Time trend of the exposure to geraniol in 24-h urine samples derived from the German Environmental Specimen Bank from 2004 to 2018
Int J Hyg Environ Health. 2021 Nov 10;239:113880. doi: 10.1016/j.ijheh.2021.113880. Online ahead of print.ABSTRACTGeraniol (trans-3,7-dimethyl-2,6-octadiene-1-ol) is an acyclic isoprenoid monoterpene with a widespread use as fragrance in consumer products, agrochemicals and pharmaceuticals. The class of terpene chemicals has been associated with varying sensitizing potencies. A recently developed sensitive LC- MS/MS method for the analysis of geraniol metabolites was further improved and validated for the two metabolites, 8-carboxygeraniol and Hildebrandt acid. The successfully validated method was applied to 250 urine sam...
Source: International Journal of Hygiene and Environmental health - November 13, 2021 Category: Environmental Health Authors: Nikola Pluym Markus St öckelhuber Till Weber Gerhard Scherer Max Scherer Marike Kolossa-Gehring Source Type: research

Time trend of the exposure to geraniol in 24-h urine samples derived from the German Environmental Specimen Bank from 2004 to 2018
Int J Hyg Environ Health. 2021 Nov 10;239:113880. doi: 10.1016/j.ijheh.2021.113880. Online ahead of print.ABSTRACTGeraniol (trans-3,7-dimethyl-2,6-octadiene-1-ol) is an acyclic isoprenoid monoterpene with a widespread use as fragrance in consumer products, agrochemicals and pharmaceuticals. The class of terpene chemicals has been associated with varying sensitizing potencies. A recently developed sensitive LC- MS/MS method for the analysis of geraniol metabolites was further improved and validated for the two metabolites, 8-carboxygeraniol and Hildebrandt acid. The successfully validated method was applied to 250 urine sam...
Source: International Journal of Hygiene and Environmental health - November 13, 2021 Category: Environmental Health Authors: Nikola Pluym Markus St öckelhuber Till Weber Gerhard Scherer Max Scherer Marike Kolossa-Gehring Source Type: research

Effects of SNPs in SOD2 and SOD3 interacted with fluoride exposure on the susceptibility of dental fluorosis
Int J Hyg Environ Health. 2021 Nov 2;239:113879. doi: 10.1016/j.ijheh.2021.113879. Online ahead of print.ABSTRACTA total of 649 children aged 7-13 years of age were recruited in a cross-sectional study in Tongxu County, China (2017) to assess the effects of interaction between single nucleotide polymorphisms (SNPs) in SOD2 and SOD3 gene and fluoride exposure on dental fluorosis (DF) status. Associations between biomarkers and DF status were evaluated. Logistic regression suggested that the risk of DF in children with rs10370 GG genotype and rs5746136 TT genotype was 1.89-fold and 1.72-fold than that in children with TT/CC ...
Source: International Journal of Hygiene and Environmental health - November 11, 2021 Category: Environmental Health Authors: Yuhui Du Xiaoli Fu Jing Jin Zhiyuan Li Kaihong Xu Meng Guo Xiangbo Hou Zichen Feng Limin Ding Yongxiang Gong Bin Liu Fangfang Yu Guoyu Zhou Yue Ba Source Type: research

Effects of SNPs in SOD2 and SOD3 interacted with fluoride exposure on the susceptibility of dental fluorosis
Int J Hyg Environ Health. 2021 Nov 2;239:113879. doi: 10.1016/j.ijheh.2021.113879. Online ahead of print.ABSTRACTA total of 649 children aged 7-13 years of age were recruited in a cross-sectional study in Tongxu County, China (2017) to assess the effects of interaction between single nucleotide polymorphisms (SNPs) in SOD2 and SOD3 gene and fluoride exposure on dental fluorosis (DF) status. Associations between biomarkers and DF status were evaluated. Logistic regression suggested that the risk of DF in children with rs10370 GG genotype and rs5746136 TT genotype was 1.89-fold and 1.72-fold than that in children with TT/CC ...
Source: International Journal of Hygiene and Environmental health - November 11, 2021 Category: Environmental Health Authors: Yuhui Du Xiaoli Fu Jing Jin Zhiyuan Li Kaihong Xu Meng Guo Xiangbo Hou Zichen Feng Limin Ding Yongxiang Gong Bin Liu Fangfang Yu Guoyu Zhou Yue Ba Source Type: research

