High burden and diversity of carbapenemase-producing Enterobacterales observed in wastewater of a tertiary care hospital in Germany
In this study, we investigated the diversity and epidemiology of MRE in the wastewater of a large tertiary care hospital. Wastewater samples were collected for a four-day period and tested for the presence of Enterobacterales resistant to 3rd gen. cephalosporins. Representative isolates were further characterized by whole genome sequencing. In 120 β-glucuronidase-producing isolates, 68 Escherichia coli and, interestingly, also 52 Citrobacter freundii were identified. In 120 β-glucosidase-producing isolates 45 Serratia marcescens, 34 Klebsiella oxytoca, 32 Enterobacter cloacae and 9 Klebsiella pneumoniae were observed. Fo...
Source: International Journal of Hygiene and Environmental health - April 7, 2022 Category: Environmental Health Authors: Laura Carlsen Henning B üttner Martin Christner Gefion Franke Daniela Indenbirken Birte Knobling Marc L ütgehetmann Johannes Knobloch Source Type: research

High burden and diversity of carbapenemase-producing Enterobacterales observed in wastewater of a tertiary care hospital in Germany
In this study, we investigated the diversity and epidemiology of MRE in the wastewater of a large tertiary care hospital. Wastewater samples were collected for a four-day period and tested for the presence of Enterobacterales resistant to 3rd gen. cephalosporins. Representative isolates were further characterized by whole genome sequencing. In 120 β-glucuronidase-producing isolates, 68 Escherichia coli and, interestingly, also 52 Citrobacter freundii were identified. In 120 β-glucosidase-producing isolates 45 Serratia marcescens, 34 Klebsiella oxytoca, 32 Enterobacter cloacae and 9 Klebsiella pneumoniae were observed. Fo...
Source: International Journal of Hygiene and Environmental health - April 7, 2022 Category: Environmental Health Authors: Laura Carlsen Henning B üttner Martin Christner Gefion Franke Daniela Indenbirken Birte Knobling Marc L ütgehetmann Johannes Knobloch Source Type: research

Cancer mortality and chemical exposure in a retrospective zinc and lead smelter cohort: A 48-year follow-up
CONCLUSION: Including occupational exposure to numerous toxic agents other than lead in this study of smelter mortality has made it possible to identify associations between different toxic agents and cancers, opening up new avenues for future research.PMID:35385816 | DOI:10.1016/j.ijheh.2022.113955 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 6, 2022 Category: Environmental Health Authors: Ariane Leroyer Harry Gomajee Romain Leroy Muriel Mazzuca Bruno Leleu Catherine Nisse Source Type: research

Cancer mortality and chemical exposure in a retrospective zinc and lead smelter cohort: A 48-year follow-up
CONCLUSION: Including occupational exposure to numerous toxic agents other than lead in this study of smelter mortality has made it possible to identify associations between different toxic agents and cancers, opening up new avenues for future research.PMID:35385816 | DOI:10.1016/j.ijheh.2022.113955 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 6, 2022 Category: Environmental Health Authors: Ariane Leroyer Harry Gomajee Romain Leroy Muriel Mazzuca Bruno Leleu Catherine Nisse Source Type: research

Estimating cobalt exposure in respirable dust from cobalt in inhalable dust
In this study, 639 parallel measurements of cobalt concentrations in inhalable (cI(Co)) and respirable dust fractions (cR(Co)) were extracted from the non-public exposure database MEGA (Measurement data relating to workplace exposure to hazardous substances, maintained at the Institute for Occupational Safety and Health of the German Social Accident Insurance) and investigated by regression analysis. For the whole dataset regression shows high quality measures (correlation coefficient R = 0.888, adjusted coefficient of determination adj. R2 = 0.788 - R2 is adjusted to sample size). Further description of the data is achiev...
Source: International Journal of Hygiene and Environmental health - April 4, 2022 Category: Environmental Health Authors: Cornelia Wippich Dorothea Koppisch Katrin Pitzke Dietmar Breuer Source Type: research

