Ablation for oligometastatic colorectal carcinoma in extrahepatic, extrapulmonary sites
Int J Hyperthermia. 2022;39(1):633-638. doi: 10.1080/02656736.2021.1952318.ABSTRACTTreatment of metastatic colorectal carcinoma has evolved in the era of increasingly effective systemic therapies. Increasing survival rates provide opportunities for repeated focal therapies to be directed at limited metastatic disease. Surgical resection and other ablative therapies to eliminate oligometastases in the most common sites, namely liver and lung, have been proven to prolong survival. As such, patients develop additional sites of metastasis in the course of their disease, including adrenal, peritoneal, nodal, and skeletal metast...
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Scott M Thompson Brian T Welch A Nick Kurup Source Type: research

Volumetric analyses of ablation dimensions in microwave ablation for colorectal liver metastases
CONCLUSIONS: This study confirmed that factors beyond the applied ablation energy might affect volumetric ablation dimensions, resulting in poor predictability. Further clinical trials including tissue sampling are needed to relate physical tissue properties to ablation expansion.PMID:35465802 | DOI:10.1080/02656736.2021.1965224 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Iwan Paolucci Simeon J S Ruiter Jacob Freedman Daniel Candinas Koert P de Jong Stefan Weber Pascale Tinguely Source Type: research

Contemporary evidence on colorectal liver metastases ablation: toward a paradigm shift in locoregional treatment
Int J Hyperthermia. 2022;39(1):649-663. doi: 10.1080/02656736.2021.1970245.ABSTRACTImage-guided percutaneous ablation techniques represent an attractive local therapy for the treatment of colorectal liver metastases (CLM) given its low risk of severe complications, which allows for early initiation of adjuvant therapies and spare functional liver parenchyma, allowing repeated treatments at the time of recurrence. However, ablation does not consistently achieve similar oncological outcomes to surgery, with the latter being currently considered the first-line local treatment modality in international guidelines. Recent appli...
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Yuan-Mao Lin Reto Bale Kristy K Brock Bruno C Odisio Source Type: research

Shaping the future of microwave tumor ablation: a new direction in precision and control of device performance
Int J Hyperthermia. 2022;39(1):664-674. doi: 10.1080/02656736.2021.1991012.ABSTRACTMicrowave ablation (MWA) is becoming an increasingly important minimally invasive treatment option for localized tumors in many organ systems due to recent advancements in microwave technology that have conferred many advantages over other tumor ablation modalities. Despite these improvements in technology and development of applicators for site-specific tumor applications, the vast majority of commercially available MWA applicators are generally designed to create large-volume, symmetric, ellipsoid or spherically-shaped treatment zones and ...
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Austin Pfannenstiel Jason Iannuccilli Francois H Cornelis Damian E Dupuy Warren L Beard Punit Prakash Source Type: research

Yttrium-90 for colorectal liver metastasis - the promising role of radiation segmentectomy as an alternative local cure
Int J Hyperthermia. 2022;39(1):620-626. doi: 10.1080/02656736.2021.1933215.ABSTRACTThe majority of patients with metastatic colorectal cancer (CRC) to the liver are not amenable to curative-intent surgery or thermal ablation; there is a need for alternative locoregional therapies to control oligometastatic liver disease. Sequential lobar Yttrium-90 (Y90) radioembolization has demonstrated favorable results in the salvage setting for CRC patients with liver only or liver-dominant metastatic disease, but the role of Y90 in earlier-stage disease has not shown to be as promising. Recently, radiation segmentectomy, the super se...
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Pouya Entezari Ahmed Gabr Riad Salem Robert J Lewandowski Source Type: research

