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When Ovarian Cancer Is Not: Characterizing Nonovarian Cancer Pathology in a Laparoscopy-Based Triage System
This study sought to investigate and describe nonovarian cancer pathologies discovered during the systematic laparoscopic workup of presumed advanced ovarian cancer. Methods A retrospective cohort of patients with presumed advanced ovarian cancer (based on elevated CA125 and/or imaging) presenting to our center without confirmed pathologic diagnosis were identified and characterized. Patients without ovarian cancer on final pathology were described and compared with those with confirmed epithelial ovarian cancer using standard statistical methods. Results Nonovarian cancer was found in 26 (7.1%) of 365 cases over 3.5...
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Trends and Outcomes of Venous Thromboembolism in Hospitalized Patients With Ovarian Cancer: Results From Nationwide Inpatient Sample Database 2003 to 2011
Objective Venous thromboembolism (VTE) is a major cause of mortality and morbidity in hospitalized patients with malignancy. Nationwide Inpatient Sample database was analyzed to determine the trends in the rate of hospitalization and mortality from VTE in hospitalized ovarian cancer patients and assess its economic impact and resource utilization. Method We queried the 2003 to 2011 Nationwide Inpatient Sample database from Healthcare Cost and Utilization project (Agency of Healthcare Research and Quality) to identify all adults (age ≥18 years) ovarian cancer. Patients hospitalized with VTE as one of the top 3 discha...
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

The Diagnostic Accuracy of Human Epididymis Factor 4 for the Prediction of Optimal Debulking in Patients With Ovarian Cancer: A Meta-Analysis of Observational Studies
Conclusions Human epididymis factor-4 seems to be promising as a minimally invasive method to predict optimal cytoreduction among patients with ovarian cancer. However, interpretation of our findings should be approached with caution because of the significant heterogeneity of included studies. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Changes in the Management and Prognosis of Ovarian Cancer Due to the New FIGO and WHO Classifications: A Case Series Observational Descriptive Study. Seven Years of Follow-up
Conclusions The newly created WHO and FIGO classifications have improved the ability to predict the prognosis and consequently to change the therapeutic managements of patients with ovarian cancer. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Complete Resection Is Essential in the Surgical Treatment of Gestational Trophoblastic Neoplasia
Objective The aim of this study was to determine the utility of surgery in patients with gestational trophoblastic neoplasia (GTN). Materials and Methods We performed a retrospective institutional review board–approved analysis of all patients with GTN at a single institution from 1985 to 2015 and compared all patients who underwent surgery as definitive management for their disease to a matched cohort of those who did not. Kaplan-Meier curves were used to estimate progression-free survival (PFS) and overall survival (OS). Results Sixty-nine patients underwent a total of 94 surgeries as definitive treatment for G...
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Gestational Throphoblastic Neoplasia Source Type: research

Low-Risk Gestational Trophoblastic Neoplasia in Manitoba: Experience With Alternating Methotrexate and Dactinomycin
Conclusions Alternating methotrexate and dactinomycin is an effective treatment protocol for low-risk GTN, with high rates of primary cure and acceptable toxicity. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Gestational Throphoblastic Neoplasia Source Type: research

Letter From Editor October 2018
No abstract available (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Editorial Source Type: research

Vaginal Yolk Sac Tumors: Our Experiences and Results Erratum
No abstract available (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Erratum Source Type: research

A Clinical Evaluation of American Brachytherapy Society Consensus Guideline for Bulky Vaginal Mass in Gynecological Cancer
Objectives American Brachytherapy Society (ABS)-recommended interstitial brachytherapy (IBT) should be considered for bulky vaginal tumor thicker than 5 mm. The aim of this study was to evaluate the ABS consensus guideline for patients with severe vaginal invasion based on our long-term follow-up results. Methods/Materials The study included 7 patients with vaginal cancer and 14 patients with cervical cancer invading to the lower vagina. Based on prebrachytherapy magnetic resonance imaging findings, patients received intracavitary brachytherapy (ICT) for vaginal tumors 5 mm or less or IBT for vaginal tumors less than ...
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Radiation Therapy Source Type: research

Use of a Sentinel Lymph Node Biopsy Algorithm in a South African Population of Patients With Cervical Cancer and High Prevalence of Human Immunodeficiency Virus Infection
Conclusions The SLN algorithm is a feasible option for use in cervical cancer women with a high prevalence of HIV infection. The detection rate is generally lower, but in select subgroups of women, it was comparable to that reported elsewhere. This is the first report of the use of SLN biopsy in a substantial group of HIV-infected women. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Surgeons Corner Source Type: research

Predictors of Unplanned Reoperation for Ovarian Cancer Patients From the National Surgical Quality Improvement Program Database
Conclusions Efforts to reduce reoperation rates should focus on identifying high-risk patients by utilizing objective preoperative data. Optimizing their medical status prior to surgery may decrease the reoperation rate in patients with ovarian cancer, thereby improving outcomes and providing a probable cost benefit. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Surgeons Corner Source Type: research

Ghost Ileostomy in Advanced Ovarian Cancer: A Reliable Option
Conclusions To the extent of our knowledge, this is the first study in which GI has been performed for the treatment of patients with ovarian cancer. Ghost ileostomy represents a real option that may reduce the number of ileostomies performed in ovarian cancer without increasing the morbimortality. Ghost ileostomy presents the advantages of DI while avoiding its drawbacks. It also seems to be a safe, feasible, and reproducible technique that does not add significant costs to the surgery. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Surgeons Corner Source Type: research

Do the Residual Lung Lesions Threaten Gestational Trophoblastic Neoplasia Patients?
Conclusions After the achievement of normalized β-hCG by sufficient chemotherapy, residual lung lesions do not alter the prognosis of patients with GTN, even if the patients are with other recurrent risk factors. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Gestational Trophoblastic Neoplasia Source Type: research

Correlation of Isotope Count With Sentinel Node Positivity in Vulvar Cancer
Conclusions The highest isotope count does not reliably detect the positive SLN in vulvar cancer. To prevent mostly fatal groin recurrences, surgeons should continue to remove all SLN accumulating relevant radioactive tracer over background activity. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Vulvar Cancer Source Type: research

The Influence of Chemotherapy-Induced Peripheral Neuropathy on Quality of Life of Gynecologic Cancer Survivors
Objective The aim of this observational study was to investigate correlations between long-term chemotherapy-induced peripheral neurotoxicity (CIPN) and quality of life (physical well-being, social well-being, emotional well-being, and functional well-being [FWB]) among survivors of gynecologic cancer (GC). Methods We aimed to assess the correlation of quality of life and long-term CIPN with the temporal change in recurrence-free GC survival. Questionnaire responses and clinical data of 259 GC survivors were collected and assessed according to treatment received. The χ2 test was used to determine the significance of ...
Source: International Journal of Gynecological Cancer - August 28, 2018 Category: Cancer & Oncology Tags: Quality of Life Source Type: research