Y Ward Matthew Stevens Sheriaz Bashir Source Type: research

Use of the oxygen gradient ektacytometry in the dose titration of hydroxyurea therapy in children with sickle cell disease
Int J Lab Hematol. 2023 Dec 17. doi: 10.1111/ijlh.14208. Online ahead of print.NO ABSTRACTPMID:38105480 | DOI:10.1111/ijlh.14208 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 18, 2023 Category: Hematology Authors: Maite E Houwing Jennifer Bos Richard van Wijk Eduard J van Beers Marjon H Cnossen Minke A E Rab SCORE consortium Source Type: research

Platelet-to-lymphocyte ratio and absolute monocyte count have prognostic potential in primary myelodysplastic neoplasms
CONCLUSION: Elevated PLR and increased AMC had independent prognostic value for adverse outcomes in patients with MDS. PLR, MLR, and AMC enhanced the IPSS-R risk categorization for OS prediction in MDS.PMID:38105483 | DOI:10.1111/ijlh.14215 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 18, 2023 Category: Hematology Authors: Huiting Qu Jingxue Chu Lu Wang Jie Zhang Jingyin Han Zhen Li Haifeng Hou Yong Wang Yigang Liu Huanling Wu Source Type: research

Use of the oxygen gradient ektacytometry in the dose titration of hydroxyurea therapy in children with sickle cell disease
Int J Lab Hematol. 2023 Dec 17. doi: 10.1111/ijlh.14208. Online ahead of print.NO ABSTRACTPMID:38105480 | DOI:10.1111/ijlh.14208 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 18, 2023 Category: Hematology Authors: Maite E Houwing Jennifer Bos Richard van Wijk Eduard J van Beers Marjon H Cnossen Minke A E Rab SCORE consortium Source Type: research

Platelet-to-lymphocyte ratio and absolute monocyte count have prognostic potential in primary myelodysplastic neoplasms
CONCLUSION: Elevated PLR and increased AMC had independent prognostic value for adverse outcomes in patients with MDS. PLR, MLR, and AMC enhanced the IPSS-R risk categorization for OS prediction in MDS.PMID:38105483 | DOI:10.1111/ijlh.14215 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 18, 2023 Category: Hematology Authors: Huiting Qu Jingxue Chu Lu Wang Jie Zhang Jingyin Han Zhen Li Haifeng Hou Yong Wang Yigang Liu Huanling Wu Source Type: research

MicroRNA-based therapies: Revolutionizing the treatment of acute myeloid leukemia
Int J Lab Hematol. 2023 Dec 17. doi: 10.1111/ijlh.14211. Online ahead of print.ABSTRACTMicroRNAs (miRNAs) are small noncoding epigenetic regulators that exert critical significance by influencing target mRNAs and governing gene expression patterns and cellular signaling pathways. miRNAs play a pivotal role in a wide array of biological processes, including cell differentiation, proliferation, and survival. Numerous miRNAs contribute to tumorigenesis and cancer progression by promoting tumor growth, angiogenesis, invasion, and immune evasion, while others exert tumor suppressive effects. From a clinical perspective, it has ...
Source: International Journal of Laboratory Hematology - December 17, 2023 Category: Hematology Authors: Radhakrishnan Chandraprabha Vineetha John Anitha Geetha Raj Padmakumar Devipriya Mohanan Sreelatha Mahitha Sreedharan Hariharan Source Type: research

Detection of dysplasia in peripheral blood: Proposal of an algorithm to detect myelodysplastic syndromes and chronic myelomonocytic leukemias on a high-speed technical platform using the Sysmex XN ™ analyser
CONCLUSION: We propose a flowchart using embedded artificial intelligence to help the cytologist in an optimized smear review and thus improve guidance to the clinician and the patients in the diagnosis process. This strategy permits a more comprehensive approach to MDS and CMML detection fitting with the new definition of CMML according to the recommendations of the World Health Organization (WHO) published in 2022.PMID:38083991 | DOI:10.1111/ijlh.14217 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 12, 2023 Category: Hematology Authors: Lakhdar Bouriche L éa Fuster Hugo Laurent Christophe Soler Sofiane Benhabib Source Type: research

Detection of dysplasia in peripheral blood: Proposal of an algorithm to detect myelodysplastic syndromes and chronic myelomonocytic leukemias on a high-speed technical platform using the Sysmex XN ™ analyser
CONCLUSION: We propose a flowchart using embedded artificial intelligence to help the cytologist in an optimized smear review and thus improve guidance to the clinician and the patients in the diagnosis process. This strategy permits a more comprehensive approach to MDS and CMML detection fitting with the new definition of CMML according to the recommendations of the World Health Organization (WHO) published in 2022.PMID:38083991 | DOI:10.1111/ijlh.14217 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 12, 2023 Category: Hematology Authors: Lakhdar Bouriche L éa Fuster Hugo Laurent Christophe Soler Sofiane Benhabib Source Type: research

Detection of dysplasia in peripheral blood: Proposal of an algorithm to detect myelodysplastic syndromes and chronic myelomonocytic leukemias on a high-speed technical platform using the Sysmex XN ™ analyser
CONCLUSION: We propose a flowchart using embedded artificial intelligence to help the cytologist in an optimized smear review and thus improve guidance to the clinician and the patients in the diagnosis process. This strategy permits a more comprehensive approach to MDS and CMML detection fitting with the new definition of CMML according to the recommendations of the World Health Organization (WHO) published in 2022.PMID:38083991 | DOI:10.1111/ijlh.14217 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 12, 2023 Category: Hematology Authors: Lakhdar Bouriche L éa Fuster Hugo Laurent Christophe Soler Sofiane Benhabib Source Type: research

Detection of dysplasia in peripheral blood: Proposal of an algorithm to detect myelodysplastic syndromes and chronic myelomonocytic leukemias on a high-speed technical platform using the Sysmex XN ™ analyser
CONCLUSION: We propose a flowchart using embedded artificial intelligence to help the cytologist in an optimized smear review and thus improve guidance to the clinician and the patients in the diagnosis process. This strategy permits a more comprehensive approach to MDS and CMML detection fitting with the new definition of CMML according to the recommendations of the World Health Organization (WHO) published in 2022.PMID:38083991 | DOI:10.1111/ijlh.14217 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 12, 2023 Category: Hematology Authors: Lakhdar Bouriche L éa Fuster Hugo Laurent Christophe Soler Sofiane Benhabib Source Type: research

Detection of dysplasia in peripheral blood: Proposal of an algorithm to detect myelodysplastic syndromes and chronic myelomonocytic leukemias on a high-speed technical platform using the Sysmex XN ™ analyser
CONCLUSION: We propose a flowchart using embedded artificial intelligence to help the cytologist in an optimized smear review and thus improve guidance to the clinician and the patients in the diagnosis process. This strategy permits a more comprehensive approach to MDS and CMML detection fitting with the new definition of CMML according to the recommendations of the World Health Organization (WHO) published in 2022.PMID:38083991 | DOI:10.1111/ijlh.14217 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 12, 2023 Category: Hematology Authors: Lakhdar Bouriche L éa Fuster Hugo Laurent Christophe Soler Sofiane Benhabib Source Type: research