Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials
CONCLUSION: Our findings indicate that evolocumab and alirocumab are significantly effective without increasing the risk of hemorrhagic stroke. Based on this, the PCSK9 inhibitors can be highly recommended for cholesterol management.PMID:38529927 | DOI:10.5414/CP204506 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Kwang-Hee Shin Hye Duck Choi Source Type: research

Therapeutic drug monitoring of vancomycin in surgical patients through a validated HPLC method
CONCLUSION: The developed method is sensitive and cost effective for quantification of vancomycin in human plasma. The results of sample analysis shows that the developed method can be used reliably for TDM of vancomycin.PMID:38529928 | DOI:10.5414/CP204534 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Muhammad Noman Akram Muhammad Imran Khokhar Mateen Abbas Muhammad Khurram Waqas Mian Waqar Mustafa Abdulhakeem S Alamri Majid Alhomrani Walaa F Alsanie Muhammad Usman Source Type: research

Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials
CONCLUSION: Our findings indicate that evolocumab and alirocumab are significantly effective without increasing the risk of hemorrhagic stroke. Based on this, the PCSK9 inhibitors can be highly recommended for cholesterol management.PMID:38529927 | DOI:10.5414/CP204506 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Kwang-Hee Shin Hye Duck Choi Source Type: research

Therapeutic drug monitoring of vancomycin in surgical patients through a validated HPLC method
CONCLUSION: The developed method is sensitive and cost effective for quantification of vancomycin in human plasma. The results of sample analysis shows that the developed method can be used reliably for TDM of vancomycin.PMID:38529928 | DOI:10.5414/CP204534 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Muhammad Noman Akram Muhammad Imran Khokhar Mateen Abbas Muhammad Khurram Waqas Mian Waqar Mustafa Abdulhakeem S Alamri Majid Alhomrani Walaa F Alsanie Muhammad Usman Source Type: research

Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials
CONCLUSION: Our findings indicate that evolocumab and alirocumab are significantly effective without increasing the risk of hemorrhagic stroke. Based on this, the PCSK9 inhibitors can be highly recommended for cholesterol management.PMID:38529927 | DOI:10.5414/CP204506 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Kwang-Hee Shin Hye Duck Choi Source Type: research

Therapeutic drug monitoring of vancomycin in surgical patients through a validated HPLC method
CONCLUSION: The developed method is sensitive and cost effective for quantification of vancomycin in human plasma. The results of sample analysis shows that the developed method can be used reliably for TDM of vancomycin.PMID:38529928 | DOI:10.5414/CP204534 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Muhammad Noman Akram Muhammad Imran Khokhar Mateen Abbas Muhammad Khurram Waqas Mian Waqar Mustafa Abdulhakeem S Alamri Majid Alhomrani Walaa F Alsanie Muhammad Usman Source Type: research

Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials
CONCLUSION: Our findings indicate that evolocumab and alirocumab are significantly effective without increasing the risk of hemorrhagic stroke. Based on this, the PCSK9 inhibitors can be highly recommended for cholesterol management.PMID:38529927 | DOI:10.5414/CP204506 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Kwang-Hee Shin Hye Duck Choi Source Type: research

Therapeutic drug monitoring of vancomycin in surgical patients through a validated HPLC method
CONCLUSION: The developed method is sensitive and cost effective for quantification of vancomycin in human plasma. The results of sample analysis shows that the developed method can be used reliably for TDM of vancomycin.PMID:38529928 | DOI:10.5414/CP204534 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Muhammad Noman Akram Muhammad Imran Khokhar Mateen Abbas Muhammad Khurram Waqas Mian Waqar Mustafa Abdulhakeem S Alamri Majid Alhomrani Walaa F Alsanie Muhammad Usman Source Type: research

Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials
CONCLUSION: Our findings indicate that evolocumab and alirocumab are significantly effective without increasing the risk of hemorrhagic stroke. Based on this, the PCSK9 inhibitors can be highly recommended for cholesterol management.PMID:38529927 | DOI:10.5414/CP204506 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Kwang-Hee Shin Hye Duck Choi Source Type: research

Therapeutic drug monitoring of vancomycin in surgical patients through a validated HPLC method
CONCLUSION: The developed method is sensitive and cost effective for quantification of vancomycin in human plasma. The results of sample analysis shows that the developed method can be used reliably for TDM of vancomycin.PMID:38529928 | DOI:10.5414/CP204534 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 26, 2024 Category: Drugs & Pharmacology Authors: Muhammad Noman Akram Muhammad Imran Khokhar Mateen Abbas Muhammad Khurram Waqas Mian Waqar Mustafa Abdulhakeem S Alamri Majid Alhomrani Walaa F Alsanie Muhammad Usman Source Type: research

Efficacy and safety of antiplatelet therapy in COVID-19: Insights from a  meta-analysis of randomized controlled trials
CONCLUSION: Antiplatelet therapy does not confer mortality benefit in COVID-19 patients but lowers major thrombotic events while increasing major bleeding risks. Ongoing large RCTs will provide more information on the therapeutic value of this therapy.PMID:38469705 | DOI:10.5414/CP204497 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - March 12, 2024 Category: Drugs & Pharmacology Authors: Guoying Kao Yunlin Chen Jinqi Fan Source Type: research