Aberration correction in abdominal histotripsy
Int J Hyperthermia. 2023;40(1):2266594. doi: 10.1080/02656736.2023.2266594. Epub 2023 Oct 9.ABSTRACTIn transabdominal histotripsy, ultrasound pulses are focused on the body to noninvasively destroy soft tissues via cavitation. However, the ability to focus is limited by phase aberration, or decorrelation of the ultrasound pulses due to spatial variation in the speed of sound throughout heterogeneous tissue. Phase aberration shifts, broadens, and weakens the focus, thereby reducing the safety and efficacy of histotripsy therapy. This paper reviews and discusses aberration effects in histotripsy and in related therapeutic ul...
Source: International Journal of Hyperthermia - October 9, 2023 Category: Internal Medicine Authors: Ellen Yeats Timothy L Hall Source Type: research

Broadband microwave spiral applicator (105-125  MHz) for < em > in  vitro < /em > examinations of hyperthermia-induced tumor cell death forms - first analyses with human breast cancer cells
CONCLUSIONS: Well-characterized in vitro heating systems are mandatory for a better understanding of the biological effects of hyperthermia in tumor therapies and to finally determine optimized clinical treatment schemes.PMID:37813393 | DOI:10.1080/02656736.2023.2265590 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - October 9, 2023 Category: Internal Medicine Authors: Jannik Walter Michael Hader Azzaya Sengedorj Rainer Fietkau Benjamin Frey Udo S Gaipl Source Type: research

Aberration correction in abdominal histotripsy
Int J Hyperthermia. 2023;40(1):2266594. doi: 10.1080/02656736.2023.2266594. Epub 2023 Oct 9.ABSTRACTIn transabdominal histotripsy, ultrasound pulses are focused on the body to noninvasively destroy soft tissues via cavitation. However, the ability to focus is limited by phase aberration, or decorrelation of the ultrasound pulses due to spatial variation in the speed of sound throughout heterogeneous tissue. Phase aberration shifts, broadens, and weakens the focus, thereby reducing the safety and efficacy of histotripsy therapy. This paper reviews and discusses aberration effects in histotripsy and in related therapeutic ul...
Source: International Journal of Hyperthermia - October 9, 2023 Category: Internal Medicine Authors: Ellen Yeats Timothy L Hall Source Type: research

Broadband microwave spiral applicator (105-125  MHz) for < em > in  vitro < /em > examinations of hyperthermia-induced tumor cell death forms - first analyses with human breast cancer cells
CONCLUSIONS: Well-characterized in vitro heating systems are mandatory for a better understanding of the biological effects of hyperthermia in tumor therapies and to finally determine optimized clinical treatment schemes.PMID:37813393 | DOI:10.1080/02656736.2023.2265590 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - October 9, 2023 Category: Internal Medicine Authors: Jannik Walter Michael Hader Azzaya Sengedorj Rainer Fietkau Benjamin Frey Udo S Gaipl Source Type: research

Aberration correction in abdominal histotripsy
Int J Hyperthermia. 2023;40(1):2266594. doi: 10.1080/02656736.2023.2266594. Epub 2023 Oct 9.ABSTRACTIn transabdominal histotripsy, ultrasound pulses are focused on the body to noninvasively destroy soft tissues via cavitation. However, the ability to focus is limited by phase aberration, or decorrelation of the ultrasound pulses due to spatial variation in the speed of sound throughout heterogeneous tissue. Phase aberration shifts, broadens, and weakens the focus, thereby reducing the safety and efficacy of histotripsy therapy. This paper reviews and discusses aberration effects in histotripsy and in related therapeutic ul...
Source: International Journal of Hyperthermia - October 9, 2023 Category: Internal Medicine Authors: Ellen Yeats Timothy L Hall Source Type: research