Estimating cobalt exposure in respirable dust from cobalt in inhalable dust
In this study, 639 parallel measurements of cobalt concentrations in inhalable (cI(Co)) and respirable dust fractions (cR(Co)) were extracted from the non-public exposure database MEGA (Measurement data relating to workplace exposure to hazardous substances, maintained at the Institute for Occupational Safety and Health of the German Social Accident Insurance) and investigated by regression analysis. For the whole dataset regression shows high quality measures (correlation coefficient R = 0.888, adjusted coefficient of determination adj. R2 = 0.788 - R2 is adjusted to sample size). Further description of the data is achiev...
Source: International Journal of Hygiene and Environmental health - April 4, 2022 Category: Environmental Health Authors: Cornelia Wippich Dorothea Koppisch Katrin Pitzke Dietmar Breuer Source Type: research

Association between greenspace and lung function in Italian children-adolescents
CONCLUSION: Quantile regression techniques may provide new insights into the evaluation of the association between greenspace exposure and lung function in children-adolescents, showing substantially heterogeneous effects from lower to higher quantiles of spirometry parameters. These results may help implementing policies for planning sustainable housing and surrounding greenspaces.PMID:35367927 | DOI:10.1016/j.ijheh.2022.113947 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 3, 2022 Category: Environmental Health Authors: Giovanna Cilluffo Giuliana Ferrante Salvatore Fasola Gaspare Drago Silvia Ruggieri Giovanni Viegi Fabio Cibella Stefania La Grutta Source Type: research

Association between greenspace and lung function in Italian children-adolescents
CONCLUSION: Quantile regression techniques may provide new insights into the evaluation of the association between greenspace exposure and lung function in children-adolescents, showing substantially heterogeneous effects from lower to higher quantiles of spirometry parameters. These results may help implementing policies for planning sustainable housing and surrounding greenspaces.PMID:35367927 | DOI:10.1016/j.ijheh.2022.113947 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 3, 2022 Category: Environmental Health Authors: Giovanna Cilluffo Giuliana Ferrante Salvatore Fasola Gaspare Drago Silvia Ruggieri Giovanni Viegi Fabio Cibella Stefania La Grutta Source Type: research

What is required to combine human biomonitoring and health surveys?
Int J Hyg Environ Health. 2022 Mar 29;242:113964. doi: 10.1016/j.ijheh.2022.113964. Online ahead of print.ABSTRACTObtaining holistic information about health and health determinants at the population level should also include data on environmental risk factors of health. So far, only a few countries have combined, at the national level, health and human biomonitoring (HBM) surveys to collect extensive information on health, lifestyles, biological health determinants and environmental exposures. This paper will provide guidelines on how to combine health and HBM surveys and what is the added value of doing so. Health and HB...
Source: International Journal of Hygiene and Environmental health - April 1, 2022 Category: Environmental Health Authors: Hanna Tolonen Sonja Moore Dominik Lermen Ana Virgolino Lisbeth E Knudsen Anna-Maria Andersson Lo ïc Rambaud Carla Ancona Marike Kolossa-Gehring Source Type: research

Temporal trend and cross-sectional characterization of urinary concentrations of glyphosate in Japanese children from 2006 to 2015
CONCLUSION: This study revealed that Gly exposure trends show an increase between 2006 and 2015, and that season and gender were not the exposure-determining factors. Overall, urinary concentrations of Gly were comparable with studies from other countries.PMID:35364446 | DOI:10.1016/j.ijheh.2022.113963 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 1, 2022 Category: Environmental Health Authors: Hiroshi Nomura Risa Hamada Keiko Wada Isao Saito Nanami Nishihara Yugo Kitahara Satoru Watanabe Kunihiko Nakane Chisato Nagata Takaaki Kondo Michihiro Kamijima Jun Ueyama Source Type: research

