Urological tumors treatment in Brazil during the SARS-Cov-2 outbrake
Conclusion: Elective uro-oncological procedures at the COVID-19 epidemic period in a COVID-19-free Institute are safe, and patients who need urgent procedures, with a long period of hospitalization, need special care to avoid COVID-19 infection and its outcomes. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Evaluation of uro-oncological surgical treatment during the Sars-CoV-2 pandemic in a Brazilian tertiary oncology institution, the new world epicenter
Conclusion: Elective uro-oncological procedures at the COVID-19 epidemic period in a COVID-19-free Institute are safe, and patients who need urgent procedures, with a long period of hospitalization, need special care to avoid COVID-19 infection and its outcomes. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
National Consensus on Non-metastatic Castration-Resistant Prostate Cancer: more than just a snapshot
Conclusions: The results and recommendations presented can be used by Brazilian physicians to support the management of M0 CRPC patients. Individual clinical decision making should be supported by available data, however, for Brazil, guidelines for diagnosis and management of M0 CRPC patients have not been developed. This document will serve as a point of reference when confronting this disease stage. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Consensus on diagnosis and management of non-metastatic castration resistant prostate cancer in Brazil: focus on patient, selection, treatment efficacy, side effects and physician's perception according to patient comorbidities
Conclusions: The results and recommendations presented can be used by Brazilian physicians to support the management of M0 CRPC patients. Individual clinical decision making should be supported by available data, however, for Brazil, guidelines for diagnosis and management of M0 CRPC patients have not been developed. This document will serve as a point of reference when confronting this disease stage. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Editorial comment: High pressure endoscopic irrigation: impact on renal histology
Conclusions: Pressurized endoscopic irrigation leads to significant extravasation of fluid into the renal parenchyma. Higher intra-renal pressures were associated with increased penetration of irrigant during ureteroscopy in an ex-vivo porcine model. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
High pressure endoscopic irrigation: impact on renal histology
Conclusions: Pressurized endoscopic irrigation leads to significant extravasation of fluid into the renal parenchyma. Higher intra-renal pressures were associated with increased penetration of irrigant during ureteroscopy in an ex-vivo porcine model. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Survival nomogram for patients with bone metastatic renal cell carcinoma: A population-based study
Conclusions: The nomograms for predicting prognosis provided an accurate prediction of OS and CSS in RCC patients with bone metastasis, and contributed clinicians to optimize individualized treatment plans. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Local tissue reaction and histopathological characteristics of three different bulking agents: a rabbit model
Conclusion: The long-term results demonstrated that LPM was more similar to Deflux with the least local tissue reaction, inflammation, and fibrosis grade. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Anatomic study of verumontanum during endoscopic surgeries in patients with benign prostatic hyperplasia
Conclusion: Veromontanum has smaller measurements in patients with BPH regardless of treatment. In the control group, there was an increase in verumontanum diameters with an increase in BMI. The volcano type of verumontanum was the most frequent regardless of groups and BMI. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Editorial Comment: Evaluation of HIF-1α and VEGF-A expression in radiation-induced cystitis: A case-control study
ABSTRACT The standard treatment for locally advanced cervical cancer (CC) is chemoradiotherapy. Once the bladder receives part of the radiation, a typical inflammatory condition that configures radiation-induced cystitis may develop. Chronic radiation-induced cystitis is commonly characterized by the bladder new submucosal vascularization, which is typically fragile and favors hematuria. The current study aims to investigate if Hypoxia-Induced Factor (HIF-1 α ) and its transcriptional target Vascular Endothelial Growth Factor A (VEGF-A) could be a primary pathway leading to increased submucosal vascularization. HIF-1 α ...
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Evaluation of HIF-1α and VEGF-A expression in radiation-induced cystitis: A case-control study
ABSTRACT The standard treatment for locally advanced cervical cancer (CC) is chemoradiotherapy. Once the bladder receives part of the radiation, a typical inflammatory condition that configures radiation-induced cystitis may develop. Chronic radiation-induced cystitis is commonly characterized by the bladder new submucosal vascularization, which is typically fragile and favors hematuria. The current study aims to investigate if Hypoxia-Induced Factor (HIF-1 α ) and its transcriptional target Vascular Endothelial Growth Factor A (VEGF-A) could be a primary pathway leading to increased submucosal vascularization. HIF-1 α ...
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Can platelet-rich plasma coating improve polypropylene mesh integration? An immunohistochemical analysis in rabbits
Conclusion: The addition of autologous PRP gel to PP meshes can be simply and safely achieved and seems to have a positive effect on implantation site angiogenesis. Further investigations are required to ascertain PPR coated meshes clinical efficacy in prolapses and stress urinary incontinence surgeries. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
What does a varicocele do to a man's fertility? There is much more than meets the eye
Conclusions: Patients with varicocele have an increase in sperm DNA fragmentation levels, particularly in oxidative stress-induced sperm DNA damage. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Oxidative origin of sperm DNA fragmentation in the adult varicocele
Conclusions: Patients with varicocele have an increase in sperm DNA fragmentation levels, particularly in oxidative stress-induced sperm DNA damage. (Source: International Braz J Urol)
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
Editorial Comment: Vaginoplasty tips and tricks
ABSTRACT Vaginoplasty is a commonly performed surgery for the transfeminine patient. In this review, we discuss how to achieve satisfactory surgical outcomes, and highlight solutions to common complications involved with the surgery, including: wound separation, vaginal stenosis, hematoma, and rectovaginal fistula. Pre-operative evaluation and standard technique are outlined. Goal outcomes regarding aesthetics, creation of a neocavity, urethral management, labial appearance, vaginal packing and clitoral sizing are all described. Peritoneal vaginoplasty technique and visceral interposition technique are detailed as alternat...
Source: International Braz J Urol - February 6, 2021 Category: Urology & Nephrology Source Type: research