Broadband microwave spiral applicator (105-125  MHz) for < em > in  vitro < /em > examinations of hyperthermia-induced tumor cell death forms - first analyses with human breast cancer cells
CONCLUSIONS: Well-characterized in vitro heating systems are mandatory for a better understanding of the biological effects of hyperthermia in tumor therapies and to finally determine optimized clinical treatment schemes.PMID:37813393 | DOI:10.1080/02656736.2023.2265590 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - October 9, 2023 Category: Internal Medicine Authors: Jannik Walter Michael Hader Azzaya Sengedorj Rainer Fietkau Benjamin Frey Udo S Gaipl Source Type: research

Aberration correction in abdominal histotripsy
Int J Hyperthermia. 2023;40(1):2266594. doi: 10.1080/02656736.2023.2266594. Epub 2023 Oct 9.ABSTRACTIn transabdominal histotripsy, ultrasound pulses are focused on the body to noninvasively destroy soft tissues via cavitation. However, the ability to focus is limited by phase aberration, or decorrelation of the ultrasound pulses due to spatial variation in the speed of sound throughout heterogeneous tissue. Phase aberration shifts, broadens, and weakens the focus, thereby reducing the safety and efficacy of histotripsy therapy. This paper reviews and discusses aberration effects in histotripsy and in related therapeutic ul...
Source: International Journal of Hyperthermia - October 9, 2023 Category: Internal Medicine Authors: Ellen Yeats Timothy L Hall Source Type: research

The use of histotripsy as intratumoral immunotherapy beyond tissue ablation-the rationale for exploring the immune effects of histotripsy
Int J Hyperthermia. 2023;40(1):2263672. doi: 10.1080/02656736.2023.2263672. Epub 2023 Oct 8.ABSTRACTMechanical high-intensity focused ultrasound (M-HIFU), which includes histotripsy, is a non-ionizing, non-thermal ablation technology that can be delivered by noninvasive methods. Because acoustic cavitation is the primary mechanism of tissue disruption, histotripsy is distinct from the conventional HIFU techniques resulting in hyperthermia and thermal injury. Phase I human trials have shown the initial safety and efficacy of histotripsy in treating patients with malignant liver tumors. In addition to tissue ablation, a prom...
Source: International Journal of Hyperthermia - October 8, 2023 Category: Internal Medicine Authors: Takuya Osada Xiaoning Jiang Yuhang Zhao Mengyue Chen Benjamin C Kreager Huaiyu Wu Howuk Kim Jun Ren Joshua Snyder Pei Zhong Michael A Morse H Kim Lyerly Source Type: research

Percutaneous ablation of colorectal liver metastases: a comparison between the outcomes of grayscale US guidance and Sonazoid CEUS Kupffer phase guidance using propensity score matching
CONCLUSION: For tumors with poor vision on grayscale US, Sonazoid CEUS guidance is recommended for better local tumor control.PMID:37788806 | DOI:10.1080/02656736.2023.2260573 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - October 3, 2023 Category: Internal Medicine Authors: Si Qin Jingwen Zhou Rui Cui Yao Chen Yimin Wang Guangjian Liu Source Type: research

Prediction of prognosis and immune landscape in cervical cancer based on heat shock protein-related genes
Conclusion: In summary, we built a good model to help predict the prognosis of CC patients and provide a reference for personalized treatment and medication for different patients.PMID:37750398 | DOI:10.1080/02656736.2023.2259140 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - September 26, 2023 Category: Internal Medicine Authors: Min Wang Zhizun Li Source Type: research

Ultrasound-guided percutaneous microwave ablation for adenomyosis with abnormal uterine bleeding: clinical outcome and associated factors
CONCLUSION: Baseline CA125 and ablation rate of the EMJ and SA of the ablated part of the EMJ are associated with the outcome of AUB-A patients after US-guided PMWA treatment.PMID:37751897 | DOI:10.1080/02656736.2023.2249274 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - September 26, 2023 Category: Internal Medicine Authors: Hui-Li Zhang Jing-E Zhu Er-Ya Deng Jia-Xin Li Li-Ping Sun Cheng-Zhong Peng Hui-Xiong Xu Song-Yuan Yu Source Type: research