Effect of duloxetine on pain and opioid consumption after total knee and hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials
Conclusion Perioperative duloxetine significantly decreased postoperative pain and opioid consumption with good safety profiles. Further high quality designed and well-controlled randomized trials are warranted. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 9, 2023 Category: Drugs & Pharmacology Source Type: research

Author Correction to: The effectiveness and safety of bevacizumab versus cetuximab in the treatment of colorectal cancer: a systematic review and meta ‑analysis
(Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 9, 2023 Category: Drugs & Pharmacology Source Type: research

Hepatitis B reactivation in patients with multiple myeloma treated with anti-CD38 monoclonal antibody-based therapies: a pharmacovigilance analysis
ConclusionOverall, our analysis demonstrates a significant reporting signal for HBV reactivation with daratumumab and isatuximab. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 8, 2023 Category: Drugs & Pharmacology Source Type: research

Antimicrobial utilization and resistance in Pseudomonas aeruginosa using segmented regression analysis: a comparative study between Serbia and eight European Countries
ConclusionThe use of piperacillin/tazobactam, ceftazidime and fluoroquinolones should be carefully monitored in clinical practice due to increasedPseudomonas aeruginosa resistance. The level of utilization and AMR inPseudomonas aeruginosa is still high in Serbia compared to other European countries. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 7, 2023 Category: Drugs & Pharmacology Source Type: research

Under-reporting of gastrointestinal bleeding associated with anticoagulant use using the UK Yellow Card Scheme
ConclusionUtilisation of the Yellow Card System for reporting potential ADR is poor, leading to under-reporting of ADRs. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

An assessment of the reporting of tapering methods in antidepressant discontinuation trials using the TIDieR checklist
ConclusionThe findings highlight a lack of detailed reporting of antidepressant tapering methods in published trials to date. This needs to be addressed as poor reporting could hinder replication and adaptation of existing interventions, as well as the potential for successful translation of effective tapering interventions into clinical practice. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

Evaluating the potential outcomes of pharmacist-led activities in the Australian general practice setting: a prospective observational study
ConclusionMost pharmacist-led clinical activities in general practice had the potential for a positive impact on patients and reduction in healthcare costs, supporting the expansion of this model in Australia. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

Community pharmacies as a place for informal carer support in mental health and wellbeing
AbstractThere are 5.3 million informal carers in the United Kingdom who take on caring responsibilities for family and friends. Informal carers can be forgotten patients within health and care services, yet because of carer burden, they are at risk of deterioration in health and wellbeing. There are higher levels of anxiety, depression, burnout and low self-esteem amongst carers but, to our knowledge work to date has mainly focused on supporting carers to provide better care for their family member, and less on carers ’ health and wellbeing. There is increasing interest in social prescribing as a method of linking patien...
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

Under-reporting of gastrointestinal bleeding associated with anticoagulant use using the UK Yellow Card Scheme
ConclusionUtilisation of the Yellow Card System for reporting potential ADR is poor, leading to under-reporting of ADRs. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

An assessment of the reporting of tapering methods in antidepressant discontinuation trials using the TIDieR checklist
ConclusionThe findings highlight a lack of detailed reporting of antidepressant tapering methods in published trials to date. This needs to be addressed as poor reporting could hinder replication and adaptation of existing interventions, as well as the potential for successful translation of effective tapering interventions into clinical practice. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

Evaluating the potential outcomes of pharmacist-led activities in the Australian general practice setting: a prospective observational study
ConclusionMost pharmacist-led clinical activities in general practice had the potential for a positive impact on patients and reduction in healthcare costs, supporting the expansion of this model in Australia. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

Community pharmacies as a place for informal carer support in mental health and wellbeing
AbstractThere are 5.3 million informal carers in the United Kingdom who take on caring responsibilities for family and friends. Informal carers can be forgotten patients within health and care services, yet because of carer burden, they are at risk of deterioration in health and wellbeing. There are higher levels of anxiety, depression, burnout and low self-esteem amongst carers but, to our knowledge work to date has mainly focused on supporting carers to provide better care for their family member, and less on carers ’ health and wellbeing. There is increasing interest in social prescribing as a method of linking patien...
Source: International Journal of Clinical Pharmacy - June 3, 2023 Category: Drugs & Pharmacology Source Type: research

Practices, beliefs, and attitudes of clinicians in prescribing direct oral anticoagulants for obese adults with atrial fibrillation: a qualitative study
ConclusionThis study highlights the complexity of decision-making for clinicians, due to the limited availability, reliability and awareness of evidence, the intrinsic complexity of the obese cohort and limited guidance from clinical guidelines. This highlights the urgent need for contemporary research to improve the quality of evidence to guide informed shared decision-making. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - May 30, 2023 Category: Drugs & Pharmacology Source Type: research