Molecular imaging in management of colorectal metastases by the interventional oncologist
Int J Hyperthermia. 2022;39(1):675-681. doi: 10.1080/02656736.2021.1998657.ABSTRACTInterventional oncologists provide several effective treatment options for patients with metastatic colorectal cancer (mCRC), including embolization and ablation-based techniques. Molecular imaging methods such as positron emission tomography (PET) can play an important role in managing mCRC patients. In this review, we aim to highlight the role of molecular imaging in mCRC management by interventional oncologists including: initial staging and pretreatment planning; predicting molecular subtypes, prognosis, and treatment outcomes; intraproc...
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Stephen Hunt Alireza Zandifar Abass Alavi Source Type: research

Thromboelastography maximum amplitude as an early predictor of disseminated intravascular coagulation in patients with heatstroke
CONCLUSIONS: MA < 45.4 mm in patients with heatstroke may predict elevated risk of DIC. HighlightsPatients with heatstroke-induced disseminated intravascular coagulation (DIC) has high mortality.A retrospective, single-center study was performed to investigate the ability of thromboelastography (TEG) to predict DIC associated with heatstroke.The maximum amplitude (MA) value of TEG decreased significantly with the increase of DIC score.MA < 45.4 mm was firstly demonstrated to an independent predictor of heatstroke-induced DIC.PMID:35465816 | DOI:10.1080/02656736.2022.2066206 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Longping He Qingwei Lin Lincui Zhong Qingbo Zeng Jingchun Song Source Type: research

Stereotactic body radiation therapy for colorectal liver metastases
Int J Hyperthermia. 2022;39(1):611-619. doi: 10.1080/02656736.2021.1923836.ABSTRACTMultidisciplinary case discussion of patients with colorectal liver metastases (CRLM) has led to improved selection of more complex patients with the oligometastatic disease for treatment with surgical resection, locally ablative therapy or a combination of local modalities to improve the therapeutic ratio in patients with CRLM. Stereotactic body radiation therapy (SBRT) is a noninvasive local therapy with a potential role in the management of oligometastatic CRLM and may be considered as an alternate choice to other locally ablative therapi...
Source: International Journal of Hyperthermia - April 25, 2022 Category: Internal Medicine Authors: Issa Mohamad Aisling Barry Laura Dawson Ali Hosni Source Type: research

System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance
CONCLUSIONS: We have developed a system for delivering microwave ablation to subcutaneous tumors in small animals under MRIT guidance and demonstrated its performance in-vivo.PMID:35435078 | DOI:10.1080/02656736.2022.2061727 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 18, 2022 Category: Internal Medicine Authors: Jan Sebek Tej B Shrestha Matthew T Basel Faraz Chamani Nooshin Zeinali Ivina Mali Macy Payne Sarah A Timmerman Pegah Faridi Marla Pyle Martin O'Halloran M Conall Dennedy Stefan H Bossmann Punit Prakash Source Type: research

Radiomics analysis of ultrasound to predict recurrence of hepatocellular carcinoma after microwave ablation
CONCLUSION: We developed and validated a radiomics model to predict HCC recurrence and HCC differentiation, which could also acquire pathological information in a noninvasive manner.KEY RESULTSA hepatocellular carcinoma (HCC) prognostic prediction model was developed and validated by convolutional neural network (CNN) ResNet 18-based gray-scale ultrasound (US).A differentiation of HCC prediction model was developed for preoperative prediction avoiding invasive operation.Compared with Pyradiomics, CNN ResNet was more suitable for extracting information from US images.PMID:35435082 | DOI:10.1080/02656736.2022.2062463 (Source...
Source: International Journal of Hyperthermia - April 18, 2022 Category: Internal Medicine Authors: Jia-Peng Wu Wen-Zhen Ding Yu-Ling Wang Sisi Liu Xiao-Qian Zhang Qi Yang Wen-Jia Cai Xiao-Ling Yu Fang-Yi Liu Dexing Kong Hui Zhong Jie Yu Ping Liang Source Type: research

