Haloperidol alters neurotrophic factors and epigenetic parameters in an animal model of schizophrenia induced by ketamine
This study aimed to evaluate Haloperidol's (Hal) effects on the behavioral, neurotrophic factors, and epigenetic parameters in an animal model of schizophrenia (SCZ) induced by ketamine (Ket). Injections of Ket or saline were administered intraperitoneal (once a day) between the 1st and 14th days of the experiment. Water or Hal was administered via gavage between the 8th and 14th experimental days. Thirty minutes after the last injection, the animals were subjected to behavioral analysis. The activity of DNA methyltransferase (DNMT), histone deacetylase (HDAC), and histone acetyltransferase and levels of brain-derived neur...
Source: International Journal of Developmental Neuroscience - August 27, 2023 Category: Neuroscience Authors: Samira S Valvassori Richard T da Rosa Gustavo C Dal-Pont Roger B Varela Gustavo A Mastella Thiani Daminelli Gabriel R Fries Jo ão Quevedo Alexandra I Zugno Source Type: research

Brain structural changes in alternating hemiplegia of childhood using single-case voxel-based morphometry analysis
CONCLUSION: With single-case VBM analysis, we could show the association between region-specific changes in brain volume and the severity of various clinical symptoms even in a small sample of subjects.PMID:37604479 | DOI:10.1002/jdn.10295 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 21, 2023 Category: Neuroscience Authors: Elly Arizono Noriko Sato Yoko Shigemoto Yukio Kimura Emiko Chiba Hiroyuki Maki Hiroshi Matsuda Eri Takeshita Yuko Shimizu-Motohashi Masayuki Sasaki Kazuhiro Saito Source Type: research

Brain structural changes in alternating hemiplegia of childhood using single-case voxel-based morphometry analysis
CONCLUSION: With single-case VBM analysis, we could show the association between region-specific changes in brain volume and the severity of various clinical symptoms even in a small sample of subjects.PMID:37604479 | DOI:10.1002/jdn.10295 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 21, 2023 Category: Neuroscience Authors: Elly Arizono Noriko Sato Yoko Shigemoto Yukio Kimura Emiko Chiba Hiroyuki Maki Hiroshi Matsuda Eri Takeshita Yuko Shimizu-Motohashi Masayuki Sasaki Kazuhiro Saito Source Type: research

Brain structural changes in alternating hemiplegia of childhood using single-case voxel-based morphometry analysis
CONCLUSION: With single-case VBM analysis, we could show the association between region-specific changes in brain volume and the severity of various clinical symptoms even in a small sample of subjects.PMID:37604479 | DOI:10.1002/jdn.10295 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 21, 2023 Category: Neuroscience Authors: Elly Arizono Noriko Sato Yoko Shigemoto Yukio Kimura Emiko Chiba Hiroyuki Maki Hiroshi Matsuda Eri Takeshita Yuko Shimizu-Motohashi Masayuki Sasaki Kazuhiro Saito Source Type: research

Brain structural changes in alternating hemiplegia of childhood using single-case voxel-based morphometry analysis
CONCLUSION: With single-case VBM analysis, we could show the association between region-specific changes in brain volume and the severity of various clinical symptoms even in a small sample of subjects.PMID:37604479 | DOI:10.1002/jdn.10295 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 21, 2023 Category: Neuroscience Authors: Elly Arizono Noriko Sato Yoko Shigemoto Yukio Kimura Emiko Chiba Hiroyuki Maki Hiroshi Matsuda Eri Takeshita Yuko Shimizu-Motohashi Masayuki Sasaki Kazuhiro Saito Source Type: research

Brain structural changes in alternating hemiplegia of childhood using single-case voxel-based morphometry analysis
CONCLUSION: With single-case VBM analysis, we could show the association between region-specific changes in brain volume and the severity of various clinical symptoms even in a small sample of subjects.PMID:37604479 | DOI:10.1002/jdn.10295 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 21, 2023 Category: Neuroscience Authors: Elly Arizono Noriko Sato Yoko Shigemoto Yukio Kimura Emiko Chiba Hiroyuki Maki Hiroshi Matsuda Eri Takeshita Yuko Shimizu-Motohashi Masayuki Sasaki Kazuhiro Saito Source Type: research

Stunting and wasting in neurological Wilson disease: Role of copper, zinc, and insulin-like growth factor-I
CONCLUSIONS: Stunting and/or wasting occurs in 15.4% of children with neurologic WD and is associated with reduced serum IGF-I, Zn, and calcium concentration. Adjunctive Zn and calcium treatment may help in achieving normal growth.PMID:37580872 | DOI:10.1002/jdn.10293 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Vijay Kumar Jayantee Kalita Usha Kant Misra Vasudev Parashar Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research

Stunting and wasting in neurological Wilson disease: Role of copper, zinc, and insulin-like growth factor-I
CONCLUSIONS: Stunting and/or wasting occurs in 15.4% of children with neurologic WD and is associated with reduced serum IGF-I, Zn, and calcium concentration. Adjunctive Zn and calcium treatment may help in achieving normal growth.PMID:37580872 | DOI:10.1002/jdn.10293 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Vijay Kumar Jayantee Kalita Usha Kant Misra Vasudev Parashar Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research

Stunting and wasting in neurological Wilson disease: Role of copper, zinc, and insulin-like growth factor-I
CONCLUSIONS: Stunting and/or wasting occurs in 15.4% of children with neurologic WD and is associated with reduced serum IGF-I, Zn, and calcium concentration. Adjunctive Zn and calcium treatment may help in achieving normal growth.PMID:37580872 | DOI:10.1002/jdn.10293 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Vijay Kumar Jayantee Kalita Usha Kant Misra Vasudev Parashar Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research

Stunting and wasting in neurological Wilson disease: Role of copper, zinc, and insulin-like growth factor-I
CONCLUSIONS: Stunting and/or wasting occurs in 15.4% of children with neurologic WD and is associated with reduced serum IGF-I, Zn, and calcium concentration. Adjunctive Zn and calcium treatment may help in achieving normal growth.PMID:37580872 | DOI:10.1002/jdn.10293 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Vijay Kumar Jayantee Kalita Usha Kant Misra Vasudev Parashar Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research

Stunting and wasting in neurological Wilson disease: Role of copper, zinc, and insulin-like growth factor-I
CONCLUSIONS: Stunting and/or wasting occurs in 15.4% of children with neurologic WD and is associated with reduced serum IGF-I, Zn, and calcium concentration. Adjunctive Zn and calcium treatment may help in achieving normal growth.PMID:37580872 | DOI:10.1002/jdn.10293 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Vijay Kumar Jayantee Kalita Usha Kant Misra Vasudev Parashar Source Type: research