Local nasal immunotherapy for allergic rhinitis: A systematic review and meta ‐analysis
ConclusionsLNIT is a safe, alternative allergen immunotherapy route without significant adverse events. It improves clinical symptoms, reduces medication usage, and increases the nasal provocation threshold.This article is protected by copyright. All rights reserved (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 11, 2022 Category: Allergy & Immunology Authors: Navarat Kasemsuk, Premyot Ngaotepprutaram, Dichapong Kanjanawasee, Triphoom Suwanwech, Stephen R Durham, Giorgio Walter Canonica, Pongsakorn Tantilipikorn Tags: ORIGINAL ARTICLE Source Type: research

Injection of cyanoacrylate glue for hereditary hemorrhagic telangiectasia
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 7, 2022 Category: Allergy & Immunology Authors: Maeva Anciaux, Jean ‐Pascal Lebreton, Denis Tonnerre, Justine Leclerc, Xavier Dufour, Florent Carsuzaa Tags: RESEARCH NOTE Source Type: research

Periostin as a biomarker in chronic rhinosinusitis: A contemporary systematic review
ConclusionsTissue and serum periostin levels, and POSTN expression appear elevated in CRSwNP, especially in eosinophilic inflammation, compared to CRSsNP and controls. Disease severity and comorbidities are also reflected in periostin and POSTN values. Carefully designed prospective studies may establish the role of periostin as a biomarker in CRSwNP and allow its incorporation in clinical practice.This article is protected by copyright. All rights reserved (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 6, 2022 Category: Allergy & Immunology Authors: Gerasimos Danielides, Spyridon Lygeros, Menelaos Kanakis, Stephanos Naxakis Tags: ORIGINAL ARTICLE Source Type: research

Inhibiting the type 2 inflammatory pathway with dupilumab is associated with an increase in interleukin ‐4 and interleukin‐18 production
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - May 1, 2022 Category: Allergy & Immunology Authors: Jymirah Morris, Tolani F. Olonisakin, John A. Moore, BaDoi Phan, Dana M. Parker, Bliss A. Uribe, Stephanie J. Barel, Eve M.R. Bowers, Kathleen M. Buchheit, Tanya M. Laidlaw, Stella E. Lee Tags: RESEARCH NOTE Source Type: research

Outcomes of endoscopic endonasal resection of pediatric craniopharyngiomas
Conclusion: Endoscopic endonasal resection for pediatric craniopharyngiomas can achieve high rates of resection with low rates of disease recurrence when compared to the outcomes of open transcranial resection reported in the literature. However, hypothalamic-pituitary dysfunction remains a significant postoperative morbidity in both approaches.This article is protected by copyright. All rights reserved (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 29, 2022 Category: Allergy & Immunology Authors: Tapan D. Patel, Bianca Rullan ‐Oliver, Heather Ungerer, Phillip B. Storm, Michael A. Kohanski, Nithin D. Adappa, James N. Palmer Tags: ORIGINAL ARTICLE Source Type: research

Comparison of validated psychophysical olfactory tests and olfactory ‐specific quality of life
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 29, 2022 Category: Allergy & Immunology Authors: Michael C. Shih, Zachary M. Soler, Matthew Germroth, Jacob Snyder, Shaun A. Nguyen, Rodney J. Schlosser Tags: RESEARCH NOTE Source Type: research

Issue Information
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 26, 2022 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research

A novel triple pedicled mucoperiosteal flaps in reconstruction of neo ‐ostium after DrafⅢ frontal sinusotomy for refractory frontal sinusitis
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 25, 2022 Category: Allergy & Immunology Authors: Hao Zheng, Shao ‐peng Huang, Xiao‐yan Wang, Qing‐hua Liu, Yong Chen, Qing Ye Tags: CLINICAL LETTER Source Type: research

