How to manage the dose of drugs in cancer patients with acute kidney injury, practical recommendations
AbstractAcute kidney injury (AKI) and chronic kidney disease (CKD) are common in cancer patients. AKI is a brutal and reversible condition which makes it hard to manage from a pharmacological perspective when patients are receiving anticancer regimens and other supportive care drugs, such as anticoagulants, analgesics and other drugs. In contrast to CKD, which is a slow progressive disease, there is no clear guidance on how to manage and/or modify the dosage of drugs during AKI. Indeed, the slow progression of CKD allows physicians to monitor the renal function by using the glomerular filtration rate. Consequently, publica...
Source: International Journal of Clinical Pharmacy - October 26, 2023 Category: Drugs & Pharmacology Source Type: research

Understanding general practitioners ’ prescribing choices to patients with chronic low back pain: a discrete choice experiment
ConclusionGPs prefer prescribing NSAIDs over opioids for a patient with chronic low back pain regardless of patient factors of comorbidities or the presence of leg pain (i.e. sciatica). (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 26, 2023 Category: Drugs & Pharmacology Source Type: research

How to manage the dose of drugs in cancer patients with acute kidney injury, practical recommendations
AbstractAcute kidney injury (AKI) and chronic kidney disease (CKD) are common in cancer patients. AKI is a brutal and reversible condition which makes it hard to manage from a pharmacological perspective when patients are receiving anticancer regimens and other supportive care drugs, such as anticoagulants, analgesics and other drugs. In contrast to CKD, which is a slow progressive disease, there is no clear guidance on how to manage and/or modify the dosage of drugs during AKI. Indeed, the slow progression of CKD allows physicians to monitor the renal function by using the glomerular filtration rate. Consequently, publica...
Source: International Journal of Clinical Pharmacy - October 26, 2023 Category: Drugs & Pharmacology Source Type: research

Comparing patient reported and medical record data of adverse drug reactions to anti-seizure drugs
ConclusionConfirmation of patient-reported ADRs with either laboratory data or medical records was uncommon. Recording patient-reported ADRs in patients ’ medical history and monitoring laboratory tests related to patient-reported symptoms should be promoted to increase the safety of ASD treatment. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 16, 2023 Category: Drugs & Pharmacology Source Type: research

A novel machine learning model to predict high on-treatment platelet reactivity on clopidogrel in Asian  patients after percutaneous coronary intervention
ConclusionA ML-based approach, such as XGBoost, showed optimum performance and might help predict HTPR on clopidogrel after PCI and guide clinical decision-making. Further validated studies will strengthen this finding. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 10, 2023 Category: Drugs & Pharmacology Source Type: research

Pharmacy student attitudes to mental illness and the provision of mental health care: a repeated cross-sectional survey
ConclusionIrish pharmacy students have generally positive attitudes towards people with severe mental illness and provision of medicines optimisation services. There is an opportunity to improve pharmacy graduates perceived competence and confidence to provide mental health services. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 7, 2023 Category: Drugs & Pharmacology Source Type: research

Overview of this issue: “clinical pharmacy impacting mental health delivery and outcomes”
(Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 6, 2023 Category: Drugs & Pharmacology Source Type: research

Opinions and experiences on the provision of care to people with mental illnesses: a qualitative study with Doctor of Pharmacy graduates after a rotation in psychiatry
ConclusionFor the most part, the APPE in psychiatry was viewed as a positive opportunity for enhancing the PharmD graduates ’ insight, knowledge, and skills for pharmaceutical care provision to people with mental illnesses. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 5, 2023 Category: Drugs & Pharmacology Source Type: research

Perinatal depression screening in community pharmacy: Exploring pharmacists ’ roles, training and resource needs using content analysis
ConclusionWhile some pharmacists were accepting of a role in PND screening due to pharmacists ’ accessibility and positive relationships with consumers, others had concerns regarding whether PND screening was within pharmacists’ scope of practice. Further training and resources are needed to facilitate pharmacists’ roles in PND screening, referral and care. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 4, 2023 Category: Drugs & Pharmacology Source Type: research