International Journal of Developmental Neuroscience This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Aggravation of cognitive impairments in the valproic acid-induced animal model of autism in BALB/c mice infected with Toxoplasma gondii
Int J Dev Neurosci. 2023 Nov 14. doi: 10.1002/jdn.10308. Online ahead of print.ABSTRACTPURPOSE: Toxoplasmosis is a disease caused by infection with a type of coccidial protozoan parasite called Toxoplasma gondii. The relationship between toxoplasmosis and cognitive disorders in neurodegenerative diseases has been proven. There is also evidence that children born to Toxoplasma-infected mothers are more likely to develop autism.METHODS: In the present study, Toxoplasma-infected pregnant BALB/c mice were given valproic acid to induce autism in their male offspring, and their social behaviors, learning, and memory were examine...
Source: International Journal of Developmental Neuroscience - November 14, 2023 Category: Neuroscience Authors: Saeed Sheikhshoaee Farahnaz Taheri Khadijeh Esmaeilpour Nima Firouzeh Saeid Reza Nourollahi Fard Source Type: research

Sex-specific dendritic morphology of hippocampal pyramidal neurons in the adolescent and young adult rats
Int J Dev Neurosci. 2023 Nov 7. doi: 10.1002/jdn.10307. Online ahead of print.ABSTRACTCA1 and CA3 pyramidal neurons are the major sources of hippocampal efferents. The structural features of these neurons are presumed to be involved in various normal/abnormal cognitive and emotional outcomes by influencing the pattern of synaptic inputs and neuronal signal processing. Although many studies have described hippocampal structure differences between males and females, these reports mainly focused on gross anatomical features in adult or aged models, and such distinctions on neuronal morphology and dendritic spine density durin...
Source: International Journal of Developmental Neuroscience - November 7, 2023 Category: Neuroscience Authors: Parisa Yarmohammadi-Samani Jafar Vatanparast Source Type: research

Complex genotypes in family with metachromatic leukodystrophy: Effect of trans and cis mutations distribution on the phenotype variability
In conclusion, we identified a complex genotype of ARSA variants within two MLD siblings with a variable severity due to a de novo variant present in one of them. Our results allowed the establishment of an adult MLD diagnosis and highlighted the importance of an assessment of the trans/cis distribution in the cases of complex genotypes.PMID:37848385 | DOI:10.1002/jdn.10306 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - October 17, 2023 Category: Neuroscience Authors: Abir Ben Issa Fatma Kamoun Wafa Bouchaala Chahnez Charfi Triki Faiza Fakhfakh Source Type: research