CRS ‐PRO and SNOT‐22 correlations with type 2 inflammatory mediators in chronic rhinosinusitis
ConclusionThe CRS-PRO total score showed a significant correlation with T2 biomarkers especially when assessed post-ESS and among CRSwNP patients. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 25, 2022 Category: Allergy & Immunology Authors: Samuel D. Racette, Alexander L. Schneider, Meera Ganesh, Julia H. Huang, David S. Lehmann, Caroline P.E. Price, Samuel G. Rodegherio, Abhita T. Reddy, Jacob G. Eide, David B. Conley, Kevin C. Welch, Robert C. Kern, Stephanie Shintani ‐Smith, Tags: ORIGINAL ARTICLE Source Type: research

Combined medical therapy in the treatment of allergic rhinitis: Systematic review and meta ‐analyses
ConclusionAfter ATH monotherapy fails to control symptoms, addition of decongestant, saline, or LTRA can improve the outcomes. When INCS monotherapy is ineffective, addition of intranasal ATH can improve nasal symptoms; LTRA can improve ocular symptoms; and saline irrigation can improve QoL.This article is protected by copyright. All rights reserved (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 22, 2022 Category: Allergy & Immunology Authors: Wirach Chitsuthipakorn, Minh P. Hoang, Dichapong Kanjanawasee, Kachorn Seresirikachorn, Kornkiat Snidvongs Tags: ORIGINAL ARTICLE Source Type: research

Analysis of competing endogenous RNA (ceRNA) crosstalk in eosinophilic chronic rhinosinusitis with nasal polyps
ConclusionIn summary, the present study provided the first comprehensive assessment of the ceRNA crosstalk in eosinophilic CRSwNP. These findings will be of interest to the understanding of the potential pathophysiology of this disease. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 21, 2022 Category: Allergy & Immunology Authors: Ke Li, Fang ‐Fang Liu Tags: ORIGINAL ARTICLE Source Type: research

Reply to “EDS‐FLU: An important step in appropriate medical therapy for chronic rhinosinusitis with nasal polyps”
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 18, 2022 Category: Allergy & Immunology Authors: Richard Orlandi Tags: CORRESPONDENCE AND REPLY Source Type: research

Particulate matter air pollution exposure disrupts the Nrf2 Pathway in Sinonasal Epithelium via epigenetic alterations in a murine model
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 16, 2022 Category: Allergy & Immunology Authors: Bongsoo Park, Nyall R. London, Anuj Tharakan, Palanivel Rengasamy, Sanjay Rajagopalan, Shyam Biswal, Jayant M. Pinto, Murugappan Ramanathan Tags: RESEARCH NOTE Source Type: research

Triamcinolone ‐impregnated bioabsorbable middle meatus packing following endoscopic sinus surgery: A prospective randomized controlled trial
ConclusionThe results of this study demonstrated no significant difference in healing, crusting, polyps, edema, or secretions between the triamcinolone-treated and non-triamcinolone-treated sinuses. There were no adverse effects from the use of triamcinolone-impregnated absorbable packing. Further studies will be necessary to determine the impact of triamcinolone-impregnated absorbable packing following ESS. (Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 10, 2022 Category: Allergy & Immunology Authors: Justin P. McCormick, Jeffrey D. Suh, Hong ‐Ho Yang, Jivianne T. Lee, Marilene B. Wang Tags: ORIGINAL ARTICLE Source Type: research

Inhibiting the Type 2 Inflammatory Pathway with Dupilumab is Associated with an Increase in IL ‐4 and IL‐18 Production
(Source: International Forum of Allergy and Rhinology)
Source: International Forum of Allergy and Rhinology - April 8, 2022 Category: Allergy & Immunology Authors: Jymirah Morris, Tolani F. Olonisakin, John A. Moore, BaDoi Phan, Dana M. Parker, Bliss A. Uribe, Stephanie J. Barel, Eve M.R. Bowers, Kathleen M. Buchheit, Tanya M. Laidlaw, Stella E. Lee Tags: RESEARCH NOTE Source Type: research