Management of the Psychological Impact of Inflammatory Bowel Disease: Perspective of Doctors and Patients—The ENMENTE Project
Conclusions: A discrepancy exists between physician and patient perceptions of the impact of psychological aspects in IBD, with patients perceiving higher impact and more under treatment than physicians. Given the influence of these aspects on patient well-being, it seems advisable to enrich professionals' training, improve the clinical management of psychological aspects of IBD, and probably include psychologists in IBD care teams. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - August 26, 2017 Category: Gastroenterology Tags: IBD LIVE Articles Source Type: research
Characterizing the Posttransfer Period Among Patients with Pediatric Onset IBD: The Impact of Academic Versus Community Adult Care on Emergent Health Resource Utilization
Conclusions: Posttransfer health care setting does not seem to significantly impact emergent health resource utilization in the posttransfer period. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - August 26, 2017 Category: Gastroenterology Tags: IBD LIVE Articles Source Type: research
Individualized Infliximab Treatment Guided by Patient-managed eHealth in Children and Adolescents with Inflammatory Bowel Disease
Background: To individualize timing of infliximab (IFX) treatment in children and adolescents with inflammatory bowel disease (IBD) using a patient-managed eHealth program.
Methods: Patients with IBD, 10 to 17 years old, treated with IFX were prospectively included. Starting 4 weeks after their last infusion, patients reported a weekly symptom score and provided a stool sample for fecal calprotectin analysis. Based on symptom scores and fecal calprotectin results, the eHealth program calculated a total inflammation burden score that determined the timing of the next IFX infusion (4–12 wk after the previous infusion). Qu...
Source: Inflammatory Bowel Diseases - August 26, 2017 Category: Gastroenterology Tags: IBD LIVE Articles Source Type: research
Opening Doors for Urgent IBD Access: Harder than It Looks
No abstract available (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - August 26, 2017 Category: Gastroenterology Tags: Commentary Source Type: research
Health Care Services in IBD: Factors Associated with Service Utilization and Preferences for Service Options for Routine and Urgent Care
Conclusions: Persons with inflammatory bowel disease are receptive to options other than the ED when experiencing inflammatory bowel disease symptoms; however, attending the ED remains a prominent choice. Improved access to specialized care may improve timeliness of care and reduce ED attendance. Future research should include the impact of health anxiety on health care utilization. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - August 26, 2017 Category: Gastroenterology Tags: IBD LIVE Article Source Type: research
Letter to Editor Regarding Narula et al, IBD 2017, Budenoside Use Is a Key Quality Marker in the Management of IBD
No abstract available (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Online Only: Letter to the Editor Source Type: research
Serum Adalimumab Levels Predict Successful Remission and Safe Deintensification in Inflammatory Bowel Disease Patients in Clinical Practice
Background: Little is known about the association between the pharmacokinetic features of adalimumab (ADL) and disease outcome in patients with inflammatory bowel disease (IBD).
Aims: To assess the association between random serum ADL levels and clinical or biochemical remission with clinical decision making in daily practice according to these levels; and to determine the cutoff value for successful dose reduction in patients with IBD treated with ADL.
Methods: We conducted a prospective observational study of patients with IBD who received long-term maintenance therapy with ADL.
Results: Data were available for 157 se...
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
Mucosal Healing in Clinical Practice: A Single-Center Pediatric IBD Experience
Conclusions: MH is feasible in pediatric CD and UC, and rates of cumulative MH in pediatric patients are similar to previously published adult data. In children with inflammatory bowel disease in clinical remission, approximately one-third demonstrate active disease at endoscopy. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
The Association Between Maternal Chronic Inflammatory Bowel Disease and Long-term Health Outcomes in Children—A Nationwide Cohort Study
Conclusions: Children born to mothers with IBD are more likely to be diagnosed with IBD themselves, compared with children born to women without IBD. Our data otherwise do not provide evidence for an increased risk of any of the other examined diseases in the offspring. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
Incidence of and Predictors for Early Discontinuation of Biological Therapies in Veteran Patients with Inflammatory Bowel Disease
Conclusions: In conclusion, in a large multicenter VA cohort, we found that 24% of patients who are prescribed a biological stop their treatment early, most commonly for primary nonresponse or for an adverse drug reaction. Consideration should be given to treating patients with a concomitant thiopurine if at all possible, as this reduces the likelihood of early discontinuation. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
Comparative Acceptability and Perceived Clinical Utility of Monitoring Tools: A Nationwide Survey of Patients with Inflammatory Bowel Disease
Background: Objective control of intestinal inflammation during inflammatory bowel disease (IBD) is becoming the main driver for medical treatment. However, the monitoring tools-related burden remains poorly investigated. We aimed to evaluate their comparative acceptability and utility according to patients with IBD.
Methods: After a preliminary phase, the final questionnaire encompassing self-administered and physician questionnaires was prospectively and consecutively submitted to 916 patients with IBD from 20 public and private centers. Acceptability and utility visual analog scales (VAS) were expressed as median with ...
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
Point Prevalence of Pediatric Inflammatory Bowel Disease in New Zealand in 2015: Initial Results from the PINZ Study
Conclusions: The point prevalence of pediatric IBD in New Zealand represents the first-ever national, population-based prevalence rates of pediatric IBD published. Results from the Paediatric IBD in New Zealand (PINZ) study are also the first to show markedly higher prevalence rates of IBD in the southern part of a country compared with its northern counterpart. Ongoing prospective ascertainment of the incidence of pediatric IBD is required. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
Structural Basis of Bone Fragility in Young Subjects with Inflammatory Bowel Disease: A High-resolution pQCT Study of the SWISS IBD Cohort (SIBDC)
Conclusions: Young patients with IBD have low aBMD and altered trabecular bone microarchitecture compared with healthy controls. The latter is independently associated with fractures and may predispose increased susceptibility to fragility fractures throughout life. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
Transmural Healing Is Associated with Improved Long-term Outcomes of Patients with Crohn's Disease
Background: Mucosal healing (MH) is currently accepted as one of the best treatment targets in Crohn's disease. However, even in patients with sustained MH, residual bowel wall inflammation can still be detected by cross-sectional imaging. The long-term benefits of obtaining transmural healing (TH) have not been previously assessed.
Methods: We performed an observational study including 214 patients with Crohn's disease with a magnetic resonance enterography (MRE) and colonoscopy performed within a 6-month interval. Patients were classified as having TH (inactive MRE and colonoscopy), MH (active MRE with inactive colonosc...
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
Clinical Outcomes of Golimumab as First, Second or Third Anti-TNF Agent in Patients with Moderate-to-Severe Ulcerative Colitis
Conclusions: In this real-life cohort of patients with UC, golimumab therapy was effective for inducing and maintaining clinical response. Although anti-TNF–naive patients had better outcomes, golimumab was also effective in anti-TNF–experienced patients. Only the patients given golimumab after previous failure of 2 anti-TNF agents had significantly worse outcomes. Golimumab dose escalation was beneficial and safe. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 19, 2017 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research
