Clinical and research implications of uricase knockout and renal injury
Int J Clin Pharmacol Ther. 2024 Mar 3. doi: 10.5414/CPP62149. Online ahead of print.NO ABSTRACTPMID:38431831 | DOI:10.5414/CPP62149 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 3, 2024 Category: Drugs & Pharmacology Authors: ShaoJun Zheng Source Type: research

Evaluation of the risk factors for the failure of a single prophylactic dose of anticholinergic drugs for irinotecan-induced cholinergic symptoms
CONCLUSION: We determined that colorectal cancer, female sex, and prophylactic use of scopolamine butyl bromide were risk factors associated with the failure of a single prophylactic dose of anticholinergic drugs, and that multiple prophylactic doses for wearing-off can be a promising method.PMID:38431832 | DOI:10.5414/CP204531 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 3, 2024 Category: Drugs & Pharmacology Authors: Takuya Watanabe Yoshitaka Saito Yoh Takekuma Yasushi Shimizu Ichiro Kinoshita Yoshito Komatsu Mitsuru Sugawara Source Type: research

Low albumin combined with low-molecular-weight heparin as risk factors for liver injury using azvudine: Evidence from an analysis of COVID-19 patients in a national prospective pharmacovigilance database
CONCLUSION: This study represents the first investigation of azvudine-induced liver injury and high-risk patients using the CHPS. The findings provide valuable insights to promote the safety of anti-COVID-19 drugs, serving as an important reference for future drug safety measures.PMID:38431833 | DOI:10.5414/CP204544 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 3, 2024 Category: Drugs & Pharmacology Authors: Hong Lu Ying Zeng Qun-Zhi Shi Lin Liu Yong-Qing Gong Sen Li Pan Yan Source Type: research

Clinical implications and future prospects of levonorgestrel and piroxicam as a combined emergency contraceptive regimen
Int J Clin Pharmacol Ther. 2024 Feb 8. doi: 10.5414/CP204537. Online ahead of print.NO ABSTRACTPMID:38329915 | DOI:10.5414/CP204537 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Jiawei Ke Jingrui Cai Xiaolin Liu Liwen Chen Tianhui Liu Zhipeng Ruan Chengfei Zhao Source Type: research

Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach
CONCLUSION: AUC calculated using the Bayesian software allows for calculation with samples at a non-steady state, can integrate covariates, and is interconvertible with that estimated using an equation-based calculator, which is simpler and relies on fewer assumptions. Therefore, either method can be used, considering each method's strengths and limitations.PMID:38329916 | DOI:10.5414/CP204508 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Eojin Lee Uijeong Yu Ji In Park Sang-In Park Source Type: research

Clinical implications and future prospects of levonorgestrel and piroxicam as a combined emergency contraceptive regimen
Int J Clin Pharmacol Ther. 2024 Feb 8. doi: 10.5414/CP204537. Online ahead of print.NO ABSTRACTPMID:38329915 | DOI:10.5414/CP204537 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Jiawei Ke Jingrui Cai Xiaolin Liu Liwen Chen Tianhui Liu Zhipeng Ruan Chengfei Zhao Source Type: research

Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach
CONCLUSION: AUC calculated using the Bayesian software allows for calculation with samples at a non-steady state, can integrate covariates, and is interconvertible with that estimated using an equation-based calculator, which is simpler and relies on fewer assumptions. Therefore, either method can be used, considering each method's strengths and limitations.PMID:38329916 | DOI:10.5414/CP204508 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Eojin Lee Uijeong Yu Ji In Park Sang-In Park Source Type: research

Clinical implications and future prospects of levonorgestrel and piroxicam as a combined emergency contraceptive regimen
Int J Clin Pharmacol Ther. 2024 Feb 8. doi: 10.5414/CP204537. Online ahead of print.NO ABSTRACTPMID:38329915 | DOI:10.5414/CP204537 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Jiawei Ke Jingrui Cai Xiaolin Liu Liwen Chen Tianhui Liu Zhipeng Ruan Chengfei Zhao Source Type: research

Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach
CONCLUSION: AUC calculated using the Bayesian software allows for calculation with samples at a non-steady state, can integrate covariates, and is interconvertible with that estimated using an equation-based calculator, which is simpler and relies on fewer assumptions. Therefore, either method can be used, considering each method's strengths and limitations.PMID:38329916 | DOI:10.5414/CP204508 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Eojin Lee Uijeong Yu Ji In Park Sang-In Park Source Type: research

Clinical implications and future prospects of levonorgestrel and piroxicam as a combined emergency contraceptive regimen
Int J Clin Pharmacol Ther. 2024 Feb 8. doi: 10.5414/CP204537. Online ahead of print.NO ABSTRACTPMID:38329915 | DOI:10.5414/CP204537 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Jiawei Ke Jingrui Cai Xiaolin Liu Liwen Chen Tianhui Liu Zhipeng Ruan Chengfei Zhao Source Type: research

Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach
CONCLUSION: AUC calculated using the Bayesian software allows for calculation with samples at a non-steady state, can integrate covariates, and is interconvertible with that estimated using an equation-based calculator, which is simpler and relies on fewer assumptions. Therefore, either method can be used, considering each method's strengths and limitations.PMID:38329916 | DOI:10.5414/CP204508 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Eojin Lee Uijeong Yu Ji In Park Sang-In Park Source Type: research

Clinical implications and future prospects of levonorgestrel and piroxicam as a combined emergency contraceptive regimen
Int J Clin Pharmacol Ther. 2024 Feb 8. doi: 10.5414/CP204537. Online ahead of print.NO ABSTRACTPMID:38329915 | DOI:10.5414/CP204537 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Jiawei Ke Jingrui Cai Xiaolin Liu Liwen Chen Tianhui Liu Zhipeng Ruan Chengfei Zhao Source Type: research

Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach
CONCLUSION: AUC calculated using the Bayesian software allows for calculation with samples at a non-steady state, can integrate covariates, and is interconvertible with that estimated using an equation-based calculator, which is simpler and relies on fewer assumptions. Therefore, either method can be used, considering each method's strengths and limitations.PMID:38329916 | DOI:10.5414/CP204508 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Eojin Lee Uijeong Yu Ji In Park Sang-In Park Source Type: research

Clinical implications and future prospects of levonorgestrel and piroxicam as a combined emergency contraceptive regimen
Int J Clin Pharmacol Ther. 2024 Feb 8. doi: 10.5414/CP204537. Online ahead of print.NO ABSTRACTPMID:38329915 | DOI:10.5414/CP204537 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Jiawei Ke Jingrui Cai Xiaolin Liu Liwen Chen Tianhui Liu Zhipeng Ruan Chengfei Zhao Source Type: research

Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach
CONCLUSION: AUC calculated using the Bayesian software allows for calculation with samples at a non-steady state, can integrate covariates, and is interconvertible with that estimated using an equation-based calculator, which is simpler and relies on fewer assumptions. Therefore, either method can be used, considering each method's strengths and limitations.PMID:38329916 | DOI:10.5414/CP204508 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - February 8, 2024 Category: Drugs & Pharmacology Authors: Eojin Lee Uijeong Yu Ji In Park Sang-In Park Source Type: research