4C mortality score and COVID-19 mortality risk score: an analysis in four different age groups of an Italian population
AbstractTo evaluate the prognostic stratification ability of 4C Mortality Score and COVID-19 Mortality Risk Score in different age groups. Retrospective study, including all patients, presented to the Emergency Department of the University Hospital Careggi, between February, 2020 and May, 2021, and admitted for SARS-CoV2. Patients were divided into four subgroups based on the quartiles of age distribution: patients  <  57 years (G1,n = 546), 57–71 years (G2,n = 508), 72–81 years (G3,n = 552), and >  82 years (G4,n = 578). We calculated the 4C Mortality Score and COVID-19 Mortality Risk...
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

Diabetes mellitus in patients with heart failure and reduced ejection fraction: a post hoc analysis from the WARCEF trial
In conclusion, we found that DM is common in HFrEF patients, and is associated with other cardiovascular comorbidities and risk factors, and with a worse prognosis. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

Antibiotics in COPD exacerbations requiring mechanical ventilation: a dogma to be re-evaluated
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

Clinical characteristics of survivors versus non-survivors after acute diquat poisoning: a comparative study —comment
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

4C mortality score and COVID-19 mortality risk score: an analysis in four different age groups of an Italian population
AbstractTo evaluate the prognostic stratification ability of 4C Mortality Score and COVID-19 Mortality Risk Score in different age groups. Retrospective study, including all patients, presented to the Emergency Department of the University Hospital Careggi, between February, 2020 and May, 2021, and admitted for SARS-CoV2. Patients were divided into four subgroups based on the quartiles of age distribution: patients  <  57 years (G1,n = 546), 57–71 years (G2,n = 508), 72–81 years (G3,n = 552), and >  82 years (G4,n = 578). We calculated the 4C Mortality Score and COVID-19 Mortality Risk...
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

Diabetes mellitus in patients with heart failure and reduced ejection fraction: a post hoc analysis from the WARCEF trial
In conclusion, we found that DM is common in HFrEF patients, and is associated with other cardiovascular comorbidities and risk factors, and with a worse prognosis. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

Antibiotics in COPD exacerbations requiring mechanical ventilation: a dogma to be re-evaluated
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

Clinical characteristics of survivors versus non-survivors after acute diquat poisoning: a comparative study —comment
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - February 23, 2024 Category: Emergency Medicine Source Type: research

Descriptive analysis and evaluation of Health Link referrals to the emergency department before and during the COVID-19 pandemic
AbstractBackgroundIn Alberta, Health Link (HL) provides a 24-h, nurse-staffed, phone resource to the public for health-care advice. HL directs callers to either seek care in the emergency department (ED), with a primary care provider or provide self-care at home. This work aims to describe HL ED referrals prior to and during the COVID-19 pandemic.MethodsData from January 1, 2018 –December 31, 2019, and July 1, 2020–June 30, 2022, were selected. HL calls were categorized as likely appropriate if the patient was referred and presented to the ED within 24 h and had a Canadian Triage and Acuity Scale (CTAS) of 1–3; or a...
Source: Internal and Emergency Medicine - February 22, 2024 Category: Emergency Medicine Source Type: research

A novel prognostic model to predict mortality in patients with acute-on-chronic liver failure in intensive care unit
AbstractAcute-on-chronic liver failure (ACLF) implies high short-term mortality rates and usually requires intensive care unit (ICU) admission. Proper prognosis for these patients is crucial for early referral for liver transplantation. The superiority of CLIF-C ACLF score in Asian patients with ACLF admitted to an ICU remains inconclusive when compared to other scoring systems. The purpose of the study is (i) to compare the predictive performance of original MELD, MELD-Lactate, CLIF-C ACLF, CLIF-C ACLF-Lactate, and APACHE-II scores for short-term mortality assessment. (ii) to build and validate a novel scoring system and ...
Source: Internal and Emergency Medicine - February 22, 2024 Category: Emergency Medicine Source Type: research

Descriptive analysis and evaluation of Health Link referrals to the emergency department before and during the COVID-19 pandemic
AbstractBackgroundIn Alberta, Health Link (HL) provides a 24-h, nurse-staffed, phone resource to the public for health-care advice. HL directs callers to either seek care in the emergency department (ED), with a primary care provider or provide self-care at home. This work aims to describe HL ED referrals prior to and during the COVID-19 pandemic.MethodsData from January 1, 2018 –December 31, 2019, and July 1, 2020–June 30, 2022, were selected. HL calls were categorized as likely appropriate if the patient was referred and presented to the ED within 24 h and had a Canadian Triage and Acuity Scale (CTAS) of 1–3; or a...
Source: Internal and Emergency Medicine - February 22, 2024 Category: Emergency Medicine Source Type: research

A novel prognostic model to predict mortality in patients with acute-on-chronic liver failure in intensive care unit
AbstractAcute-on-chronic liver failure (ACLF) implies high short-term mortality rates and usually requires intensive care unit (ICU) admission. Proper prognosis for these patients is crucial for early referral for liver transplantation. The superiority of CLIF-C ACLF score in Asian patients with ACLF admitted to an ICU remains inconclusive when compared to other scoring systems. The purpose of the study is (i) to compare the predictive performance of original MELD, MELD-Lactate, CLIF-C ACLF, CLIF-C ACLF-Lactate, and APACHE-II scores for short-term mortality assessment. (ii) to build and validate a novel scoring system and ...
Source: Internal and Emergency Medicine - February 22, 2024 Category: Emergency Medicine Source Type: research

Real-time machine learning-assisted sepsis alert enhances the timeliness of antibiotic administration and diagnostic accuracy in emergency department patients with sepsis: a cluster-randomized trial
AbstractMachine learning (ML) has been applied in sepsis recognition across different healthcare settings with outstanding diagnostic accuracy. However, the advantage of ML-assisted sepsis alert in expediting clinical decisions leading to enhanced quality for emergency department (ED) patients remains unclear. A cluster-randomized trial was conducted in a tertiary-care hospital. Adult patient data were subjected to an ML model for sepsis alert. Patient visits were assigned into one of two groups. In the intervention cluster, staff received alerts on a display screen if patients met the ML threshold for sepsis diagnosis, wh...
Source: Internal and Emergency Medicine - February 21, 2024 Category: Emergency Medicine Source Type: research