Factors Influencing a Favorable Outcome for RFA of Huge Benign Thyroid Nodules: Preliminary Results and Short-Term Evaluation
CONCLUSION: RFA was effective at decreasing the volume of huge BTNs with an acceptable complication rate. The BTN characteristics correlated with a better VRR at the 6-month short-term follow-up were predominant solid/spongiform BTNs and those with the first time ablation treatment initial ablation rate. Nevertheless, regarding the higher regrowth rate of these groups of patients who may need to be treated more times, RFA can only be a feasible alternative treatment modality for patients unable or unwilling to undergo operation.PMID:38131035 | PMC:PMC10735726 | DOI:10.1155/2023/9021903 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Chun-Hua Chiu Sheng-Dean Luo Pi-Ling Chiang An-Ni Lin Cheng-Kang Wang Chen-Kai Chou Shun-Yu Chi Meng-Hsiang Chen Wei-Che Lin Source Type: research

Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients
CONCLUSION: Compared with metformin alone in the treatment of PCOS, the differential metabolites of the exenatide combined with metformin group are more extensive. The COM group may act on the hypothalamic-pituitary-gonadal axis (HPO) and its bypass, regulate multiple metabolism pathways such as phospholipids, amino acids, fatty acids, carnitine, bile acids, and glucose directly or indirectly in obese PCOS patients.PMID:38131036 | PMC:PMC10735721 | DOI:10.1155/2023/4288004 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Jingwen Gan Jie Chen Rui-Lin Ma Yan Deng Xue-Song Ding Shi-Yang Zhu Ai-Jun Sun Source Type: research

Calcium Activation of the Androgen Receptor in Prostate Cells
CONCLUSIONS: The results of this study show that calcium activates AR and increases cell growth and that calcium channels are overexpressed in hormone-responsive and hormone-resistant prostate cancer cells. Taken together, the results suggest a novel role of calcium in the castration-resistant phenotype.PMID:38131032 | PMC:PMC10733593 | DOI:10.1155/2023/9907948 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Zeina W Sharawi Sawsan M Khatrawi Qiaochu Wang Hongzhao Zhou Kedra Cyrus Gai Yan Becky Hoxter Bassem R Haddad Mary Beth Martin Source Type: research

GLP1R rs3765467 Polymorphism Is Associated with the Risk of Early Onset Type 2 Diabetes
CONCLUSION: The glucagon-like peptide 1 receptor rs3765467 polymorphism was significantly associated with age at type 2 diabetes diagnosis and thus may be used as a marker to screen and detect individuals at risk of developing early onset type 2 diabetes.PMID:38131033 | PMC:PMC10735718 | DOI:10.1155/2023/8729242 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Yunyun Fang Jingjing Zhang Linlin Ji Chaoyu Zhu Yuanyuan Xiao Qingge Gao Wenjing Song Li Wei Source Type: research

Association between Sleep Duration and Left Ventricular Hypertrophy for Patients with Type 2 Diabetes Mellitus
CONCLUSION: For patients with T2DM, long sleep duration (>8 hours per day), hemoglobin, BUN, and HDL-c were independently associated with LVH. This trial is registered with NCT03811470.PMID:38131034 | PMC:PMC10735725 | DOI:10.1155/2023/5532778 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Lin Mu Chao Li Wenying Zhao Aihua Li Dong Zhao Baoyu Zhang Source Type: research

Factors Influencing a Favorable Outcome for RFA of Huge Benign Thyroid Nodules: Preliminary Results and Short-Term Evaluation
CONCLUSION: RFA was effective at decreasing the volume of huge BTNs with an acceptable complication rate. The BTN characteristics correlated with a better VRR at the 6-month short-term follow-up were predominant solid/spongiform BTNs and those with the first time ablation treatment initial ablation rate. Nevertheless, regarding the higher regrowth rate of these groups of patients who may need to be treated more times, RFA can only be a feasible alternative treatment modality for patients unable or unwilling to undergo operation.PMID:38131035 | PMC:PMC10735726 | DOI:10.1155/2023/9021903 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Chun-Hua Chiu Sheng-Dean Luo Pi-Ling Chiang An-Ni Lin Cheng-Kang Wang Chen-Kai Chou Shun-Yu Chi Meng-Hsiang Chen Wei-Che Lin Source Type: research

Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients
CONCLUSION: Compared with metformin alone in the treatment of PCOS, the differential metabolites of the exenatide combined with metformin group are more extensive. The COM group may act on the hypothalamic-pituitary-gonadal axis (HPO) and its bypass, regulate multiple metabolism pathways such as phospholipids, amino acids, fatty acids, carnitine, bile acids, and glucose directly or indirectly in obese PCOS patients.PMID:38131036 | PMC:PMC10735721 | DOI:10.1155/2023/4288004 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Jingwen Gan Jie Chen Rui-Lin Ma Yan Deng Xue-Song Ding Shi-Yang Zhu Ai-Jun Sun Source Type: research

