Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Laboratory and field validation of the recombinase polymerase amplification assay targeting the Schistosoma mansoni mitochondrial minisatellite region (SmMIT-RPA) for snail xenomonitoring for schistosomiasis
Int J Parasitol. 2024 Feb 3:S0020-7519(24)00018-3. doi: 10.1016/j.ijpara.2024.01.005. Online ahead of print.ABSTRACTImprovements in diagnostics for schistosomiasis in both humans and snail hosts are priorities to be able to reach the World Health Organization (WHO) goal of eliminating the disease as a public health problem by 2030. In this context, molecular isothermal amplification tests, such as Recombinase Polymerase Amplification (RPA), are promising for use in endemic areas at the point-of-need for their accuracy, robustness, simplicity, and time-effectiveness. The developed recombinase polymerase amplification assay ...
Source: International Journal for Parasitology - February 4, 2024 Category: Parasitology Authors: Silvia Gon çalves Mesquita Grace Gadd Fernanda Sales Coelho Adam Cieplinski Aidan Emery Elena Birgitta Lugli Tayn ãna César Simões Cristina Toscano Fonseca Roberta Lima Caldeira Bonnie Webster Source Type: research

Mitochondrial genetic diversity and phylogenetic relationships of Echinococcus multilocularis in Europe
Int J Parasitol. 2024 Jan 20:S0020-7519(24)00014-6. doi: 10.1016/j.ijpara.2024.01.003. Online ahead of print.ABSTRACTThe cestode Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a fatal zoonotic parasitic disease of the northern hemisphere. Red foxes are the main reservoir hosts and, likely, the main drivers of the geographic spread of the disease in Europe. Knowledge of genetic relationships among E. multilocularis isolates at a European scale is key to understanding the dispersal characteristics of E. multilocularis. Hence, the present study aimed to describe the genetic diversity of E. mult...
Source: International Journal for Parasitology - January 21, 2024 Category: Parasitology Authors: Azzurra Santoro Federica Santolamazza Simone M Cacci ò Giuseppe La Rosa Daniela Antolov á Herbert Auer Guna Bagrade Petra Bandelj Walter Basso Relja Beck Carlo V Citterio Rebecca K Davidson Gunita Deksne Caroline F Frey Eva Fuglei Walter Glawischnig Bru Source Type: research

Development of adult Dirofilaria immitis worms in the Rag2/Il-2r γ < sup > -/- < /sup > mouse model
Int J Parasitol. 2024 Jan 19:S0020-7519(24)00015-8. doi: 10.1016/j.ijpara.2024.01.004. Online ahead of print.ABSTRACTDirofilaria immitis is the causative agent for one of the major parasitic infections in dogs. It is currently not possible to reliably diagnose the infection before the development of fertile adult female worms and the presence of microfilariae which takes six to 7 months. However, at this point adult worms already reside in the pulmonary arteries and can cause significant damage. Novel in vivo models may facilitate the development of new diagnostic tools and improve treatment options for both the early and ...
Source: International Journal for Parasitology - January 21, 2024 Category: Parasitology Authors: Frederic Risch Carolin Ludwig-Erdmann Achim Hoerauf Heinz Sager Marc P H übner Source Type: research

Molecular characteristics of Cryptosporidium spp. in human cases in five Finnish hospital districts during 2021: first findings of Cryptosporidium mortiferum (Cryptosporidium chipmunk genotype I) in Finland
In conclusion, C. parvum and C. mortiferum were the major causes of cryptosporidiosis in the five studied Finnish hospital districts.PMID:38242277 | DOI:10.1016/j.ijpara.2024.01.002 (Source: International Journal for Parasitology)
Source: International Journal for Parasitology - January 19, 2024 Category: Parasitology Authors: Tessa H äkkänen Ruska Rimhanen-Finne Jenni Antikainen Eeva Ruotsalainen Anni Vainio Source Type: research

Strong mitonuclear discordance in the phylogeny of Neodermata and evolutionary rates of Polyopisthocotylea
In conclusion, Polyopisthocotylea appears to be the lineage with the fastest-evolving mtDNA sequences among all of Bilateria, but most of the substitutions were accumulated deep in the evolutionary history of this lineage. As the nuclear genome does not exhibit a similar pattern, the circumstances underpinning this evolutionary phenomenon remain a mystery.PMID:38185351 | DOI:10.1016/j.ijpara.2024.01.001 (Source: International Journal for Parasitology)
Source: International Journal for Parasitology - January 7, 2024 Category: Parasitology Authors: Dong Zhang Ivan Jakovli ć Hong Zou Fei Liu Chuan-Yu Xiang Qunzong Gusang Sonam Tso Shenggui Xue Wen-Jin Zhu Zhenxin Li Jihua Wu Gui-Tang Wang Source Type: research

Strong mitonuclear discordance in the phylogeny of Neodermata and evolutionary rates of Polyopisthocotylea
In conclusion, Polyopisthocotylea appears to be the lineage with the fastest-evolving mtDNA sequences among all of Bilateria, but most of the substitutions were accumulated deep in the evolutionary history of this lineage. As the nuclear genome does not exhibit a similar pattern, the circumstances underpinning this evolutionary phenomenon remain a mystery.PMID:38185351 | DOI:10.1016/j.ijpara.2024.01.001 (Source: International Journal for Parasitology)
Source: International Journal for Parasitology - January 7, 2024 Category: Parasitology Authors: Dong Zhang Ivan Jakovli ć Hong Zou Fei Liu Chuan-Yu Xiang Qunzong Gusang Sonam Tso Shenggui Xue Wen-Jin Zhu Zhenxin Li Jihua Wu Gui-Tang Wang Source Type: research

Strong mitonuclear discordance in the phylogeny of Neodermata and evolutionary rates of Polyopisthocotylea
In conclusion, Polyopisthocotylea appears to be the lineage with the fastest-evolving mtDNA sequences among all of Bilateria, but most of the substitutions were accumulated deep in the evolutionary history of this lineage. As the nuclear genome does not exhibit a similar pattern, the circumstances underpinning this evolutionary phenomenon remain a mystery.PMID:38185351 | DOI:10.1016/j.ijpara.2024.01.001 (Source: International Journal for Parasitology)
Source: International Journal for Parasitology - January 7, 2024 Category: Parasitology Authors: Dong Zhang Ivan Jakovli ć Hong Zou Fei Liu Chuan-Yu Xiang Qunzong Gusang Sonam Tso Shenggui Xue Wen-Jin Zhu Zhenxin Li Jihua Wu Gui-Tang Wang Source Type: research