Histopathological features of skin lesions in patients affected by non ‐ulcerated or atypical cutaneous leishmaniasis in Honduras, Central America
SummaryIn Honduras visceral leishmaniasis and non ‐ulcerated or atypical cutaneous leishmaniasis (NUCL) are caused by the speciesLeishmania (L.) infantum chagasi. NUCL is the most common clinical form in the southern regions of the country, mainly affecting the young. In view of the lack of knowledge about the pathogenesis of the disease pattern caused byL. (L) infantum chagasi in individuals affected by NUCL, the aim of the present study was to describe in detail the histopathological features of the skin lesion caused by the parasite. Biopsies from human NUCL lesions with a positive parasitological diagnosis were colle...
Source: International Journal of Experimental Pathology - November 27, 2018 Category: Pathology Authors: Carmen Maria Sandoval Pacheco, Gabriela Venicia Araujo Flores, Aurea Favero Ferreira, Wilfredo Sosa Ochoa, V ânia Lúcia Ribeiro da Matta, Concepción Zúniga Valeriano, Carlos Eduardo Pereira Corbett, Marcia Dalastra Laurenti Tags: ORIGINAL ARTICLE Source Type: research

Nitrogen ‐containing bisphosphonate therapy—Part II: Assessment of alveolar bone tissue inflammatory response in rats—A blind randomized controlled trial
This study aimed to evaluate the alveolar bone tissue inflammatory response in rats undergoing zoledronic acid therapy. The study sample was composed of 28Wistar rats. Animals from the test group GTa received a weekly intraperitoneal dose of 0.2  mg/kg of zoledronic acid for 3 weeks, while test group GTb received the same dose for 8 weeks. A physiological saline dose, equivalent to that of the medication, was administered to the controls in groups GCa and GCb. A defect was created in the dental crown of the lower first molars using a dri ll to simulate pulp and periapical injury. Data were evaluated regarding image grey...
Source: International Journal of Experimental Pathology - November 20, 2018 Category: Pathology Authors: Viviane N. Pacheco, Renan Langie, Jules R. D. Benfica, J éssica C. Munaretto, Adriana Etges, Deise Ponzoni, Edela Puricelli Tags: ORIGINAL ARTICLE Source Type: research

Systemic alterations induced by phospholipase A2, BmooTX ‐I, isolated from Bothrops moojeni snake venom
SummaryOphidic accidents are among the problems of public health in Brazil. The components from bothropic venom are responsible for many systemic clinical complications resulting from envenomation. The present work aimed to analyse the systemic changes induced in mice after intraperitoneal administration of BmooTX ‐I, a myotoxic acidic phospholipase A2 isolated fromBothrops moojeni venom. Urinalysis was performed and the following plasma biochemical markers were documented: urea, creatinine and uric acid (renal function); glucose and amylase (pancreatic function); alanine aminotransferase, alkaline phosphatase and gamma ...
Source: International Journal of Experimental Pathology - November 20, 2018 Category: Pathology Authors: Kellen Cristina Torres Costa, Bruna Barbosa Sousa, Edigar Henrique Vaz Dias, D éborah Fernanda da Cunha Pereira, Mariana Santos Matias, Wilson Júnior Oliveira, Antônio Vicente Mundim, Carla Cristine Neves Mamede, Luíz Fernando Moreira Izidoro, Tags: ORIGINAL ARTICLE Source Type: research

Omega ‐6 fatty acids down‐regulate matrix metalloproteinase expression in a coronary heart disease‐induced rat model
SummaryThe present study investigated the therapeutic potential of omega ‐6 fatty acids, according to their effects on antioxidant markers and matrix metalloproteinases (MMPs), in coronary heart disease‐induced rats. Rats were grouped into group I (sham control), group II (control), group III (0.5 g/kg bwt of omega‐6 fatty acids) and group IV (1 g/kg bwt of omega ‐6 fatty acids). Reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD), reduced glutathione (GSH), catalase, glutathione peroxidase (Gpx) and acetylcholinesterase (AChE) enzyme activities were determined. ROS and MDA were subst...
Source: International Journal of Experimental Pathology - November 15, 2018 Category: Pathology Authors: Nihong Lu, Yingrong Du, Haiyuan Li, Yu Luo, Bing Ouyang, Yangjun Chen, Yongrui Yang, Lixia Yang Tags: ORIGINAL ARTICLE Source Type: research