Calcium Activation of the Androgen Receptor in Prostate Cells
CONCLUSIONS: The results of this study show that calcium activates AR and increases cell growth and that calcium channels are overexpressed in hormone-responsive and hormone-resistant prostate cancer cells. Taken together, the results suggest a novel role of calcium in the castration-resistant phenotype.PMID:38131032 | PMC:PMC10733593 | DOI:10.1155/2023/9907948 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Zeina W Sharawi Sawsan M Khatrawi Qiaochu Wang Hongzhao Zhou Kedra Cyrus Gai Yan Becky Hoxter Bassem R Haddad Mary Beth Martin Source Type: research

GLP1R rs3765467 Polymorphism Is Associated with the Risk of Early Onset Type 2 Diabetes
CONCLUSION: The glucagon-like peptide 1 receptor rs3765467 polymorphism was significantly associated with age at type 2 diabetes diagnosis and thus may be used as a marker to screen and detect individuals at risk of developing early onset type 2 diabetes.PMID:38131033 | PMC:PMC10735718 | DOI:10.1155/2023/8729242 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Yunyun Fang Jingjing Zhang Linlin Ji Chaoyu Zhu Yuanyuan Xiao Qingge Gao Wenjing Song Li Wei Source Type: research

Association between Sleep Duration and Left Ventricular Hypertrophy for Patients with Type 2 Diabetes Mellitus
CONCLUSION: For patients with T2DM, long sleep duration (>8 hours per day), hemoglobin, BUN, and HDL-c were independently associated with LVH. This trial is registered with NCT03811470.PMID:38131034 | PMC:PMC10735725 | DOI:10.1155/2023/5532778 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Lin Mu Chao Li Wenying Zhao Aihua Li Dong Zhao Baoyu Zhang Source Type: research

Factors Influencing a Favorable Outcome for RFA of Huge Benign Thyroid Nodules: Preliminary Results and Short-Term Evaluation
CONCLUSION: RFA was effective at decreasing the volume of huge BTNs with an acceptable complication rate. The BTN characteristics correlated with a better VRR at the 6-month short-term follow-up were predominant solid/spongiform BTNs and those with the first time ablation treatment initial ablation rate. Nevertheless, regarding the higher regrowth rate of these groups of patients who may need to be treated more times, RFA can only be a feasible alternative treatment modality for patients unable or unwilling to undergo operation.PMID:38131035 | PMC:PMC10735726 | DOI:10.1155/2023/9021903 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Chun-Hua Chiu Sheng-Dean Luo Pi-Ling Chiang An-Ni Lin Cheng-Kang Wang Chen-Kai Chou Shun-Yu Chi Meng-Hsiang Chen Wei-Che Lin Source Type: research

Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients
CONCLUSION: Compared with metformin alone in the treatment of PCOS, the differential metabolites of the exenatide combined with metformin group are more extensive. The COM group may act on the hypothalamic-pituitary-gonadal axis (HPO) and its bypass, regulate multiple metabolism pathways such as phospholipids, amino acids, fatty acids, carnitine, bile acids, and glucose directly or indirectly in obese PCOS patients.PMID:38131036 | PMC:PMC10735721 | DOI:10.1155/2023/4288004 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Jingwen Gan Jie Chen Rui-Lin Ma Yan Deng Xue-Song Ding Shi-Yang Zhu Ai-Jun Sun Source Type: research

Elevated Thyroglobulin Antibody Level is Associated with Decreased Anti-M üllerian Hormone in Women of Reproductive Age
CONCLUSION: The AMH of women of reproductive age is affected by HT. Furthermore, women with the lowest AMH level had higher levels of TgAb and a positive rate of TgAb, and high TgAb levels may cause autoimmune damage to the ovaries.PMID:38125684 | PMC:PMC10733051 | DOI:10.1155/2023/1861752 (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - December 21, 2023 Category: Endocrinology Authors: Jazyra Zynat Xinling Wang Li Han Shuqing Xing Guzailinuer Jvlaiti Qingqing Liu Lingling Dong Yanying Guo Source Type: research

Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review
Int J Endocrinol. 2023 Dec 11;2023:1169249. doi: 10.1155/2023/1169249. eCollection 2023.ABSTRACTThe clinical presentation of primary hyperparathyroidism (PHPT) has evolved over the years from a symptomatic disorder to a predominantly asymptomatic condition. Altered vitamin D metabolism seems to play a role in the presentation of PHPT and may exacerbate the severity of disease. The epidemiology of PHPT differs in the developing versus the developed world, where more severe phenotypes occur in regions where vitamin D deficiency is common. Although it has been validated that patients with PHPT should be vitamin D sufficient, ...
Source: International Journal of Endocrinology - December 20, 2023 Category: Endocrinology Authors: Niharika Yedla Hyon Kim Anupa Sharma Xiangbing Wang Source Type: research