Exploring the relationship between metal exposure, BDNF, and behavior in adolescent males
CONCLUSION: Exposure to As and Cd was associated with BDNF gene DNA methylation BDNF gene and serum BDNF, respectively. Associations with DNA methylation may be attributable to a higher variability over time in circulating BDNF concentrations than in the methylation status of this gene. Caution should be taken when interpreting the results relating postnatal Pb and Hg to behavioral functioning. Further studies are needed to verify these findings.PMID:34757248 | DOI:10.1016/j.ijheh.2021.113877 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Andrea Rodr íguez-Carrillo Vicente Mustieles Shereen Cynthia D'Cruz Louis Legoff Fernando Gil Pablo Olmedo Iris Reina-P érez Antonio Mundo Marina Molina Fatima Smagulova Arthur David Carmen Freire Mariana F Fern ández Source Type: research

Long-term exposure to ambient nitrogen dioxide and ozone modifies systematic low-grade inflammation: The CHCN-BTH study
Int J Hyg Environ Health. 2021 Oct 29;239:113875. doi: 10.1016/j.ijheh.2021.113875. Online ahead of print.ABSTRACTThe potential effect of long-term exposure to ambient air pollutants on low-grade systematic inflammation has seldom been evaluated taking indoor air pollution and self-protection behaviors on smog days into account. A total of 24,346 participants at baseline were included to conduct a cross-sectional study. The annual (2016) average pollutant concentrations were assessed by air monitoring stations for PM2.5, PM10, SO2, NO2, O3 and CO. Associations between annual ambient air pollution and low-grade systematic i...
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Kuo Liu Han Cao Bingxiao Li Chunyue Guo Wei Zhao Xiaoyan Han Han Zhang Zhengfang Wang Naijun Tang Kaijun Niu Li Pan Huijing He Ze Cui Jixin Sun Guangliang Shan Ling Zhang Source Type: research

A new measure of hygiene inequality applied to urban-rural comparison
Int J Hyg Environ Health. 2021 Oct 29;239:113876. doi: 10.1016/j.ijheh.2021.113876. Online ahead of print.ABSTRACTAccess to hygiene services remains one of the most urgent challenges facing countries, especially low-income ones. This has become much more critical in the current context of the COVID-19 pandemic. The WHO/UNICEF Joint Monitoring Program globally monitors access to hygiene service levels. As data are in three parts with a constant sum and a positive value, they are compositional data. Inequality is monitored in disaggregated data; in the urban-rural case, this is done through a simple difference between the ur...
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Alejandro Quispe-Coica Agust í Pérez-Foguet Source Type: research

The mediating role of vascular inflammation in traffic-related air pollution associated changes in insulin resistance in healthy adults
CONCLUSION: Our results suggest that ambient traffic pollution exposure was capable of promoting insulin resistance possibly via generating vascular inflammation.PMID:34757311 | DOI:10.1016/j.ijheh.2021.113878 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Hongbing Xu Shengcong Liu Yang Wang Rongshan Wu Tieci Yi Tong Wang Yutong Zhu Jiakun Fang Yunfei Xie Qian Zhao Xiaoming Song Jie Chen Sanjay Rajagopaplan Robert D Brook Jianping Li Junji Cao Wei Huang Source Type: research

Exploring the relationship between metal exposure, BDNF, and behavior in adolescent males
CONCLUSION: Exposure to As and Cd was associated with BDNF gene DNA methylation BDNF gene and serum BDNF, respectively. Associations with DNA methylation may be attributable to a higher variability over time in circulating BDNF concentrations than in the methylation status of this gene. Caution should be taken when interpreting the results relating postnatal Pb and Hg to behavioral functioning. Further studies are needed to verify these findings.PMID:34757248 | DOI:10.1016/j.ijheh.2021.113877 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Andrea Rodr íguez-Carrillo Vicente Mustieles Shereen Cynthia D'Cruz Louis Legoff Fernando Gil Pablo Olmedo Iris Reina-P érez Antonio Mundo Marina Molina Fatima Smagulova Arthur David Carmen Freire Mariana F Fern ández Source Type: research

