Random blood glucose screening at a public health station encouraged high risk subjects to make lifestyle changes
ConclusionThe station was effective in promoting additional screening among high‐risk age groups and encourages subjects to make lifestyle changes. Operating the screening station is simple and effective; therefore it may serve as a complementary step in promoting community healthcare. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - July 1, 2017 Category: Internal Medicine Authors: Karin Elman, Julio Wainstein, Mona Boaz, Daniela Jacubovitz, Yosefa Bar ‐Dayan Tags: ORIGINAL PAPER Source Type: research

Anti ‐PCSK9 antibodies for hypercholesterolaemia: Overview of clinical data and implications for primary care
ConclusionsAnti‐PCSK9 antibodies effectively lower LDL‐C levels in a broad patient population. While awaiting comprehensive data from CV outcome trials, these agents should be considered in very high risk patients, such as those in secondary prevention and those with familial hypercholesterolaemia who are already receiving maximally tolerated LLTs, have not achieved their LDL‐C goal and require substantial reductions in LDL‐C. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - July 1, 2017 Category: Internal Medicine Authors: Olivier S. Descamps, Uwe Fraass, Ricardo Dent, Winfried M ärz, Ioanna Gouni‐Berthold Tags: REVIEW ARTICLE Source Type: research

Potentially inappropriate use of furosemide in a very elderly population: An observational study
ConclusionsIn this large study, long‐course furosemide was prescribed in a quarter of ambulatory patients. Half of those taking furosemide suffered from severe heart failure. Age was associated with a linear increase in furosemide use and a decrease in recommended heart failure therapeutic prescriptions. A large part of these prescriptions do not seem to be in accordance with recommendations. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 15, 2017 Category: Internal Medicine Authors: Carla Rodriguez ‐Cillero, Didier Menu, Philippe d'Athis, Sophie Perrin, Mélanie Dipanda, Sanaa Asgassou, Hélène Guepet, Emmanuel Mazen, Patrick Manckoundia, Alain Putot Tags: ORIGINAL PAPER Source Type: research

Mugs of the bugs: The most wanted ones
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 15, 2017 Category: Internal Medicine Authors: Richard A. Stein Tags: PERSPECTIVE Source Type: research

Truncal ataxia or disequilibrium is an unrecognised cause of orthostatic intolerance in patients with myalgic encephalomyelitis
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 14, 2017 Category: Internal Medicine Authors: Kunihisa Miwa, Yukichi Inoue Tags: LETTER Source Type: research

Make the DRE great again
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 14, 2017 Category: Internal Medicine Authors: Matt T. Rosenberg Tags: EDITORIAL Source Type: research

The scourge of uromycitisis and fake journals
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 14, 2017 Category: Internal Medicine Authors: Leslie Citrome Tags: EDITORIAL Source Type: research

Issue Information
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 14, 2017 Category: Internal Medicine Tags: ISSUE INFORMATION Source Type: research

Cover Image
The cover image, by Stephen M. Zappala et al., is based on the Original Paper The 4Kscore blood test accurately identifies men with aggressive prostate cancer prior to prostate biopsy with or without DRE information, DOI 10.1111/ijcp.12943. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 14, 2017 Category: Internal Medicine Authors: Stephen M. Zappala, Yan Dong, Vincent Linder, Michael Reeve, Daniel D. Sjoberg, Vinita Mathur, Richard Roberts, David Okrongly, Jay Newmark, Garnnum Sant, Mitchell Steiner Tags: COVER IMAGE Source Type: research

What is safety?: Miracles, benefit ‐risk assessments, and the “right to try”
Conclusions, which weigh and consider effectiveness and safety together. Yet fundamental differences in understanding the “safety” of medicinal products continue to exist between experts in biomedicine, politicians, and healthcare activists. Examining differences in the understanding of “safety” between experts and non‐experts also may help explain the source for flawed logic about the safety of investigational products in Right To Try narratives. No drug product is 100% safe. Continuing to weigh benefits and risks together is an important intellectual practice necessary to safeguard human health worldwide, and t...
Source: International Journal of Clinical Practice - June 8, 2017 Category: Internal Medicine Authors: Lisa M. DeTora Tags: PERSPECTIVE Source Type: research