What is required to combine human biomonitoring and health surveys?
Int J Hyg Environ Health. 2022 Mar 29;242:113964. doi: 10.1016/j.ijheh.2022.113964. Online ahead of print.ABSTRACTObtaining holistic information about health and health determinants at the population level should also include data on environmental risk factors of health. So far, only a few countries have combined, at the national level, health and human biomonitoring (HBM) surveys to collect extensive information on health, lifestyles, biological health determinants and environmental exposures. This paper will provide guidelines on how to combine health and HBM surveys and what is the added value of doing so. Health and HB...
Source: International Journal of Hygiene and Environmental health - April 1, 2022 Category: Environmental Health Authors: Hanna Tolonen Sonja Moore Dominik Lermen Ana Virgolino Lisbeth E Knudsen Anna-Maria Andersson Lo ïc Rambaud Carla Ancona Marike Kolossa-Gehring Source Type: research

Temporal trend and cross-sectional characterization of urinary concentrations of glyphosate in Japanese children from 2006 to 2015
CONCLUSION: This study revealed that Gly exposure trends show an increase between 2006 and 2015, and that season and gender were not the exposure-determining factors. Overall, urinary concentrations of Gly were comparable with studies from other countries.PMID:35364446 | DOI:10.1016/j.ijheh.2022.113963 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - April 1, 2022 Category: Environmental Health Authors: Hiroshi Nomura Risa Hamada Keiko Wada Isao Saito Nanami Nishihara Yugo Kitahara Satoru Watanabe Kunihiko Nakane Chisato Nagata Takaaki Kondo Michihiro Kamijima Jun Ueyama Source Type: research

Pollen allergy: Developing multi-sectorial strategies for its prevention and control in lower and middle-income countries
Int J Hyg Environ Health. 2022 Mar 22;242:113951. doi: 10.1016/j.ijheh.2022.113951. Online ahead of print.ABSTRACTPollen allergy is considered a major public health problem that causes morbidity and subsequently affects a patient's quality of life. Pollen due to their large size cannot enter the thoracic regions of the respiratory tract but can affect the nasopharyngeal mucous membrane. At the same time, the submicronic-pollen particles can act as respirable particles reaching deeper into the upper airways leading to exacerbation of asthma, chronic obstructive pulmonary disease (COPD) and other allergic reactions. Based on...
Source: International Journal of Hygiene and Environmental health - March 25, 2022 Category: Environmental Health Authors: Khaiwal Ravindra Akshi Goyal Suman Mor Source Type: research

Declining semen quality and polybrominated diphenyl ethers (PBDEs): Review of the literature to support the derivation of a reference dose for a mixture risk assessment
Int J Hyg Environ Health. 2022 Mar 22;242:113953. doi: 10.1016/j.ijheh.2022.113953. Online ahead of print.ABSTRACTTo support a mixture risk assessment for chemicals that interfere with male reproductive health, we reviewed the literature to identify studies of polybrominated diphenyl ethers (PBDEs) and poor semen quality. Several epidemiological studies have shown associations of PBDE exposures with declining semen quality, non-descending testes and penile malformations. In rodent studies, poor semen quality, changes in testosterone levels and reproductive tissues have been observed. In vitro studies with reporter gene con...
Source: International Journal of Hygiene and Environmental health - March 25, 2022 Category: Environmental Health Authors: Sibylle Ermler Andreas Kortenkamp Source Type: research

Pollen allergy: Developing multi-sectorial strategies for its prevention and control in lower and middle-income countries
Int J Hyg Environ Health. 2022 Mar 22;242:113951. doi: 10.1016/j.ijheh.2022.113951. Online ahead of print.ABSTRACTPollen allergy is considered a major public health problem that causes morbidity and subsequently affects a patient's quality of life. Pollen due to their large size cannot enter the thoracic regions of the respiratory tract but can affect the nasopharyngeal mucous membrane. At the same time, the submicronic-pollen particles can act as respirable particles reaching deeper into the upper airways leading to exacerbation of asthma, chronic obstructive pulmonary disease (COPD) and other allergic reactions. Based on...
Source: International Journal of Hygiene and Environmental health - March 25, 2022 Category: Environmental Health Authors: Khaiwal Ravindra Akshi Goyal Suman Mor Source Type: research