The effectiveness of ibandronate in reducing the risk of nonvertebral fractures in women with osteoporosis: systematic review and meta-analysis of observational studies
ConclusionResults suggest that once-monthly 150  mg oral ibandronate may be as effective as other oral bisphosphonates in reducing the risk of nonvertebral fractures. However, uncertainty associated to the small number of included studies, which are characterized by heterogeneous demographics and methodologies, precluded definitive conclusions. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 19, 2023 Category: Drugs & Pharmacology Source Type: research

What do emergency department pharmacist practitioners know and understand about patient safeguarding? A qualitative study
ConclusionWhile Emergency Department Pharmacist Practitioners interviewed were aware of  the safeguarding process, there were some misconceptions as to the roles of different healthcare workers in this process. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 19, 2023 Category: Drugs & Pharmacology Source Type: research

Real-world data of atezolizumab in patients with previously treated locally advanced or metastatic urothelial bladder cancer
ConclusionIn a real-world population with previously treated mUBC, atezolizumab seems to provide clinically relevant benefit, which is even higher for patients with ECOG 0 –1 and without liver metastases, with an acceptable safety profile. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 19, 2023 Category: Drugs & Pharmacology Source Type: research

The effectiveness of ibandronate in reducing the risk of nonvertebral fractures in women with osteoporosis: systematic review and meta-analysis of observational studies
ConclusionResults suggest that once-monthly 150  mg oral ibandronate may be as effective as other oral bisphosphonates in reducing the risk of nonvertebral fractures. However, uncertainty associated to the small number of included studies, which are characterized by heterogeneous demographics and methodologies, precluded definitive conclusions. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 19, 2023 Category: Drugs & Pharmacology Source Type: research

What do emergency department pharmacist practitioners know and understand about patient safeguarding? A qualitative study
ConclusionWhile Emergency Department Pharmacist Practitioners interviewed were aware of  the safeguarding process, there were some misconceptions as to the roles of different healthcare workers in this process. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 19, 2023 Category: Drugs & Pharmacology Source Type: research

Assessing safety concerns of interstitial lung disease associated with antibody-drug conjugates: a real-world pharmacovigilance evaluation of the FDA adverse event reporting system
ConclusionThis real-world study highlights high safety signals of interstitial lung disease associated with antibody-drug conjugates. Clinicians should be aware of these safety concerns and risk factors and implement early identification measures for their patients. Future research should prioritize comprehensively exploring the relationship between antibody-drug conjugates and lung diseases. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 15, 2023 Category: Drugs & Pharmacology Source Type: research

Bibliometric analysis of research trends and active research areas in chimeric antigen receptor T cell therapy for hematologic malignancies
ConclusionThis study provided a comprehensive analysis of publications on CAR T-cell therapy for hematologic malignancies from 2000 to 2023. The findings provide current trends and potential hotspots in CAR T-cell therapy for hematologic malignancies and contribute valuable direction for future studies in this field. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 12, 2023 Category: Drugs & Pharmacology Source Type: research

Valproic acid for agitation in the intensive care unit: an observational study of psychiatric consults
ConclusionAlthough VPA used as adjuvant treatment was associated with a decrease in agitation, its effect when compared to SOC did not yield significant results. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 10, 2023 Category: Drugs & Pharmacology Source Type: research

Embedding cultural competency and cultural humility in undergraduate pharmacist initial education and training: a qualitative exploration of pharmacy student perspectives
ConclusionThese findings offer actionable recommendations to align with the updated Initial Education and Training standards from the United Kingdom (UK) pharmacy regulator, the General Pharmaceutical Council; specifically,how andwhen cultural competency teaching should be embedded within the undergraduate pharmacy curriculum. Future research should further explore teaching content, learning environments, and methods of assessing cultural competency. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 8, 2023 Category: Drugs & Pharmacology Source Type: research

The RESPECT-tool as a facilitator for person-centered medication reviews for nursing home residents: tool development and pilot study
ConclusionA person-centered medication review facilitated by the RESPECT-tool holds a promising approach to medication optimization in nursing homes. Further research should assess impact on relevant outcomes like goal attainment, appropriateness of prescribing and quality of life. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - December 1, 2023 Category: Drugs & Pharmacology Source Type: research