Renal function-adapted D-dimer cutoffs in combination with a clinical prediction rule to exclude pulmonary embolism in patients presenting to the emergency department
AbstractD-dimer levels significantly increase with declining renal function and hence, renal function-adjusted D-dimer cutoffs to rule out pulmonary embolism were suggested. Aim of this study was to"post hoc" validate previously defined renal function-adjusted D-dimer levels to safely rule out pulmonary embolism in patients presenting to the emergency department. In this retrospective, observational analysis, all patients with low to intermediate pre-test probability receiving D-dimer measurement and computed tomography angiography (CTA) to rule out pulmonary embolism between January 2017 and December 2020 were i...
Source: Internal and Emergency Medicine - February 14, 2024 Category: Emergency Medicine Source Type: research
Statins, ACE/ARBs drug use, and risk of pneumonia in hospitalized older patients: a retrospective cohort study
This study confirmed in the real-world setting that these largely used medications may reduce the risk of pneumonia in older people, who chronically take them for cardiovascula r conditions. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 14, 2024 Category: Emergency Medicine Source Type: research
Sodium –glucose cotransporter-2 inhibitors in heart failure patients across the range of body mass index: a systematic review and meta-analysis of randomized controlled trials
AbstractSodium –glucose cotransporter-2 (SGLT2) inhibitors improve outcomes in patients with heart failure, with or without diabetes. We sought to assess whether there is an interaction of these effects with body mass index (BMI). A systematic review of the MEDLINE and Scopus databases (last search: November 15t h, 2022) was performed according to the PRISMA statement. Studies eligible for this review were randomized control trials (RCTs) with patients with chronic heart failure with either preserved or reduced ejection fraction randomly assigned to SGLT2 inhibitors or placebo. Data were extracted independe ntly by two r...
Source: Internal and Emergency Medicine - February 14, 2024 Category: Emergency Medicine Source Type: research
Renal function-adapted D-dimer cutoffs in combination with a clinical prediction rule to exclude pulmonary embolism in patients presenting to the emergency department
AbstractD-dimer levels significantly increase with declining renal function and hence, renal function-adjusted D-dimer cutoffs to rule out pulmonary embolism were suggested. Aim of this study was to"post hoc" validate previously defined renal function-adjusted D-dimer levels to safely rule out pulmonary embolism in patients presenting to the emergency department. In this retrospective, observational analysis, all patients with low to intermediate pre-test probability receiving D-dimer measurement and computed tomography angiography (CTA) to rule out pulmonary embolism between January 2017 and December 2020 were i...
Source: Internal and Emergency Medicine - February 14, 2024 Category: Emergency Medicine Source Type: research
Statins, ACE/ARBs drug use, and risk of pneumonia in hospitalized older patients: a retrospective cohort study
This study confirmed in the real-world setting that these largely used medications may reduce the risk of pneumonia in older people, who chronically take them for cardiovascula r conditions. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 14, 2024 Category: Emergency Medicine Source Type: research
New race-free creatinine- and cystatin C-based equations for the estimation of glomerular filtration rate and association with cardiovascular mortality in the AtheroGene study
AbstractRenal function is associated with cardiovascular outcomes and mortality. Among equations used to eGFR, CKD –EPI equations show more accurate association with cardiovascular risk and mortality than MDRD. Recently, new CKD–EPI equations were proposed which do not include race and would be considered sufficiently accurate to estimate eGFR in clinical practice. It is unknown if these new race-free equati ons are comparably well associated with cardiovascular outcomes in high-risk individuals. The analysis was performed in the AtheroGene Study cohort including patients at high cardiovascular risk. eGFR was determine...
Source: Internal and Emergency Medicine - February 13, 2024 Category: Emergency Medicine Source Type: research
Variability of the anticoagulant effect according to body weight in patients treated with direct oral anticoagulants
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 9, 2024 Category: Emergency Medicine Source Type: research
The effects of venovenous bypass use in liver transplantation with piggyback technique: a propensity score-weighted analysis
This study suggests similar mortality and length of stay but a higher risk for postoperative acu te kidney injury in patients undergoing piggyback LT with VVB. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 9, 2024 Category: Emergency Medicine Source Type: research
Variability of the anticoagulant effect according to body weight in patients treated with direct oral anticoagulants
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 9, 2024 Category: Emergency Medicine Source Type: research
The effects of venovenous bypass use in liver transplantation with piggyback technique: a propensity score-weighted analysis
This study suggests similar mortality and length of stay but a higher risk for postoperative acu te kidney injury in patients undergoing piggyback LT with VVB. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 9, 2024 Category: Emergency Medicine Source Type: research
DOACs levels in patients with hip fracture: is there a relation with renal function and time from last drug intake?
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 7, 2024 Category: Emergency Medicine Source Type: research
What is your next step? In a case of hemolysis and pancytopenia
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 7, 2024 Category: Emergency Medicine Source Type: research
DOACs levels in patients with hip fracture: is there a relation with renal function and time from last drug intake?
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 7, 2024 Category: Emergency Medicine Source Type: research
What is your next step? In a case of hemolysis and pancytopenia
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 7, 2024 Category: Emergency Medicine Source Type: research