System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance
CONCLUSIONS: We have developed a system for delivering microwave ablation to subcutaneous tumors in small animals under MRIT guidance and demonstrated its performance in-vivo.PMID:35435078 | DOI:10.1080/02656736.2022.2061727 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 18, 2022 Category: Internal Medicine Authors: Jan Sebek Tej B Shrestha Matthew T Basel Faraz Chamani Nooshin Zeinali Ivina Mali Macy Payne Sarah A Timmerman Pegah Faridi Marla Pyle Martin O'Halloran M Conall Dennedy Stefan H Bossmann Punit Prakash Source Type: research

Radiomics analysis of ultrasound to predict recurrence of hepatocellular carcinoma after microwave ablation
CONCLUSION: We developed and validated a radiomics model to predict HCC recurrence and HCC differentiation, which could also acquire pathological information in a noninvasive manner.KEY RESULTSA hepatocellular carcinoma (HCC) prognostic prediction model was developed and validated by convolutional neural network (CNN) ResNet 18-based gray-scale ultrasound (US).A differentiation of HCC prediction model was developed for preoperative prediction avoiding invasive operation.Compared with Pyradiomics, CNN ResNet was more suitable for extracting information from US images.PMID:35435082 | DOI:10.1080/02656736.2022.2062463 (Source...
Source: International Journal of Hyperthermia - April 18, 2022 Category: Internal Medicine Authors: Jia-Peng Wu Wen-Zhen Ding Yu-Ling Wang Sisi Liu Xiao-Qian Zhang Qi Yang Wen-Jia Cai Xiao-Ling Yu Fang-Yi Liu Dexing Kong Hui Zhong Jie Yu Ping Liang Source Type: research

System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance
CONCLUSIONS: We have developed a system for delivering microwave ablation to subcutaneous tumors in small animals under MRIT guidance and demonstrated its performance in-vivo.PMID:35435078 | DOI:10.1080/02656736.2022.2061727 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 18, 2022 Category: Internal Medicine Authors: Jan Sebek Tej B Shrestha Matthew T Basel Faraz Chamani Nooshin Zeinali Ivina Mali Macy Payne Sarah A Timmerman Pegah Faridi Marla Pyle Martin O'Halloran M Conall Dennedy Stefan H Bossmann Punit Prakash Source Type: research

Radiomics analysis of ultrasound to predict recurrence of hepatocellular carcinoma after microwave ablation
CONCLUSION: We developed and validated a radiomics model to predict HCC recurrence and HCC differentiation, which could also acquire pathological information in a noninvasive manner.KEY RESULTSA hepatocellular carcinoma (HCC) prognostic prediction model was developed and validated by convolutional neural network (CNN) ResNet 18-based gray-scale ultrasound (US).A differentiation of HCC prediction model was developed for preoperative prediction avoiding invasive operation.Compared with Pyradiomics, CNN ResNet was more suitable for extracting information from US images.PMID:35435082 | DOI:10.1080/02656736.2022.2062463 (Source...
Source: International Journal of Hyperthermia - April 18, 2022 Category: Internal Medicine Authors: Jia-Peng Wu Wen-Zhen Ding Yu-Ling Wang Sisi Liu Xiao-Qian Zhang Qi Yang Wen-Jia Cai Xiao-Ling Yu Fang-Yi Liu Dexing Kong Hui Zhong Jie Yu Ping Liang Source Type: research

System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance
CONCLUSIONS: We have developed a system for delivering microwave ablation to subcutaneous tumors in small animals under MRIT guidance and demonstrated its performance in-vivo.PMID:35435078 | DOI:10.1080/02656736.2022.2061727 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 18, 2022 Category: Internal Medicine Authors: Jan Sebek Tej B Shrestha Matthew T Basel Faraz Chamani Nooshin Zeinali Ivina Mali Macy Payne Sarah A Timmerman Pegah Faridi Marla Pyle Martin O'Halloran M Conall Dennedy Stefan H Bossmann Punit Prakash Source Type: research