Hyperthermia inhibits growth of nasopharyngeal carcinoma through degradation of c-Myc
CONCLUSION: Our study reveals that hyperthermia can readily destabilize c-Myc levels in NPC cells and inhibit tumor growth. This proposes new strategies for implementing hyperthermia to target c-Myc-driven cancers to improve therapeutic efficacy.PMID:35184661 | DOI:10.1080/02656736.2022.2038282 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 21, 2022 Category: Internal Medicine Authors: Xiaole Li Shichao Duan Yingjuan Zheng Yongqiang Yang Lei Wang Xinqiang Li Qing Zhang Rick F Thorne Wencai Li Daoke Yang Source Type: research

Comparison of efficacy, safety, and patient satisfaction between thermal ablation, conventional/open thyroidectomy, and endoscopic thyroidectomy for symptomatic benign thyroid nodules
CONCLUSIONS: Compared to ConT and ET, TA has comparable efficacy, safety, and patient satisfaction and exhibits greater protection of thyroid function for the treatment of symptomatic BTNs.PMID:35188057 | DOI:10.1080/02656736.2022.2040608 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 21, 2022 Category: Internal Medicine Authors: Xiao-Wan Bo Feng Lu Song-Yuan Yu Wen-Wen Yue Xiao-Long Li Man Hu Li-Li Wu Zhu-Ying Lv Li-Ping Sun Hui-Xiong Xu Source Type: research

Survival benefit of thermal ablation combined with chemotherapy for the treatment of stage IV nonsmall cell lung cancer: a propensity-matched analysis
CONCLUSION: TA plus chemotherapy is a potential treatment option for Stage-IV NSCLC, especially for patients aged 70 or older with tumor size ≤3 cm.PMID:35164638 | DOI:10.1080/02656736.2022.2038281 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 15, 2022 Category: Internal Medicine Authors: Hao Yang Mengqi Li Tonghua Mei Source Type: research

Ultrasound guided microwave ablation compared to uterine artery embolization treatment for uterine fibroids - a randomized controlled trial
CONCLUSIONS: Although superiority of MWA could not be established, it is a promising technique for treating uterine fibroids. It was well tolerated and associated with lower use of health care resources. Trial registration: NCT02942537, www.clincialtrials.gov.PMID:35134317 | DOI:10.1080/02656736.2022.2034991 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 8, 2022 Category: Internal Medicine Authors: Gudny Jonsdottir Marie Beermann Annika Lundgren Cronsioe Klara Hasselrot Helena Kopp Kallner Source Type: research

Microwave ablation combined with anti-PD-1 therapy enhances systemic antitumor immunity in a multitumor murine model of Hepa1-6
CONCLUSIONS: The combination of MWA and anti-PD-1 therapy resulted in the inhibition of distant tumor growth and the construction of a systemic anti-tumor immune environment that can reduce recurrence.PMID:35129044 | DOI:10.1080/02656736.2022.2032406 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 7, 2022 Category: Internal Medicine Authors: Songjiang Huang Tongqiang Li Yang Chen Jiacheng Liu Yingliang Wang Chongtu Yang Chaoyang Wang Shuguang Ju Yaowei Bai Wei Yao Bin Xiong Source Type: research

Thermophysical and mechanical properties of biological tissues as a function of temperature: a systematic literature review
CONCLUSIONS: The thermophysical properties of soft tissues appear rather constant until 90 °C, with slight differences ascribable to tissues characteristics and measurement methods. Conversely, the information on mechanical properties is heterogeneous because most of the articles investigated different types of properties in different biological tissues. Furthermore, most of the experiments were conducted ex vivo; only a small percentage concerned in vivo studies. Limited recent information about the temperature dependence of metabolic heat and blood perfusion was observed.PMID:35129046 | DOI:10.1080/02656736.2022.2028908...
Source: International Journal of Hyperthermia - February 7, 2022 Category: Internal Medicine Authors: Leonardo Bianchi Fabiana Cavarzan Lucia Ciampitti Matteo Cremonesi Francesca Grilli Paola Saccomandi Source Type: research

Impact of UCP2 depletion on heat stroke-induced mitochondrial function in human umbilical vein endothelial cells
CONCLUSION: Our results indicate that UCP2 protects against HS-induced vascular endothelial damage and that it enhances mitochondrial function. These findings reveal that UCP2 can be a potential contributor to mechanism-based therapeutic strategies for HS.PMID:35129048 | DOI:10.1080/02656736.2022.2032846 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 7, 2022 Category: Internal Medicine Authors: Wei Huang Liangfeng Mao Weidang Xie Sumin Cai Qiaobing Huang Yanan Liu Zhongqing Chen Source Type: research