Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Infantile epileptic spasm syndrome as a new NR2F1 gene phenotype
CONCLUSIONS: Our findings indicate that new missense NR2F1 pathogenetic variants may lead to IESS with abnormal visual evoked potentials. Thus, clinicians should be aware of the Bosch-Boonstra-Schaaf optic atrophy syndrome and regular monitoring of the fundus, and the optic nerve is necessary during follow-up.PMID:38010976 | DOI:10.1002/jdn.10309 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - November 27, 2023 Category: Neuroscience Authors: Yan Liang Lin Wan Xinting Liu Jing Zhang Gang Zhu Guang Yang Source Type: research

Aggravation of cognitive impairments in the valproic acid-induced animal model of autism in BALB/c mice infected with Toxoplasma gondii
Int J Dev Neurosci. 2023 Nov 14. doi: 10.1002/jdn.10308. Online ahead of print.ABSTRACTPURPOSE: Toxoplasmosis is a disease caused by infection with a type of coccidial protozoan parasite called Toxoplasma gondii. The relationship between toxoplasmosis and cognitive disorders in neurodegenerative diseases has been proven. There is also evidence that children born to Toxoplasma-infected mothers are more likely to develop autism.METHODS: In the present study, Toxoplasma-infected pregnant BALB/c mice were given valproic acid to induce autism in their male offspring, and their social behaviors, learning, and memory were examine...
Source: International Journal of Developmental Neuroscience - November 14, 2023 Category: Neuroscience Authors: Saeed Sheikhshoaee Farahnaz Taheri Khadijeh Esmaeilpour Nima Firouzeh Saeid Reza Nourollahi Fard Source Type: research

Aggravation of cognitive impairments in the valproic acid-induced animal model of autism in BALB/c mice infected with Toxoplasma gondii
Int J Dev Neurosci. 2023 Nov 14. doi: 10.1002/jdn.10308. Online ahead of print.ABSTRACTPURPOSE: Toxoplasmosis is a disease caused by infection with a type of coccidial protozoan parasite called Toxoplasma gondii. The relationship between toxoplasmosis and cognitive disorders in neurodegenerative diseases has been proven. There is also evidence that children born to Toxoplasma-infected mothers are more likely to develop autism.METHODS: In the present study, Toxoplasma-infected pregnant BALB/c mice were given valproic acid to induce autism in their male offspring, and their social behaviors, learning, and memory were examine...
Source: International Journal of Developmental Neuroscience - November 14, 2023 Category: Neuroscience Authors: Saeed Sheikhshoaee Farahnaz Taheri Khadijeh Esmaeilpour Nima Firouzeh Saeid Reza Nourollahi Fard Source Type: research

Aggravation of cognitive impairments in the valproic acid-induced animal model of autism in BALB/c mice infected with Toxoplasma gondii
Int J Dev Neurosci. 2023 Nov 14. doi: 10.1002/jdn.10308. Online ahead of print.ABSTRACTPURPOSE: Toxoplasmosis is a disease caused by infection with a type of coccidial protozoan parasite called Toxoplasma gondii. The relationship between toxoplasmosis and cognitive disorders in neurodegenerative diseases has been proven. There is also evidence that children born to Toxoplasma-infected mothers are more likely to develop autism.METHODS: In the present study, Toxoplasma-infected pregnant BALB/c mice were given valproic acid to induce autism in their male offspring, and their social behaviors, learning, and memory were examine...
Source: International Journal of Developmental Neuroscience - November 14, 2023 Category: Neuroscience Authors: Saeed Sheikhshoaee Farahnaz Taheri Khadijeh Esmaeilpour Nima Firouzeh Saeid Reza Nourollahi Fard Source Type: research

Aggravation of cognitive impairments in the valproic acid-induced animal model of autism in BALB/c mice infected with Toxoplasma gondii
Int J Dev Neurosci. 2023 Nov 14. doi: 10.1002/jdn.10308. Online ahead of print.ABSTRACTPURPOSE: Toxoplasmosis is a disease caused by infection with a type of coccidial protozoan parasite called Toxoplasma gondii. The relationship between toxoplasmosis and cognitive disorders in neurodegenerative diseases has been proven. There is also evidence that children born to Toxoplasma-infected mothers are more likely to develop autism.METHODS: In the present study, Toxoplasma-infected pregnant BALB/c mice were given valproic acid to induce autism in their male offspring, and their social behaviors, learning, and memory were examine...
Source: International Journal of Developmental Neuroscience - November 14, 2023 Category: Neuroscience Authors: Saeed Sheikhshoaee Farahnaz Taheri Khadijeh Esmaeilpour Nima Firouzeh Saeid Reza Nourollahi Fard Source Type: research

Aggravation of cognitive impairments in the valproic acid-induced animal model of autism in BALB/c mice infected with Toxoplasma gondii
Int J Dev Neurosci. 2023 Nov 14. doi: 10.1002/jdn.10308. Online ahead of print.ABSTRACTPURPOSE: Toxoplasmosis is a disease caused by infection with a type of coccidial protozoan parasite called Toxoplasma gondii. The relationship between toxoplasmosis and cognitive disorders in neurodegenerative diseases has been proven. There is also evidence that children born to Toxoplasma-infected mothers are more likely to develop autism.METHODS: In the present study, Toxoplasma-infected pregnant BALB/c mice were given valproic acid to induce autism in their male offspring, and their social behaviors, learning, and memory were examine...
Source: International Journal of Developmental Neuroscience - November 14, 2023 Category: Neuroscience Authors: Saeed Sheikhshoaee Farahnaz Taheri Khadijeh Esmaeilpour Nima Firouzeh Saeid Reza Nourollahi Fard Source Type: research