Can the indicators of chronic ethanol consumption be minimized by a continuous flaxseed intake?
International Journal of Experimental Pathology, EarlyView. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - October 19, 2018 Category: Pathology Authors: Juliana Tomaz Pacheco Latini, Gabriela C âmara Vicente, Luis Guillermo Coca Velarde, Hildebrando Gomes Benedicto, Ângela Castro Resende, Michelle Teixeira Teixeira, Kátia Calvi Lenzi Almeida, Gilson Teles Boaventura Source Type: research

Cellular profile of primary molars with pulp necrosis after treatment with antibiotic paste
International Journal of Experimental Pathology, EarlyView. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - October 16, 2018 Category: Pathology Authors: L úcia de Fátima Almeida de Deus Moura, Marina de Deus Moura de Lima, Cacilda Castelo Branco Lima, Ana Victória Lopes Bandeira, Marcoeli Silva de Moura, Airton Mendes Conde Júnior, Márcia dos Santos Rizzo Source Type: research

Hydroxymethylnitrofurazone treatment in indeterminate form of chronic Chagas disease: Reduced intensity of tissue parasitism and inflammation —A histopathological study
International Journal of Experimental Pathology, EarlyView. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - October 15, 2018 Category: Pathology Authors: Cau ê B. Scarim, Cleverton R. Andrade, João A. Rosa, Jean L. Santos, Chung M. Chin Source Type: research

Issue Information
International Journal of Experimental Pathology,Volume 99, Issue 4, Page 147-149, August 2018. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - September 26, 2018 Category: Pathology Source Type: research

Hyperactivation of the hypothalamo ‐pituitary‐adrenocortical axis in streptozotocin‐diabetic gerbils (Gerbillus gerbillus)
International Journal of Experimental Pathology,Volume 99, Issue 4, Page 172-179, August 2018. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - September 26, 2018 Category: Pathology Authors: Soumia Hammadi, Owen Chan, Mohamed Abdellali, Maha Medjerab, Hadjer Agoun, Zineb Bellahreche, Ali Khalkhal, Yasmina Dahmani Source Type: research

Histopathological changes in androgenized ovaries are recovered by melatonin treatment
International Journal of Experimental Pathology,Volume 99, Issue 4, Page 158-171, August 2018. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - September 26, 2018 Category: Pathology Authors: Bianca R. Souza, Luiz Gustavo Almeida Chuffa, Vin ícius Augusto Simão, Isabel C. C. Camargo Source Type: research

Adaptive growth changes in the liver remnant are affected by the size of hepatectomy in rats
International Journal of Experimental Pathology, EarlyView. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - September 10, 2018 Category: Pathology Authors: Michelle Meier , Kasper Jarlhelt Andersen , Anders Riegels Knudsen , Jens Randel Nyengaard , Stephen Hamilton ‐Dutoit , Frank Viborg Mortensen Source Type: research

Neuroprotective effect of carnosine in the olfactory bulb after vanadium inhalation in a mouse model
International Journal of Experimental Pathology, EarlyView. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - September 10, 2018 Category: Pathology Authors: Laura Col ín‐Barenque , Patricia Bizarro‐Nevares , Adriana González Villalva , Jose Pedraza‐Chaverri , Omar Noel Medina‐Campos , Ruben Jimenez‐Martínez , Daniela S. Rodríguez‐Rangel , Stefanie Reséndiz , Teresa I. Fortoul Source Type: research

Association of miR ‐1247‐5p expression with clinicopathological parameters and prognosis in breast cancer
International Journal of Experimental Pathology, EarlyView. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - September 3, 2018 Category: Pathology Authors: Peng Zhang , Changsheng Fan , Jun Du , Xueli Mo , Qikang Zhao Source Type: research

A histomorphometric classification system for normal and inflamed mouse duodenum —Quali‐quantitative approach
International Journal of Experimental Pathology, EarlyView. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - September 3, 2018 Category: Pathology Authors: Airton Pereira e Silva , Jo ão R. A. Soares , Erika Bertozzi de Aquino Mattos , Claudia Josetti , Isabelle M. Guimarães , Sylvia M. N. Campos , Gerlinde A. P. B. Teixeira Source Type: research

Corrigendum
International Journal of Experimental Pathology,Volume 99, Issue 3, Page 145-145, June 2018. (Source: International Journal of Experimental Pathology)
Source: International Journal of Experimental Pathology - August 22, 2018 Category: Pathology Source Type: research