Computer vision syndrome —A common cause of unexplained visual symptoms in the modern era
Summary ObjectivesThe aim of this study was to assess the evidence and available literature on the clinical, pathogenetic, prognostic and therapeutic aspects of Computer vision syndrome. MethodsInformation was collected from Medline, Embase & National Library of Medicine over the last 30 years up to March 2016. The bibliographies of relevant articles were searched for additional references. FindingsPatients with Computer vision syndrome present to a variety of different specialists, including General Practitioners, Neurologists, Stroke physicians and Ophthalmologists. While the condition is common, there is a poor awa...
Source: International Journal of Clinical Practice - June 8, 2017 Category: Internal Medicine Authors: Sunil Munshi, Ashley Varghese, Sushma Dhar ‐Munshi Tags: REVIEW ARTICLE Source Type: research

Initiating insulin: How to help people with type 2 diabetes start and continue insulin successfully
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 1, 2017 Category: Internal Medicine Authors: William H. Polonsky, Joyce Arsenault, Lawrence Fisher, Pamela Kushner, Eden M. Miller, Teresa L. Pearson, Mariusz Tracz, Stewart Harris, Norbert Hermanns, Bernd ‐M. Scholz, Robyn K. Pollom, Magaly Perez‐Nieves, Roy Daniel Pollom, Irene Hadjiyianni Tags: PERSPECTIVE Source Type: research

Switching to a rilpivirine/emtricitabine/tenofovir single ‐tablet regimen in RNA‐suppressed patients infected with human immunodeficiency virus 1: Effectiveness, safety and costs at 96 weeks
ConclusionsIn virologically suppressed patients, the switch to a RPV/FTC/TDF regimen was associated with a mild but maintained improvement in lipid parameters and a significant reduction in costs. However, the relatively high rates of virological failure and treatment discontinuation because of adverse events make this combination a less favourable choice over other regimens currently available. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 1, 2017 Category: Internal Medicine Authors: Paula Arrabal ‐Durán, Carmen G Rodríguez‐González, Esther Chamorro‐de‐Vega, Paloma Gijón‐Vidaurreta, Ana Herranz‐Alonso, María Sanjurjo‐Sáez Tags: Original Paper Source Type: research

Assessing the quality of primary care referrals to surgery of patients with diabetes in the East of England: A multi ‐centre cross‐sectional cohort study
ConclusionThis study has shown that the quality of referral letters to surgical specialties for patients with DM in the East of England remain inadequate. There is a clear need for improving the quality of clinical data contained within referral letters from primary care. In addition, we have shown that the rate of referral for surgery for people with diabetes is almost 50% higher than the background population with diabetes. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - June 1, 2017 Category: Internal Medicine Authors: Dimitri J. Pournaras, Evangelos S. Photi, Nicholas Barnett, Christopher P. Challand, Nikolaos A. Chatzizacharias, Nokwanda P. Dlamini, Triantafyllos Doulias, Aoibhinn Foley, James Hernon, Bhaskar Kumar, Jack Martin, Ian Nunney, Ioanna Panagiotopoulou, Nee Tags: ORIGINAL PAPER Source Type: research

Direct medical costs of severe hypoglycaemic events in patients with type 2 diabetes in England: A retrospective database study
ConclusionRates of severe hypoglycaemic events varied substantially between T2DM regimens. In this study of patients treated in clinical practice in England, sulfonylurea‐ and insulin‐based regimens were associated with the highest event rates and costs associated with hospitalisation for severe hypoglycaemic events; hospitalisation for severe hypoglycaemic events was not observed with dipeptidyl peptidase‐4 inhibitor monotherapy or with metformin. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - May 23, 2017 Category: Internal Medicine Authors: Tim Holbrook, Yuexin Tang, Romita Das, R. Ravi Shankar, Kaan Tunceli, Jean Williams, Larry Radican, Sarah E. Holden, Chris Ll. Morgan, James Piercy, Craig J. Currie Tags: ORIGINAL PAPER Source Type: research