Long-term exposure to ambient nitrogen dioxide and ozone modifies systematic low-grade inflammation: The CHCN-BTH study
Int J Hyg Environ Health. 2021 Oct 29;239:113875. doi: 10.1016/j.ijheh.2021.113875. Online ahead of print.ABSTRACTThe potential effect of long-term exposure to ambient air pollutants on low-grade systematic inflammation has seldom been evaluated taking indoor air pollution and self-protection behaviors on smog days into account. A total of 24,346 participants at baseline were included to conduct a cross-sectional study. The annual (2016) average pollutant concentrations were assessed by air monitoring stations for PM2.5, PM10, SO2, NO2, O3 and CO. Associations between annual ambient air pollution and low-grade systematic i...
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Kuo Liu Han Cao Bingxiao Li Chunyue Guo Wei Zhao Xiaoyan Han Han Zhang Zhengfang Wang Naijun Tang Kaijun Niu Li Pan Huijing He Ze Cui Jixin Sun Guangliang Shan Ling Zhang Source Type: research

A new measure of hygiene inequality applied to urban-rural comparison
Int J Hyg Environ Health. 2021 Oct 29;239:113876. doi: 10.1016/j.ijheh.2021.113876. Online ahead of print.ABSTRACTAccess to hygiene services remains one of the most urgent challenges facing countries, especially low-income ones. This has become much more critical in the current context of the COVID-19 pandemic. The WHO/UNICEF Joint Monitoring Program globally monitors access to hygiene service levels. As data are in three parts with a constant sum and a positive value, they are compositional data. Inequality is monitored in disaggregated data; in the urban-rural case, this is done through a simple difference between the ur...
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Alejandro Quispe-Coica Agust í Pérez-Foguet Source Type: research

The mediating role of vascular inflammation in traffic-related air pollution associated changes in insulin resistance in healthy adults
CONCLUSION: Our results suggest that ambient traffic pollution exposure was capable of promoting insulin resistance possibly via generating vascular inflammation.PMID:34757311 | DOI:10.1016/j.ijheh.2021.113878 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Hongbing Xu Shengcong Liu Yang Wang Rongshan Wu Tieci Yi Tong Wang Yutong Zhu Jiakun Fang Yunfei Xie Qian Zhao Xiaoming Song Jie Chen Sanjay Rajagopaplan Robert D Brook Jianping Li Junji Cao Wei Huang Source Type: research

Long-term air pollution, noise, and structural measures of the Default Mode Network in the brain: Results from the 1000BRAINS cohort
CONCLUSION: Long-term AP and noise were not consistently associated with structural parameters of the DMN in the brain. While weak associations were present between AP exposure and cortical thinning of right hemispheric DMN regions, it remains unclear whether AP might influence DMN brain structure in a similar way as aging.PMID:34717183 | DOI:10.1016/j.ijheh.2021.113867 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - October 30, 2021 Category: Environmental Health Authors: Sarah Lucht Lina Glaubitz Susanne Moebus Sara Schramm Christiane Jockwitz Svenja Caspers Barbara Hoffmann Source Type: research

Climate variability and seasonal patterns of paediatric parainfluenza infections in the tropics: An ecological study in Singapore
CONCLUSIONS: This study demonstrates a close association between HPIV infection risk and tropical climate variability. The climate dependence and seasonal predictability of HPIV can inform the timing of community campaigns aimed at reducing infection risk and the development of hospital resources and climate adaption plans.PMID:34717184 | DOI:10.1016/j.ijheh.2021.113864 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - October 30, 2021 Category: Environmental Health Authors: Stacy Soh Liat Hui Loo Natasha Jamali Matthias Maiwald Joel Aik Source Type: research

Long-term air pollution, noise, and structural measures of the Default Mode Network in the brain: Results from the 1000BRAINS cohort
CONCLUSION: Long-term AP and noise were not consistently associated with structural parameters of the DMN in the brain. While weak associations were present between AP exposure and cortical thinning of right hemispheric DMN regions, it remains unclear whether AP might influence DMN brain structure in a similar way as aging.PMID:34717183 | DOI:10.1016/j.ijheh.2021.113867 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - October 30, 2021 Category: Environmental Health Authors: Sarah Lucht Lina Glaubitz Susanne Moebus Sara Schramm Christiane Jockwitz Svenja Caspers Barbara Hoffmann Source Type: research